A. Herbert

A. Herbert, P. Roberts, Yufang Yang, 2009, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Cooperativity Enables Non-neutralizing Antibodies to Neutralize Ebolavirus

J. Dye, A. Herbert, A. Kuehne, 2017, Cell Reports.

Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2

J. Dye, A. Herbert, E. Procko, 2020, Science.

Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody

Lisa E. Gralinski, J. Dye, D. Burton, 2021, Science.

Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19

Samantha E. Zak, Christopher P Stefan, Jeffrey R. Kugelman, 2022, Antimicrobial Agents and Chemotherapy.

Cysteine Cathepsin Inhibitors as Anti-Ebola Agents.

J. Dye, M. Bogyo, A. Herbert, 2016, ACS infectious diseases.

The SARS-CoV-2 monoclonal antibody combination, AZD7442, is protective in non-human primates and has an extended half-life in humans

J. Dye, M. Pangalos, A. Herbert, 2022, Science Translational Medicine.

AZD7442 demonstrates prophylactic and therapeutic efficacy in non-human primates and extended half-life in humans

J. Dye, M. Pangalos, A. Herbert, 2021, medRxiv.

A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition

L. Pirofski, J. Dye, J. Daily, 2020, Cell Host & Microbe.

A replication-competent vesicular stomatitis virus for studies of SARS-CoV-2 spike-mediated cell entry and its inhibition

L. Pirofski, J. Dye, J. Daily, 2020, bioRxiv.

Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes

Ilya J. Finkelstein, Jonathan R. McDaniel, Jason J. Lavinder, 2021, Science.

Venezuelan Equine Encephalitis Virus Replicon Particle Vaccine Protects Nonhuman Primates from Intramuscular and Aerosol Challenge with Ebolavirus

Majidat A. Muhammad, Samantha E. Zak, J. Dye, 2013, Journal of Virology.

Production of Potent Fully Human Polyclonal Antibodies against Ebola Zaire Virus in Transchromosomal Cattle

J. Dye, A. Herbert, A. Kuehne, 2016, Scientific Reports.

Production of potent fully human polyclonal antibodies against Zaire Ebola virus in transchromosomal cattle

J. Dye, A. Herbert, A. Kuehne, 2015 .

Cytokine-bearing Influenza Vaccine: Adjuvant Potential of Membrane-bound Immunomodulators

A. Herbert, 2009 .

Calcium Regulation of Hemorrhagic Fever Virus Budding: Mechanistic Implications for Host-Oriented Therapeutic Intervention

J. Dye, Jianhong Lu, Ziying Han, 2015, PLoS pathogens.

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion

J. Dye, A. Herbert, K. Chandran, 2015, mBio.

Niemann-Pick C1 Is Essential for Ebolavirus Replication and Pathogenesis In Vivo

J. Dye, A. Herbert, A. Kuehne, 2015, mBio.

Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy

Samantha E. Zak, J. Dye, A. Herbert, 2021, International Journal of Biological Macromolecules.

Postexposure antibody prophylaxis protects nonhuman primates from filovirus disease

Majidat A. Muhammad, Samantha E. Zak, J. Dye, 2012, Proceedings of the National Academy of Sciences.

Filovirus RefSeq Entries: Evaluation and Selection of Filovirus Type Variants, Type Sequences, and Names

Jens H. Kuhn, Ralf G. Dietzgen, J. Rodney Brister, 2014, Viruses.

Lassa virus entry requires a trigger-induced receptor switch

Timothy K. Soh, J. Dye, M. Raaben, 2014, Science.

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates.

Dafna M. Abelson, J. Dye, A. Herbert, 2019, Cell host & microbe.

A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus.

D. Lauffenburger, J. Dye, Jishnu Das, 2018, Cell host & microbe.

Longitudinal peripheral blood transcriptional analysis of a patient with severe Ebola virus disease

J. Dye, K. Walters, D. Baxter, 2017, Science Translational Medicine.

Protocadherin-1 is essential for cell entry by New World hantaviruses

J. Moffat, J. Dye, A. Herbert, 2018, Nature.

Protective neutralizing antibodies from human survivors of Crimean-Congo hemorrhagic fever

Dafna M. Abelson, J. Dye, A. Herbert, 2021, Cell.

NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.

J. Dye, M. Raaben, A. Herbert, 2017, Cell host & microbe.

Niemann-Pick C1 (NPC1)/NPC1-like1 Chimeras Define Sequences Critical for NPC1’s Function as a Filovirus Entry Receptor

J. Dye, A. Herbert, S. Whelan, 2012, Viruses.

Ebola virus entry requires the host‐programmed recognition of an intracellular receptor

J. Dye, G. Ruthel, J. Carette, 2012, The EMBO journal.

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection

J. Dye, D. Burton, J. Theiler, 2018, Cell.

Antibody Treatment of Ebola and Sudan Virus Infection via a Uniquely Exposed Epitope within the Glycoprotein Receptor-Binding Site

J. Dye, A. Herbert, K. Chandran, 2016, Cell Reports.

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles

J. Dye, J. Carette, M. Raaben, 2016, mSphere.

Two-antibody pan-ebolavirus cocktail confers broad therapeutic protection in ferrets and nonhuman primates

Dafna M. Abelson, J. Dye, A. Herbert, 2018, bioRxiv.

Pan-ebolavirus and Pan-filovirus Mouse Monoclonal Antibodies: Protection against Ebola and Sudan Viruses

Jonathan R. Lai, Galit Alter, Marnie L. Fusco, 2015, Journal of Virology.

Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail

Samantha E. Zak, J. Dye, A. Herbert, 2018, Viruses.

Structural Basis of Broad Ebolavirus Neutralization by a Human Survivor Antibody

J. Dye, A. Herbert, K. Chandran, 2019, Nature Structural & Molecular Biology.

Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses

Dafna M. Abelson, J. Dye, A. Herbert, 2017, Cell.

Novel Small Molecule Entry Inhibitors of Ebola Virus.

J. Dye, A. Herbert, K. Chandran, 2015, The Journal of infectious diseases.

NRP 2 and CD 63 Are Host Factors for Lujo Virus Cell Entry Graphical

J. Dye, M. Raaben, A. Herbert, 2022 .

Development of a Human Antibody Cocktail that DeploysMultiple Functions toConfer Pan-Ebolavirus Protection Graphical

Dafna M. Abelson, J. Dye, A. Herbert, 2019 .

Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein

J. Dye, A. Herbert, Pamela J. Glass, 2015, Journal of Virology.

Two Distinct Lysosomal Targeting Strategies Afford Trojan Horse Antibodies With Pan-Filovirus Activity

J. Dye, A. Herbert, A. Kuehne, 2021, Frontiers in Immunology.

Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays

Samantha E. Zak, David J. Ilc, J. Dye, 2021, Methods.

Antibody Response to SARS-CoV-2 Infection and Vaccination in COVID-19-naïve and Experienced Individuals

J. Dye, A. Herbert, G. Reid, 2022, Viruses.

A Combination of Receptor-Binding Domain and N-Terminal Domain Neutralizing Antibodies Limits the Generation of SARS-CoV-2 Spike Neutralization-Escape Mutants

J. Dye, J. Daily, A. Herbert, 2021, mBio.

Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality

Ilya J. Finkelstein, Thomas H. Segall-Shapiro, R. A. Hughes, 2021, bioRxiv.

Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening and in vitro assays

Samantha E. Zak, David J. Ilc, J. Dye, 2020 .

A “Trojan horse” bispecific-antibody strategy for broad protection against ebolaviruses

J. Dye, A. Herbert, A. Kuehne, 2016, Science.

Broad sarbecovirus neutralizing antibodies define a key site of vulnerability on the SARS-CoV-2 spike protein

J. Dye, D. Burton, R. Baric, 2020, bioRxiv.

Development of an antibody cocktail for treatment of Sudan virus infection

Samantha E. Zak, J. Dye, A. Herbert, 2020, Proceedings of the National Academy of Sciences.

Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets

J. Dye, A. Herbert, C. Hill, 2015, Protein science : a publication of the Protein Society.

Antiviral evaluation of hydroxyethylamine analogs: Inhibitors of SARS-CoV-2 main protease (3CLpro), a virtual screening and simulation approach

Poonam, Samantha E. Zak, J. Dye, 2021, Bioorganic & Medicinal Chemistry.

Protocadherin-1 is essential for cell entry by New World hantaviruses

J. Moffat, J. Dye, A. Herbert, 2018, Nature.

A novel compound active against SARS-CoV-2 targeting uridylate-specific endoribonuclease (NendoU/NSP15): in silico and in vitro investigations.

Samantha E. Zak, J. Dye, A. Herbert, 2021, RSC medicinal chemistry.

Characterization of an Anti-Ebola virus Hyperimmune Globulin Derived from Convalescent Plasma.

J. Dye, A. Herbert, V. Arora, 2021, Journal of Infectious Diseases.

Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody

Dafna M. Abelson, Steven B. Bradfute, J. Dye, 2023, Science Translational Medicine.

Molecular modelling predicts SARS-CoV-2 ORF8 protein and human complement Factor 1 catalytic domain sharing common binding site on complement C3b

Caio A. S. Coelho, J. Dye, F. Pasquier, 2020 .

Prophylactic Administration of the Monoclonal Antibody Adintrevimab Protects against SARS-CoV-2 in Hamster and Non-Human Primate Models of COVID-19

Samantha E. Zak, Christopher P Stefan, Jeffrey R. Kugelman, 2022, Antimicrobial Agents and Chemotherapy.

A combination of RBD and NTD neutralizing antibodies limits the generation of SARS-CoV-2 spike neutralization-escape mutants

J. Dye, J. Daily, A. Herbert, 2021, bioRxiv.

Structural Basis of Broad Ebolavirus Neutralization by a Human Survivor Antibody

J. Dye, A. Herbert, E. Saphire, 2018, bioRxiv.

Human antibody cocktail deploys multiple functions to confer pan-ebolavirus protection

Dafna M. Abelson, J. Dye, A. Herbert, 2018, bioRxiv.

Vesicular Stomatitis Virus Pseudotyped with Ebola Virus Glycoprotein Serves as a Protective, Noninfectious Vaccine against Ebola Virus Challenge in Mice

P. T. Ten Eyck, J. Dye, A. Herbert, 2017, Journal of Virology.

Antibodies from a Human Survivor Define Sites of Vulnerability for Broad Protection against Ebolaviruses

Dafna M. Abelson, J. Dye, A. Herbert, 2017, Cell.

SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode

Thomas H. Segall-Shapiro, E. Marcotte, J. Dye, 2023, Communications biology.

Design and characterization of protective pan-ebolavirus and pan-filovirus bispecific antibodies

Dafna M. Abelson, J. Dye, A. Herbert, 2024, PLoS pathogens.

Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection

J. Dye, S. Almo, A. Herbert, 2023, Nature communications.