P. Tullio

发表

Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition

F. Dequiedt, E. Hendrick, P. Peixoto, 2017, Oncogene.

Recent advances in inducible cyclooxygenase (COX-2) inhibition

P. Tullio, J. Dogné, Y. Henrotin, 2000 .

7-chloro-2-methyl-3-methylamino-2H-1,2,4-benzo-thiadiazine 1,1-dioxide

P. Tullio, B. Pirotte, B. Tinant, 2001 .

Semisynthesis and in Vitro Photodynamic Activity Evaluations of Halogenated and Glycosylated Derivatives of Pheophorbide a

L. Angenot, P. Tullio, B. Dejaegher, 2015 .

Nuclear magnetic resonance-based metabolomics of OCT-embedded frozen kidney samples in mouse and man following standardized pre-analytics

P. Tullio, F. Jouret, M. Mourad, 2017, Metabolomics.

Absolute configuration of N-[(R)-3-methyl-2-butyl](S)-2-(6-methoxy-2-naphthyl)propionamide

P. Tullio, B. Pirotte, B. Tinant, 2001 .

Assessing the repeatability and statistical advantages of homonuclear 2D-NMR spectra: a clustering approach

Michel Verleysen, Bernadette Govaerts, Baptiste Feraud, 2013 .

Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer

P. Delvenne, A. Blomme, A. Mouithys-Mickalad, 2017, Oncogene.

PepsNMR for the 1 H-NMR metabolomic data pre-processing

P. Eilers, B. Govaerts, P. Tullio, 2017 .

Synthesis and pharmacology of pyrid-3-ylsulfonylcyanoguanidines as diuretics

P. Tullio, B. Masereel, J. Liégeois, 1995 .

New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position.

P. Tullio, B. Pirotte, P. Lebrun, 2009, Bioorganic & medicinal chemistry.

2,4,7‐Trimethyl‐2,3‐dihydro‐4H‐pyrido[4,3‐e]‐1,2,4‐thiadiazinium 1,1‐Dioxide Iodide

P. Tullio, O. Diouf, B. Masereel, 1995 .

Coupling of LC-MS/MS and LC-SPE-NMR techniques for the structural identification of metabolites following in vitro biotransformation of SUR1-selective KATP channel openers

P. Tullio, P. Chiap, M. Frédérich, 2009 .

Synthesis and pharmacology of pyrid-3-yl sulfonylureas and thioureas as astrocytic Na+ 2Cl- K+ cotransporter inhibitors

P. Tullio, P. Renard, B. Masereel, 1994 .

Statistical treatment of 2D NMR COSY spectra in metabolomics: data preparation, clustering-based evaluation of the Metabolomic Informative Content and comparison with 1H-NMR

M. Verleysen, B. Govaerts, P. Tullio, 2015, Metabolomics.

New substituted aryl esters and aryl amides of 3,4-dihydro-2H-1,2,4- benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors

L. Danober, P. Tullio, P. Lestage, 2011 .

Design, synthesis, and pharmacology of novel 7-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors.

L. Danober, P. Tullio, P. Lestage, 2007, Journal of medicinal chemistry.

New trends in the development of positive allosteric modulators of AMPA receptors

P. Tullio, B. Pirotte, P. Francotte, 2004 .

Synthesis and structural studies of a new class of heterocyclic compounds: 1,2,4-Pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides

P. Tullio, O. Diouf, B. Masereel, 1995 .

Synthesis and structural studies of 3-alkylamino-pyrido[4,3-e]-1,2,4- thiadiazine 1,1-dioxides: A new class of heterocyclic compounds with therapeutical promises

P. Tullio, J. Dogné, B. Pirotte, 1999 .

Study of the ring closure reaction of o-aminoarylsulfonamides with 1,1′-thiocarbonyldiimidazole.

P. Tullio, B. Pirotte, F. Lacan, 1998 .

Synthesis and Biological Evaluation of New 3‐Aralkylamino‐2‐aryl‐2H‐1,2,4‐pyridothiadiazine 1,1‐dioxides as Potential CCK‐Receptor Ligands

P. Tullio, O. Diouf, P. Renard, 1997, The Journal of pharmacy and pharmacology.

Synthesis and Structural Studies of a New Class of Heterocyclic Compounds: 1,2,4-Pyridothiadiazine 1,1-Dioxides, Pyridyl Analogues of 1,2,4-Benzothiadiazine 1,1-Dioxides.

P. Tullio, O. Diouf, B. Masereel, 2010 .

2-Alkyl-3-Alkylamino-2H-Benzo- and Pyridothiadiazine 1,1-Dioxides: From K+ATP Channel Openers to Ca++ Channel Blockers?

P. Tullio, B. Pirotte, M. Antoine, 2002, Biological chemistry.

7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency.

P. Tullio, C. Ptak, R. Oswald, 2018, Journal of medicinal chemistry.

Statistical treatment of 2D-NMR COSY spectra: data preparation, clustering-based repeatability evaluation and comparison with 1H-NMR

Michel Verleysen, Bernadette Govaerts, Baptiste Feraud, 2014 .

Effect of head-to-head addition in vinyl acetate controlled radical polymerization: why is Co(acac)2-mediated polymerization so much better?

P. Tullio, C. Jérôme, C. Detrembleur, 2013 .

Synthesis and vasodilator activity of 3,4-dihydropyrimidin-2(1H)-ones bearing urea, thiourea, and sulfonylurea moieties

P. Tullio, B. Pirotte, G. Faury, 2019, Canadian Journal of Chemistry.

Esters and Amides of 6‐(Chloromethyl)‐2‐oxo‐2H‐1‐benzopyran‐3‐ carboxylic Acid as Inhibitors of α‐Chymotrypsin: Significance of the “Aromatic” Nature of the Novel Ester‐Type Coumarin for Strong Inhibitory Activity.

P. Tullio, B. Masereel, B. Pirotte, 1996 .

Synthesis and biological evaluation of sulfonylcyanoguanidines and sulfonamidonitroethylenes as bioisosteres of hypoglycemic sulfonylureas

P. Tullio, B. Masereel, J. Dogné, 1997 .

Effective resolution of racemic pirlindole at the preparative scale

P. Tullio, P. Hubert, J. Liégeois, 1998 .

Metabolomics Analysis of Galium odoratum (L.) Scop.: Impact of the Plant Population Origin and Growth Conditions

P. Tullio, Y. Choi, M. Tits, 2015 .

3-Alkylamino-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides as Potent KATP-Channel Activators: Structural Study and Influence of Stereochemistry

P. Tullio, B. Pirotte, L. Dupont, 1999 .

Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice

J. Rakic, V. Lambert, J. Foidart, 2013, Nature Protocols.

Independent Component Analysis and Statistical Modelling for the Identification of Metabolomics Biomarkers in 1H-NMR Spectroscopy

M. Verleysen, B. Govaerts, P. Tullio, 2017 .

Codon-specific translation reprogramming promotes resistance to targeted therapy

Sebastian A. Leidel, S. Leidel, B. Charloteaux, 2018, Nature.

Radiotherapy-activated cancer-associated fibroblasts promote tumor progression through paracrine IGF-1 R activation Running title : Irradiated CAF promote tumor progression

A. Vral, C. Vanhove, A. Debucquoy, 2017 .

Effect on insulin release of compounds structurally related to the potassium‐channel opener 7‐chloro‐3‐isopropylamino‐4H‐1,2,4‐benzothiadiazine 1,1‐dioxide (BPDZ 73): introduction of heteroatoms on the 3‐alkylamino side chain of the benzothiadiazine 1,1‐dioxide ring

P. Tullio, B. Pirotte, M. Antoine, 2001, The Journal of pharmacy and pharmacology.

Analytical Tools and Strategic Approach to Detect Poor Quality Medicines, Identify Unknown Components, and Timely Alerts for Appropriate Measures: Case Study of Antimalarial Medicines

Roland Marini Djang’eing’a, P. Tullio, P. Hubert, 2015 .

3‐Isopropylamino‐4‐methyl‐4H‐pyrido[4,3‐e][1,2,4]thiadiazine 1,1‐Dioxide

P. Tullio, B. Pirotte, L. Dupont, 1996 .

Structural Study of Pinacidil, a Potassium‐Channel Opener Belonging to the chemical class of N‐alkyl‐N″‐cyano‐N′‐pyridylguanidines

P. Tullio, B. Masereel, B. Pirotte, 1993 .

A NMR-based metabolomics approach for reducing food losses: the example of minced pork meat

Nicolas Korsak Koulagenko, P. Tullio, G. Daube, 2018 .

First preparative enantiomer resolution of pirlindole, a potent antidepressant drug

P. Tullio, P. Hubert, J. Liégeois, 1998 .

2D-Cosy NMR Spectroscopy as a Quantitative Tool in Biological Matrix: Application to Cyclodextrins

P. Tullio, B. Evrard, Gilles Dufour, 2015, The AAPS Journal.

Frontiers in Medicinal Chemistry

S. A. Hutchinson, H. Wolfson, R. Nussinov, 2016 .

Selective pancreatic ATP-sensitive potassium channel openers for the treatment of glucose homeostasis disorders

P. Tullio, B. Pirotte, M. Antoine, 2006 .

Laser-induced choroidal neovascularization model to study age-related macular degeneration in mice

J. Rakic, V. Lambert, J. Foidart, 2013, Nature Protocols.

V. Lambert, A. Noël, B. Elmoualij, 2013 .

Synthesis and structural studies of a new class of heterocyclic compounds: 1,2,4-Pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides

P. Tullio, O. Diouf, B. Masereel, 1995 .

Biomedical application of NMR metabolomics: study of Age-related Macular Degeneration (AMD)

P. Tullio, 2012 .

ACTIVATION OF THE CALCIUM-SENSING RECEPTOR BEFORE RENAL ISCHEMIA/REPERFUSION EXACERBATES KIDNEY INJURY IN MOUSE

R. Marée, P. Tullio, J. Defraigne, 2014 .

Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition

P. Peixoto, A. Blomme, C. Polese, 2017, Oncogene.

Combining rapid 2D NMR experiments with novel pre-processing workflows and MIC quality measures for metabolomics

Bernadette Govaerts, Patrick Giraudeau, Baptiste Féraud, 2020, Metabolomics.

Cationic and secretory effects of BPDZ 44 and diazoxide in rat pancreatic islets

P. Tullio, A. Herchuelz, B. Pirotte, 1994, Experientia.

2D-Cosy NMR Spectroscopy as a Quantitative Tool in Biological Matrix: Application to Cyclodextrins

P. Tullio, B. Evrard, P. de Tullio, 2015, The AAPS Journal.

Synthesis and structural studies of 3-alkylamino-pyrido[4,3-e]-1,2,4- thiadiazine 1,1-dioxides: A new class of heterocyclic compounds with therapeutical promises

P. Tullio, J. Dogné, B. Pirotte, 1999 .