J. Gaddy

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Role of Connexin 43 in Helicobacter pylori VacA-Induced Cell Death

Jinsong Sheng, D. Rubin, Jana N Radin, 2013, Infection and Immunity.

Identification of Two Variants of Acinetobacter baumannii Strain ATCC 17978 with Distinct Genotypes and Phenotypes

Eric P. Skaar, S. Menon, J. Gaddy, 2021, Infection and immunity.

Insights into reference point indentation involving human cortical bone: sensitivity to tissue anisotropy and mechanical behavior.

J. Nyman, M. Does, J. Gaddy, 2014, Journal of the mechanical behavior of biomedical materials.

Peptidomimetic Small Molecules Disrupt Type IV Secretion System Activity in Diverse Bacterial Pathogens

J. Gaddy, T. Cover, M. Hadjifrangiskou, 2016, mBio.

Helicobacter pylori: Genomic Insight into the Host-Pathogen Interaction

J. Gaddy, K. Haley, 2015, International journal of genomics.

Genes Required for Assembly of Pili Associated with the Helicobacter pylori cag Type IV Secretion System

J. Gaddy, T. Cover, E. Hennig, 2014, Infection and Immunity.

The Human Antimicrobial Protein Calgranulin C Participates in Control of Helicobacter pylori Growth and Regulation of Virulence

Eric P. Skaar, J. Gaddy, W. Chazin, 2015, Infection and Immunity.

Metal homeostasis in pathogenic Epsilonproteobacteria: mechanisms of acquisition, efflux, and regulation.

J. Gaddy, Jacky Lu, Jeremiah G. Johnson, 2020, Metallomics : integrated biometal science.

Characterization of Key Helicobacter pylori Regulators Identifies a Role for ArsRS in Biofilm Formation

Stephanie L. Servetas, J. Gaddy, D. Merrell, 2016, Journal of bacteriology.

Metalloregulation of Helicobacter pylori physiology and pathogenesis

J. Gaddy, K. Haley, 2015, Front. Microbiol..

Impaired Autophagy, Defective T Cell Homeostasis, and a Wasting Syndrome in Mice with a T Cell–Specific Deletion of Vps34

Vrajesh V. Parekh, W. Zong, J. Gaddy, 2013, The Journal of Immunology.

Analysis of Surface-Exposed Outer Membrane Proteins in Helicobacter pylori

J. Gaddy, T. Cover, W. McDonald, 2014, Journal of bacteriology.

Clinical investigation of biofilm in non-healing wounds by high resolution microscopy techniques.

J. Gaddy, J. Hurlow, E. Blanz, 2016, Journal of wound care.

Synthetic Ellagic Acid Glycosides Inhibit Early-Stage Adhesion of Streptococcus agalactiae Biofilms as Observed by Scanning Electron Microscopy.

J. Gaddy, Steven D. Townsend, Schuyler A. Chambers, 2020, Chemistry.

Human Milk Oligosaccharides (HMOs) Sensitize Group B Streptococcus to Clindamycin, Erythromycin, Gentamicin, and Minocycline on a Strain Specific Basis.

J. Gaddy, Steven D. Townsend, K. Craft, 2018, ACS chemical biology.

Antimicrobial and Antibiofilm Activity of Human Milk Oligosaccharides against Streptococcus agalactiae, Staphylococcus aureus, and Acinetobacter baumannii.

D. Aronoff, J. Gaddy, J. Weitkamp, 2017, ACS infectious diseases.

Human Milk Oligosaccharides Exhibit Antimicrobial and Antibiofilm Properties against Group B Streptococcus.

D. Aronoff, J. Gaddy, J. Weitkamp, 2017, ACS infectious diseases.

Decidual stromal cell‐derived PGE2 regulates macrophage responses to microbial threat

K. Osteen, D. Aronoff, J. Gaddy, 2018, American journal of reproductive immunology.

The PAS Domain-Containing Protein HeuR Regulates Heme Uptake in Campylobacter jejuni

J. Gaddy, V. DiRita, Jeremiah G. Johnson, 2016, mBio.

High Dietary Salt Intake Exacerbates Helicobacter pylori-Induced Gastric Carcinogenesis

M. Washington, Jana N Radin, J. Gaddy, 2013, Infection and Immunity.

Iron deficiency accelerates Helicobacter pylori-induced carcinogenesis in rodents and humans.

D. Morgan, L. Bravo, J. Gaddy, 2013, The Journal of clinical investigation.

Helicobacter pylori Adaptation In Vivo in Response to a High-Salt Diet

S. Mallal, J. Gaddy, H. Algood, 2015, Infection and Immunity.

Investigation of the Role That NADH Peroxidase Plays in Oxidative Stress Survival in Group B Streptococcus

D. Aronoff, J. Gaddy, Rebecca A. Flaherty, 2018, Front. Microbiol..

The antimicrobial activity of zinc against group B Streptococcus is strain-dependent across diverse sequence types, capsular serotypes, and invasive versus colonizing isolates

S. Madhi, D. Aronoff, J. Gaddy, 2022, BMC microbiology.

Analysis of Susceptibility to the Antimicrobial and Anti-Biofilm Activity of Human Milk Lactoferrin in Clinical Strains of Streptococcus agalactiae With Diverse Capsular and Sequence Types

J. Gaddy, Jacky Lu, S. Manning, 2021, Frontiers in Cellular and Infection Microbiology.

The Influence of Obesity and Associated Fatty Acids on Placental Inflammation.

D. Aronoff, J. Gaddy, A. Eastman, 2021, Clinical therapeutics.

Group B Streptococcus Induces Neutrophil Recruitment to Gestational Tissues and Elaboration of Extracellular Traps and Nutritional Immunity

D. Aronoff, J. Gaddy, K. Boyd, 2017, Front. Cell. Infect. Microbiol..

This information is current as Specific Deletion of Vps 34 − Mice with a T Cell Homeostasis , and a Wasting Syndrome in Impaired Autophagy , Defective T Cell

Vrajesh V. Parekh, W. Zong, J. Gaddy, 2013 .

Distinct Group B Streptococcus Sequence and Capsule Types Differentially Impact Macrophage Stress and Inflammatory Signaling Responses

D. Aronoff, J. Gaddy, M. Petroff, 2021, Infection and Immunity.

Genetically distinct Group B Streptococcus strains induce varying macrophage cytokine responses

D. Aronoff, J. Gaddy, M. Petroff, 2019, PloS one.

Proceedings of the 16th Annual UT-KBRIN Bioinformatics Summit 2016: proceedings

Sammed N. Mandape, J. Stephens, T. Kalbfleisch, 2017, BMC Proceedings.

Flagellar Localization of a Helicobacter pylori Autotransporter Protein

Jana N Radin, Christian González-Rivera, J. Gaddy, 2013, mBio.

Group B Streptococcus cpsE Is Required for Serotype V Capsule Production and Aids in Biofilm Formation and Ascending Infection of the Reproductive Tract during Pregnancy.

D. Aronoff, J. Gaddy, Kristen N. Noble, 2021, ACS infectious diseases.

A Solution to Antifolate Resistance in Group B Streptococcus: Untargeted Metabolomics Identifies Human Milk Oligosaccharide-Induced Perturbations That Result in Potentiation of Trimethoprim

D. Aronoff, J. Gaddy, J. McLean, 2020, mBio.

Vitamin D and Streptococci: The Interface of Nutrition, Host Immune Response, and Antimicrobial Activity in Response to Infection.

K. Osteen, D. Aronoff, J. Gaddy, 2020, ACS infectious diseases.

Production and Composition of Group B Streptococcal Membrane Vesicles Vary Across Diverse Lineages

D. Aronoff, J. Gaddy, M. Petroff, 2021, Frontiers in Microbiology.

Modulation of Death and Inflammatory Signaling in Decidual Stromal Cells following Exposure to Group B Streptococcus

D. Aronoff, J. Gaddy, M. Petroff, 2019, Infection and Immunity.

Analysis of virulence phenotypes and antibiotic resistance in clinical strains of Acinetobacter baumannii isolated in Nashville, Tennessee

J. Gaddy, Jacky Lu, S. Manning, 2021, BMC microbiology.

The Host Protein Calprotectin Modulates the Helicobacter pylori cag Type IV Secretion System via Zinc Sequestration

Eric P. Skaar, J. Gaddy, T. Cover, 2014, PLoS pathogens.

Group B streptococcal membrane vesicles induce proinflammatory cytokine production and are sensed in an NLRP3 inflammasome-dependent mechanism in human macrophages

D. Aronoff, J. Gaddy, M. Petroff, 2022, bioRxiv.

Highly differentiated human airway epithelial cells: a model to study host cell–parasite interactions in pertussis

F. Mooi, J. Gaddy, M. Decker, 2016, Infectious diseases.

Production and composition of group B streptococcal membrane vesicles varies across diverse lineages

D. Aronoff, J. Gaddy, M. Petroff, 2021, bioRxiv.

Lactoferrin: a critical mediator of both host immune response and antimicrobial activity in response to streptococcal infections.

K. Osteen, D. Aronoff, J. Gaddy, 2020, ACS infectious diseases.

Induction of neutrophil extracellular traps by Campylobacter jejuni

J. Gaddy, S. Callahan, Jeremiah G. Johnson, 2020, Cellular microbiology.

Role of Acinetobactin-Mediated Iron Acquisition Functions in the Interaction of Acinetobacter baumannii Strain ATCC 19606T with Human Lung Epithelial Cells, Galleria mellonella Caterpillars, and Mice

J. Gaddy, R. López-Rojas, M. McConnell, 2012, Infection and Immunity.

High resolution electron microscopy of the Helicobacter pylori Cag type IV secretion system pili produced in varying conditions of iron availability.

J. Gaddy, K. Haley, E. Blanz, 2014, Journal of visualized experiments : JoVE.

ArsRS-Dependent Regulation of homB Contributes to Helicobacter pylori Biofilm Formation

Stephanie L. Servetas, J. Gaddy, D. Merrell, 2018, Front. Microbiol..

Iron acquisition functions expressed by the human pathogen Acinetobacter baumannii

J. Gaddy, L. Actis, P. L. Connerly, 2009, BioMetals.

Enteroinvasive Escherichia coli O96:H19 is an Emergent Biofilm-Forming Pathogen

J. Gaddy, J. Iqbal, K. Haley, 2022, Journal of bacteriology.

Staphylococcus aureus Infection of Human Gestational Membranes Induces Bacterial Biofilm Formation and Host Production of Cytokines

D. Aronoff, J. Gaddy, Lauren M. Tetz, 2016, The Journal of infectious diseases.

Variation in Macrophage Phagocytosis of Streptococcus agalactiae Does Not Reflect Bacterial Capsular Serotype, Multilocus Sequence Type, or Association with Invasive Infection

D. Aronoff, J. Gaddy, S. Manning, 2018, Pathogens & immunity.

Analysis of Antimicrobial and Antibiofilm Activity of Human Milk Lactoferrin Compared to Bovine Lactoferrin against Multidrug Resistant and Susceptible Acinetobacter baumannii Clinical Isolates.

J. Gaddy, Jacky Lu, S. Manning, 2021, ACS infectious diseases.

Ameliorating adverse perinatal outcomes with Lactoferrin: An intriguing chemotherapeutic intervention.

J. Gaddy, Jacky Lu, Steven D. Townsend, 2022, Bioorganic & medicinal chemistry.

Recent advances on human milk oligosaccharide antimicrobial activity.

J. Gaddy, Steven D. Townsend, Sabrina K. Spicer, 2022, Current opinion in chemical biology.

Epidemiological Trends of Racial Differences in Early- and Late-Onset Group B Streptococcus Disease in Tennessee.

W. Schaffner, D. Aronoff, J. Gaddy, 2020, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The Host Antimicrobial Protein Calgranulin C Participates in the Control of Campylobacter jejuni Growth via Zinc Sequestration

Joseph W. Jackson, J. Gaddy, Jeremiah G. Johnson, 2018, Infection and Immunity.

The Innate Immune Glycoprotein Lactoferrin Represses the Helicobacter pylori cag Type IV Secretion System

J. Gaddy, M. Piazuelo, Jacky Lu, 2021, Chembiochem : a European journal of chemical biology.

Streptococcus agalactiae cadD alleviates metal stress and promotes intracellular survival in macrophages and ascending infection during pregnancy

D. Aronoff, J. Gaddy, Kristen N. Noble, 2022, Nature Communications.

Synthetic Phosphoethanolamine Cellobiose Promotes Escherichia coli Biofilm Formation and Congo Red Binding

J. Gaddy, Steven D. Townsend, Rebecca E. Moore, 2021, Chembiochem : a European journal of chemical biology.

Streptococcus agalactiae npx Is Required for Survival in Human Placental Macrophages and Full Virulence in a Model of Ascending Vaginal Infection during Pregnancy

D. Aronoff, J. Gaddy, Kristen N. Noble, 2022, bioRxiv.

Battle for the histones: a secreted bacterial sirtuin from Campylobacter jejuni activates neutrophils and induces inflammation during infection

J. Gaddy, S. Callahan, Jeremiah G. Johnson, 2022, bioRxiv.

Leveraging Stereoelectronic Effects in Biofilm Eradication: Synthetic β-Amino Human Milk Oligosaccharides Impede Microbial Adhesion as Observed by Scanning Electron Microscopy.

J. Gaddy, Lianyan L Xu, Steven D. Townsend, 2020, The Journal of organic chemistry.

Enterococci enhance Clostridioides difficile pathogenesis

Matthew L. Jenior, Brendan J. Kelly, Eric P. Skaar, 2022, Nature.

Anti-biofilm activity of human milk oligosaccharides against multi-drug resistant and susceptible isolates of Acinetobacter baumannii

J. Gaddy, Jacky Lu, S. Manning, 2022 .

The Acinetobacter baumannii 19606 OmpA Protein Plays a Role in Biofilm Formation on Abiotic Surfaces and in the Interaction of This Pathogen with Eukaryotic Cells

J. Gaddy, L. Actis, A. Tomaras, 2009, Infection and Immunity.

Current concepts in maternal–fetal immunology: Recognition and response to microbial pathogens by decidual stromal cells

D. Aronoff, J. Gaddy, Ryan S. Doster, 2017, American journal of reproductive immunology.

Characterization of a two-component regulatory system from Acinetobacter baumannii that controls biofilm formation and cellular morphology.

J. Gaddy, L. Actis, A. Tomaras, 2008, Microbiology.

The Opportunistic Human Pathogen Acinetobacter baumannii Senses and Responds to Light

J. Gaddy, A. Viale, L. Actis, 2010, Journal of bacteriology.

Chapter 3 CsuA / BABCDE-dependent pili are not involved in the adherence of Acinetobacter baumannii ATCC 19606 T to human airway epithelial cells and their inflammatory response

A. Koster, J. Gaddy, L. Dijkshoorn, 2012 .

Acinetobacter baumannii Virulence Attributes: The Roles of Outer Membrane Protein A, Acinetobactin-mediated Iron Acquisition Functions, and Blue Light Sensing Protein A

J. Gaddy, 2010 .

CsuA/BABCDE-dependent pili are not involved in the adherence of Acinetobacter baumannii ATCC19606(T) to human airway epithelial cells and their inflammatory response.

A. Koster, J. Gaddy, L. Dijkshoorn, 2009, Research in microbiology.

Streptococcus agalactiae cadD Is Critical for Pathogenesis in the Invertebrate Galleria mellonella Model.

J. Gaddy, Jacky Lu, S. Manning, 2022, ACS infectious diseases.

Deciphering the iron response in Acinetobacter baumannii: A proteomics approach.

J. Gaddy, L. Actis, D. Zimbler, 2011, Journal of proteomics.

Macrophage Extracellular Traps: A Scoping Review

D. Aronoff, J. Gaddy, L. Rogers, 2017, Journal of Innate Immunity.

Molecular analysis of idiopathic subglottic stenosis for Mycobacterium species

J. Netterville, C. Stratton, J. Gaddy, 2016, The Laryngoscope.

Idiopathic subglottic stenosis is associated with activation of the inflammatory IL‐17A/IL‐23 axis

J. Netterville, C. Stratton, J. Gaddy, 2016, The Laryngoscope.

Protein kinase D mediates inflammatory responses of human placental macrophages to Group B Streptococcus

D. Aronoff, J. Gaddy, Rebecca A. Flaherty, 2019, American journal of reproductive immunology.

Antibiofilm Activity of Human Milk Oligosaccharides against Multidrug Resistant and Susceptible Isolates of Acinetobacter baumannii.

J. Gaddy, Jacky Lu, S. Manning, 2021, ACS infectious diseases.

S100A12 in Digestive Diseases and Health: A Scoping Review

J. Gaddy, Jacky Lu, Jeremiah G. Johnson, 2020, Gastroenterology research and practice.

The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction

Catherine A. Wakeman, Eric P. Skaar, R. Caprioli, 2016, Nature Communications.

Effect of Ethanol on Differential Protein Production and Expression of Potential Virulence Functions in the Opportunistic Pathogen Acinetobacter baumannii

J. Gaddy, L. Actis, Brock A Arivett, 2012, PloS one.

The impact of Lactobacillus on group B streptococcal interactions with cells of the extraplacental membranes.

D. Aronoff, J. Gaddy, S. Manning, 2020, Microbial pathogenesis.

Functional Plasticity in the Type IV Secretion System of Helicobacter pylori

J. Gaddy, T. Cover, R. Peek, 2013, PLoS pathogens.

Regulation of Acinetobacter baumannii biofilm formation.

J. Gaddy, L. Actis, 2009, Future microbiology.

Raman microspectroscopy differentiates perinatal pathogens on ex vivo infected human fetal membrane tissues

D. Aronoff, J. Gaddy, A. Mahadevan-Jansen, 2019, Journal of biophotonics.

CagY-Dependent Regulation of Type IV Secretion in Helicobacter pylori Is Associated with Alterations in Integrin Binding

J. Gaddy, S. Simon, J. Solnick, 2018, mBio.

Helicobacter pylori Resists the Antimicrobial Activity of Calprotectin via Lipid A Modification and Associated Biofilm Formation

Eric P. Skaar, T. Cullen, J. Gaddy, 2015, mBio.

Association between genotypic diversity and biofilm production in group B Streptococcus

H. Davies, J. Gaddy, R. Zadoks, 2016, BMC Microbiology.

Antibacterial and Anti‐biofilm Activity of the Human Breast Milk Glycoprotein Lactoferrin against Group B Streptococcus

D. Aronoff, J. Gaddy, A. Eastman, 2021, Chembiochem : a European journal of chemical biology.

Helicobacter pylori Exploits a Unique Repertoire of Type IV Secretion System Components for Pilus Assembly at the Bacteria-Host Cell Interface

J. Gaddy, M. S. McClain, T. Cover, 2011, PLoS pathogens.

Nutrition and Helicobacter pylori: Host Diet and Nutritional Immunity Influence Bacterial Virulence and Disease Outcome

J. Gaddy, K. Haley, 2016, Gastroenterology research and practice.

Optimizing In Situ Proximity Ligation Assays for Mitochondria, ER, or MERC Markers in Skeletal Muscle Tissue and Cells

J. Gaddy, J. Shao, Lar L. Vang, 2023, bioRxiv.

Association between genotypic diversity and biofilm production in group B Streptococcus

H. Davies, J. Gaddy, R. Zadoks, 2016, BMC Microbiology.

Drug-Resistant Staphylococcus aureus Strains Reveal Distinct Biochemical Features with Raman Microspectroscopy.

Anita Mahadevan-Jansen, Eric P Skaar, Isaac J Pence, 2018, ACS infectious diseases.

Alterations in Helicobacter pylori Triggered by Contact with Gastric Epithelial Cells

J. Gaddy, T. Cover, D. Merrell, 2012, Front. Cell. Inf. Microbio..

Streptococcus agalactiae Induces Placental Macrophages To Release Extracellular Traps Loaded with Tissue Remodeling Enzymes via an Oxidative Burst-Dependent Mechanism

D. Aronoff, J. Gaddy, L. Rogers, 2018, mBio.

Streptococcus agalactiae induces placental macrophages to release extracellular traps loaded with tissue remodeling enzymes via an oxidative-burst-dependent mechanism

D. Aronoff, J. Gaddy, L. Rogers, 2018, bioRxiv.

Title : Ablation of Sam50 is associated with fragmentation and alterations in metabolism in human myotubes

J. Gaddy, J. Shao, Prasanna Katti, 2023 .

Identification of Potential Virulence Factors in the Model Strain Acinetobacter baumannii A118

M. Adams, J. Gaddy, R. Bonomo, 2019, Front. Microbiol..

Control of gene expression in Helicobacter pylori using the Tet repressor.

J. Gaddy, M. S. McClain, T. Cover, 2013, Journal of microbiological methods.

The innate immune protein calprotectin promotes Pseudomonas aeruginosa and Staphylococcus aureus interaction

Catherine A. Wakeman, Eric P. Skaar, R. Caprioli, 2016, Nature Communications.

Regulation of Helicobacter pylori Virulence Within the Context of Iron Deficiency.

J. Gaddy, T. Cover, R. Peek, 2015, The Journal of infectious diseases.

Regulation of Helicobacter Pylori Virulence within the Context of Iron Deficiency Immunofluorescence and Confocal and Scanning Electron Microscopy

J. Gaddy, T. Cover, R. Peek, 2022 .

Ablation of Sam50 is associated with fragmentation and alterations in metabolism in murine and human myotubes

J. Gaddy, J. Shao, Melanie R. McReynolds, 2023, bioRxiv.

Components of Isolated Skeletal Muscle Differentiated Through Antibody Validation

J. Gaddy, Zer Vue, Kit Neikirk, 2023, bioRxiv.

Intrapartum antibiotic prophylaxis selects for mutators in group B streptococci among persistently colonized patients

J. Gaddy, S. Manning, M. E. Pell, 2024, bioRxiv.