C. Blake

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Molecular Structure of a Fibrillar Alzheimer's Aβ Fragment†

L. Serpell, C. Blake, P. Fraser, 2000 .

Structure of prealbumin: secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 A.

S J Oatley, C. Blake, M. Geisow, 1977, Journal of molecular biology.

Sequence, structure and activity of phosphoglycerate kinase: a possible hinge-bending enzyme

P. Evans, D. Rice, C. Blake, 1979, Nature.

Human lysozyme gene mutations cause hereditary systemic amyloidosis

D. Booth, C. Blake, M. Pepys, 1993, Nature.

Structure of hen egg-white lysozyme. A three-dimensional Fourier synthesis at 2 Angstrom resolution.

D. F. Koenig, D. Phillips, A. North, 1965, Nature.

Structure of Hen Egg-White Lysozyme: A Three-dimensional Fourier Synthesis at 2 Å Resolution

D. F. Koenig, D. Phillips, A. North, 1965, Nature.

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

L. Serpell, C. Blake, P. Fraser, 1997, Journal of molecular biology.

Refinement of human lysozyme at 1.5 A resolution analysis of non-bonded and hydrogen-bond interactions.

P J Artymiuk, P. Artymiuk, C. Blake, 1981, Journal of molecular biology.

Do genes-in-pieces imply proteins-in-pieces?

C. Blake, C. C. F. Blake, 1978, Nature.

Strjcture of human plasma prealbumin at 2-5 A resolution. A preliminary report on the polypeptide chain conformation, quaternary structure and thyroxine binding.

C. Blake, M. Geisow, B. Rérat, 1974, Journal of molecular biology.

The fifteenth Douglas Lea lecture: X-ray studies of protein-DNA-hormone interactions.

C. Blake, 1978, Physics in medicine and biology.

Molecular mechanisms of fibrillogenesis and the protective role of amyloid P component: two possible avenues for therapy.

S. Radford, D. Booth, C. Robinson, 1996, Ciba Foundation symposium.

Crystalline cis-benzene glycol dehydrogenase from Pseudomonas putida.

P. Artymiuk, C. Blake, P. Geary, 1977, Journal of molecular biology.

Exon and domain evolution in the proenzymes of blood coagulation and fibrinolysis.

C. Blake, K. Harlos, S. Holland, 1987, Cold Spring Harbor symposia on quantitative biology.

How the structure of lysozyme was actually determined

D. F. Koenig, L. Johnson, D. Phillips, 2006 .

S-S bridges of cathepsin B and H from bovine spleen: a basis for cathepsin B model building and possible functional implications for discrimination between exo- and endopeptidase activities among cathepsins B, H and L.

B. Meloun, V. Kostka, C. Blake, 1991, Biomedica biochimica acta.

The compact domain conformation of human Glu-plasminogen in solution.

C. Ponting, C. Blake, G. Spraggon, 1992, Biochimica et biophysica acta.

Preliminary X-ray investigation of enzyme substrate complexes of horse muscle phosphoglycerate kinase.

D. Rice, C. Blake, 1984, Journal of molecular biology.

X-Ray Investigation of Fragment 1 of Bovine Prothrombin

C. Blake, M. Esnouf, M. Esnouf, 1977, Thrombosis and Haemostasis.

Preliminary crystallographic data on human lysozyme.

C. Blake, E. Osserman, I. Swan, 1969, Journal of molecular biology.

Deriving the generic structure of the fibronectin type II domain from the prothrombin Kringle 1 crystal structure.

C. Blake, K. Harlos, S. Holland, 1987, The EMBO journal.

A crystallographic study of the oxidation of lysozyme by iodine

C. Blake, 1967, Proceedings of the Royal Society of London. Series B. Biological Sciences.

The structure and function of methanol dehydrogenase and related quinoproteins containing pyrrolo-quinoline quinone.

C. Blake, C. Anthony, M. Ghosh, 1994, The Biochemical journal.

MOLECULAR INTERACTIONS OF TOXIC CHLORINATED DIBENZO-P-DIOXINS AND DIBENZOFURANS WITH THYROXINE BINDING PREALBUMIN

C. Blake, K. Chae, S. Oatley, 1985 .

On the conformation of the hen egg-white lysozyme molecule

D. Phillips, A. North, C. Blake, 1967, Proceedings of the Royal Society of London. Series B. Biological Sciences.

Proteins, exons and molecular evolution.

C. Blake, S K Holland, C C Blake, 1987, Bio Systems.

Crystal structure of manganese superoxide dismutase from Bacillus stearothermophilus at 2.4 A resolution.

C. Blake, M. Parker, 1988, Journal of molecular biology.

Crystallographic studies of the activity of hen egg-white lysozyme

A. North, C. Blake, G. Mair, 1967, Proceedings of the Royal Society of London. Series B. Biological Sciences.

A "helix-scissors" mechanism for the hinge-bending conformational change in phosphoglycerate kinase.

F. Cohen, D. Rice, C. Blake, 2009, International journal of peptide and protein research.

X‐ray enzymology

C. Blake, 1976, FEBS letters.

Protein–DNA and protein–hormone interactions in prealbumin: a model of the thyroid hormone nuclear receptor?

C. Blake, S. Oatley, C. C. F. Blake, 1977, Nature.

Iron‐ and manganese‐containing superoxide dismutases can be distinguished by analysis of their primary structures

C. Blake, M. Parker, 1988, FEBS letters.

Physical and chemical properties of lysozyme.

C. Dobson, L. Johnson, D. Phillips, 1977, Ciba Foundation symposium.

The crystal structure of benzamide

C. Blake, R. Small, 1972 .

Structure Of Lysozyme: A Fourier Map of the Electron Density at 6 Å Resolution obtained by X-ray Diffraction

A. North, C. Blake, R. Poljak, 1962, Nature.

The preparation of isomorphous derivatives.

C. Blake, Colin C.F. Blake, 1968, Advances in protein chemistry.

An x-ray study of the subunit structure of prealbumin.

C. Blake, B. Rérat, C. Rérat, 1971, Journal of molecular biology.

Structure of horse muscle phosphoglycerate kinase. Some results on the chain conformation, substrate binding and evolution of the molecule from a 3 angstrom Fourier map.

P R Evans, P. Evans, C. Blake, 1974, Journal of molecular biology.

Exons and the evolution of proteins.

C. Blake, 1985, International review of cytology.

Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain.

A. Michelson, C. Blake, S. Orkin, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Amyloid Precursor Protein

C. Blake, 2002 .

Structure of Met30 variant of transthyretin and its amyloidogenic implications.

Y. Sakaki, C. Blake, P. Matias, 1993, The EMBO journal.

The refined structure of the quinoprotein methanol dehydrogenase from Methylobacterium extorquens at 1.94 A.

C. Blake, C. Anthony, K. Harlos, 1995, Structure.

Exons and the evolution of proteins

C. Blake, 1983 .

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

Christopher M. Dobson, Sheena E. Radford, Carol V. Robinson, 1997, Nature.

Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous β-sheet helix

Louise C. Serpell, L. Serpell, C. Blake, 1996 .

Studies on the Molecular Arrangement in Transthyretin-Related Familial Amyloidotic Polyneuropathy Fibrils

C. Blake, C. Terry, 1991 .

The active site of methanol dehydrogenase contains a disulphide bridge between adjacent cysteine residues

C. Blake, C. Anthony, K. Harlos, 1994, Nature Structural Biology.

Structure and binding properties of hen lysozyme modified at tryptophan 62.

C. Dobson, R. J. Williams, C. Blake, 1981, Journal of molecular biology.

An x-ray study of the structure and binding properties of iodine-inactivated lysozyme.

C. Beddell, C. Blake, S. Oatley, 1975, Journal of molecular biology.

Molecular biology: Exons — present from the beginning?

C. Blake, 1983, Nature.

From the globular to the fibrous state: protein structure and structural conversion in amyloid formation

C. Blake, M. Sunde, C C Blake, 1998, Quarterly Reviews of Biophysics.

The molecular basis of amyloidosis

L. Serpell, C. Blake, M. Sunde, 1997, Cellular and Molecular Life Sciences CMLS.

The structure of amyloid fibrils by electron microscopy and X-ray diffraction.

C. Blake, M. Sunde, C Blake, 1997, Advances in protein chemistry.

Exons and the structure, function and evolution of haemoglobin

C. Blake, 1981, Nature.

Genes pieced together — exons delineate homologous structures of diverged lysozymes

A. E. Sippel, P. Artymiuk, C. Blake, 1981, Nature.

The crystal structure of tortoise egg-white lysozyme at 6 A resolution.

C. Blake, R. Keegan, R. Aschaffenburg, 1980, Biochimica et biophysica acta.

Crystallographic studies of the dynamic properties of lysozyme

D. Phillips, P. Artymiuk, C. Blake, 1979, Nature.

6 – The High Resolution X-Ray Study of Human Lysozyme: A Preliminary Analysis

C. Blake, I. Swan, S. Banyard, 1974 .

X-ray analysis of structure of human lysozyme at 6 A resolution.

C. Blake, I. Swan, 1971, Nature: New biology.

The Structure and Function of Lysozyme

C. Blake, 1969 .

Exons encode protein functional units

C. Blake, C. C. F. Blake, 1979, Nature.

X-ray studies of water in crystals of lysozyme.

P. Artymiuk, C. Blake, W. Pulford, 1983, Journal of molecular biology.

Structure and order of the protein and carbohydrate domains of prothrombin fragment 1

C. Blake, K. Harlos, M. Esnouf, 1987, FEBS letters.

Molecular structure of a fibrillar Alzheimer's A beta fragment.

L. Serpell, C. Blake, P. Fraser, 2000, Biochemistry.

The enzymes of glycolysis: structure, activity and evolution.

H. Watson, D. Phillips, C. Blake, 1981, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Predicting a membrane protein

C. Blake, 1980, Nature.

Review Lecture - Prealbumin and the thyroid hormone nuclear receptor

C. Blake, 1981, Proceedings of the Royal Society of London. Series B. Biological Sciences.

The crystal structure of transthyretin from chicken.

C. Blake, M. Sunde, S. Richardson, 1996, European journal of biochemistry.

The "edge strand" hypothesis: Prediction and test of a mutational "hot-spot" on the transthyretin molecule associated with FAP amyloidogenesis

L. Serpell, C. Blake, I. Dacklin, 1996 .

X-ray analysis of thyroid hormone binding to prealbumin.

C. Blake, S. Oatley, J. Burridge, 1978, Biochemical Society transactions.

Structure of Horse-muscle Phosphoglycerate Kinase at 6 Å Resolution

P. Evans, C. Blake, R. Scopes, 1972 .

Crystallization and preliminary crystallographic study of cathepsin D inhibitor from potatoes.

V. Kostka, C. Blake, K. Harlos, 1991, Journal of molecular biology.

Examination of the structure of the transthyretin amyloid fibril by image reconstruction from electron micrographs.

P E Fraser, E P Morris, L. Serpell, 1995, Journal of molecular biology.

The Structures of the Monoclinic and Orthorhombic Forms of Hen Egg-White Lysozyme at 6 Angstroms Resolution

Peter J. Artymiuk, K. S. Wilson, David W. Rice, 1981 .

Molecular mechanics simulation of protein-ligand interactions: binding of thyroid hormone analogs to prealbumin

Peter A. Kollman, Paul K. Weiner, Jeffrey M. Blaney, 1982 .

Structural identity between the iron- and manganese-containing superoxide dismutases.

J. V. Bannister, C. Blake, M. Parker, 1987, Protein engineering.

A molecular model of the amyloid fibril.

L. Serpell, C. Blake, M. Sunde, 1996, Ciba Foundation symposium.

X-ray structure of PQQ-dependent methanol dehydrogenase.

C. Blake, C. Anthony, K. Harlos, 1994, EXS.

X-ray studies of crystalline proteins.

C. Blake, 1972, Progress in biophysics and molecular biology.

Phosphoglycerate kinase.

D W Rice, D. Rice, C. Blake, 1981, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Molecular interactions of toxic chlorinated dibenzo-p-dioxins and dibenzofurans with thyroxine binding prealbumin.

C. Blake, K. Chae, S. Oatley, 1985, Journal of medicinal chemistry.

Synchrotron X-ray studies suggest that the core of the transthyretin amyloid fibril is a continuous beta-sheet helix.

L. Serpell, C. Blake, C Blake, 1996, Structure.

Crystallographic study of the interaction of urea with lysozyme

D. Koshland, R. Tjian, C. Blake, 1974, Nature.

Crystallization and preliminary crystallographic investigation of methanol dehydrogenase from Methylobacterium extorquens AM1.

C. Blake, C. Anthony, K. Harlos, 1992, Journal of molecular biology.

The nucleotide-binding fold revisited

C. Blake, 1977, Nature.

Evolution of nucleotide-binding proteins

C. Blake, 1974, Nature.

Structurally specific binding of halogenated biphenyls to thyroxine transport protein.

C. Blake, S. Oatley, U. Rickenbacher, 1986, Journal of medicinal chemistry.

The trouble with kinase crystals

C. Blake, 1978, Nature.

Chemical aspects of protein crystallography.

C. Blake, 1975, Biochimie.

Exons--present from the beginning?

C. Blake, 1983, Nature.

X-ray cryoenzymology

C. Blake, 1976, Nature.

Tail-wagging antibodies?

C. Blake, 1976, Nature.

Computer graphics in drug design: molecular modeling of thyroid hormone-prealbumin interactions.

J M Burridge, J M Blaney, R Langridge, 1982, Journal of medicinal chemistry.

Antibody structure and antigen binding

C. Blake, 1975, Nature.

X-RAY CRYSTALLOGRAPHIC STUDIES OF THYROID HORMONE, ANALOGUE AND COMPETITOR BINDING INTERACTIONS WITH HUMAN SERUM PREALBUMIN

C. Blake, S. Oatley, J. Burridge, 1982 .

Structure of horse-muscle phosphoglycerate kinase at 6 angstrom resolution.

P. Evans, C. Blake, R. Scopes, 1972, Nature: New biology.