V. Vasiliou

Ying Chen, V. Vasiliou, D. Nebert, 2013, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Anti-inflammatory agents and inducibility of hepatic drug metabolism

V. Vasiliou, M. Marselos, P. Pappas, 1998, European Journal of Drug Metabolism and Pharmacokinetics.

Phenobarbital inducibility and differences in protein expression of an animal model.

V. Vasiliou, M. Marselos, P. Pappas, 2001, Chemico-biological interactions.

The lack of AHD4 induction by TCDD in corneal cells may involve tissue-specific regulatory proteins.

V. Vasiliou, T. Shiao, 1999, Advances in experimental medicine and biology.

Expression of ALDH3 and NMO1 in human corneal epithelial and breast adenocarcinoma cells.

V. Vasiliou, K. Araki-Sasaki, T. Shiao, 1997, Advances in experimental medicine and biology.

Ontogenesis and expression of ALDH activity in the skin and the eye of the rat.

V. Vasiliou, M. Marselos, P. Pappas, 1997, Advances in experimental medicine and biology.

Studies on the induction of rat class 3 aldehyde dehydrogenase.

V. Vasiliou, M. Marselos, P. Pappas, 1995, Advances in experimental medicine and biology.

Binge ethanol exposure in mice represses expression of genes involved in osteoblast function and induces expression of genes involved in osteoclast differentiation independently of endogenous catalase.

V. Vasiliou, M. Osborn, M. Ronis, 2021, Toxicological sciences : an official journal of the Society of Toxicology.

Transgenic mouse models for alcohol metabolism, toxicity, and cancer.

Ying Chen, D. Thompson, V. Vasiliou, 2015, Advances in experimental medicine and biology.

Ultraviolet radiation: cellular antioxidant response and the role of ocular aldehyde dehydrogenase enzymes.

Ying Chen, D. Thompson, V. Vasiliou, 2011, Eye & contact lens.

Mitochondrial targeting of mouse NQO1 and CYP1B1 proteins.

V. Vasiliou, D. Nebert, F. Gonzalez, 2013, Biochemical and biophysical research communications.

Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency.

A. Matsumoto, V. Vasiliou, K. Wakamatsu, 2019, Chemico-biological interactions.

MOLECULAR CLONING, BACULOVIRUS EXPRESSION, AND TISSUE DISTRIBUTION OF THE ZEBRAFISH ALDEHYDE DEHYDROGENASE 2

Robert L. Tanguay, V. Vasiliou, Aglaia Pappa, 2005, Drug Metabolism and Disposition.

Hepatic metabolic adaptation in a murine model of glutathione deficiency.

Ying Chen, D. Thompson, V. Vasiliou, 2019, Chemico-biological interactions.

Metabolic Remodeling Induced by Mitochondrial Aldehyde Stress Stimulates Tolerance to Oxidative Stress in the Heart

Alexander M. Wolf, V. Vasiliou, M. Suematsu, 2009, Circulation research.

Synergistic inhibition of hepatocellular carcinoma growth by cotargeting chromatin modifying enzymes and poly (ADP‐ribose) polymerases

V. Vasiliou, Da-Qiang Li, L. Mishra, 2012, Hepatology.

Network machine learning maps phytochemically rich “Hyperfoods” to fight COVID-19

M. Bronstein, Guadalupe Gonzalez, I. Laponogov, 2020, Human genomics.

BACULOVIRUS EXPRESSION AND TISSUE DISTRIBUTION OF THE ZEBRAFISH ALDH 2

Robert L. Tanguay, V. Vasiliou, Aglaia Pappa, 2005 .

Ethanol sensitizes skeletal muscle to ammonia-induced molecular perturbations

V. Vasiliou, A. Marini, D. Luse, 2019, The Journal of Biological Chemistry.

Tissue distribution of inducible aldehyde dehydrogenase activity in the rat after treatment with phenobarbital or methylcholanthrene.

V. Vasiliou, M. Marselos, 1989, Pharmacology & toxicology.

Toward Comprehensive Per- and Polyfluoroalkyl Substances Annotation Using FluoroMatch Software and Intelligent High-Resolution Tandem Mass Spectrometry Acquisition.

John A. Bowden, V. Vasiliou, T. Townsend, 2020, Analytical chemistry.

The effects of alcohol and aldehyde dehydrogenases on disorders of hematopoiesis.

V. Vasiliou, M. Gasparetto, Clay Smith, 2015, Advances in experimental medicine and biology.

Focus on molecules: ALDH1A1: from lens and corneal crystallin to stem cell marker.

Vindhya Koppaka, Ying Chen, D. Thompson, 2012, Experimental eye research.

Evolutionary divergence and functions of the ADAM and ADAMTS gene families

Vasilis Vasiliou, C. Brocker, V. Vasiliou, 2009, Human Genomics.

Evaluation of confounding in epidemiologic studies assessing alcohol consumption on the risk of ischemic heart disease

J. Ioannidis, V. Vasiliou, J. Wallach, 2019, BMC Medical Research Methodology.

4-HNE inhibits tube formation and up-regulates chondromodulin-I in human endothelial cells.

V. Vasiliou, D. Ross, D. Stagos, 2009, Biochemical and biophysical research communications.

Ocular Metabolism and Disposition of 4-Hydroxy-2-nonenal

V. Vasiliou, W. Black, 2005 .

Characterization of 4-hydroxy-2-nonenal metabolism in stellate cell lines derived from normal and cirrhotic rat liver.

V. Vasiliou, D. Petersen, J. Reichard, 2000, Biochimica et biophysica acta.

Charkoftaki, Georgia and Rattray, Nicholas J. W. and Andrén, Per E. and Caprioli, Richard M. and Castellino, Steven and Duncan, Mark W. and Goodwin, Richard J. A. and Schey, Kevin L. and Shahidi-Latham, Sheerin

Caroline H. Johnson, R. Caprioli, K. Veselkov, 2019 .

Aldehyde dehydrogenases: from eye crystallins to metabolic disease and cancer stem cells.

Ying Chen, D. Thompson, V. Vasiliou, 2013, Chemico-biological interactions.

Aldehyde dehydrogenase 2 deficiency ameliorates alcoholic fatty liver but worsens liver inflammation and fibrosis in mice

Surendra Singh, A. Matsumoto, V. Vasiliou, 2014, Hepatology.

Update of the NAD(P)H:quinone oxidoreductase (NQO) gene family

V. Vasiliou, D. Nebert, D. Ross, 2006, Human Genomics.

Aldehyde dehydrogenases in acute myeloid leukemia

V. Vasiliou, M. Gasparetto, Clay Smith, 2014, Annals of the New York Academy of Sciences.

Varying levels of aldehyde dehydrogenase activity in adult murine marrow hematopoietic stem cells are associated with engraftment and cell cycle status.

D. Kent, V. Vasiliou, M. Gasparetto, 2012, Experimental hematology.

Aldehyde dehydrogenase gene superfamily: the 2002 update.

V. Vasiliou, N. Sophos, 2003, Chemico-biological interactions.

Eukaryotic aldehyde dehydrogenase (ALDH) genes: human polymorphisms, and recommended nomenclature based on divergent evolution and chromosomal mapping.

A. Bairoch, V. Vasiliou, K. Tipton, 1999, Pharmacogenetics.

Proteomic profiling reveals an association between ALDH and oxidative phosphorylation and DNA damage repair pathways in human colon adenocarcinoma stem cells.

Ying Chen, V. Vasiliou, T. Lam, 2022, Chemico-biological interactions.

Expression, purification and crystallization of the novel Xenopus tropicalis ALDH16B1, a homologue of human ALDH16A1.

Ying Chen, D. Thompson, V. Vasiliou, 2019, Chemico-biological interactions.

Removal of acetaldehyde from the body.

V. Vasiliou, D. Petersen, R. Deitrich, 2007, Novartis Foundation symposium.

Corneal haze phenotype in Aldh3a1-null mice: In vivo confocal microscopy and tissue imaging mass spectrometry.

Ying Chen, D. Thompson, V. Vasiliou, 2017, Chemico-biological interactions.

The Aldehyde Dehydrogenase Gene Superfamily Resource Center

V. Vasiliou, W. Black, 2009, Human Genomics.

Placing human gene families into their evolutionary context

Zheng Wang, J. Townsend, E. Bruford, 2022, Human Genomics.

Summary of the 2019 Alcohol and Immunology Research Interest Group (AIRIG) meeting: Alcohol-mediated mechanisms of multiple organ injury.

V. Vasiliou, F. Bishehsari, P. Mandrekar, 2020, Alcohol.

4.07 – Aldehyde Dehydrogenases

V. Vasiliou, D. Petersen, 2010 .

Changes in the inducibility of a hepatic aldehyde dehydrogenase by various effectors

V. Vasiliou, M. Marselos, 2004, Archives of Toxicology.

Changes in the Inducibility of a Hepatic Aldehyde Dehydrogenase

V. Vasiliou, M. Marselos, M. Karageorgou, 1991 .

Effects of Cannabis and Tobacco on the Ezymes of Alcohol Metabolism in the Rat

V. Vasiliou, M. Marselos, M. Malamasi,, 1991, Reviews on environmental health.

Effect of various chemicals on the aldehyde dehydrogenase activity of the rat liver cytosol.

V. Vasiliou, M. Marselos, 1991, Chemico-biological interactions.

Inducibility of liver cytosolic aldehyde dehydrogenase activity in various animal species.

M. Malamas, V. Vasiliou, M. Marselos, 1989, Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology.

The mechanism of alcohol intolerance produced by various therapeutic agents.

M. Malamas, V. Vasiliou, M. Marselos, 2009, Acta pharmacologica et toxicologica.

Artificial turf and crumb rubber infill: An international policy review concerning the current state of regulations

V. Vasiliou, N. Ratola, A. Watterson, 2022, Environmental challenges.

Zoxazolamine-induced paralysis in two rat substrains: differences in hepatic drug metabolism

V. Vasiliou, M. Marselos, P. Pappas, 1998, European Journal of Drug Metabolism and Pharmacokinetics.

Comparative genomics, molecular evolution and computational modeling of ALDH1B1 and ALDH2.

Brian C. Jackson, B. Jackson, D. Thompson, 2013, Chemico-biological interactions.

Nutrient Composition and Fatty Acid and Protein Profiles of Selected Fish By-Products

V. Vasiliou, Aikaterini Kandyliari, M. Kapsokefalou, 2020, Foods.

Aldehyde dehydrogenase (ALDH) superfamily in plants: gene nomenclature and comparative genomics

Xiping Wang, C. Brocker, V. Vasiliou, 2012, Planta.

Molecular Cloning and Oxidative Modification of Human Lens ALDH1A1: Implication in Impaired Detoxification of Lipid Aldehydes

Min Zhang, Vasilis Vasiliou, Min Zhang, 2009, Journal of toxicology and environmental health. Part A.

Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity

Adam Yasgar, A. Jadhav, V. Vasiliou, 2018, Journal of medicinal chemistry.

Environmental lipidomics: understanding the response of organisms and ecosystems to a changing world

John A. Bowden, M. Prasad, V. Vasiliou, 2020, Metabolomics.

Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation

Tingting Wang, Vasilis Vasiliou, Ruohan Wu, 2018, eLife.

Role of CYP1B1 in glaucoma.

V. Vasiliou, F. Gonzalez, 2008, Annual review of pharmacology and toxicology.

Racemic Salsolinol and its Enantiomers Act as Agonists of the μ-Opioid Receptor by Activating the Gi Protein-Adenylate Cyclase Pathway

V. Vasiliou, M. Herrera-Marschitz, M. E. Quintanilla, 2017, Front. Behav. Neurosci..

Identification of dose-dependent DNA damage and repair responses from subchronic exposure to 1,4-dioxane in mice using a systems analysis approach.

Caroline H. Johnson, Ying Chen, V. Vasiliou, 2021, Toxicological sciences : an official journal of the Society of Toxicology.

Novel insights into the mode of action of 1,4-dioxane using a systems screening approach

Caroline H. Johnson, Ying Chen, D. Thompson, 2020, bioRxiv.

SARS-CoV-2 wastewater surveillance data can predict hospitalizations and ICU admissions

Nikiforos A Alygizakis, M. Dimopoulos, A. Scorilas, 2021, Science of The Total Environment.

The genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy due to mutations in ALDH7A1

C. Brocker, V. Vasiliou, J. V. Van Hove, 2010, Journal of Inherited Metabolic Disease.

Antioxidant defenses in the ocular surface.

Ying Chen, V. Vasiliou, G. Mehta, 2009, The ocular surface.

Human aldehyde dehydrogenase 3A1 (ALDH3A1): biochemical characterization and immunohistochemical localization in the cornea.

V. Vasiliou, Aglaia Pappa, Donald J. Brown, 2003, The Biochemical journal.

10.07 – Aldehyde Dehydrogenases☆

V. Vasiliou, 2018 .

Corneal aldehyde dehydrogenases: Multiple functions and novel nuclear localization

Ying Chen, V. Vasiliou, J. Jester, 2010, Brain Research Bulletin.

Analysis and update of the human aldehyde dehydrogenase (ALDH) gene family

Vasilis Vasiliou, V. Vasiliou, D. Nebert, 2005, Human Genomics.

Development and Initial Characterization of the Aldh1a1(–/–)/Aldh3a1(–/–) Double Knockout Mice

V. Vasiliou, J. Piatigorsky, G. Duester, 2005 .

Aldh3a1 protects human corneal epithelial cells from ultraviolet- and 4-hydroxy-2-nonenal-induced oxidative damage.

Y. Koutalos, V. Vasiliou, A. Townsend, 2003, Free radical biology & medicine.

Corneal and stomach expression of aldehyde dehydrogenases: from fish to mammals.

V. Vasiliou, Aglaia Pappa, N. Sophos, 2001, Chemico-biological interactions.

Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2

Brian C. Jackson, A. Jimeno, L. Wakefield, 2017, Journal of the National Cancer Institute.

Structural and Functional Modifications of Corneal Crystallin ALDH3A1 by UVB Light

Ying Chen, V. Vasiliou, J. Carpenter, 2010, PloS one.

Aldehyde dehydrogenase 7A1 (ALDH7A1) attenuates reactive aldehyde and oxidative stress induced cytotoxicity.

C. Brocker, V. Vasiliou, P. Failli, 2011, Chemico-biological interactions.

Aldehyde Dehydrogenase Inhibitors: a Comprehensive Review of the Pharmacology, Mechanism of Action, Substrate Specificity, and Clinical Application

Vindhya Koppaka, Ying Chen, D. Thompson, 2012, Pharmacological Reviews.

Analysis of the glutathione S-transferase (GST) gene family

V. Vasiliou, D. Nebert, 2004, Human Genomics.

Mouse Models of the Cornea and Lens: Understanding Ocular Disease

V. Vasiliou, S. Marchitti, J. Petrash, 2008 .

Overview of PAX gene family: analysis of human tissue-specific variant expression and involvement in human disease

Hongyu Zhao, E. Dermitzakis, E. Bruford, 2020, Human Genetics.

Aldehyde Dehydrogenase 7A1 (ALDH7A1) Is a Novel Enzyme Involved in Cellular Defense against Hyperosmotic Stress*

K. Kavanagh, C. Brocker, V. Vasiliou, 2010, The Journal of Biological Chemistry.

The role of hyperosmotic stress in inflammation and disease

C. Brocker, D. Thompson, V. Vasiliou, 2012, Biomolecular concepts.

Update of the keratin gene family: evolution, tissue-specific expression patterns, and relevance to clinical disorders

E. Bruford, V. Vasiliou, D. Nebert, 2022, Human genomics.

Enzymatic mechanisms of ethanol oxidation in the brain.

V. Vasiliou, F. Gonzalez, R. Deitrich, 2006, Alcoholism, clinical and experimental research.

Arachidonic acid suppresses growth of human lung tumor A549 cells through down-regulation of ALDH3A1 expression.

Vasilis Vasiliou, V. Vasiliou, G. Muzio, 2006, Free radical biology & medicine.

A new era in the discovery of de novomutations underlying human genetic disease

D. Cooper, V. Vasiliou, C. Ku, 2012, Human Genomics.

Glutathione and Transsulfuration in Alcohol-Associated Tissue Injury and Carcinogenesis.

Ying Chen, A. Matsumoto, D. Thompson, 2018, Advances in experimental medicine and biology.

Update of human and mouse forkhead box (FOX) gene families

Brian C. Jackson, V. Vasiliou, D. Nebert, 2010, Human Genomics.

Genome-Wide Identification and Analysis of Grape Aldehyde Dehydrogenase (ALDH) Gene Superfamily

Z. Fei, Xiping Wang, C. Brocker, 2012, PloS one.

Glutathione Primes T Cell Metabolism for Inflammation

T. Mak, C. Bindslev‐Jensen, Ying Chen, 2017, Immunity.

Biological Basis of Alcohol-Induced Cancer

J. Hoek, V. Vasiliou, H. Seitz, 2015, Advances in Experimental Medicine and Biology.

Integrated multi-omics approach reveals a role of ALDH1A1 in lipid metabolism in human colon cancer cells.

D. Thompson, V. Vasiliou, T. Lam, 2019, Chemico-biological interactions.

Hepatic and Extrahepatic Malignancies in Alcoholic Liver Disease

V. Vasiliou, S. Radaeva, S. Zakhari, 2016 .

Beyond genomics: understanding exposotypes through metabolomics

Caroline H. Johnson, J. Ioannidis, V. Vasiliou, 2018, Human Genomics.

Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues.

Ying Chen, V. Vasiliou, Brian Thompson, 2022, Chemico-biological interactions.

Oxidative stress induces inflammation of lens cells and triggers immune surveillance of ocular tissues

Ying Chen, V. Vasiliou, Brian Thompson, 2021, bioRxiv.

Update of human and mouse matrix metalloproteinase families

Brian C. Jackson, V. Vasiliou, D. Nebert, 2010, Human Genomics.

Engineered Animal Models Designed for Investigating Ethanol Metabolism, Toxicity and Cancer.

Surendra Singh, Ying Chen, D. Thompson, 2018, Advances in experimental medicine and biology.

Quantification of Neural Ethanol and Acetaldehyde Using Headspace GC-MS.

D. Thompson, V. Vasiliou, G. Charkoftaki, 2016, Alcoholism, clinical and experimental research.

The role of CYP2E1 in alcohol metabolism and sensitivity in the central nervous system.

Ying Chen, D. Thompson, V. Vasiliou, 2013, Sub-cellular biochemistry.

CYP2E1 and catalase influence ethanol sensitivity in the central nervous system

V. Vasiliou, D. Petersen, F. Gonzalez, 2006, Pharmacogenetics and genomics.

Mouse Dioxin-Inducible Ahd4 Gene

V. Vasiliou, D. Nebert, A. Puga, 1996 .

COVID-19 vulnerability: the potential impact of genetic susceptibility and airborne transmission

C. D. Dela Cruz, D. Thompson, V. Vasiliou, 2020, Human Genomics.

Role of Human Aldehyde Dehydrogenases in Endobiotic and Xenobiotic Metabolism

V. Vasiliou, Aglaia Pappa, Tia Estey, 2004, Drug metabolism reviews.

Early onset senescence occurs when fibroblasts lack the glutamate-cysteine ligase modifier subunit.

V. Vasiliou, D. Nebert, T. Dalton, 2009, Free radical biology & medicine.

Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function.

P. Wilmes, T. Mak, Ying Chen, 2020, Cell metabolism.

Gclc deletion in surface-ectoderm tissues induces microphthalmia

Ying Chen, D. Thompson, V. Vasiliou, 2019, bioRxiv.

Molecular Pathway Analysis Indicates a Distinct Metabolic Phenotype in Women With Right-Sided Colon Cancer

Caroline H. Johnson, Ying Chen, V. Vasiliou, 2019, Translational oncology.

Molecular pathway analysis indicates a distinct metabolic and immune phenotype in women with right-sided colon cancer

Caroline H. Johnson, Ying Chen, V. Vasiliou, 2019, bioRxiv.

Genetics and functions of the retinoic acid pathway, with special emphasis on the eye

D. Thompson, V. Vasiliou, N. Katsanis, 2019, Human Genomics.

Beyond genomics: understanding exposotypes through metabolomics

Caroline H. Johnson, J. Ioannidis, V. Vasiliou, 2018, Human Genomics.

Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an “evolutionary bloom”

E. Bruford, D. Thompson, V. Vasiliou, 2019, Human Genomics.

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

Adam Yasgar, A. Jadhav, V. Vasiliou, 2017, PloS one.

Role of mitochondrial aldehyde dehydrogenase in nitrate tolerance.

V. Vasiliou, G. Thatcher, B. Bennett, 2003, Molecular pharmacology.

Interplay between APC and ALDH1B1 in a newly developed mouse model of colorectal cancer.

Ying Chen, D. Thompson, V. Vasiliou, 2020, Chemico-biological interactions.

Importance of inverse correlation between ALDH3A1 and PPARγ in tumor cells and tissue regeneration.

V. Vasiliou, A. Chiaravalloti, M. Maggiora, 2011, Chemico-biological interactions.

Update of the human and mouse SERPIN gene superfamily

Mathew W. Wright, Vasilis Vasiliou, Brian C. Jackson, 2013, Human Genomics.

Update on the aldehyde dehydrogenase gene (ALDH) superfamily

Brian C. Jackson, C. Brocker, D. Thompson, 2011, Human Genomics.

Alcohol consumption and risk of stomach cancer: a meta-analysis.

V. Vasiliou, Yawei Zhang, Lan Jin, 2021, Chemico-biological interactions.

COVID-19 one year into the pandemic: from genetics and genomics to therapy, vaccination, and policy

V. Vasiliou, J. Reichardt, L. Luzzatto, 2021, Human genomics.

Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma

Surendra Singh, Ying Chen, D. Thompson, 2016, Pancreas.

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family Published, JLR Papers in Press, August 1, 2004. DOI 10.1194/jlr.E400002-JLR200

Lois J. Maltais, Alessandra Renieri, David A. Bernlohr, 2004, Journal of Lipid Research.

Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells

Ying Chen, V. Vasiliou, M. Kleinewietfeld, 2022, Nature Communications.

Characterization of aldehyde dehydrogenase isozymes in ovarian cancer tissues and sphere cultures

R. Berkowitz, Surendra Singh, D. Thompson, 2012, BMC Cancer.

Discovery of NCT-501, a Potent and Selective Theophylline-Based Inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1).

M. Ferrer, Adam Yasgar, A. Jadhav, 2015, Journal of medicinal chemistry.

The exposome in practice: an exploratory panel study of biomarkers of air pollutant exposure in Chinese people aged 60-69 years (China BAPE Study).

H. Kan, V. Vasiliou, Tianwei Yu, 2021, Environment international.

Aldehyde dehydrogenase 1B1 (ALDH1B1) is a potential biomarker for human colon cancer.

Surendra Singh, Ying Chen, A. Matsumoto, 2011, Biochemical and biophysical research communications.

Multiple and Additive Functions of ALDH3A1 and ALDH1A1

Vasilis Vasiliou, J. Kuszak, J. Bateman, 2007, Journal of Biological Chemistry.

Scallop lens Ω-crystallin (ALDH1A9): A novel tetrameric aldehyde dehydrogenase

Vasilis Vasiliou, V. Vasiliou, J. Piatigorsky, 2006 .

Molecular cloning and baculovirus expression of the rabbit corneal aldehyde dehydrogenase (ALDH1A1) cDNA.

V. Vasiliou, D. Petersen, Aglaia Pappa, 2003, DNA and cell biology.

Antioxidant function of corneal ALDH3A1 in cultured stromal fibroblasts.

V. Vasiliou, J. Jester, Aglaia Pappa, 2006, Free radical biology & medicine.

Environmental Influences in the Etiology of Colorectal Cancer: the Premise of Metabolomics

Caroline H. Johnson, V. Vasiliou, N. Rattray, 2017, Current Pharmacology Reports.

Alcohol and Cancer: Existing Knowledge and Evidence Gaps across the Cancer Continuum

V. Vasiliou, S. Gapstur, K. Shield, 2021, Cancer Epidemiology, Biomarkers & Prevention.

Targeted therapy for a subset of acute myeloid leukemias that lack expression of aldehyde dehydrogenase 1A1

John M. Ashton, Jason R. Myers, V. Vasiliou, 2017, Haematologica.

Aldehyde dehydrogenase 3B1 (ALDH3B1): immunohistochemical tissue distribution and cellular-specific localization in normal and cancerous human tissues.

C. Brocker, V. Vasiliou, D. Orlicky, 2010, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Oral N-acetylcysteine rescues lethality of hepatocyte-specific Gclc-knockout mice, providing a model for hepatic cirrhosis.

V. Vasiliou, D. Nebert, D. Orlicky, 2010, Journal of hepatology.

Molecular mechanisms of ALDH3A1-mediated cellular protection against 4-hydroxy-2-nonenal.

Ying Chen, A. Matsumoto, D. Thompson, 2012, Free radical biology & medicine.

Molecular characterization, expression analysis, and role of ALDH3B1 in the cellular protection against oxidative stress.

C. Brocker, V. Vasiliou, D. Orlicky, 2010, Free radical biology & medicine.

Aldehyde Dehydrogenase 1B1: Molecular Cloning and Characterization of a Novel Mitochondrial Acetaldehyde-Metabolizing Enzyme

Brian C. Jackson, C. Brocker, Ying Chen, 2010, Drug Metabolism and Disposition.

Aldehyde Dehydrogenase 3B1 (ALDH3B1): Immunohistochemical Tissue Distribution and Cellular-specific Localization in Normal and Cancerous Human Tissues

C. Brocker, V. Vasiliou, D. Orlicky, 2010 .

Expression and initial characterization of human ALDH3B1.

V. Vasiliou, D. Orlicky, S. Marchitti, 2007, Biochemical and biophysical research communications.

Mechanisms Involved in the Protection of UV-induced Protein Inactivation by the Corneal Crystallin ALDH3A1*

V. Vasiliou, J. Carpenter, Tia Estey, 2007, Journal of Biological Chemistry.

Polymorphisms of Human Aldehyde Dehydrogenases

V. Vasiliou, Aglaia Pappa, 2000, Pharmacology.

Regulation of [Ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[1,2-b]indole in mouse hepatoma cell lines.

V. Vasiliou, D. Nebert, H. Zhu, 1994, Carcinogenesis.

Glutathione Primes T Cell Metabolism for Inflammation.

Markus Ollert, Karsten Hiller, Carole Binsfeld, 2017, Immunity.

Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer

Surendra Singh, Ying Chen, A. Matsumoto, 2017, British Journal of Cancer.

ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways

A. Jimeno, Surendra Singh, Ying Chen, 2015, PloS one.

Acetaldehyde and retinaldehyde-metabolizing enzymes in colon and pancreatic cancers.

V. Vasiliou, J. Arcaroli, W. Messersmith, 2015, Advances in experimental medicine and biology.

Welcome back to Human Genomics.

V. Vasiliou, 2008, Human genomics.

Catalase deletion promotes prediabetic phenotype in mice

Hongyu Zhao, D. Thompson, V. Vasiliou, 2017, Free radical biology & medicine.

Duane Retraction Syndrome, Nystagmus, Retinal Pigment Epitheliopathy and Epiretinal Membrane with Micro- and Pachygyria, Developmental Delay, Hearing Loss and Craniopharyngioma

J. Bateman, V. Vasiliou, N. Lassen, 2009, Ophthalmic genetics.

Extrahepatic expression of NAD(P)H:menadione oxidoreductase, UDP glucuronosyltransferase-1A6, microsomal aldehyde dehydrogenase, and hepatic nuclear factor-1 alpha mRNAs in ch/ch and 14CoS/14CoS mice.

V. Vasiliou, D. Nebert, S. Reuter, 1997, Biochemical and biophysical research communications.

Molecular Mechanisms of Alcohol-Induced Colorectal Carcinogenesis

Caroline H. Johnson, Surendra Singh, V. Vasiliou, 2021, Cancers.

Update of the human secretoglobin (SCGB) gene superfamily and an example of 'evolutionary bloom' of androgen-binding protein genes within the mouse Scgb gene superfamily

Mathew W. Wright, Brian C. Jackson, D. Thompson, 2011, Human Genomics.

Gene array profiles of alcohol and aldehyde metabolizing enzymes in brains of C57BL/6 and DBA/2 mice.

V. Vasiliou, B. Tabakoff, P. Hoffman, 2006, Alcoholism, clinical and experimental research.

Cyclophilin nomenclature problems, or, 'a visit from the sequence police'

V. Vasiliou, D. Nelson, D. Nebert, 2004, Human Genomics.

Evolutionary divergence and functions of the human acyl-CoA thioesterase gene (ACOT) family

C. Brocker, V. Vasiliou, D. Nebert, 2010, Human Genomics.

Exposure to per- and Polyfluoroalkyl Substances and Markers of Liver Injury: A Systematic Review and Meta-Analysis

L. Chatzi, D. Conti, V. Vasiliou, 2022, Environmental health perspectives.

Non-targeted metabolomics and associations with per- and polyfluoroalkyl substances (PFAS) exposure in humans: A scoping review.

Caroline H. Johnson, V. Vasiliou, K. Nyhan, 2022, Environment international.

COVID-19 update: the first 6 months of the pandemic

V. Vasiliou, J. Reichardt, R. Mehrian-Shai, 2020, Human genomics.

Zinc levels and birth weight in pregnant women with gestational diabetes mellitus: a matched cohort study in China.

V. Vasiliou, N. Deziel, Hailan Yang, 2020, The Journal of clinical endocrinology and metabolism.

Prediction of Drug Response and Safety in Clinical Practice

V. Vasiliou, K. Heard, A. Monte, 2011, Journal of Medical Toxicology.

In Silico Exploration of the Potential Role of Acetaminophen and Pesticides in the Etiology of Autism Spectrum Disorder

V. Vasiliou, S. Whirledge, Z. Liew, 2021, Toxics.

AMPK activators for the prevention and treatment of neurodegenerative diseases

V. Vasiliou, David C. Thompson, Natalie Neumann, 2021, Expert opinion on drug metabolism & toxicology.

Lipid Annotator: Towards Accurate Annotation in Non-Targeted Liquid Chromatography High-Resolution Tandem Mass Spectrometry (LC-HRMS/MS) Lipidomics Using a Rapid and User-Friendly Software

John A. Bowden, Mikiko Takahashi, John A Bowden, 2020, Metabolites.

Discovery of a Novel Class of Covalent Inhibitor for Aldehyde Dehydrogenases*

Daria Mochly-Rosen, Jeewon Kim, Vasilis Vasiliou, 2011, The Journal of Biological Chemistry.

Duplicated gelsolin family genes in zebrafish: a novel scinderin‐like gene (scinla) encodes the major corneal crystallin

E. Koonin, Y. Wolf, V. Vasiliou, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Improved drug therapy: triangulating phenomics with genomics and metabolomics

C. Brocker, V. Vasiliou, D. Nebert, 2014, Human Genomics.

Involvement of the electrophile responsive element and p53 in the activation of hepatic stellate cells as a response to electrophile menadione.

V. Vasiliou, D. Petersen, Aglaia Pappa, 2003, Archives of biochemistry and biophysics.

Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity.

A. Matsumoto, D. Thompson, V. Vasiliou, 2014, Free radical biology & medicine.

Nitrogen mustard-induced corneal injury involves the sphingomyelin-ceramide pathway.

D. Thompson, V. Vasiliou, J. Jester, 2018, The ocular surface.

Glutathione supports lipid abundance in vivo

Ying Chen, V. Vasiliou, I. Harris, 2023, bioRxiv.

Retinoic acid biosynthesis catalyzed by retinal dehydrogenases relies on a rate-limiting conformational transition associated with substrate recognition.

V. Vasiliou, G. Branlant, F. Talfournier, 2013, Chemico-biological interactions.

Human ALDH1B1 Polymorphisms may Affect the Metabolism of Acetaldehyde and All-trans retinaldehyde—In Vitro Studies and Computational Modeling

Brian C. Jackson, D. Thompson, V. Vasiliou, 2015, Pharmaceutical Research.

Chronic Glutathione Depletion Confers Protection against Alcohol-induced Steatosis: Implication for Redox Activation of AMP-activated Protein Kinase Pathway

Surendra Singh, Ying Chen, A. Matsumoto, 2016, Scientific Reports.

Algorithmic Learning for Auto-deconvolution of GC-MS Data to Enable Molecular Networking within GNPS

Wout Bittremieux, Alexander A. Aksenov, Yann Guitton, 2020, bioRxiv.

Auto-deconvolution and molecular networking of gas chromatography–mass spectrometry data

Wout Bittremieux, Zheng Zhang, Yann Guitton, 2020, Nature Biotechnology.

Oxidative Stress, Glutathione and CYP2E1 in 1,4-Dioxane Liver Cytotoxicity and Genotoxicity: Insights from Animal Models

Ying Chen, V. Vasiliou, D. Orlicky, 2022, Current Opinion in Environmental Science & Health.

1,4-Dioxane as an emerging water contaminant: State of the science and evaluation of research needs.

Caroline H. Johnson, P. Anastas, D. Thompson, 2019, The Science of the total environment.

Human ALDH1B1 Polymorphisms may Affect the Metabolism of Acetaldehyde and All-trans retinaldehyde—In Vitro Studies and Computational Modeling

Brian C. Jackson, V. Vasiliou, P. Reigan, 2014, Pharmaceutical Research.

Human aldehyde dehydrogenase genes: alternatively spliced transcriptional variants and their suggested nomenclature

A. Bairoch, V. Vasiliou, K. Tipton, 2009, Pharmacogenetics and genomics.

Transcriptomic analysis and plasma metabolomics in Aldh16a1-null mice reveals a potential role of ALDH16A1 in renal function.

Hongyu Zhao, Ying Chen, D. Thompson, 2017, Chemico-biological interactions.

ALDH16A1 is a novel non-catalytic enzyme that may be involved in the etiology of gout via protein-protein interactions with HPRT1.

Brian C. Jackson, Vindhya Koppaka, Ying Chen, 2013, Chemico-biological interactions.

Prepubertal regulation of the rat dioxin-inducible aldehyde dehydrogenase (ALDH3).

V. Vasiliou, M. Marselos, P. Pappas, 1999, Advances in experimental medicine and biology.

Ligands of four receptors in the nuclear steroid/thyroid hormone superfamily inhibit induction of rat cytosolic aldehyde dehydrogenase-3 (ALDH3c) by 3-methylcholanthrene.

V. Vasiliou, D. Nebert, M. Marselos, 1995, Biochemical pharmacology.

Author response: Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation

D. Green, Ying Chen, V. Vasiliou, 2018 .

Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

Adam Yasgar, A. Jadhav, V. Vasiliou, 2018, PloS one.

Antiproliferative activity of protein hydrolysates derived from fish by-products on human colon and breast cancer cells.

Ying Chen, V. Vasiliou, Aikaterini Kandyliari, 2020, Proceedings of the Nutrition Society.

Ultraviolet radiation decreases expression and induces aggregation of corneal ALDH3A1.

V. Vasiliou, J. Carpenter, Aglaia Pappa, 2003, Chemico-biological interactions.

Impaired GSH biosynthesis disrupts eye development, lens morphogenesis and PAX6 function.

Ying Chen, V. Vasiliou, Brian Thompson, 2021, The ocular surface.

Evaluation of potential carcinogenicity of organic chemicals in synthetic turf crumb rubber

Caroline H. Johnson, D. Thompson, V. Vasiliou, 2019, Environmental research.

Aldehyde dehydrogenases are regulators of hematopoietic stem cell numbers and B-cell development.

C. Brocker, Ying Chen, V. Vasiliou, 2012, Experimental hematology.

Genetic tests obtainable through pharmacies: the good, the bad, and the ugly

Darrol J. Baker, George P Patrinos, David N Cooper, 2013, Human Genomics.

Update of the human and mouse Fanconi anemia genes

E. Bruford, D. Thompson, V. Vasiliou, 2015, Human Genomics.

Prioritization of reproductive toxicants in unconventional oil and gas operations using a multi-country regulatory data-driven hazard assessment.

V. Vasiliou, N. Deziel, S. Inayat-Hussain, 2018, Environment international.

Improved drug therapy: triangulating phenomics with genomics and metabolomics

C. Brocker, D. Thompson, V. Vasiliou, 2014, Human Genomics.

Mechanistic Considerations in 1,4-Dioxane Cancer Risk Assessment.

Ying Chen, V. Vasiliou, G. Ginsberg, 2022, Current opinion in environmental science & health.

Genetic differences in alcohol drinking preference between inbred strains of mice.

V. Vasiliou, D. Nebert, H. Zhu, 1997, Pharmacogenetics (London).

Aldehyde dehydrogenase gene superfamily: the 2000 update.

V. Vasiliou, Aglaia Pappa, T. L. Ziegler, 2001, Chemico-biological interactions.

Involvement of p65 in the regulation of NF-kappaB in rat hepatic stellate cells during cirrhosis.

V. Vasiliou, D. Petersen, Aglaia Pappa, 2000, Biochemical and biophysical research communications.

Alzheimer’s disease: using gene/protein network machine learning for molecule discovery in olive oil

Guadalupe Gonzalez, I. Laponogov, K. Veselkov, 2023, Human Genomics.

Aldehyde Dehydrogenase Gene Superfamily

V. Vasiliou, T. L. Ziegler, 1999 .

A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation

B. Becher, Ying Chen, V. Vasiliou, 2023, bioRxiv.

Yale School of Public Health Symposium on tissue imaging mass spectrometry: illuminating phenotypic heterogeneity and drug disposition at the molecular level

Caroline H. Johnson, R. Caprioli, K. Veselkov, 2018, Human Genomics.

Genomics of COVID-19: molecular mechanisms going from susceptibility to severity of the disease

V. Vasiliou, J. Reichardt, R. Mehrian-Shai, 2020, Human Genomics.

Associations between per- and polyfluoroalkyl substances, liver function, and daily alcohol consumption in a sample of U.S. adults.

V. Vasiliou, T. VoPham, J. Fisher, 2023, Environmental research.

A Novel Technique for Redox Lipidomics Using Mass Spectrometry: Application on Vegetable Oils Used to Fry Potatoes.

John A. Bowden, V. Vasiliou, Juan J. Aristizabal-Henao, 2021, Journal of the American Society for Mass Spectrometry.

Use of Untargeted Metabolomics to Explore the Air Pollution-Related Disease Continuum

Caroline H. Johnson, V. Vasiliou, K. G. Godri Pollitt, 2021, Current Environmental Health Reports.

Editorial

V. Vasiliou, 2009, Human Genomics.

Mouse microsomal Class 3 aldehyde dehydrogenase: AHD3 cDNA sequence, inducibility by dioxin and clofibrate, and genetic mapping.

V. Vasiliou, C. Kozak, D. Nebert, 1996, DNA and cell biology.

Mouse class 3 aldehyde dehydrogenases.

V. Vasiliou, C. Kozak, D. Nebert, 1995, Advances in experimental medicine and biology.

Mouse class 3 aldehyde dehydrogenases: positive and negative regulation of gene expression.

V. Vasiliou, D. Nebert, A. Puga, 1993, Advances in experimental medicine and biology.

A new era in the discovery of de novo mutations underlying human genetic disease

D. Cooper, V. Vasiliou, C. Ku, 2012, Human Genomics.

COVID-19 annual update: a narrative review

V. Vasiliou, N. Kaminski, A. Ko, 2023, Human Genomics.

The Use of ALDH Induction as a Carcinogenic Risk Marker in Comparison with Typical in Vitro Mutagenicity System

V. Vasiliou, M. Marselos, K. Athanasiou, 1989 .

Assessing extraction-analysis methodology to detect fluorotelomer alcohols (FTOH), a class of perfluoroalkyl and polyfluoroalkyl substances (PFAS), in artificial turf fibers and crumb rubber infill

V. Vasiliou, Emily A. Davidson, David C. Thompson, 2022, Case Studies in Chemical and Environmental Engineering.

ALDH1B1 links alcohol consumption and diabetes.

Surendra Singh, Ying Chen, A. Matsumoto, 2015, Biochemical and biophysical research communications.

Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions

Y. Kluger, V. Vasiliou, R. Flavell, 2023, Cell.

Ultraviolet radiation: cellular antioxidant response and the role of ocular aldehyde dehydrogenase enzymes.

Ying Chen, D. Thompson, V. Vasiliou, 2011 .

Four amino acid changes are associated with the Aldh3a1 locus polymorphism in mice which may be responsible for corneal sensitivity to ultraviolet light.

V. Vasiliou, T. Shiao, D. Siegel, 1999, Pharmacogenetics.

An AI-powered patient triage platform for future viral outbreaks using COVID-19 as a disease model

Elizabeth B White, M. C. Muenker, S. Farhadian, 2023, Human Genomics.

Environmental lipidomics: understanding the response of organisms and ecosystems to a changing world

John A. Bowden, M. Prasad, V. Vasiliou, 2020, Metabolomics.

Multi-omics profiling reveals cellular pathways and functions regulated by ALDH1B1 in colon cancer cells.

Ying Chen, V. Vasiliou, G. Charkoftaki, 2023, Chemico-biological interactions.

Aldehyde dehydrogenases in acute myeloid leukemia

V. Vasiliou, M. Gasparetto, Clay Smith, 2014, Annals of the New York Academy of Sciences.

Aldehyde dehydrogenase (ALDH) superfamily in plants: gene nomenclature and comparative genomics

Xiping Wang, V. Vasiliou, A. Wood, 2012, Planta.

Prevalence and significance of race and ethnicity subgroup analyses in Cochrane intervention reviews

J. Ioannidis, V. Vasiliou, J. Wallach, 2019, Clinical trials.

Regularized Multivariate Analysis of Variance

V. Vasiliou, G. Charkoftaki, J. Engel, 2020 .

Scientific evidence supporting the newly developed one-health labeling tool “Med-Index”: an umbrella systematic review on health benefits of mediterranean diet principles and adherence in a planeterranean perspective

M. L. Clodoveo, A. Trichopoulou, V. Vasiliou, 2023, Journal of Translational Medicine.

Molecular Cloning and Oxidative Modification of Human Lens ALDH1A1: Implication in Impaired Detoxification of Lipid Aldehydes

Min Zhang, V. Vasiliou, K. Ramana, 2009, Journal of toxicology and environmental health. Part A.