C. Tepper

C. Tepper, D. Gandara, H. Kung, 2009, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Histone Demethylase JMJD2A Regulates Kaposi's Sarcoma-Associated Herpesvirus Replication and Is Targeted by a Viral Transcriptional Factor

K. Lam, C. Tepper, H. Kung, 2011, Journal of Virology.

A distinct subpopulation of leukemia initiating cells in acute precursor B lymphoblastic leukemia: quiescent phenotype and unique transcriptomic profile

J. McPherson, C. Tepper, N. Satake, 2022, Frontiers in Oncology.

Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization.

C. Tepper, H. Kung, R. deVere White, 2012, Endocrine-related cancer.

Resistance of mitochondrial DNA to degradation characterizes the apoptotic but not the necrotic mode of human leukemia cell death

C. Tepper, G. P. Studzinski, 1993, Journal of cellular biochemistry.

1,25-Dihydroxyvitamin D3 protects HL60 cells against apoptosis but down-regulates the expression of the bcl-2 gene.

C. Tepper, J. Jones, G. P. Studzinski, 1993, Experimental cell research.

Inappropriate activation of androgen receptor by relaxin via β-catenin pathway

C. Tepper, H. Kung, R. Gandour-Edwards, 2008, Oncogene.

Recombinant Origin of the Retrovirus XMRV

V. Pathak, Wei-Shau Hu, C. Tepper, 2011, Science.

Multiomic analysis for optimization of combined focal and immunotherapy protocols in murine pancreatic cancer

Aaron M. Newman, A. Newman, S. Aviran, 2022, Theranostics.

The oncogenic potential of a prostate cancer‐derived androgen receptor mutant

C. Tepper, H. Kung, R. deVere White, 2007, The Prostate.

Molecular alterations associated with LNCaP cell progression to androgen independence

J. Gregg, C. Tepper, H. Kung, 2004, The Prostate.

A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer

Steven B. Neuhauser, Stephen C. Grubb, Michael W. Lloyd, 2022, bioRxiv.

Use of RNA-Seq and a Transgenic Mouse Model to Identify Genes Which May Contribute to Mutant p53-Driven Prostate Cancer Initiation

A. Borowsky, C. Tepper, R. Vinall, 2022, Biology.

Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis

F. Azuaje, C. Tepper, R. Bjerkvig, 2019, Acta Neuropathologica Communications.

PERIOD 2 regulates low-dose radioprotection via PER2/pGSK3β/β-catenin/Per2 loop

C. Tepper, L. Fu, A. Vaughan, 2022, iScience.

Microdose-Induced Drug–DNA Adducts as Biomarkers of Chemotherapy Resistance in Humans and Mice

Susan Airhart, Ralph de Vere White, Karim Chamie, 2016, Molecular Cancer Therapeutics.

KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation

C. Tepper, H. Kung, Hong-Wu Chen, 2010, Proceedings of the National Academy of Sciences.

Genome-wide analysis of androgen receptor binding and gene regulation in two CWR22-derived prostate cancer cell lines.

Michael D. George, C. Tepper, H. Kung, 2010, Endocrine-related cancer.

Genome-wide analysis of androgen receptor binding and gene regulation in two CWR 22-derived prostate cancer cell lines

Michael D. George, C. Tepper, H. Kung, 2010 .

An androgen-regulated miRNA suppresses Bak1 expression and induces androgen-independent growth of prostate cancer cells

Christopher P Evans, C. Tepper, H. Kung, 2007, Proceedings of the National Academy of Sciences.

Development and Characterization of Bladder Cancer Patient-Derived Xenografts for Molecularly Guided Targeted Therapy

C. Bult, E. Liu, C. Tepper, 2015, PloS one.

KSHV transactivator-derived small peptide traps coactivators to attenuate MYC and inhibits leukemia and lymphoma cell growth

C. Tepper, M. Shimoda, J. Tuscano, 2021, Communications Biology.

ZIC2 Is Essential for Maintenance of Latency and Is a Target of an Immediate Early Protein during Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation

C. Tepper, Y. Izumiya, Ryan R. Davis, 2017, Journal of Virology.

Biphasic Euchromatin-to-Heterochromatin Transition on the KSHV Genome Following De Novo Infection

C. Tepper, H. Kung, Jae U. Jung, 2013, PLoS pathogens.

Profiling of gene expression changes caused by p53 gain‐of‐function mutant alleles in prostate cancer cells

J. Gregg, C. Tepper, H. Kung, 2005, The Prostate.

Cellular and molecular signatures of androgen ablation of prostate cancer

C. Tepper, H. Kung, 2009 .

A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth.

Zhiyong Guo, C. Tepper, J. Melamed, 2009, Cancer research.

MicroRNAs and their potential for translation in prostate cancer.

C. Tepper, R. deVere White, R. Vinall, 2009, Urologic oncology.

ARVib suppresses growth of advanced prostate cancer via inhibition of androgen receptor signaling

C. Tepper, Pui-Kai Li, C. Evans, 2021, Oncogene.

On the Origins of the Androgen Receptor Low Molecular Weight Species

C. Tepper, M. Mudryj, 2013, Hormones and Cancer.

Modeling Truncated AR Expression in a Natural Androgen Responsive Environment and Identification of RHOB as a Direct Transcriptional Target

Hui-Chi Tsai, C. Tepper, H. Kung, 2012, PloS one.

Molecular Targeting of Prostate Cancer During Androgen Ablation: Inhibition of CHES1/FOXN3

C. Tepper, 2010 .

Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells.

C. Tepper, H. Shih, H. Kung, 2006, Cancer research.

Modulation of caspase-8 and FLICE-inhibitory protein expression as a potential mechanism of Epstein-Barr virus tumorigenesis in Burkitt's lymphoma.

M. Seldin, C. Tepper, 1999, Blood.

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Yvonne A. Evrard, Michael W. Lloyd, Jeffrey H. Chuang, 2021, Nature Genetics.

Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity.

A. Bielawska, Y. Hannun, M. Seldin, 1995, Proceedings of the National Academy of Sciences of the United States of America.

ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2.

R. Cardiff, A. Borowsky, C. Tepper, 2010, Cancer research.

Syngeneic mouse mammary carcinoma cell lines: Two closely related cell lines with divergent metastatic behavior

J. Gregg, R. Cardiff, J. Hodgson, 2005, Clinical & Experimental Metastasis.

Capture Hi-C: Characterization of chromatin contacts

C. Tepper, Y. Izumiya, Ryan R. Davis, 2020, Epigenetics Methods.

Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence.

C. Tepper, H. Kung, D. Asmuth, 2007, Cancer research.

Reprogramming metabolism by histone methyltransferase NSD2 drives endocrine resistance via coordinated activation of pentose phosphate pathway enzymes.

O. Fiehn, L. Murphy, A. Borowsky, 2016, Cancer letters.

Inappropriate activation of the androgen receptor by nonsteroids: involvement of the Src kinase pathway and its therapeutic implications.

C. Tepper, H. Kung, Hong-Wu Chen, 2006, Cancer research.

The R273H p53 mutation can facilitate the androgen-independent growth of LNCaP by a mechanism that involves H2 relaxin and its cognate receptor LGR7

C. Tepper, R. Gandour-Edwards, R. Vinall, 2006, Oncogene.

Obatoclax, a BH3 Mimetic, Enhances Cisplatin-Induced Apoptosis and Decreases the Clonogenicity of Muscle Invasive Bladder Cancer Cells via Mechanisms That Involve the Inhibition of Pro-Survival Molecules as Well as Cell Cycle Regulators

C. Tepper, P. Ghosh, R. Vinall, 2019, International journal of molecular sciences.

Short-term organoid culture for drug sensitivity testing of high-grade serous carcinoma.

K. Gotimer, L. Smith, C. Tepper, 2020, Gynecologic oncology.

Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis

F. Azuaje, C. Tepper, R. Bjerkvig, 2019, Acta neuropathologica communications.

Histone Methyltransferase NSD2/MMSET Mediates Constitutive NF-κB Signaling for Cancer Cell Proliferation, Survival, and Tumor Growth via a Feed-Forward Loop

C. Tepper, Ping Yang, H. Kung, 2012, Molecular and Cellular Biology.

Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells.

A. Chinnaiyan, C. Tepper, R. Mehra, 2010, Cancer research.

Nrdp 1-Mediated Regulation of ErbB 3 Expression by the Androgen Receptor in Androgen-Dependent but not Castrate-Resistant Prostate Cancer Cells

A. Chinnaiyan, C. Tepper, R. Mehra, 2010 .

The Androgen Receptor is a negative regulator of eIF4E Phosphorylation at S209: Implications for the use of mTOR inhibitors in advanced prostate cancer

C. Tepper, R. deVere White, P. Ghosh, 2017, Oncogene.

KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC

C. Tepper, H. Kung, Cheng-Ying Chu, 2018, Oncogene.

Microarray analysis reveals potential target genes of NF‐κB2/p52 in LNCaP prostate cancer cells

C. Tepper, A. Gao, N. Nadiminty, 2010, The Prostate.

Tumor suppressive miR-124 targets androgen receptor and inhibits proliferation of prostate cancer cells

C. Tepper, H. Kung, R. Gandour-Edwards, 2013, Oncogene.

The Phosphatidylinositol 3-Kinase Pathway as a Potential Therapeutic Target in Bladder Cancer

C. Tepper, R. deVere White, S. Airhart, 2017, Clinical Cancer Research.

Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent

R. Cardiff, R. Schreiber, A. Borowsky, 2015, PloS one.

Androgen receptor-dependent regulation of metabolism in high grade bladder cancer cells

C. Tepper, G. Cortopassi, P. Ghosh, 2023, Scientific Reports.

Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome

C. Tepper, B. Arzi, W. Murphy, 2017, Stem Cell Research & Therapy.

A Syngeneic ErbB2 Mammary Cancer Model for Preclinical Immunotherapy Trials

A. Borowsky, C. Tepper, Zsófia Pénzváltó, 2019, Journal of Mammary Gland Biology and Neoplasia.

KSHV episomes reveal dynamic chromatin loop formation with domain-specific gene regulation

C. Tepper, M. Fujimuro, B. Durbin-Johnson, 2018, Nature Communications.

GCP‐mediated growth inhibition and apoptosis of prostate cancer cells via androgen receptor‐dependent and ‐independent mechanisms

C. Tepper, P. Mack, R. Vinall, 2007, The Prostate.

KSHV Episome Tethering Sites on Host Chromosomes: Regulation of Latency-Lytic Switch by the ChAHP complex

Frank Y. S. Chuang, C. Tepper, M. Salemi, 2021 .

KSHV Topologically Associating Domains in Latent and Reactivated Viral Chromatin

C. Tepper, Y. Izumiya, Chanikarn Chantarasrivong, 2022, bioRxiv.

Tyrosine Kinases and Cellular Signaling in Prostate Cancer

C. Tepper, H. Kung, R. D. White, 2001 .

Dual Blockade of PKA and NF–κB Inhibits H2 Relaxin-Mediated Castrate-Resistant Growth of Prostate Cancer Sublines and Induces Apoptosis

C. Tepper, R. Gandour-Edwards, P. Ghosh, 2011, Hormones & cancer.

Inappropriate activation of androgen receptor by relaxin via beta-catenin pathway.

C. Tepper, H. Kung, R. deVere White, 2008, Oncogene.

miR‐125b promotes growth of prostate cancer xenograft tumor through targeting pro‐apoptotic genes

C. Tepper, H. Kung, R. D. White, 2011, The Prostate.

Novel Patient Metastatic Pleural Effusion-Derived Xenograft Model of Renal Medullary Carcinoma Demonstrates Therapeutic Efficacy of Sunitinib

L. Beckett, C. Tepper, R. Gandour-Edwards, 2021, Frontiers in Oncology.

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation

A. Borowsky, C. Tepper, W. Murphy, 2018, Theranostics.

Identification of integrin drug targets for 17 solid tumor types

Adith S. Arun, K. Lam, C. Tepper, 2018, Oncotarget.

Regulation of Id1 expression by SRC: implications for targeting of the bone morphogenetic protein pathway in cancer.

C. Tepper, D. Gandara, H. Kung, 2008, Cancer research.

Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes.

J. Gregg, C. Tepper, N. C. Schanen, 2006, Human molecular genetics.

Proteostasis by STUB1/HSP70 complex controls sensitivity to androgen receptor targeted therapy in advanced prostate cancer

C. Tepper, M. Dall’Era, Liangren Liu, 2018, Nature Communications.

The essential roles of FXR in diet and age influenced metabolic changes and liver disease development: a multi-omics study

C. Tepper, C. Slupsky, Lili Sheng, 2023, Biomarker Research.

The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi’s sarcoma associated herpesvirus reactivation

Mel Campbell, Wen-Ping Hsieh, Chia-Han Chu, 2013, BMC Genomics.

miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src.

C. Tepper, H. Kung, R. deVere White, 2015, Cancer research.

E2F1 expression in LNCaP prostate cancer cells deregulates androgen dependent growth, suppresses differentiation, and enhances apoptosis

C. Tepper, D. Asmuth, M. Mudryj, 2006, The Prostate.

Molecular analysis of metastasis in a polyomavirus middle T mouse model: the role of osteopontin

J. Gregg, R. Cardiff, L. Young, 2004, Breast Cancer Research.

KSHV uses viral IL6 to expand infected immunosuppressive macrophages

C. Tepper, M. Shimoda, E. Maverakis, 2023, bioRxiv.

Prolonged Kaposi's Sarcoma-associated Herpesvirus vIL-6 Exposure 1 Enhances Inflammatory Responses by Epigenetic Reprogramming 2 3

C. Tepper, H. Katano, M. Shimoda, 2023 .

Mitochondrial nucleic acids as internal standards for blot hybridization analyses.

C. Tepper, G. P. Studzinski, M. M. Pater, 1992, Analytical biochemistry.

Supporting Online Material Recombinant Origin of the Retrovirus Xmrv

V. Pathak, Wei-Shau Hu, J. Levy, 2022 .

KSHV vIL-6 Enhances Inflammatory Responses by Epigenetic Reprogramming

C. Tepper, H. Katano, M. Shimoda, 2023, bioRxiv.

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Steven B. Neuhauser, Yvonne A. Evrard, Michael W. Lloyd, 2019, Nature Genetics.

PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery

Yvonne A. Evrard, David M. Rocke, Jessica J. Andrews, 2022, NAR cancer.

The JAX patient-derived xenograft program: A unique resource to advance genome-guided cancer medicine and therapeutic agent testing.

Jeffrey H. Chuang, C. Bult, J. George, 2014 .

Is Essential for of and Is a Target of an Immediate Early Protein during Kaposi's Sarcoma-Associated Herpesvirus Lytic Reactivation.

C. Tepper, M. Campbell, Yuanzhi Lyu, 2017 .

MicroRNA expression analysis of human skin fibroblasts treated with high‐fluence light‐emitting diode‐red light

C. Tepper, A. Mamalis, J. Jagdeo, 2019, Journal of biophotonics.

miR-124 and Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src.

C. Tepper, H. Kung, R. deVere White, 2015, Cancer research.

ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2.

R. Cardiff, A. Borowsky, C. Tepper, 2010, Cancer research.

Histone Demethylase JMJD2A Regulates Kaposi's Sarcoma-Associated Herpesvirus Replication and Is Targeted by a Viral Transcriptional Factor

K. Lam, C. Tepper, H. Kung, 2011, Journal of Virology.

High frequency of the PNPLA3 rs738409 [G] single‐nucleotide polymorphism in Hmong individuals as a potential basis for a predisposition to chronic liver disease

D. M. Fang, Moon S. Chen, J. Gregg, 2018, Cancer.

Multiomic analysis for optimization of combined focal and immunotherapy protocols in murine pancreatic cancer

Aaron M. Newman, S. Aviran, C. Tepper, 2022, Theranostics.

Title High frequency of the PNPLA 3 rs 738409 [ G ] single-nucleotide polymorphism in Hmong individuals as a potential basis for a predisposition to chronic liver disease Permalink

D. M. Fang, J. Gregg, C. Tepper, 2018 .

Post-death Vesicles of Senescent Bone Marrow Mesenchymal Stromal Polyploids Promote Macrophage Aging and Breast Cancer

C. Tepper, A. Monjazeb, Li-En Jao, 2024, bioRxiv.