H. Jo

G. Stone, D. Giddens, H. Jo, 2021, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

Stone Age diet.

Ollie Jay, Hanjoong Jo, Jan Helgerud, 1994, Journal of the Royal Society of Medicine.

Angiotensin type I receptor blockade in conjunction with enhanced Akt activation restores coronary collateral growth in the metabolic syndrome.

H. Jo, K. Walsh, J. Russell, 2011, American journal of physiology. Heart and circulatory physiology.

Redox-sensitive Akt and Src regulate coronary collateral growth in metabolic syndrome.

H. Jo, B. Potter, Patricia C Villalta, 2009, American journal of physiology. Heart and circulatory physiology.

High glucose induced NF-kappaB DNA-binding activity in HAEC is maintained under low shear stress but inhibited under high shear stress: role of nitric oxide.

H. Jo, S. Mohan, M. Natarajan, 2003, Atherosclerosis.

8-Hydroxy-2-deoxyguanosine prevents plaque formation and inhibits vascular smooth muscle cell activation through Rac1 inactivation.

Sun Choi, H. Jo, Yoonji Lee, 2012, Free radical biology & medicine.

Biological aspects of reactive nitrogen species.

H. Jo, B. Freeman, V. Darley-Usmar, 1999, Biochimica et biophysica acta.

Detection of low levels of nitric oxide using an electrochemical sensor.

Y. Boo, H. Jo, S. Tressel, 2011, Methods in molecular biology.

The NADPH oxidase Nox4 has anti-atherosclerotic functions.

A. Shah, H. Jo, R. Brandes, 2015, European heart journal.

Part II • Chapter 3 – Exercise and xanthine oxidase in the vasculature: superoxide and nitric oxide interactions

H. Jo, V. Darley-Usmar, C. White, 2000 .

Inorganic Phosphate Induces Mammalian Growth Plate Chondrocyte Apoptosis in a Mitochondrial Pathway Involving Nitric Oxide and JNK MAP Kinase

H. Jo, B. Boyan, Z. Schwartz, 2011, Calcified Tissue International.

TP 508 Preserves Chondrocyte Cell Viability by Blocking Apoptosis via an NO-dependent Pathway

H. Jo, B. Boyan, M. Zhong, 2006 .

Endothelial NOS-dependent activation of c-Jun NH(2)- terminal kinase by oxidized low-density lipoprotein.

H. Jo, A. Ramachandran, Y. Go, 2001, American journal of physiology. Heart and circulatory physiology.

Disturbed Flow Enhances Inflammatory Signaling and Atherogenesis by Increasing Thioredoxin-1 Level in Endothelial Cell Nuclei

Dean P. Jones, H. Jo, D. Son, 2014, PloS one.

GTP Cyclohydrolase I Phosphorylation and Interaction With GTP Cyclohydrolase Feedback Regulatory Protein Provide Novel Regulation of Endothelial Tetrahydrobiopterin and Nitric Oxide

D. Harrison, H. Jo, A. Husain, 2010, Circulation research.

Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH(2)-terminal kinase.

H. Jo, H. Park, Y. Go, 1999, The American journal of physiology.

Vascular Semaphorin 7A Upregulation by Disturbed Flow Promotes Atherosclerosis Through Endothelial &bgr;1 Integrin

H. Jo, A. V. van Zonneveld, J. V. van Gils, 2018, Arteriosclerosis, thrombosis, and vascular biology.

Peroxiredoxin 2 Deficiency Exacerbates Atherosclerosis in Apolipoprotein E–Deficient Mice

H. Jo, S. Kang, S. Rhee, 2011, Circulation research.

Endothelial UCP2 Is a Mechanosensitive Suppressor of Atherosclerosis

H. Jo, A. Xu, Xiao Lin, 2022, Circulation research.

High glucose and palmitate increases bone morphogenic protein 4 expression in human endothelial cells

H. Jo, H. Kwon, B. Cha, 2016, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

Effects of pyrrolidine dithiocarbamate on endothelial cells: protection against oxidative stress.

H. Jo, V. Darley-Usmar, D. Moellering, 1999, Free radical biology & medicine.

Shear stress regulates endothelial NO synthase (eNOS) by the protein kinase A (PKA)-dependent mechanisms

Y. Boo, H. Jo, 2002, Proceedings of the Second Joint 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society] [Engineering in Medicine and Biology.

The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for gamma-glutamylcysteine synthetase and gamma-glutamyl transpeptidase.

H. Jo, H. Forman, R. Mulcahy, 1999, FEBS letters.

Nitric oxide, free radicals and cell signalling in cardiovascular disease.

H. Jo, T. Lincoln, T. Cornwell, 1997, Biochemical Society transactions.

Novel Animal Models of Atherosclerosis

H. Jo, A. Rezvan, Sanjoli Sur, 2015 .

A role for PYK2 in ANG II-dependent regulation of the PHAS-1-eIF4E complex by multiple signaling cascades in vascular smooth muscle.

H. Jo, P. Lucchesi, P. Ročić, 2003, American journal of physiology. Cell physiology.

Targeted Intravenous Nanoparticle Delivery: Role of Flow and Endothelial Glycocalyx Integrity

R. Kumar, H. Jo, S. Sridhar, 2020, Annals of Biomedical Engineering.

Cyclic pressure and shear stress regulate matrix metalloproteinases and cathepsin activity in porcine aortic valves.

A. Yoganathan, H. Jo, M. Platt, 2006, The Journal of heart valve disease.

Emerging role of IGF-1R in stretch-induced neointimal hyperplasia in venous grafts.

H. Jo, M. Sykes, Hannah Song, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Disturbed Flow Induces Atherosclerosis by Annexin A2-Mediated Integrin Activation.

H. Jo, Catherine J. Demos, D. Williams, 2020, Circulation research.

ZBTB46 is a shear-sensitive transcription factor inhibiting endothelial cell proliferation via gene expression regulation of cell cycle proteins

H. Jo, Sandeep Kumar, He-ying Sun, 2018, Laboratory Investigation.

Is Endothelial Dysfunction a Therapeutic Target for Peripheral Artery Disease?: PRDM16 is going out on a limb.

H. Jo, Sandeep Kumar, Aitor Andueza, 2021, Circulation research.

Vascular Injury Involves the Overoxidation of Peroxiredoxin Type II and Is Recovered by the Peroxiredoxin Activity Mimetic That Induces Reendothelialization

H. Jo, S. Kang, D. Kang, 2013, Circulation.

HIF1A inhibitor PX-478 reduces pathological stretch-induced calcification and collagen turnover in aortic valve

A. Yoganathan, H. Jo, Md Tausif Salim, 2022, Frontiers in Cardiovascular Medicine.

Sox13 is a novel flow-sensitive transcription factor that prevents inflammation by repressing chemokine expression in endothelial cells

H. Jo, Yerin Kim, Sandeep Kumar, 2022, Frontiers in Cardiovascular Medicine.

Angiotensin II induces DNA damage via AT1 receptor and NADPH oxidase

H. Jo, G. Fazeli, H. Stopper, 2012 .

Angiotensin II induces DNA damage via AT 1 receptor and NADPH oxidase isoform Nox

H. Jo, G. Fazeli, H. Stopper, 2012 .

miR-214 is Stretch-Sensitive in Aortic Valve and Inhibits Aortic Valve Calcification

A. Yoganathan, R. Nerem, H. Jo, 2019, Annals of Biomedical Engineering.

Phosphatidylinositol 3-kinase gamma mediates shear stress-dependent activation of JNK in endothelial cells.

H. Jo, R. Wetzker, H. Park, 1998, The American journal of physiology.

Chronic shear induces caveolae formation and alters ERK and Akt responses in endothelial cells.

Y. Boo, H. Jo, Heonyong Park, 2003, American journal of physiology. Heart and circulatory physiology.

Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells

Jun Zhu, H. Jo, R. Brandes, 2018, Nature Communications.

Strain Magnitude-Dependent Calcific Marker Expression in Valvular and Vascular Cells

R. Nerem, H. Jo, Z. Ferdous, 2013, Cells Tissues Organs.

Piperlongumine inhibits atherosclerotic plaque formation and vascular smooth muscle cell proliferation by suppressing PDGF receptor signaling.

Young Hyun Park, H. Jo, Y. Yun, 2012, Biochemical and biophysical research communications.

Animal, in vitro, and ex vivo models of flow-dependent atherosclerosis: role of oxidative stress.

H. Jo, A. Rezvan, C. Ni, 2011, Antioxidants & redox signaling.

Mechanisms of cell signaling by nitric oxide and peroxynitrite: from mitochondria to MAP kinases.

S. Parthasarathy, H. Jo, Y. Go, 2001, Antioxidants & redox signaling.

The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches.

H. Jo, Sandeep Kumar, R. Simmons, 2016, Archives of biochemistry and biophysics.

Conditional Antisense Oligonucleotides Triggered by miRNA.

K. Salaita, H. Jo, Radhika Sharma, 2021, ACS chemical biology.

Conditional Deoxyribozyme-Nanoparticle Conjugates for miRNA-Triggered Gene Regulation.

K. Salaita, H. Jo, Aaron T. Blanchard, 2020, ACS applied materials & interfaces.

Role of flow-sensitive microRNAs in endothelial dysfunction and atherosclerosis: mechanosensitive athero-miRs.

H. Jo, Sandeep Kumar, Chan Woo Kim, 2014, Arteriosclerosis, thrombosis, and vascular biology.

Aging-regulated TUG1 is dispensable for endothelial cell function

N. Hübner, H. Jo, S. Dimmeler, 2022, bioRxiv.

Role of Noncoding RNAs in the Pathogenesis of Abdominal Aortic Aneurysm.

H. Jo, S. Dimmeler, Sandeep Kumar, 2019, Circulation research.

Endothelial Reprogramming by Disturbed Flow Revealed by Single-Cell RNA and Chromatin Accessibility Study

H. Jo, Sandeep Kumar, D. Kang, 2020, bioRxiv.

Signaling Pathways

F. Biering-Sørensen, H. Jo, J. Helgerud, 2003 .

MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells.

H. Jo, C. Ni, Haiwei Qiu, 2011, American journal of physiology. Heart and circulatory physiology.

The role of epigenetics in the endothelial cell shear stress response and atherosclerosis.

J. Dunn, H. Jo, Salim R. Thabet, 2015, The international journal of biochemistry & cell biology.

Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis.

J. Dunn, H. Jo, Salim R. Thabet, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Phosphatidylinositol 3-kinase γ mediates shear stress-dependent activation of JNK in endothelial cells.

H. Jo, R. Wetzker, Y. Go, 1998, American journal of physiology. Heart and circulatory physiology.

The role of the vascular dendritic cell network in atherosclerosis.

T. Denning, H. Jo, A. Rezvan, 2013, American journal of physiology. Cell physiology.

Anti-Inflammatory and Antiatherogenic Role of BMP Receptor II in Endothelial Cells

H. Jo, D. Weiss, K. Griendling, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Target accessibility and signal specificity in live-cell detection of BMP-4 mRNA using molecular beacons

H. Jo, G. Bao, P. Santangelo, 2008, Nucleic acids research.

Role of NADPH oxidases in disturbed flow- and BMP4- induced inflammation and atherosclerosis.

H. Jo, Hannah Song, A. Mowbray, 2006, Antioxidants & redox signaling.

Bone Morphogenic Protein-4 Induces Hypertension in Mice: Role of Noggin, Vascular NADPH Oxidases, and Impaired Vasorelaxation

D. Harrison, H. Jo, S. Dikalov, 2006, Circulation.

Deep transcriptomic profiling reveals the similarity between endothelial cells cultured under static and oscillatory shear stress conditions.

H. Jo, Y. E. Chen, F. Meng, 2016, Physiological genomics.

Caveolin‐mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo

J. Engelman, H. Jo, M. Lisanti, 1998, FEBS letters.

Mechanosensitive microRNA-181b Regulates Aortic Valve Endothelial Matrix Degradation by Targeting TIMP3

H. Jo, Sandeep Kumar, J. Heath, 2018, Cardiovascular engineering and technology.

Conserved miR-370-3p/BMP-7 axis regulates the phenotypic change of human vascular smooth muscle cells

H. Jo, Sanghyuk Lee, S. Kang, 2023, Scientific Reports.

KLF2 and KLF4 control endothelial identity and vascular integrity.

H. Jo, Sandeep Kumar, D. Kang, 2017, JCI insight.

Disturbed Flow Increases UBE2C (Ubiquitin E2 Ligase C) via Loss of miR-483-3p, Inducing Aortic Valve Calcification by the pVHL (von Hippel-Lindau Protein) and HIF-1&agr; (Hypoxia-Inducible Factor-1&agr;) Pathway in Endothelial Cells

A. Yoganathan, R. Nerem, H. Jo, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Bovine caveolin-2 cloning and effects of shear stress on its localization in bovine aortic endothelial cells.

H. Jo, Heonyong Park, N. Boyd, 2004, Endothelium : journal of endothelial cell research.

Maturing EPCs into endothelial cells: may the force be with the EPCs: focus on "Fluid shear stress induces differentiation of circulating phenotype endothelial progenitor cells".

Casey J. Ankeny, R. Nerem, H. Jo, 2012, American journal of physiology. Cell physiology.

Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation

H. Jo, Sandeep Kumar, D. Kang, 2017, Laboratory investigation; a journal of technical methods and pathology.

Compensatory Phosphorylation and Protein-Protein Interactions Revealed by Loss of Function and Gain of Function Mutants of Multiple Serine Phosphorylation Sites in Endothelial Nitric-oxide Synthase*

Hanjoong Jo, Y. Boo, H. Jo, 2003, The Journal of Biological Chemistry.

Nitric Oxide-Dependent Induction of Glutathione Synthesis through Increased Expression of γ-Glutamylcysteine Synthetase

H. Jo, H. Forman, T. Lincoln, 1998 .

HuR regulates the expression of stress-sensitive genes and mediates inflammatory response in human umbilical vein endothelial cells

H. Jo, G. Bao, W. Rhee, 2010, Proceedings of the National Academy of Sciences.

Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis.

J. Dunn, H. Jo, I. K. Jordan, 2014, The Journal of clinical investigation.

Activation of c-Jun N-Terminal Kinase and Apoptosis in Endothelial Cells Mediated by Endogenous Generation of Hydrogen Peroxide

S. Parthasarathy, H. Jo, A. Ramachandran, 2002, Biological chemistry.

Caveolin‐1 Knockout Mice Have Increased Bone Size and Stiffness

H. Jo, B. Boyan, Z. Schwartz, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Omics‐based approaches to understand mechanosensitive endothelial biology and atherosclerosis

H. Jo, Sandeep Kumar, Sanjoli Sur, 2016, Wiley interdisciplinary reviews. Systems biology and medicine.

Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis.

H. Jo, M. Hyman, S. Visovatti, 2015, The Journal of clinical investigation.

Myeloid CCN3 protects against aortic valve calcification

H. Jo, Caiwen Ou, Sandeep Kumar, 2023, Cell Communication and Signaling.

Shear Stress Stimulates Phosphorylation of Endothelial Nitric-oxide Synthase at Ser1179 by Akt-independent Mechanisms

I. Shiojima, Y. Boo, H. Jo, 2002, The Journal of Biological Chemistry.

Combined LXR and RXR Agonist Therapy Increases ABCA1 Protein Expression and Enhances ApoAI-Mediated Cholesterol Efflux in Cultured Endothelial Cells

H. Jo, Alexis D. Stamatikos, Kun Huang, 2021, Metabolites.

Atorvastatin and blood flow regulate expression of distinctive sets of genes in mouse carotid artery endothelium.

H. Jo, Sandeep Kumar, Chan Woo Kim, 2021, Current topics in membranes.

miR-214 is Stretch-Sensitive in Aortic Valve and Inhibits Aortic Valve Calcification

A. Yoganathan, R. Nerem, H. Jo, 2019, Annals of Biomedical Engineering.

Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow.

J. Visvader, H. Jo, D. Son, 2010, Blood.

NFKB1 promoter variation implicates shear-induced NOS3 gene expression and endothelial function in prehypertensives and stage I hypertensives.

S. Brant, H. Jo, Joon-Young Park, 2007, American journal of physiology. Heart and circulatory physiology.

Recent Progress in in vitro Models for Atherosclerosis Studies

H. Jo, Y. Yoon, B. Brott, 2022, Frontiers in Cardiovascular Medicine.

Optimization of isolation and functional characterization of primary murine aortic endothelial cells.

Hanjoong Jo, Jinah Hwang, H. Jo, 2003, Endothelium : journal of endothelial cell research.

Cell signaling by reactive nitrogen and oxygen species in atherosclerosis.

H. Jo, V. Darley-Usmar, J. Beckman, 2000, Free radical biology & medicine.

Biomechanical regulation of endothelial function in atherosclerosis

H. Jo, Ian A. Tamargo, Catherine J. Demos, 2020 .

Discovery of novel peptides targeting pro-atherogenic endothelium in disturbed flow regions -Targeted siRNA delivery to pro-atherogenic endothelium in vivo

H. Jo, S. Kang, Duhwan Lee, 2016, Scientific Reports.

Novel Animal Models of Atherosclerosis

H. Jo, A. Rezvan, Sanjoli Sur, 2015, Biomedical Engineering Letters.

Angiotensin II induces DNA damage via AT1 receptor and NADPH oxidase isoform Nox4.

H. Jo, G. Fazeli, H. Stopper, 2012, Mutagenesis.

Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress.

L. McIntire, H. Jo, D. Weiss, 2009, Cardiovascular research.

Expression of CYP 1 A 1 and CYP 1 B 1 in human endothelial cells : regulation by fluid shear stress

L. McIntire, H. Jo, D. Weiss, 2009 .

Preferential Activation of SMAD1/5/8 on the Fibrosa Endothelium in Calcified Human Aortic Valves - Association with Low BMP Antagonists and SMAD6

R. Nerem, H. Jo, D. Weiss, 2011, PloS one.

Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces.

H. Jo, A. Lusis, G. Dai, 2015, Circulation research.

Shear-Sensitive Genes in Aortic Valve Endothelium.

H. Jo, J. Heath, Joan Fernández Esmerats, 2016, Antioxidants & redox signaling.

An Ex Vivo Study of the Biological Properties of Porcine Aortic Valves in Response to Circumferential Cyclic Stretch

Ajit P. Yoganathan, Hanjoong Jo, Kartik Balachandran, 2006, Annals of Biomedical Engineering.

Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress.

Don P Giddens, Hanjoong Jo, Jinah Hwang, 2003, American journal of physiology. Heart and circulatory physiology.

Shear stress stimulates phosphorylation of eNOS at Ser(635) by a protein kinase A-dependent mechanism.

Y. Boo, H. Jo, B. Kemp, 2002, American journal of physiology. Heart and circulatory physiology.

Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells.

H. Jo, Z. Ungvari, A. Csiszar, 2008, American journal of physiology. Heart and circulatory physiology.

Bone Morphogenic Protein Antagonists Are Coexpressed With Bone Morphogenic Protein 4 in Endothelial Cells Exposed to Unstable Flow In Vitro in Mouse Aortas and in Human Coronary Arteries: Role of Bone Morphogenic Protein Antagonists in Inflammation and Atherosclerosis

D. Giddens, H. Jo, D. Weiss, 2007, Circulation.

Targeting mechanosensitive endothelial TXNDC5 to stabilize eNOS and reduce atherosclerosis in vivo

H. Jo, Kai-Chien Yang, Sandeep Kumar, 2022, Science advances.

by increasing NO production in response to shear stress Protein kinase B/Akt activates c-Jun NH2-terminal kinase

K. Pritchard, Y. Boo, H. Jo, 2013 .

Coordinated regulation of endothelial nitric oxide synthase activity by phosphorylation and subcellular localization.

Y. Boo, H. Jo, W. Sessa, 2006, Free radical biology & medicine.

Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase.

D. Harrison, Y. Boo, H. Jo, 2003, Free radical biology & medicine.

IκBα-dependent regulation of low-shear flow-induced NF-κB activity: role of nitric oxide

A. J. Valente, H. Jo, S. Mohan, 2003 .

- dependent regulation of low-shear flow-induced NF-B activity : role of nitric oxide

A. J. Valente, H. Jo, S. Mohan, 2003 .

Protein kinase B/Akt activates c-Jun NH(2)-terminal kinase by increasing NO production in response to shear stress.

K. Pritchard, Y. Boo, H. Jo, 2001, Journal of applied physiology.

Disturbed flow induces systemic changes in metabolites in mouse plasma: a metabolomics study using ApoE⁻/⁻ mice with partial carotid ligation.

Dean P. Jones, A. Quyyumi, H. Jo, 2015, American journal of physiology. Regulatory, integrative and comparative physiology.

The Role of Mechanical Stimulation in Recovery of Bone Loss—High versus Low Magnitude and Frequency of Force

Hanjoong Jo, H. Jo, Mamta Patel Nagaraja, 2014, Life.

Vascular Proteomics Reveal Novel Proteins Involved in SMC Phenotypic Change: OLR1 as a SMC Receptor Regulating Proliferation and Inflammatory Response

Eun Chun Han, Chulhee Choi, D. Hwang, 2015, PloS one.

The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for γ‐glutamylcysteine synthetase and γ‐glutamyl transpeptidase

H. Jo, H. Forman, R. Mulcahy, 1999 .

Role of Biomechanical Stress and Mechanosensitive miRNAs in Calcific Aortic Valve Disease

H. Jo, Nicolas Villa-Roel, Kitae Ryu, 2020 .

The Effects of Combined Cyclic Stretch and Pressure on the Aortic Valve Interstitial Cell Phenotype

Patrick Thayer, Ajit P. Yoganathan, Hanjoong Jo, 2011, Annals of Biomedical Engineering.

The bone morphogenic protein inhibitor, noggin, reduces glycemia and vascular inflammation in db/db mice.

H. Jo, K. Griendling, B. Lassègue, 2013, American journal of physiology. Heart and circulatory physiology.

NAD(P)H Oxidase-derived Hydrogen Peroxide Mediates Endothelial Nitric Oxide Production in Response to Angiotensin II*

D. Harrison, S. Holland, H. Jo, 2002, The Journal of Biological Chemistry.

Differences in valvular and vascular cell responses to strain in osteogenic media.

Robert M Nerem, Hanjoong Jo, R. Nerem, 2011, Biomaterials.

Shear stress and plaque development

Habib Samady, Jin Suo, Arshed A Quyyumi, 2010, Expert review of cardiovascular therapy.

Mechanical Activation of Hypoxia-Inducible Factor 1 alpha Drives Endothelial Dysfunction at Atheroprone Sites

H. Jo, A. Schober, C. Weber, 2022 .

Laminar Shear Stress Up-regulates Peroxiredoxins (PRX) in Endothelial Cells

H. Jo, S. Kang, S. Rhee, 2008, Journal of Biological Chemistry.

Disturbed Flow Promotes Arterial Stiffening Through Thrombospondin-1

H. Jo, L. Timmins, Haiyan Li, 2017, Circulation.

Laminar shear stress upregulates endothelial Ca²⁺-activated K⁺ channels KCa2.3 and KCa3.1 via a Ca²⁺/calmodulin-dependent protein kinase kinase/Akt/p300 cascade.

H. Jo, H. Miura, V. Lemaître, 2013, American journal of physiology. Heart and circulatory physiology.

Identification of mechanosensitive genes in osteoblasts by comparative microarray studies using the rotating wall vessel and the random positioning machine

Diana Risin, Hanjoong Jo, H. Jo, 2007, Journal of cellular biochemistry.

Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes.

D. Harrison, H. Jo, K. Griendling, 2007, American journal of physiology. Heart and circulatory physiology.

Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation.

H. Jo, K. Griendling, B. Lassègue, 2021, Cardiovascular research.

Fluid Mechanics, Arterial Disease, and Gene Expression.

Jessilyn Dunn, Hanjoong Jo, John M Tarbell, 2014, Annual review of fluid mechanics.

Discovery of Side- and Shear-Dependent miRNAs and mRNAs in Human Aortic Valvular Endothelial Cells

R. Nerem, H. Jo, Randall F. Ankeny, 2011 .

Design of an ex vivo culture system to investigate the effects of shear stress on cardiovascular tissue.

Ajit P Yoganathan, Muralidhar Padala, Hanjoong Jo, 2008, Journal of biomechanical engineering.

Laminar Shear Stress Inhibits Cathepsin L Activity in Endothelial Cells

H. Jo, M. Platt, Randall F. Ankeny, 2006 .

Intimal cushions and endothelial nuclear elongation around mouse aortic branches and their spatial correspondence with patterns of lipid deposition.

H. Jo, P. Weinberg, C. Ni, 2010, American journal of physiology. Heart and circulatory physiology.

The flagellin-TLR5-Nox4 axis promotes the migration of smooth muscle cells in atherosclerosis

H. Jo, Jinoh Kim, D. Kang, 2019, Experimental & Molecular Medicine.

Delivery of Anti‐microRNA‐712 to Inflamed Endothelial Cells Using Poly(β‐amino ester) Nanoparticles Conjugated with VCAM‐1 Targeting Peptide

H. Jo, Ian A. Tamargo, V. Ramos, 2021, Advanced healthcare materials.

Evidence for peroxynitrite as a signaling molecule in flow-dependent activation of c-Jun NH2-terminal kinase.

H. Jo, Y. Go, M. Maland, 1999, American journal of physiology. Heart and circulatory physiology.

Dynamic Immune Cell Accumulation During Flow-Induced Atherogenesis in Mouse Carotid Artery: An Expanded Flow Cytometry Method

Melissa L. Kemp, H. Jo, D. Son, 2012, Arteriosclerosis, thrombosis, and vascular biology.

The interplay of nitric oxide and peroxynitrite with signal transduction pathways: implications for disease.

S. Matalon, H. Jo, T. Lincoln, 1997, Seminars in perinatology.

Expression of cathepsin K is regulated by shear stress in cultured endothelial cells and is increased in endothelium in human atherosclerosis.

H. Jo, D. Weiss, M. Platt, 2007, American journal of physiology. Heart and circulatory physiology.

Simulated microgravity using the Random Positioning Machine inhibits differentiation and alters gene expression profiles of 2T3 preosteoblasts.

Min Xu, Hanjoong Jo, May D. Wang, 2005, American journal of physiology. Cell physiology.

3D Imaging and Quantitative Analysis of Vascular Networks: A Comparison of Ultramicroscopy and Micro-Computed Tomography

Michael Salamon, Hanjoong Jo, Christoph Schürmann, 2018, Theranostics.

Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting

H. Jo, K. Griendling, B. Lassègue, 2021, bioRxiv.

A model of disturbed flow-induced atherosclerosis in mouse carotid artery by partial ligation and a simple method of RNA isolation from carotid endothelium.

D. Giddens, D. Harrison, H. Jo, 2010, Journal of visualized experiments : JoVE.

Differences : Influence of Shear Stress Transcriptional Profiles of Valvular and Vascular Endothelial Cells Reveal Phenotypic

R. Nerem, H. Jo, J. Butcher, 2005 .

Multifunctional Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE–/– Mice

H. Jo, D. Son, Sandeep Kumar, 2015, ACS nano.

Tetrahydrobiopterin deficiency and Nitric Oxide Synthase uncoupling contribute to atherosclerosis induced by disturbed flow

D. Harrison, H. Jo, A. Rezvan, 2011, Arteriosclerosis, thrombosis, and vascular biology.

Arginine Dysregulation and Myocardial Dysfunction in a Mouse Model and Children with Chronic Kidney Disease

H. Jo, M. Kelleman, L. Brown, 2023, Nutrients.

Low oscillatory shear stress regulates Weibel-Palade body size and vWF release

H. Jo, D. Beech, L. McKeown, 2023, bioRxiv.

Focal Adhesion Kinase Activity and Localization is Critical for TNF-α-Induced Nuclear Factor-κB Activation

H. Jo, S. Lim, Kyuho Jeong, 2021, Inflammation.

Flow-induced reprogramming of endothelial cells in atherosclerosis

H. Jo, Yerin Kim, Ian A. Tamargo, 2023, Nature Reviews Cardiology.

Delivery of siRNA to Endothelial Cells In Vivo Using Lysine/Histidine Oligopeptide-Modified Poly(β-amino ester) Nanoparticles

H. Jo, V. Ramos, S. Borrós, 2021, Cardiovascular Engineering and Technology.

Hypoxia inducible factor 1α inhibitor PX-478 reduces atherosclerosis in mice.

H. Jo, Sandeep Kumar, D. Kang, 2022, Atherosclerosis.

Caveolin-1 is transiently dephosphorylated by shear stress-activated protein tyrosine phosphatase mu.

H. Jo, Heonyong Park, Jaeyoung Shin, 2006, Biochemical and biophysical research communications.

Ascorbic acid synthesis due to L-gulono-1,4-lactone oxidase expression enhances NO production in endothelial cells.

Y. Boo, H. Jo, Hyo Jung Kim, 2006, Biochemical and biophysical research communications.

[52] In vitro system to study role of blood flow on nitric oxide production and cell signaling in endothelial cells

H. Jo, Y. Go, M. Maland, 1999 .

Laminar shear stress inhibits lipid peroxidation induced by high glucose plus arachidonic acid in endothelial cells.

Y. Boo, H. Jo, Heonyong Park, 2008, American journal of physiology. Heart and circulatory physiology.

Targeted Delivery of Anti‐miR‐712 by VCAM1‐Binding Au Nanospheres for Atherosclerosis Therapy

Younan Xia, H. Jo, Bo Pang, 2016 .

in human atherosclerosis cultured endothelial cells and is increased in endothelium Expression of cathepsin K is regulated by shear stress in

H. Jo, D. Weiss, M. Platt, 2016 .

Serum BMP-4 levels in relation to arterial stiffness and carotid atherosclerosis in patients with Type 2 diabetes.

H. Jo, H. Kwon, B. Cha, 2011, Biomarkers in medicine.

The Impact of MiR-33a-5p Inhibition in Pro-Inflammatory Endothelial Cells

H. Jo, Lucia Vojtech, Jessica Larsen, 2023, Diseases.

Mechanosensitive microRNA-181b Regulates Aortic Valve Endothelial Matrix Degradation by Targeting TIMP3

H. Jo, Sandeep Kumar, J. Heath, 2017, Cardiovascular Engineering and Technology.

The effect of varying albumin concentration and hydrostatic pressure on hydraulic conductivity and albumin permeability of cultured endothelial monolayers.

J. Tarbell, H. Jo, T. M. Hollis, 1991, Microvascular research.

Constructing Lipoparticles Capable of Endothelial Cell-Derived Exosome-Mediated Delivery of Anti-miR-33a-5p to Cultured Macrophages

H. Jo, N. Vyavahare, Lucia Vojtech, 2023, Current issues in molecular biology.

Cardiovascular-Renal Mechanisms in Health and Disease Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes

A. San, D. Harrison, H. Jo, 2007 .

An improved method to measure nitrate/nitrite with an NO-selective electrochemical sensor.

Y. Boo, H. Jo, S. Tressel, 2007, Nitric oxide : biology and chemistry.

IkappaBalpha-dependent regulation of low-shear flow-induced NF-kappa B activity: role of nitric oxide.

A. J. Valente, H. Jo, S. Mohan, 2003, American journal of physiology. Cell physiology.

Endothelial CCRL2 induced by disturbed flow promotes atherosclerosis via chemerin-dependent β2 integrin activation in monocytes.

H. Jo, B. Zabel, Chao-jun Tang, 2023, Cardiovascular research.

Deletion of NoxO1 limits atherosclerosis development in female mice

Marcel H. Schulz, H. Jo, R. Brandes, 2020, Redox biology.

Mechano-Sensitive PPAP 2 B Regulates Endothelial Responses to Athero-Relevant Hemodynamic Forces

H. Jo, A. Lusis, G. Dai, 2015 .

Label‐free atherosclerosis diagnosis through a blood drop of apolipoprotein E knockout mouse model using surface‐enhanced Raman spectroscopy validated by machine learning algorithm

H. Jo, J. Song, Soo-Jin Kang, 2023, Bioengineering & translational medicine.

Laminar shear stress inhibits cathepsin L activity in endothelial cells (EC)

H. Jo, M. Platt, Debra A. Smith, 2006, Arteriosclerosis, thrombosis, and vascular biology.

Biomechanical factors in atherosclerosis: mechanisms and clinical implications.

R. Virmani, H. Jo, R. Krams, 2014, European heart journal.

Hemodynamic Features in Stenosed Coronary Arteries: CFD Analysis Based on Histological Images

Mahsa Dabagh, Payman Jalali, Stephen White, 2013, J. Appl. Math..

Elevated cyclic stretch alters matrix remodeling in aortic valve cusps: implications for degenerative aortic valve disease.

A. Yoganathan, H. Jo, Kartik Balachandran, 2009, American journal of physiology. Heart and circulatory physiology.

Identification of side- and shear-dependent microRNAs regulating porcine aortic valve pathogenesis

Casey J. Ankeny, A. Yoganathan, R. Nerem, 2016, Scientific Reports.

Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow.

J. Visvader, H. Jo, D. Son, 2010, Blood.

The Effects of Combined Cyclic Stretch and Pressure on the Aortic Valve Interstitial Cell Phenotype

A. Yoganathan, H. Jo, C. Yap, 2011, Annals of Biomedical Engineering.

The role of endothelial mechanosensitive genes in atherosclerosis and omics approaches.

H. Jo, Sandeep Kumar, R. Simmons, 2016, Archives of biochemistry and biophysics.

The role of epigenetics in the endothelial cell shear stress response and atherosclerosis.

J. Dunn, H. Jo, Salim R. Thabet, 2015, The international journal of biochemistry & cell biology.

Flow-dependent expression of ectonucleotide tri(di)phosphohydrolase-1 and suppression of atherosclerosis.

H. Jo, S. Visovatti, Hui Liao, 2015, The Journal of clinical investigation.

Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces.

H. Jo, A. Lusis, G. Dai, 2015, Circulation research.

Development of immortalized mouse aortic endothelial cell lines

Casey J. Ankeny, H. Jo, Sandeep Kumar, 2014, Vascular cell.

NITRIC OXIDE, FREE RADICALS AND CELL SIGNALLING IN CARDIOVASCULAR DISEASE

H. Jo, T. Cornwell, V. Darley-Usmar, 1997 .

Redox going with vascular shear stress.

H. Jo, N. Noguchi, 2011, Antioxidants & redox signaling.

Redox-sensitive Akt and Src regulate coronary collateral growth in metabolic syndrome.

H. Jo, B. Potter, Patricia C Villalta, 2009, American journal of physiology. Heart and circulatory physiology.

Prevention of Abdominal Aortic Aneurysm by Anti–MicroRNA-712 or Anti–MicroRNA-205 in Angiotensin II–Infused Mice

H. Jo, K. Griendling, D. Son, 2014, Arteriosclerosis, thrombosis, and vascular biology.

Disturbed Flow Promotes Arterial Stiffening Through Thrombospondin-1

H. Jo, L. Timmins, Haiyan Li, 2017, Circulation.

X-linked inhibitor of apoptosis protein controls alpha5-integrin-mediated cell adhesion and migration.

Y. Boo, H. Jo, S. Chi, 2010, American journal of physiology. Heart and circulatory physiology.

Mechanical Activation of Hypoxia-Inducible Factor 1α Drives Endothelial Dysfunction at Atheroprone Sites

H. Jo, A. Schober, C. Weber, 2017, Arteriosclerosis, thrombosis, and vascular biology.

Aortic Valve: Mechanical Environment and Mechanobiology

A. Yoganathan, H. Jo, Sivakkumar Arjunon, 2013, Annals of Biomedical Engineering.

Piperlongumine inhibits atherosclerotic plaque formation and vascular smooth muscle cell proliferation by suppressing PDGF receptor signaling.

Young Hyun Park, H. Jo, Y. Yun, 2012, Biochemical and biophysical research communications.

Dynamic Immune Cell Accumulation During Flow-Induced Atherogenesis in Mouse Carotid Artery: An Expanded Flow Cytometry Method

Melissa L. Kemp, H. Jo, D. Son, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Stress Hormones

H. Jo, J. Helgerud, A. Hackney, 2020, Encyclopedia of Evolutionary Psychological Science.

Nuclear FAK in endothelium: An intrinsic inhibitor of NF-κB activation in atherosclerosis.

H. Jo, S. Lim, Kyuho Jeong, 2023, Atherosclerosis.

Hydraulic Conductivity and Shear Dependent Albumin Permeability of Cultured Endothelial Cell Monolayers

J. Tarbell, H. Jo, T. M. Hollis, 1990 .

Oscillatory Shear Stress Stimulates Endothelial Production of \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathrm{O}_{2}^{-}\) \end{document} from p47phox-dependent NAD(P)H Oxidases, Le

D. Giddens, D. Harrison, S. Holland, 2003, Journal of Biological Chemistry.