J. Welsh

发表

Human mammary epithelial cells express CYP27B1 and are growth inhibited by 25-hydroxyvitamin D-3, the major circulating form of vitamin D-3.

Carly M. Kemmis, Sally M. Salvador, Kelly Smith, 2006, The Journal of nutrition.

Self‐Assembled Poly(butadiene)‐b‐poly(ethylene oxide) Polymersomes as Paclitaxel Carriers

J. Welsh, Shuliang Li, B. Byrne, 2007, Biotechnology progress.

Dissociation of vitamin D3 and anti-estrogen mediated growth regulation in MCF-7 breast cancer cells

J. Welsh, L. Flanagan, E. Nolan, 1998, Molecular and Cellular Biochemistry.

Potent Antiproliferative Effects of 25‐Hydroxy‐16‐ene‐23‐yne‐vitamin D3 That Resists the Catalytic Activity of Both CYP27B1 and CYP24A1

J. Welsh, M. Uskoković, T. Itoh, 2014, Journal of cellular biochemistry.

Transcriptional effects of 1,25 dihydroxyvitamin D3 physiological and supra-physiological concentrations in breast cancer organotypic culture

J. Welsh, M. Brentani, P. D. del Valle, 2013, BMC Cancer.

The molecular basis of vitamin D receptor and beta-catenin crossregulation.

J. Welsh, S. Byers, S. Dakshanamurthy, 2006, Molecular cell.

Active cell death in hormone-dependent tissues

J. Welsh, J. Lakins, M. Tenniswood, 1992, Cancer and Metastasis Reviews.

A crucial role for the vitamin D receptor in experimental inflammatory bowel diseases.

J. Welsh, T. Wynn, M. Cantorna, 2003, Molecular endocrinology.

Modeling vitamin D actions in triple negative/basal-like breast cancer

J. Welsh, E. LaPorta, 2014, The Journal of Steroid Biochemistry and Molecular Biology.

Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis.

J. Sundberg, J. Welsh, G. Zinser, 2002, Carcinogenesis.

Vitamin D regulation of HAS2, hyaluronan synthesis and metabolism in triple negative breast cancer cells

J. Welsh, S. Balinth, D. Grebenc, 2020, The Journal of Steroid Biochemistry and Molecular Biology.

Activation of protein kinase C modulates dihydroxycholecalciferol synthesis in rat renal tubules.

J. Welsh, D. Franks, V. Weaver, 1992, Cellular signalling.

Altered thioredoxin subcellular localization and redox status in MCF-7 cells following 1,25-dihydroxyvitamin D3 treatment

J. Welsh, B. Byrne, Belinda M. Byrne, 2005, The Journal of Steroid Biochemistry and Molecular Biology.

Phytoestrogen regulation of a Vitamin D3 receptor promoter and 1,25-dihydroxyvitamin D3 actions in human breast cancer cells

J. Welsh, Jennifer A. Wietzke, 2003, The Journal of Steroid Biochemistry and Molecular Biology.

Adipose-specific Vdr deletion alters body fat and enhances mammary epithelial density

J. Welsh, J. D'angelo, Donald G Matthews, 2016, The Journal of Steroid Biochemistry and Molecular Biology.

Role of apoptosis in the growth inhibitory effects of vitamin D in MCF-7 cells.

J. Welsh, M. Tenniswood, C. Narvaez, 1995, Advances in experimental medicine and biology.

Identification of a hormone-responsive promoter immediately upstream of exon 1c in the human vitamin D receptor gene.

J. Welsh, M. Tenniswood, L. Flanagan, 2000, Endocrinology.

Protein kinase C isozymes and substrates in mammary carcinogenesis

J. Welsh, S. Kiley, S. Jaken, 1996, Journal of Mammary Gland Biology and Neoplasia.

1,25-Dihydroxyvitamin D3 induces morphological and biochemical markers of apoptosis in MCF-7 breast cancer cells

J. Welsh, M. Tenniswood, C. Narvaez, 1996, The Journal of Steroid Biochemistry and Molecular Biology.

Vitamin D receptor-dependent inhibition of mammary tumor growth by EB1089 and ultraviolet radiation in vivo.

J. Welsh, Meggan E. Valrance, Andrea Brunet, 2007, Endocrinology.

Vitamin D-regulated pathways: impact on cell proliferation, differentiation, and apoptosis.

J. Welsh, J. Zempleni, K. Dakshinamurti, 2005 .

Effect of the Vitamin D Receptor on Bone Geometry and Strength During Gestation and Lactation in Mice

G. Niebur, J. Welsh, C. Korecki, 2009, Calcified Tissue International.

Anti-proliferative action of vitamin D in MCF7 is still active after siRNA-VDR knock-down

J. L. Costa, M. A. van de Wiel, B. Ylstra, 2009, BMC Genomics.

Vitamin D receptor (VDR) ablation alters carcinogen-induced tumorigenesis in mammary gland, epidermis and lymphoid tissues

J. Welsh, M. Suckow, G. Zinser, 2005, The Journal of Steroid Biochemistry and Molecular Biology.

1,25 Dihydroxyvitamin D3: Coordinate Regulator of Active Cell Death and Proliferation in MCF-7 Breast Cancer Cells

J. Welsh, M. Simboli-Campbell, 1995 .

Buthionine Sulfoximine and 1,25-Dihydroxyvitamin D Induce Apoptosis in Breast Cancer Cells via Induction of Reactive Oxygen Species

J. Welsh, V. Rodriguez, N. G. Tolosa de Talamoni, 2012, Cancer investigation.

Identification of novel mediators of Vitamin D signaling and 1,25(OH)2D3 resistance in mammary cells

J. Welsh, B. Byrne, Belinda M. Byrne, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

Tumor progression in the LPB-Tag transgenic model of prostate cancer is altered by vitamin D receptor and serum testosterone status

J. Welsh, M. Tenniswood, Wei-lin Wang, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

The role of vitamin D3 and antiestrogens in modulating apoptosis of breast cancer cells and tumors.

J. Welsh, L. Flanagan, E. Nolan, 1998, Sub-cellular biochemistry.

Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogens.

J. Welsh, 1994, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Vitamin D receptors and compensatory tissue growth in spontaneously diabetic BB rats.

J. Welsh, S. Christakos, M. Bruns, 1991, Annals of nutrition & metabolism.

1,24(S)-dihydroxyvitamin D2, an endogenous vitamin D2 metabolite, inhibits growth of breast cancer cells and tumors.

R. Mazess, J. Welsh, S. Strugnell, 2005, Anticancer research.

OR SELL ANY PATENTED INVENTION THAT MAY RELATE TO THEM . LIMITED RIGHTS LEGEND Award Number : DAMD 1797-1-7183 Organization : The University of Notre

J. Welsh, C. Narvaez, 2022 .

VDR in salivary gland homeostasis and cancer

J. Welsh, K. DeSantis, Noor M. Kotb, 2020, The Journal of Steroid Biochemistry and Molecular Biology.

Efficacy of Vitamin D compounds to modulate estrogen receptor negative breast cancer growth and invasion

J. Welsh, K. Packman, M. Tenniswood, 2003, The Journal of Steroid Biochemistry and Molecular Biology.

1,25(OH)2D3 increases membrane associated protein kinase C in MDBK cells.

J. Welsh, D. Franks, M. Simboli-Campbell, 1992, Cellular signalling.

The Role of Vitamin D and Vitamin D Receptor in Immunity to Leishmania major Infection

J. Welsh, Jun Fu, M. Cantorna, 2011, Journal of parasitology research.

Human breast tumor slices: A model for identification of vitamin D regulated genes in the tumor microenvironment

J. Welsh, M. Brentani, M. Katayama, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

Stable expression of human VDR in murine VDR‐null cells recapitulates vitamin D mediated anti‐cancer signaling

J. Welsh, E. LaPorta, Meggan E. Keith, 2014, Molecular carcinogenesis.

Dietary calcium does not affect prostate tumor progression in LPB-Tag transgenic mice

J. Welsh, M. Tenniswood, G. Zinser, 2007, The Journal of Steroid Biochemistry and Molecular Biology.

A non-calcemic sulfone version of the vitamin D(3) analogue seocalcitol (EB 1089): chemical synthesis, biological evaluation and potency enhancement of the anticancer drug adriamycin.

J. Welsh, D. Gewirtz, T. Kensler, 2001, Bioorganic & medicinal chemistry.

Effect of Vitamin D3 receptor ablation on murine mammary gland development and tumorigenesis

J. Welsh, G. Zinser, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

New insights into vitamin K biology with relevance to cancer.

J. Welsh, Min-Ji Bak, C. Narvaez, 2022, Trends in molecular medicine.

Characterization of a vitamin D3-resistant MCF-7 cell line.

J. Welsh, K. Vanweelden, C. Narvaez, 1996, Endocrinology.

TPA decreases 1,25(OH)2D3 binding and calbindin D-28K in renal (MDBK) cells

J. Welsh, D. Franks, A. Gagnon, 1992, Molecular and Cellular Endocrinology.

Induction of apoptosis by 1,25-dihydroxyvitamin D3 in MCF-7 Vitamin D3-resistant variant can be sensitized by TPA

J. Welsh, B. Byrne, Meggan E. Valrance, 2003, The Journal of Steroid Biochemistry and Molecular Biology.

Vitamin D and breast cancer: Past and present

J. Welsh, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

Antiproliferative action of menadione and 1,25(OH)2D3 on breast cancer cells

J. Welsh, A. Marchionatti, G. Picotto, 2009, The Journal of Steroid Biochemistry and Molecular Biology.

Retinoids modulate expression of the endocytic partners megalin, cubilin, and disabled-2 and uptake of vitamin D-binding protein in human mammary cells.

J. Welsh, M. Rowling, Timothy M. Chlon, 2008, The Journal of nutrition.

The Molecular Basis of Vitamin D Receptor and β-Catenin Crossregulation

J. Welsh, S. Byers, S. Dakshanamurthy, 2006 .

The regulation of adenylate cyclase in liver membranes of lean and obese mice

J. Welsh, N. Bégin-Heick, 1988, Molecular and Cellular Endocrinology.

Effects of 1α,25 dihydroxyvitamin D3 and testosterone on miRNA and mRNA expression in LNCaP cells

J. Welsh, S. Chittur, M. Tenniswood, 2011, Molecular Cancer.

Vitamin D and prevention of breast cancer

J. Welsh, 2007, Acta Pharmacologica Sinica.

Vitamin D(3) receptor ablation alters mammary gland morphogenesis.

J. Welsh, K. Packman, G. Zinser, 2002, Development.

Role of Mitochondria and Caspases in Vitamin D-mediated Apoptosis of MCF-7 Breast Cancer Cells*

J. Welsh, C. Narvaez, 2001, The Journal of Biological Chemistry.

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer

J. Welsh, E. LaPorta, C. Narvaez, 2020, Oncotarget.

Protective role of vitamin D signaling in skin cancer formation

J. Welsh, J. Cleaver, D. Bikle, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

The Vitamin D Signaling Pathway in Mammary Gland and Breast Cancer

J. Welsh, G. Zinser, C. Narvaez, 2011 .

Crosstalk between the vitamin D receptor (VDR) and miR-214 in regulating SuFu, a hedgehog pathway inhibitor in breast cancer cells.

M. Cleary, J. Welsh, R. Mehta, 2016, Experimental cell research.

Vitamin D receptor status alters mammary gland morphology and tumorigenesis in MMTV-neu mice.

J. Welsh, G. Zinser, 2004, Carcinogenesis.

Induction of STEAP4 correlates with 1,25‐dihydroxyvitamin D3 stimulation of adipogenesis in mesenchymal progenitor cells derived from human adipose tissue

J. Welsh, S. Chittur, J. Brunton, 2013, Journal of cellular physiology.

Function of the vitamin D endocrine system in mammary gland and breast cancer

J. Welsh, 2017, Molecular and Cellular Endocrinology.

Modeling Breast Cancer in Animals—Considerations for Prevention and Treatment Studies

J. Welsh, 2017 .

Comparative regulation of gene expression by 1,25-dihydroxyvitamin D3 in cells derived from normal mammary tissue and breast cancer

J. Welsh, Samantha Robilotto, Sarah G. Beaudin, 2015, The Journal of Steroid Biochemistry and Molecular Biology.

Animal Models for Studying Prevention and Treatment of Breast Cancer

J. Welsh, 2013 .

Differential effects of 1,25-dihydroxyvitamin D3 and tetradecanoylphorbol acetate on cell cycle and apoptosis of MCF-7 cells and a vitamin D3-resistant variant.

J. Welsh, C. Narvaez, 1997, Endocrinology.

Genomic vitamin D signaling in breast cancer: Insights from animal models and human cells

J. Welsh, E. LaPorta, G. Zinser, 2010, The Journal of Steroid Biochemistry and Molecular Biology.

1,25-Dihydroxyvitamin D3 modulates lipid metabolism in prostate cancer cells through miRNA mediated regulation of PPARA

J. Welsh, M. Tenniswood, Wei-lin Wang, 2013, The Journal of Steroid Biochemistry and Molecular Biology.

Control of TCF-4 Expression by VDR and Vitamin D in the Mouse Mammary Gland and Colorectal Cancer Cell Lines

J. Welsh, S. Byers, Marcy E. Beildeck, 2009, PloS one.

Over-expression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor null mice

J. Welsh, P. Elias, D. Bikle, 2011 .

1,25-Dihydroxyvitamin D Regulation of Glutamine Synthetase and Glutamine Metabolism in Human Mammary Epithelial Cells

J. Welsh, Sarah G. Beaudin, 2017, Endocrinology.

Vitamin D Actions in Mammary Gland and Breast Cancer

J. Welsh, 2011 .

Mammary epithelial cell transformation is associated with deregulation of the vitamin D pathway

Carly M. Kemmis, J. Welsh, Carly M. Kemmis, 2008, Journal of cellular biochemistry.

Regulation of the human Vitamin D3 receptor promoter in breast cancer cells is mediated through Sp1 sites

J. Welsh, J. Schneider, Jennifer A. Wietzke, 2005, Molecular and Cellular Endocrinology.

Gene Signatures of 1,25‐Dihydroxyvitamin D3 Exposure in Normal and Transformed Mammary Cells

J. Welsh, C. Narvaez, K. Simmons, 2015, Journal of Cellular Biochemistry.

CHAPTER 31 – Calcium and Vitamin D

J. Welsh, 2006 .

Comparative effects of 1,25(OH)2D3 and EB1089 on cell cycle kinetics and apoptosis in MCF-7 breast cancer cells

J. Welsh, K. Vanweelden, M. Tenniswood, 2004, Breast Cancer Research and Treatment.

Functions of 1α,25-dihydroxyvitamin D3 in mammary gland: from normal development to breast cancer

J. Welsh, G. Zinser, C. Narvaez, 2001, Steroids.

Apoptotic regression of MCF-7 xenografts in nude mice treated with the vitamin D3 analog, EB1089.

J. Welsh, L. Binderup, M. Tenniswood, 1998, Endocrinology.

Vitamin D compounds as potential therapeutics for estrogen-independent breast cancer.

J. Welsh, 1997, Nutrition (Burbank, Los Angeles County, Calif.).

Vitamin D and Breast Cancer: Mechanistic Update

J. Welsh, 2021, JBMR plus.

J. Welsh, S. Waltz, G. Zinser, 2011, PloS one.

Breast cancer cell regulation by high-dose Vitamin D compounds in the absence of nuclear Vitamin D receptor

J. Welsh, Meggan E. Valrance, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Vitamin D-3 receptor as a target for breast cancer prevention.

Kelly Smith, J. Welsh, B. Byrne, 2003, The Journal of nutrition.

Nutritional Genomics in Cancer Processes Vitamin D-3 Receptor as a Target for Breast Cancer Prevention 1 , 2

Kelly Smith, J. Welsh, B. Byrne, 2003 .

Impact of the Vitamin D3 receptor on growth-regulatory pathways in mammary gland and breast cancer

J. Welsh, B. Byrne, G. Zinser, 2002, The Journal of Steroid Biochemistry and Molecular Biology.

SUM-159PT cells: a novel estrogen independent human breast cancer model system

Stephen P. Ethier, J. Welsh, S. Ethier, 1999, Breast Cancer Research and Treatment.

Vitamin D, Vitamin D Receptor, and Adipose Tissue: Focus on Cellular Mechanisms

J. Welsh, C. Narvaez, Donald G Matthews, 2018 .

Vitamin D and testosterone co-ordinately modulate intracellular zinc levels and energy metabolism in prostate cancer cells

J. Welsh, Wei-lin Wang, M. Tenniswood, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

Cellular and molecular effects of vitamin D on carcinogenesis.

J. Welsh, 2012, Archives of biochemistry and biophysics.

Megalin-mediated endocytosis of vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells.

Carly M. Kemmis, J. Welsh, M. Rowling, 2006, The Journal of nutrition.

Vitamin K2 enhances the tumor suppressive effects of 1,25(OH)2D3 in triple negative breast cancer cells

J. Welsh, Min-Ji Bak, C. Narvaez, 2023, The Journal of Steroid Biochemistry and Molecular Biology.

Assessment of the proliferative capacity of the flavanones 8-prenylnaringenin, 6-(1.1-dimethylallyl)naringenin and naringenin in MCF-7 cells and the rat mammary gland

J. Welsh, G. Vollmer, K. Kräker, 2014, Molecular and Cellular Endocrinology.

Induction of calbindin D-28K in Madin-Darby bovine kidney cells by 1,25(OH)2D3.

J. Welsh, A. Gagnon, M. Simboli-Campbell, 1994, Kidney international.

Effects of the aryl hydrocarbon receptor agonist 3-methylcholanthrene on the 17β-estradiol regulated mRNA transcriptome of the rat uterus

J. Welsh, S. Chittur, G. Vollmer, 2017, The Journal of Steroid Biochemistry and Molecular Biology.

Vitamin D and breast cancer: insights from animal models.

J. Welsh, 2004, The American journal of clinical nutrition.

Lean phenotype and resistance to diet-induced obesity in vitamin D receptor knockout mice correlates with induction of uncoupling protein-1 in white adipose tissue.

Michelle Chan, J. Welsh, JoEllen Welsh, 2009, Endocrinology.

Targets of Vitamin D Receptor Signaling in the Mammary Gland

J. Welsh, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Functions of 1alpha,25-dihydroxyvitamin D(3) in mammary gland: from normal development to breast cancer.

J. Welsh, G. Zinser, C. Narvaez, 2001, Steroids.

Vitamin D metabolism in mammary gland and breast cancer

J. Welsh, 2011, Molecular and Cellular Endocrinology.

The impact of vitamin D in breast cancer: genomics, pathways, metabolism

J. Welsh, E. LaPorta, C. Narvaez, 2014, Front. Physiol..

Characterization of mammary tumor cell lines from wild type and vitamin D3 receptor knockout mice

J. Welsh, G. Zinser, Kevin G McEleney, 2003, Molecular and Cellular Endocrinology.

Calcium, vitamin D and the vitamin D receptor: impact on prostate and breast cancer in preclinical models.

J. Welsh, M. Tenniswood, G. Zinser, 2007, Nutrition reviews.

Accelerated mammary gland development during pregnancy and delayed postlactational involution in vitamin D3 receptor null mice.

J. Welsh, G. Zinser, 2004, Molecular endocrinology.

1,25-Dihydroxyvitamin D3 translocates protein kinase C beta to nucleus and enhances plasma membrane association of protein kinase C alpha in renal epithelial cells.

J. Welsh, D. Franks, A. Gagnon, 1994, The Journal of biological chemistry.

Vitamin D and cancer: Integration of cellular biology, molecular mechanisms and animal models

J. Welsh, 2012, Scandinavian journal of clinical and laboratory investigation. Supplementum.

1,25-Dihydroxyvitamin D induces the glutamate transporter SLC1A1 and alters glutamate handling in non-transformed mammary cells

J. Welsh, Sarah G. Beaudin, 2016, Molecular and Cellular Endocrinology.

Combined treatment of menadione and calcitriol increases the antiproliferative effect by promoting oxidative/nitrosative stress, mitochondrial dysfunction, and autophagy in breast cancer MCF-7 cells.

J. Welsh, V. Rodriguez, N. G. Tolosa de Talamoni, 2020, Canadian journal of physiology and pharmacology.

Vitamin D Receptor and p21/WAF1 Are Targets of Genistein and 1,25-Dihydroxyvitamin D3 in Human Prostate Cancer Cells

J. Welsh, S. Cramer, C. Koumenis, 2004, Cancer Research.

Vitamin D Receptor and p 21 / WAF 1 Are Targets of Genistein and 1 , 25-Dihydroxyvitamin D 3 in Human Prostate Cancer Cells

J. Welsh, S. Cramer, C. Koumenis, 2004 .

Dissociation of growth arrest and CYP24 induction by VDR ligands in mammary tumor cells

J. Welsh, Meggan E. Valrance, Andrea Brunet, 2007, Journal of cellular biochemistry.

Vitamin D and Inflammation in Cancer: Emerging Concepts

J. Welsh, M. Tenniswood, Wei-lin Wang, 2013 .

Vitamin D and breast cancer: insights from animal models.

J. Welsh, 2004, The American journal of clinical nutrition.

Modulation and phosphorylation of calbindin-D28K correlates with protein kinase C activation

J. Welsh, A. Gagnon, 1997 .

Differential effects of 1,25-dihydroxyvitamin D3 and tetradecanoylphorbol acetate on cell cycle and apoptosis of MCF-7 cells and a vitamin D3-resistant variant.

J. Welsh, C. Narvaez, 1997, Endocrinology.

Highlights from the 21st Workshop on Vitamin D in Barcelona, May 2018

John H. White, J. Welsh, M. Campbell, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

Over-expression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor null mice

J. Welsh, P. Elias, D. Bikle, 2011, The Journal of investigative dermatology.

Targets of Vitamin D Receptor Signaling in the Mammary Gland

J. Welsh, 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Introduction: Special Issue on Vitamin D Dedicated to the Memory of Anthony W Norman

M. Haussler, J. Welsh, R. Bouillon, 2020, JBMR Plus.

1,25-Dihydroxyvitamin D induces the glutamate transporter SLC1A1 and alters glutamate handling in non-transformed mammary cells

J. Welsh, Sarah G. Beaudin, 2016, Molecular and Cellular Endocrinology.

Estimation of safety/risk profile of the phytoestrogens 8-prenylnaringenin, 6-(1.1-dimethylallyl)naringenin and naringenin in MCF-7 cells and the rat mammary gland

J. Welsh, G. Vollmer, K. Kräker, 2015 .