G. Hicks

发表

Functional genomics in mice by tagged sequence mutagenesis

H. Ruley, G. Hicks, E. Shi, 1997, Nature Genetics.

miR-34 miRNAs provide a barrier for somatic cell reprogramming

Yong Jin Choi, Pengcheng Bu, Geoffrey G. Hicks, 2011, Nature Cell Biology.

Regulation of the cellular DNA double-strand break response.

G. Hicks, Kendra L Cann, 2007, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Absence of an Immediate G1/S Checkpoint in Primary MEFs Following γ-irradiation Identifies a Novel Checkpoint Switch

G. Hicks, Kendra L Cann, 2006, Cell cycle.

The High-Mobility-Group Box Protein SSRP1/T160 Is Essential for Cell Viability in Day 3.5 Mouse Embryos

H. Sakano, H. Ruley, G. Hicks, 2003, Molecular and Cellular Biology.

The Canadian Rare Diseases Models and Mechanisms (RDMM) Network: Connecting Understudied Genes to Model Organisms.

E. Shoubridge, C. Rankin, P. Pavlidis, 2020, American journal of human genetics.

The mammalian gene function resource: the international knockout mouse consortium

Steve D. M. Brown, Hamsa D. Tadepally, Mark W. Moore, 2012, Mammalian Genome.

Genomic Analysis of Localized High-Risk Prostate Cancer Circulating Tumor Cells at the Single-Cell Level

G. Hicks, S. Mai, R. Ouellette, 2020, Cells.

Activation of cryptic 3' splice sites within introns of cellular genes following gene entrapment.

Jason H. Moore, H. Ruley, G. Hicks, 2004, Nucleic acids research.

FUS/TLS acts as an aggregation-dependent modifier of polyglutamine disease model mice

G. Sobue, G. Hicks, N. Hattori, 2016, Scientific Reports.

Retrovirus gene traps.

H. Ruley, G. Hicks, E. Shi, 1995, Methods in enzymology.

Genome-Wide Transcriptome Landscape of Embryonic Brain-Derived Neural Stem Cells Exposed to Alcohol with Strain-Specific Cross-Examination in BL6 and CD1 Mice

G. Hicks, J. Davie, Wayne Xu, 2019, Scientific Reports.

Budget Impact Analysis of an Epigenetic Test Used for Diagnosing Fetal Alcohol Spectrum Disorder from the Perspective of a Laboratory Budget Holder in Manitoba, Canada

G. Hicks, W. Ungar, Jennifer D. Zwicker, 2021, PharmacoEconomics - Open.

Integration of Friend murine leukemia virus into both alleles of the p53 oncogene in an erythroleukemic cell line

G. Hicks, M. Mowat, 1988, Journal of virology.

FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis

T. Hashikawa, G. Hicks, N. Hattori, 2015, Acta Neuropathologica Communications.

ALS-Associated FUS Mutations Result in Compromised FUS Alternative Splicing and Autoregulation

G. Hicks, Guodong Liu, Songyan Liu, 2013, PLoS genetics.

Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53

H. Ruley, G. Hicks, M. Koury, 1994, Molecular and cellular biology.

The RNA Binding Protein TLS Is Translocated to Dendritic Spines by mGluR5 Activation and Regulates Spine Morphology

G. Hicks, T. Takumi, S. Okabe, 2005, Current Biology.

FUS-regulated RNA metabolism and DNA damage repair

G. Hicks, Songyan Liu, Yueqin Zhou, 2014, Rare diseases.

Evidence for a second cell cycle block at G2/M by p53.

G. Hicks, N. Stewart, M. Mowat, 1995, Oncogene.

Apoptosis in megaloblastic anemia occurs during DNA synthesis by a p53-independent, nucleoside-reversible mechanism.

G. Hicks, J. Price, M. Koury, 2000, Blood.

Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation.

Jiuyong Xie, G. Hicks, Jeffrey H. Miller, 2008, Carcinogenesis.

Insights into retinoic acid deficiency and the induction of craniofacial malformations and microcephaly in fetal alcohol spectrum disorder

G. Hicks, A. Fainsod, Berardino Petrelli, 2019, Genesis.

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

Stephanie C Huelga, Gene W Yeo, Gene W. Yeo, 2012, Nature Neuroscience.

The emerging functions of the p53-miRNA network in stem cell biology

Lin He, G. Hicks, Y. Choi, 2012, Cell cycle.

FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis

T. Hashikawa, G. Hicks, N. Hattori, 2015, Acta neuropathologica communications.

MicroRNA-200b regulates distal airway development by maintaining epithelial integrity

G. Hicks, A. Halayko, R. Keijzer, 2017, Scientific Reports.

Copy number variation in fetal alcohol spectrum disorder.

John Wei, S. Scherer, C. Marshall, 2018, Biochemistry and cell biology = Biochimie et biologie cellulaire.

ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS

C. Shaw, Xiang-Dong Fu, G. Hicks, 2018, Neuron.

TLS, EWS and TAF15: a model for transcriptional integration of gene expression.

G. Hicks, Kendra L Cann, W. J. Law, 2006, Briefings in functional genomics & proteomics.

A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation

M. Iacovino, G. Hicks, R. Gatti, 2020, bioRxiv.

Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death

H. Ruley, G. Hicks, S. Mai, 2000, Nature Genetics.

[17] Retrovirus gene traps

H. Ruley, G. Hicks, E. Shi, 1995 .

Identification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoform

G. Hicks, Yuan Gu, M. Sabbir, 2010, BMC Biology.

Mutant p53 tumor suppressor alleles release ras-induced cell cycle growth arrest

G. Hicks, S. Egan, A. Greenberg, 1991, Molecular and cellular biology.

The IKMC web portal: a central point of entry to data and resources from the International Knockout Mouse Consortium

Songyan Liu, Damian Smedley, Jens Hansen, 2010, Nucleic Acids Res..

The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse

Songyan Liu, Patricia Ruiz, John H. Morris, 2005, Nucleic Acids Res..

Endogenous p53 regulation and function in early stage Friend virus-induced tumor progression differs from that following DNA damage

Matthew D. Miller, H. Ruley, G. Hicks, 1998, Oncogene.

Effects of prenatal alcohol exposure (PAE): insights into FASD using mouse models of PAE.

G. Hicks, J. Weinberg, Berardino Petrelli, 2018, Biochemistry and cell biology = Biochimie et biologie cellulaire.

H2-M Mutant Mice Are Defective in the Peptide Loading of Class II Molecules, Antigen Presentation, and T Cell Repertoire Selection

H. Ruley, G. Hicks, L. Kaer, 1996, Cell.

Effects of Prenatal Alcohol Exposure (PAE): Insights into FASD using PAE Mouse Models

G. Hicks, J. Weinberg, Berardino Petrelli, 2018 .

Translating to the Community (T2C): a protocol paper describing the development of Canada's first social epigenetic FASD biobank.

G. Hicks, B. Elias, A. Hanlon-Dearman, 2018, Biochemistry and cell biology = Biochimie et biologie cellulaire.

A generalizable pre-clinical research approach for orphan disease therapy

Sean Ekins, Kym M Boycott, Mark E Samuels, 2012, Orphanet Journal of Rare Diseases.

Genetically programmed retinoic acid deficiency during gastrulation phenocopies most known developmental defects due to acute prenatal alcohol exposure in FASD

G. Hicks, A. Fainsod, M. Pind, 2023, Frontiers in cell and developmental biology.

ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS

C. Shaw, Xiang-Dong Fu, G. Hicks, 2020, Neuron.