E. Huttlin

发表

Architecture of the human interactome defines protein communities and disease networks

Devin K. Schweppe, Edward L. Huttlin, S. Gygi, 2017, Nature.

Quantitative Temporal Viromics: An Approach to Investigate Host-Pathogen Interaction

Edward L. Huttlin, David P. Nusinow, S. Gygi, 2014, Cell.

MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes

Edward L. Huttlin, David P. Nusinow, S. Gygi, 2014, Analytical chemistry.

A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

Edward L. Huttlin, Joshua E. Elias, S. Gygi, 2010, Cell.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, S. Gygi, Fana Gebreab, 2015, Cell.

An ultra-tolerant database search reveals that a myriad of modified peptides contributes to unassigned spectra in shotgun proteomics

Edward L. Huttlin, David P. Nusinow, S. Gygi, 2015, Nature Biotechnology.

Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses.

Edward L. Huttlin, Robert A. Grothe, S. Gygi, 2012, Analytical chemistry.

Evaluation of HCD- and CID-type Fragmentation Within Their Respective Detection Platforms For Murine Phosphoproteomics*

Edward L. Huttlin, S. Gygi, M. Sowa, 2011, Molecular & Cellular Proteomics.

A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides

Edward L. Huttlin, David P. Nusinow, S. Gygi, 2015, Nature Biotechnology.

A large-scale method to measure absolute protein phosphorylation stoichiometries

Edward L. Huttlin, S. Gygi, Noah Dephoure, 2011, Nature Methods.

Systematic and quantitative assessment of the ubiquitin-modified proteome.

Edward L. Huttlin, S. Gygi, M. Sowa, 2011, Molecular cell.

Mass spectrometry based method to increase throughput for kinome analyses using ATP probes.

S. Gygi, P. Sorger, M. Niepel, 2013, Analytical chemistry.

Whole-genome expression profiling of the marine diatom Thalassiosira pseudonana identifies genes involved in silicon bioprocesses

Thomas Mock, Edward L Huttlin, Vaughn Iverson, 2008, Proceedings of the National Academy of Sciences.

Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions

Edward L. Huttlin, E. Huttlin, M. Weekes, 2019, eLife.

A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging

Devin K. Schweppe, Edward L. Huttlin, Edward T Chouchani, 2020, Cell.

Defining the consequences of genetic variation on a proteome-wide scale

Steven P. Gygi, Daniel M. Gatti, Gary A. Churchill, 2016, Nature.

TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples

Devin K. Schweppe, Edward L. Huttlin, S. Gygi, 2020, Nature Methods.

Democratization and integration of genomic profiling tools.

E. Huttlin, M. Sussman, Dana J. Wohlbach, 2009, Methods in molecular biology.

Implications of 15N‐metabolic labeling for automated peptide identification in Arabidopsis thaliana

Edward L Huttlin, Edward L. Huttlin, Adrian D Hegeman, 2007, Proteomics.

Discovery and validation of colonic tumor-associated proteins via metabolic labeling and stable isotopic dilution

Edward L. Huttlin, M. Newton, E. Huttlin, 2009, Proceedings of the National Academy of Sciences.

Candidate serum biomarkers for early intestinal cancer using 15N metabolic labeling and quantitative proteomics in the ApcMin/+ mouse.

Edward L. Huttlin, E. Huttlin, M. Sussman, 2013, Journal of proteome research.

Architecture of the outbred brown fat proteome defines regulators of metabolic physiology

Edward L. Huttlin, Alexander S. Banks, Edward T Chouchani, 2022, Cell.

A multi-purpose, regenerable, proteome-scale, human phosphoserine resource for phosphoproteomics

S. Gygi, E. Huttlin, J. Paulo, 2022, Nature Methods.

Proteome-wide mapping of short-lived proteins in human cells.

Edward L. Huttlin, S. Gygi, E. Huttlin, 2021, Molecular cell.

QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology

Edward L. Huttlin, S. Gygi, J. Harper, 2015, eLife.

Mapping cell structure across scales by fusing protein images and interactions

Jianzhu Ma, Trey Ideker, Wei Ouyang, 2020, bioRxiv.

A proteome-wide atlas of drug mechanism of action

Devin K. Schweppe, Edward L. Huttlin, S. Gygi, 2023, Nature Biotechnology.

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome

Ramin Rad, Steven P. Gygi, Fana Gebreab, 2020, Cell.

Selection of Heating Temperatures Improves the Sensitivity of Proteome Integral Solubility Alteration (PISA) Assay.

Edward L. Huttlin, S. Gygi, E. Huttlin, 2020, Journal of proteome research.

Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics

Ramin Rad, Steven P. Gygi, Brian K. Erickson, 2019, bioRxiv.

Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux

Edward L. Huttlin, J. Harper, E. Huttlin, 2017, Molecular and Cellular Biology.

Chapter 20 Metabolic Labeling Approaches for the Relative Quantification of Proteins

Edward L. Huttlin, E. Huttlin, M. Sussman, 2008 .

Comparison of Full Versus Partial Metabolic Labeling for Quantitative Proteomics Analysis in Arabidopsis thaliana*S

Michael R. Sussman, Edward L. Huttlin, Adrian D. Hegeman, 2007, Molecular & Cellular Proteomics.

Systematic VCP-UBXD Adaptor Network Proteomics Identifies a Role for UBXN10 in Regulating Ciliogenesis

Edward L. Huttlin, W. Goessling, J. Harper, 2016 .

Gab2 Phosphorylation by RSK Inhibits Shp2 Recruitment and Cell Motility

Edward L. Huttlin, S. Gygi, Philippe P Roux, 2013, Molecular and Cellular Biology.

Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression

Devin K. Schweppe, Edward L. Huttlin, S. Gygi, 2023, Nature Communications.

Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast

Edward L. Huttlin, David P. Nusinow, S. Gygi, 2019, Cell reports.

A Transcriptome-Based Characterization of Habituation in Plant Tissue Culture1[W]

Edward L. Huttlin, E. Huttlin, M. Sussman, 2006, Plant Physiology.

Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5′TOP mRNA translation

Edward L Huttlin, Steven P Gygi, Edward L. Huttlin, 2014, Genes & development.

TIMMDC1/C3orf1 Functions as a Membrane-Embedded Mitochondrial Complex I Assembly Factor through Association with the MCIA Complex

Edward L. Huttlin, S. Gygi, J. Harper, 2013, Molecular and Cellular Biology.

Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization

Steven P. Gygi, Edward L. Huttlin, J. Wade Harper, 2013, Nature.

Global analysis of protein expression and phosphorylation of three stages of Plasmodium falciparum intraerythrocytic development.

Edward L Huttlin, Steven P Gygi, Edward L. Huttlin, 2013, Journal of proteome research.

Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

Edward L. Huttlin, S. Elledge, S. Gygi, 2015, Molecular cell.

Human Polo-like Kinase Inhibitors as Antiplasmodials.

Edward L. Huttlin, E. Winzeler, S. Gygi, 2023, ACS infectious diseases.

Neutral Loss Is a Very Common Occurrence in Phosphotyrosine-Containing Peptides Labeled with Isobaric Tags.

Edward L. Huttlin, Alison R Erickson, S. Gygi, 2017, Journal of proteome research.

Correct Interpretation of Comprehensive Phosphorylation Dynamics Requires Normalization by Protein Expression Changes*

Edward L Huttlin, Steven P Gygi, Wilhelm Haas, 2011, Molecular & Cellular Proteomics.

TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples

Devin K. Schweppe, Edward L. Huttlin, S. Gygi, 2020, Nature Methods.

High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms

Edward L. Huttlin, E. Huttlin, M. Weekes, 2018, Cell host & microbe.

Compositional Proteomics: Effects of Spatial Constraints on Protein Quantification Utilizing Isobaric Tags

Michael P Weekes, Edward L Huttlin, Steven P Gygi, 2017, Journal of proteome research.

BioPlex Display: An Interactive Suite for Large-Scale AP-MS Protein-Protein Interaction Data.

Devin K Schweppe, Edward L Huttlin, J Wade Harper, 2018, Journal of proteome research.

Stable isotope assisted assignment of elemental compositions for metabolomics.

Edward L Huttlin, John L Markley, Eldon L Ulrich, 2007, Analytical chemistry.

Altered glutamine metabolism of cultured fibroblasts predicts severity of cardiac dysfunction in the dilated cardiomyopathy with ataxia syndrome (DCMA), a mitochondrial cardiomyopathy

Edward L. Huttlin, E. Huttlin, Aneal Khan, 2020 .

Characterization of Plasmodium falciparum Atypical Kinase PfPK7- Dependent Phosphoproteome.

Edward L Huttlin, Steven P Gygi, Ratna Chakrabarti, 2018, Journal of proteome research.

BioPlexR and BioPlexPy: integrated data products for the analysis of human protein interactions

R. Gentleman, E. Huttlin, Joshua Pan, 2023, Bioinformatics.

Phosphorylation of the Eukaryotic Translation Initiation Factor 4E-Transporter (4E-T) by c-Jun N-Terminal Kinase Promotes Stress-Dependent P-Body Assembly

Edward L. Huttlin, S. Gygi, Philippe P Roux, 2012, Molecular and Cellular Biology.

Biallelic Mutations in DNAJC12 Cause Hyperphenylalaninemia, Dystonia, and Intellectual Disability.

Edward L. Huttlin, J. Mullikin, T. Meitinger, 2017, American journal of human genetics.

Proteomic analysis of circulating immune cells identifies novel cellular phenotypes associated with COVID-19 severity

Edward L. Huttlin, Kenneth G. C. Smith, B. Göttgens, 2022, medRxiv.

An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation

Edward L. Huttlin, E. Huttlin, M. Weekes, 2023, Molecular cell.

A multi-scale map of cell structure fusing protein images and interactions

Edward L. Huttlin, Gene W. Yeo, Casper F. Winsnes, 2021, Nature.

Reply to "Phosphorylation sites of higher stoichiometry are more conserved"

S. Gygi, M. Sowa, E. Huttlin, 2012, Nature Methods.

Matching isotopic distributions from metabolically labeled samples

David Page, Sean McIlwain, Edward L. Huttlin, 2008, ISMB.

Using dynamic programming to create isotopic distribution maps from mass spectra

David Page, Sean McIlwain, Edward L. Huttlin, 2007, ISMB/ECCB.

Prediction of error associated with false-positive rate determination for peptide identification in large-scale proteomics experiments using a combined reverse and forward peptide sequence database strategy.

Edward L Huttlin, Edward L. Huttlin, Adrian D Hegeman, 2007, Journal of proteome research.