P. Youngman

发表

The transcriptional profile of early to middle sporulation in Bacillus subtilis.

R. Losick, P. Fawcett, P. Eichenberger, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Construction of a cloning site near one end of Tn917 into which foreign DNA may be inserted without affecting transposition in Bacillus subtilis or expression of the transposon-borne erm gene.

P Youngman, R. Losick, P. Youngman, 1984, Plasmid.

Physical and functional characterization of the Bacillus subtilis spoIIM gene

P. Youngman, M. Bayer, K. Smith, 1993, Journal of bacteriology.

Genomic Islands in the Pathogenic Filamentous Fungus Aspergillus fumigatus

Jaideep P. Sundaram, Samuel V. Angiuoli, Joana C. Silva, 2008, PLoS genetics.

A New Mating Compatibility Locus in PHYSARUM POLYCEPHALUM.

P. Youngman, G. Struhl, B. Hosler, 1979, Genetics.

Phage Display of a Biologically Active Bacillus thuringiensis Toxin

P. Youngman, M. Adang, S. F. Garczynski, 1998, Applied and Environmental Microbiology.

Construction and properties of Tn917-lac, a transposon derivative that mediates transcriptional gene fusions in Bacillus subtilis.

P. Youngman, J. Perkins, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Random mutagenesis by recombinational capture of PCR products in Bacillus subtilis and Acinetobacter calcoaceticus.

P. Youngman, A. Melnikov, 1999, Nucleic acids research.

Expression of Listeriolysin O and ActA by Intracellular and Extracellular Listeria monocytogenes

P. Youngman, D. Portnoy, B. Levitt, 1999, Infection and Immunity.

Carbon‐source regulation of virulence gene expression in Listeria monocytogenes

P. Youngman, M. Moors, Andrea A. Milenbachs, 1997, Molecular microbiology.

Discovery of FabH/FabF Inhibitors from Natural Products

Jun Wang, John F. Barrett, Lynn L. Silver, 2006, Antimicrobial Agents and Chemotherapy.

Two Multiallelic Mating Compatibility Loci Separately Regulate Zygote Formation and Zygote Differentiation in the Myxomycete PHYSARUM POLYCEPHALUM.

R. Anderson, P. Youngman, C. E. Holt, 1981, Genetics.

New Ways to Study Developmental Genes in Spore-Forming Bacteria

R. Losick, P. Youngman, M. Igo, 1985, Science.

Insertional mutagenesis of Listeria monocytogenes with a novel Tn917 derivative that allows direct cloning of DNA flanking transposon insertions

P. Youngman, A. Camilli, A. Portnoy, 1990, Journal of bacteriology.

New genetic techniques for group B streptococci: high-efficiency transformation, maintenance of temperature-sensitive pWV01 plasmids, and mutagenesis with Tn917

P. Youngman, C. Rubens, P. Framson, 1997, Applied and environmental microbiology.

Insertional mutagenesis and recovery of interrupted genes of Streptococcus mutans by using transposon Tn917: preliminary characterization of mutants displaying acid sensitivity and nutritional requirements

P. Youngman, J. Hillman, P. Crowley, 1996, Journal of bacteriology.

xylE functions as an efficient reporter gene in Streptomyces spp.: use for the study of galP1, a catabolite-controlled promoter

P. Youngman, J. Westpheling, M. Brawner, 1989, Journal of bacteriology.

A novel method for the rapid cloning in Escherichia coli of Bacillus subtilis chromosomal DNA adjacent to Tn917 insertions

R. Losick, P. Youngman, J. Perkins, 2004, Molecular and General Genetics MGG.

Deregulation of Listeria monocytogenes virulence gene expression by two distinct and semi-independent pathways.

P. Youngman, N. Freitag, Kimberly J Mueller, 2004, Microbiology.

Bacillus subtilis expressing a haemolysin gene from Listeria monocytogenes can grow in mammalian cells

P. Youngman, D. Portnoy, P. Connelly, 1990, Nature.

Identification of compounds that inhibit late steps of peptidoglycan synthesis in bacteria.

P. Youngman, M. Hickey, D. Rothstein, 2002, The Journal of antibiotics.

Evidence that the spoIIM gene of Bacillus subtilis is transcribed by RNA polymerase associated with sigma E

P. Youngman, K. Smith, 1993, Journal of bacteriology.

A Homolog of CcpA Mediates Catabolite Control in Listeria monocytogenes but Not Carbon Source Regulation of Virulence Genes

P. Youngman, J. Behari, 1998 .

Identification of the promoter for a spore coat protein gene in Bacillus subtilis and studies on the regulation of its induction at a late stage of sporulation.

R. Losick, P. Youngman, L. Kroos, 1988, Journal of molecular biology.

A new cloning system for Bacillus subtilis comprising elements of phage, plasmid and transposon vectors.

P. Youngman, H. Poth, 1988, Gene.

GENETIC AND BIOCHEMICAL EVIDENCE THAT THE PHOSPHORYLATION STATE OF Spo0A CONTROLS THE INITIATION OF SPORULATION

P. Youngman, E. G. Ninfa, G. Olmedo, 1990 .

A new mutation in spo0A with intragenic suppressors in the effector domain.

P. Youngman, A. Wilkinson, R. Lewis, 2000, FEMS microbiology letters.

PAP inhibitor with in vivo efficacy identified by Candida albicans genetic profiling of natural products.

Yang Li, Li Zhang, Guy Harris, 2008, Chemistry & biology.

Antimicrobials: new solutions badly needed.

P. Youngman, S. Projan, 2002, Current opinion in microbiology.

Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus.

P. Youngman, T. Roemer, J. Becker, 2007, Chemistry & biology.

Genome-Wide Fitness Test and Mechanism-of-Action Studies of Inhibitory Compounds in Candida albicans

Terry Roemer, Troy Ketela, H. Bussey, 2007, PLoS pathogens.

Structure and function of the Bacillus SpoIIE protein and its localization to sites of sporulation septum assembly

P. Youngman, P. Guzmán, J. Westpheling, 1996, Molecular microbiology.

Regulation of bacterial differentiation

P. Youngman, C. Moran, P. Piggot, 1993 .

The Bacillus SpoIIGA protein is targeted to sites of spore septum formation in a SpoIIE‐independent manner

P. Fawcett, P. Youngman, Alexandre Melnikov, 1998, Molecular microbiology.

A Staphylococcus aureus fitness test platform for mechanism-based profiling of antibacterial compounds.

Sang Ho Lee, C. Malone, J. Phillips, 2009, Chemistry & biology.

Transposons and Their Applications

P. Youngman, 1993 .

Genetic analysis of Bacillus subtilis spo mutations generated by Tn917-mediated insertional mutagenesis.

R. Losick, P. Youngman, K. Sandman, 1987, Genetics.

Genetic transposition and insertional mutagenesis in Bacillus subtilis with Streptococcus faecalis transposon Tn917.

R. Losick, P. Youngman, J. Perkins, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Kinetics of mating in Physarum polycephalum.

P. Youngman, T. Shinnick, D. Pallotta, 1979, Mycologia.

Use of a new integrational vector to investigate compartment-specific expression of the Bacillus subtilis spoIIM gene.

P. Youngman, K. Smith, 1992, Biochimie.

A physical and functional analysis of Tn917, a Streptococcus transposon in the Tn3 family that functions in Bacillus.

P. Youngman, J. Perkins, 1984, Plasmid.

Streptococcus plasmid pAM alpha 1 is a composite of two separable replicons, one of which is closely related to Bacillus plasmid pBC16

P. Youngman, J. Perkins, 1983, Journal of bacteriology.

Genetics of endospore formation in Bacillus subtilis.

R. Losick, P. Youngman, P. Piggot, 1986, Annual review of genetics.

Endospore Formation in Bacillus

R. Losick, P. Youngman, 1984 .

γ-Glutamyltransferase Is a Helicobacter pylori Virulence Factor but Is Not Essential for Colonization

P. Youngman, S. Czinn, S. Krakowka, 2001, Infection and Immunity.

Novel mutations that alter the regulation of sporulation in Bacillus subtilis. Evidence that phosphorylation of regulatory protein SpoOA controls the initiation of sporulation.

P. Youngman, J. Stock, E. G. Ninfa, 1990, Journal of molecular biology.

Identification of a Bacillus subtilis spo0H allele that is necessary for suppression of the sporulation-defective phenotype of a spo0A mutation

P. Youngman, M. Bramucci, N. Ambulos, 1995, Journal of bacteriology.

Genetic evidence that RNA polymerase associated with sigma A factor uses a sporulation-specific promoter in Bacillus subtilis.

P. Youngman, C. Moran, T. J. Kenney, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Genetic Manipulations with Phage SPß1

P. Youngman, S. Zahler, P. Fink, 1982 .

Genome‐wide analysis of the general stress response in Bacillus subtilis

P Youngman, P. Fawcett, P. Youngman, 2001, Molecular microbiology.

NEW GENETIC METHODS, MOLECULAR CLONING STRATEGIES AND GENE FUSION TECHNIQUES FOR BACILLUS SUBTILIS WHICH TAKE ADVANTAGE OF Tn917 INSERTIONAL MUTAGENESIS1

P. Youngman, J. Perkins, K. Sandman, 1984 .

Pathways of developmentally regulated gene expression in the spore-forming bacterium Bacillus subtilis

R. Losick, P. Youngman, J. Errington, 1988 .

Characterization of the promoter region of the Bacillus subtilis spoIIE operon

P. Youngman, P. Guzmán, J. Westpheling, 1988, Journal of bacteriology.

Chapter 11 – Pathways of Developmentally Regulated Gene Expression in Bacillus subtilis

R. Losick, P. Youngman, J. Errington, 1989 .

The promoter for a sporulation gene in the spoIVC locus of Bacillus subtilis and its use in studies of temporal and spatial control of gene expression

R. Losick, P. Youngman, B. Kunkel, 1988, Journal of bacteriology.

Temporal and spatial control of the mother-cell regulatory gene spoIIID of Bacillus subtilis.

R. Losick, P. Youngman, L. Kroos, 1989, Genes & development.

Transcriptional activation of the Listeria monocytogenes hemolysin gene in Bacillus subtilis

P. Youngman, D. Portnoy, N. Freitag, 1992, Journal of bacteriology.

Staphylococcus aureus TargetArray: Comprehensive Differential Essential Gene Expression as a Mechanistic Tool To Profile Antibacterials

Terry Roemer, Rich Archer, Paula King, 2010, Antimicrobial Agents and Chemotherapy.

Phosphorylation of Bacillus subtilis transcription factor Spo0A stimulates transcription from the spoIIG promoter by enhancing binding to weak 0A boxes

P. Youngman, C. Moran, B. D. Green, 1994, Journal of bacteriology.

Mutational Analysis of Conserved Residues in the Putative DNA-Binding Domain of the Response Regulator Spo0A ofBacillus subtilis

P. Youngman, J. Hatt, 2000, Journal of bacteriology.

Crystallization of the regulatory and effector domains of the key sporulation response regulator Spo0A.

P. Youngman, A. Wilkinson, R. Lewis, 1999, Acta crystallographica. Section D, Biological crystallography.

SpoIIE mutants of Bacillus subtilis comprise two distinct phenotypic classes consistent with a dual functional role for the SpoIIE protein

P. Youngman, I. Barák, 1996, Journal of bacteriology.

Genomics technologies and strategies for identification of novel anti-infective agents.

P. Youngman, R. Tepper, J. Moore, 2001, Current clinical topics in infectious diseases.

Regulation of hly Expression inListeria monocytogenes by Carbon Sources and pH Occurs through Separate Mechanisms Mediated by PrfA

P. Youngman, J. Behari, 1998, Infection and Immunity.

Spo0A directly controls the switch from acid to solvent production in solvent‐forming clostridia

P. Youngman, M. Young, D. Young, 2000, Molecular microbiology.

Spo0A controls the sigma A-dependent activation of Bacillus subtilis sporulation-specific transcription unit spoIIE

P Youngman, T J Kenney, P. Youngman, 1992, Journal of bacteriology.

Jaideep Behari and Philip Youngman Mediated by PrfA Occurs through Separate Mechanisms by Carbon Sources and pH monocytogenes Listeria Expression in hly Regulation of

P. Youngman, J. Behari, 1998 .

Characterization of spo0A homologues in diverse Bacillus and Clostridium species identifies a probable DNA‐binding domain

P. Youngman, L. Ganova-Raeva, S. Wilkinson, 1994, Molecular microbiology.

Weak OA Boxes

P. Youngman, C. Moran, J. Baldus, 2022 .

Tn917-lac mutagenesis of Streptococcus mutans to identify environmentally regulated genes.

P. Youngman, D. Cvitkovitch, L. Brady, 2000, FEMS microbiology letters.

Spo0A Mutants of Bacillus subtilis with Sigma Factor-Specific Defects in Transcription Activation

P. Youngman, J. Hatt, 1998, Journal of bacteriology.

An extracellular inducer of asexual plasmodium formation in Physarum polycephalum.

P. Adler, P. Youngman, T. Shinnick, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Complementation of npf mutations in diploid amoebae of Physarum polycephalum: the basis for a general method of complementation analysis at the amoebal stage.

R. Anderson, P. Youngman, 1985, Genetical research.

A gene,imz, affecting the pH sensitivity of zygote formation inPhysarum polycephalum

P. Youngman, T. Shinnick, D. Pallotta, 2007, Current Microbiology.

A homolog of CcpA mediates catabolite control in Listeria monocytogenes but not carbon source regulation of virulence genes.

P. Youngman, J. Behari, 1998, Journal of bacteriology.

NOVEL INTEGRATIONAL VECTORS FOR BACILLUS SUBTILIS BASED ON COLIPHAGE Ml3 AND THEIR USE FOR THE ANALYSIS OF REGULATED PROMOTERS

P. Youngman, P. Guzmán, 1988 .