J. Kuret

发表

Evidence for an intermediate in tau filament formation.

C. Chirita, J. Kuret, 2004, Biochemistry.

Research towards tau imaging.

Jeff Kuret, J. Kuret, K. Cisek, 2011, Journal of Alzheimer's disease : JAD.

Triggers of full-length tau aggregation: a role for partially folded intermediates.

C. Chirita, J. Kuret, E. Congdon, 2005, Biochemistry.

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

Molecular Interactions among Protein Phosphatase 2A, Tau, and Microtubules

G. Bloom, J. Kuret, M. Mumby, 1999, The Journal of Biological Chemistry.

Structure-activity relationship of cyanine tau aggregation inhibitors.

J. Kuret, K. Duff, E. Congdon, 2009, Journal of medicinal chemistry.

Computational integration of nanoscale physical biomarkers and cognitive assessments for Alzheimer’s disease diagnosis and prognosis

J. Kuret, D. Scharre, Z. Fan, 2017, Science Advances.

Adenohypophyseal hormones and related substances

J. Kuret, F. Murad, 1990 .

Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1.

J. Kuret, A. Vancura, Pinfei Wang, 1992, Molecular biology of the cell.

Budding and fission yeast casein kinase I isoforms have dual-specificity protein kinase activity.

T. Hunter, J. Kuret, M. Hoekstra, 1994, Molecular biology of the cell.

Casein kinase 1 delta is associated with pathological accumulation of tau in several neurodegenerative diseases

J. Kuret, P. Mcgeer, N. Ghoshal, 2000, Neurobiology of Aging.

Progranulin expression is upregulated after spinal contusion in mice

J. Kuret, P. Popovich, S. Kostyk, 2009, Acta Neuropathologica.

Hyperphosphorylation Renders Tau Prone to Aggregate and to Cause Cell Death

Hye Kyong Kweon, P. Andrews, J. Kuret, 2020, Molecular Neurobiology.

Tau Is Modified by Tissue Transglutaminase In Situ: Possible Functional and Metabolic Effects of Polyamination

J. Kuret, G. Johnson, J. Tucholski, 1999, Journal of neurochemistry.

A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease.

J. Kuret, E. Cochran, J. Smiley, 1999, The American journal of pathology.

Cross‐Linking Sites of the Human Tau Protein, Probed by Reactions with Human Transglutaminase

L. Lorand, J. Kuret, S. Prasanna Murthy, 1998, Journal of neurochemistry.

Transient expression of fluorescent tau proteins promotes process formation in PC12 cells: Contributions of the tau C‐terminus to this process

J. Kuret, M. Rasenick, Jiang-Zhou Yu, 2002, Journal of neuroscience research.

Prenylated isoforms of yeast casein kinase I, including the novel Yck3p, suppress the gcs1 blockage of cell proliferation from stationary phase

G. C. Johnston, J. Kuret, M. Hoekstra, 1996, Molecular and cellular biology.

Structure-activity relationship of cyclic thiacarbocyanine tau aggregation inhibitors.

J. Kuret, K. Cisek, D. Churchill, 2011, Bioorganic & medicinal chemistry letters.

AFLUID July 46/1

F. Murad, J. Kuret, L. Binder, 1999 .

QSAR studies for prediction of cross-β sheet aggregate binding affinity and selectivity.

J. Kuret, K. Cisek, 2012, Bioorganic & medicinal chemistry.

Structural Determinants of Tau Aggregation Inhibitor Potency*

J. Kuret, K. Cisek, K. Schafer, 2013, The Journal of Biological Chemistry.

Mutagenesis of the regulatory subunit of yeast cAMP-dependent protein kinase. Isolation of site-directed mutants with altered binding affinity for catalytic subunit.

J. Kuret, M. Zoller, K. E. Johnson, 1988, The Journal of biological chemistry.

Identification of the sites on rabbit skeletal muscle protein phosphatase inhibitor-2 phosphorylated by casein kinase-II.

P. Cohen, J. Kuret, C. Holmes, 1986, Biochimica et biophysica acta.

Identification of high levels of protein phosphatase‐1 in rat liver nuclei

P. Cohen, J. Kuret, H. Bell, 1986, FEBS letters.

Multisite phosphorylation of glycogen synthase from rabbit skeletal muscle. Identification of the sites phosphorylated by casein kinase-I.

P. Cohen, J. Woodgett, J. Kuret, 1982, European journal of biochemistry.

Islet Cells Grow after Transplantation of Fetal Pancreas and Control of Diabetes

J. Kuret, Y. Mullen, J. Brown, 1981, Diabetes.

Purification and characterization of C1, the catalytic subunit of Saccharomyces cerevisiae cAMP-dependent protein kinase encoded by TPK1.

S. Cameron, J. Kuret, L. Levin, 1988, The Journal of biological chemistry.

Wolframin is a novel regulator of tau pathology and neurodegeneration

L. Honig, F. Urano, J. Kuret, 2022, Acta Neuropathologica.

A solid-phase screen for protein kinase substrate selectivity.

J. Kuret, G. Carmel, 1992, Analytical biochemistry.

Structure and mechanism of action of tau aggregation inhibitors.

J. Kuret, K. Cisek, Carol J. Huseby, 2014, Current Alzheimer research.

Normal response to pregnancy in rats cured of streptozotocin diabetes by transplantation of one fetal pancreas

J. Kuret, Y. Mullen, J. Brown, 1982, Diabetologia.

Ca2+/calmodulin-dependent microtubule-associated protein 2 kinase: broad substrate specificity and multifunctional potential in diverse tissues.

H. Schulman, J. Kuret, K. Spitzer, 1985, Biochemistry.

Modulation and detection of tau aggregation with small-molecule ligands.

J. Kuret, J. R. Jensen, K. Funk, 2009, Current Alzheimer research.

Pseudophosphorylation of tau protein directly modulates its aggregation kinetics.

J. Kuret, K. Schafer, Sohee Kim, 2011, Biochimica et biophysica acta.

A prenylation motif is required for plasma membrane localization and biochemical function of casein kinase I in budding yeast.

J. Kuret, A. Vancura, B. Leichus, 1994, The Journal of biological chemistry.

Cytoplasmic forms of fission yeast casein kinase-1 associate primarily with the particulate fraction of the cell.

J. Kuret, G. Carmel, A. Vancura, 1994, The Journal of biological chemistry.

Expression, purification, crystallization, and preliminary x-ray analysis of casein kinase-1 from Schizosaccharomyces pombe.

B. Chait, J. Kuret, Xiaodong Cheng, 1994, The Journal of biological chemistry.

Cyanine dye N744 inhibits tau fibrillization by blocking filament extension: implications for the treatment of tauopathic neurodegenerative diseases.

C. Chirita, J. Kuret, M. Necula, 2005, Biochemistry.

Mechanism of autophosphorylation of the multifunctional Ca2+/calmodulin-dependent protein kinase.

H. Schulman, J. Kuret, H Schulman, 1985, The Journal of biological chemistry.

Purification and characterization of a Ca2+/calmodulin-dependent protein kinase from rat brain.

H. Schulman, J. Kuret, Jeff Kuret, 1984, Biochemistry.

A static laser light scattering assay for surfactant-induced tau fibrillization.

J. Kuret, M. Necula, Mihaela Necula, 2004, Analytical biochemistry.

A mutation in the catalytic subunit of cAMP-dependent protein kinase that disrupts regulation.

M. Wigler, S. Cameron, S. Powers, 1988, Science.

Structure of the unliganded cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae.

J. Kuret, J. Pflugrath, G. Carmel, 2001, Archives of biochemistry and biophysics.

Crystallization and preliminary X-ray analysis of the cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae.

J. Kuret, J. Pflugrath, 1991, Biochemistry.

Crystal Structure of a Conformation-selective Casein Kinase-1 Inhibitor*

Martin Egli, Jeff Kuret, Stephen C. Bergmeier, 2000, The Journal of Biological Chemistry.

Regulation of Phosphatidylinositol 4-Phosphate 5-Kinase fromSchizosaccharomyces pombe by Casein Kinase I*

J. Kuret, I. Vancurova, A. Vancura, 1999, The Journal of Biological Chemistry.

Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer's Disease.

Stefani N. Thomas, J. Kuret, A. Alonso, 2019, Journal of Alzheimer's disease : JAD.

Inhibition of Tau Polymerization with a Cyanine Dye in Two Distinct Model Systems*

J. Kuret, C. Conrad, Lili Wang, 2009, The Journal of Biological Chemistry.

Evaluating triggers and enhancers of tau fibrillization

J. Kuret, E. Congdon, Haishan Yin, 2005, Microscopy research and technique.

A theoretical study of polymorphism in VQIVYK fibrils.

S. J. Singer, J. Kuret, Mithila V Agnihotri, 2021, Biophysical journal.

Granulovacuolar degeneration (GVD) bodies of Alzheimer's disease (AD) resemble late‐stage autophagic organelles

J. Kuret, R. Mrak, K. Funk, 2011, Neuropathology and applied neurobiology.

Lysosomal Fusion Dysfunction as a Unifying Hypothesis for Alzheimer's Disease Pathology

J. Kuret, K. Funk, 2012, International journal of Alzheimer's disease.

Membrane-specific spin trap, 5-dodecylcarbamoyl-5-N-dodecylacetamide-1-pyroline-N-oxide (diC12PO): theoretical, bioorthogonal fluorescence imaging and EPR studies.

J. Zweier, J. Kuret, F. Villamena, 2019, Organic & biomolecular chemistry.

Ligand polarizability contributes to tau fibril binding affinity.

J. Kuret, K. Cisek, J. R. Jensen, 2011, Bioorganic & medicinal chemistry.

Casein Kinase 1 Delta Phosphorylates Tau and Disrupts Its Binding to Microtubules*

J. Kuret, Haishan Yin, Guibin Li, 2004, Journal of Biological Chemistry.

Casein kinase 1 delta mRNA is upregulated in Alzheimer disease brain

J. Kuret, P. Mcgeer, E. Mcgeer, 2000, Brain Research.

Casein Kinase 1 Is Tightly Associated with Paired‐Helical Filaments Isolated from Alzheimer's Disease Brain

J. Kuret, M. Hoekstra, A. Demaggio, 1997, Journal of neurochemistry.

Direct cellular delivery of human proteasomes to delay tau aggregation

Min Jae Lee, Won Hoon Choi, J. Kuret, 2014, Nature Communications.

C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease.

J. Kuret, R. Berry, V. Cryns, 2000, Journal of cell science.

Casein kinase-1 isoforms differentially associate with neurofibrillary and granulovacuolar degeneration lesions

J. Kuret, D. Vandré, Haiyang Tao, 2006, Acta Neuropathologica.

Small-Molecule Mediated Neuroprotection in an In Situ Model of Tauopathy

J. Kuret, G. Hall, A. Abraha, 2009, Neurotoxicity Research.

Casein kinase 1 alpha associates with the tau-bearing lesions of inclusion body myositis

Jeff Kuret, J. Mendell, J. Kuret, 2008, Neuroscience Letters.

Tau Aggregation and Toxicity in a Cell Culture Model of Tauopathy*

J. Kuret, Haishan Yin, Guibin Li, 2007, Journal of Biological Chemistry.

Structural basis for selectivity of the isoquinoline sulfonamide family of protein kinase inhibitors.

J. Kuret, G. Carmel, X. Cheng, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Pseudophosphorylation and Glycation of Tau Protein Enhance but Do Not Trigger Fibrillization in Vitro*

J. Kuret, M. Necula, Mihaela Necula, 2004, Journal of Biological Chemistry.

Electron microscopy as a quantitative method for investigating tau fibrillization.

J. Kuret, M. Necula, Mihaela Necula, 2004, Analytical biochemistry.

The role of annealing and fragmentation in human tau aggregation dynamics

R. Bundschuh, J. Kuret, Carol J. Huseby, 2019, The Journal of Biological Chemistry.

Differential Assembly of Human Tau Isoforms in the Presence of Arachidonic Acid

Jeff Kuret, J. Kuret, L. Binder, 2000, Journal of neurochemistry.

Differentiating Alzheimer disease-associated aggregates with small molecules

Wenwei Huang, James Inglese, Jeff Kuret, 2007, Neurobiology of Disease.

Granulovacuolar degeneration bodies of Alzheimer's disease resemble late‐stage autophagic organelles

J. Kuret, R. Mrak, K. Funk, 2011 .

Tau aggregation and toxicity in tauopathic neurodegenerative diseases.

J. Kuret, N. Honson, 2008, Journal of Alzheimer's disease : JAD.

Tau Isoform Composition Influences Rate and Extent of Filament Formation*

H. Nagaraja, J. Kuret, E. Congdon, 2012, The Journal of Biological Chemistry.

Pathways of tau fibrillization.

C. Chirita, J. Kuret, E. Congdon, 2005, Biochimica et biophysica acta.

The Structural Basis of Monoclonal Antibody Alz50's Selectivity for Alzheimer's Disease Pathology*

J. Kuret, E. Mager, L. Binder, 1996, The Journal of Biological Chemistry.

Crystal structure of casein kinase‐1, a phosphate‐directed protein kinase.

R M Sweet, J. Kuret, R. Sweet, 1995, The EMBO journal.

Two motifs within the tau microtubule‐binding domain mediate its association with the hsc70 molecular chaperone

Jeff Kuret, J. Kuret, Gloria Lee, 2008, Journal of neuroscience research.

C‐terminal truncation modulates both nucleation and extension phases of τ fibrillization

J. Kuret, Haishan Yin, 2006, FEBS letters.

In vitro polymerization of tau protein monitored by laser light scattering: method and application to the study of FTDP-17 mutants.

J. Kuret, R. Berry, M. Vitek, 2000, Biochemistry.

Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity.

Stefani N. Thomas, J. Kuret, A. Yang, 2014, The Biochemical journal.

Dual modification of Alzheimer’s disease PHF-tau protein by lysine methylation and ubiquitylation: a mass spectrometry approach

Stefani N. Thomas, J. Kuret, P. Davies, 2011, Acta Neuropathologica.

Tau‐66: evidence for a novel tau conformation in Alzheimer's disease

L. Beckett, J. Kuret, E. Mufson, 2001, Journal of neurochemistry.

Nucleation-dependent Tau Filament Formation

Anastasios Matzavinos, Jeff Kuret, J. Kuret, 2008, Journal of Biological Chemistry.

Potency of a tau fibrillization inhibitor is influenced by its aggregation state.

J. Kuret, E. Congdon, M. Necula, 2007, Archives of biochemistry and biophysics.

Site‐specific pseudophosphorylation modulates the rate of tau filament dissociation

J. Kuret, M. Necula, 2005, FEBS letters.

Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps

H. Nagaraja, J. Kuret, Haishan Yin, 2008, Journal of neurochemistry.

New directions for frontotemporal dementia drug discovery

J. Trojanowski, H. Fillit, W. Koroshetz, 2008, Alzheimer's & Dementia.

Identification of gene networks mediating regional resistance to tauopathy in late-onset Alzheimer’s disease

J. Kuret, Christopher A. Ayoub, Connor S Wagner, 2023, PLoS genetics.

Ligand-dependent inhibition and reversal of tau filament formation.

C. Chirita, J. Kuret, M. Necula, 2004, Biochemistry.

Rapid Anionic Micelle-mediated α-Synuclein Fibrillization in Vitro*

Jeff Kuret, C. Chirita, J. Kuret, 2003, Journal of Biological Chemistry.

A liquid chromatography tandem mass spectroscopy approach for quantification of protein methylation stoichiometry.

J. Kuret, A. Alonso, Jean-Christophe Cocuron, 2018, Analytical biochemistry.

Detection and Reduction of Neurofibrillary Lesions

J. Kuret, 2007 .

Detection and quantification of tau aggregation using a membrane filter assay.

J. Kuret, E. Chang, 2008, Analytical biochemistry.

Potent inhibition of tau fibrillization with a multivalent ligand.

J. Kuret, J. R. Jensen, M. Darby, 2007, Biochemical and biophysical research communications.

Anionic Micelles and Vesicles Induce Tau Fibrillization in Vitro*

C. Chirita, J. Kuret, M. Necula, 2003, Journal of Biological Chemistry.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Ligand-dependent tau filament formation: implications for Alzheimer's disease progression.

J. Kuret, L. Binder, V. Ahuja, 1999, Biochemistry.

Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652

Lee, Duchen, Izzo, 2016 .

Ligand electronic properties modulate tau filament binding site density.

J. Kuret, K. Cisek, J. R. Jensen, 2012, Biophysical chemistry.

Rapid anionic micelle-mediated alpha-synuclein fibrillization in vitro.

Jeff Kuret, C. Chirita, J. Kuret, 2003, The Journal of biological chemistry.

Detection and Quantification Methods for Fibrillar Products of In Vitro Tau Aggregation Assays.

J. Kuret, N. Nanavaty, Lauren Lin, 2017, Methods in molecular biology.

Analyzing Tau Aggregation with Electron Microscopy.

J. Kuret, Carol J. Huseby, 2016, Methods in molecular biology.

Disaggregation of tau as a therapeutic approach to tauopathies.

J. Kuret, K. Duff, E. Congdon, 2010, Current Alzheimer research.

DJ-1 Molecular Chaperone Activity Depresses Tau Aggregation Propensity through Interaction with Monomers.

J. Kuret, F. Giorgini, V. Wysocki, 2023, Biochemistry.

Nitrotyrosine formation with endotoxin-induced kidney injury detected by immunohistochemistry.

F. Murad, J. Kuret, L. Binder, 1999, American journal of physiology. Renal physiology.

Oxidative regulation of fatty acid-induced tau polymerization.

J. Kuret, R. Berry, L. Binder, 2000, Biochemistry.

Selectivity requirements for diagnostic imaging of neurofibrillary lesions in Alzheimer's disease: A simulation study

Sohee Kim, Kelsey N. Schafer, Anastasios Matzavinos, 2012, NeuroImage.

Ligand electronic properties modulate tau filament binding site density.

J. Kuret, K. Cisek, J. R. Jensen, 2012, Biophysical Chemistry.

Structural Determinants of Tau Aggregation Inhibitor Potency*

J. Kuret, K. Cisek, K. Schafer, 2013, The Journal of Biological Chemistry.

Dysbindin structural homologue CK1BP is an isoform-selective binding partner of human casein kinase-1.

J. Kuret, Haishan Yin, Guibin Li, 2006, Biochemistry.

Isolation and properties of YCK2, a Saccharomyces cerevisiae homolog of casein kinase-1.

B. Chait, J. Kuret, U. Mirza, 1993, Archives of biochemistry and biophysics.

Pseudophosphorylation of tau protein directly modulates its aggregation kinetics.

J. Kuret, K. Schafer, Sohee Kim, 2011, Biochimica et biophysica acta.