R. Hayden

发表

Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors

C. Bradbury, F. Khanim, R. Hayden, 2005, Leukemia.

Drug Redeployment to Kill Leukemia and Lymphoma Cells by Disrupting SCD1-Mediated Synthesis of Monounsaturated Fatty Acids.

M. Viant, F. Khanim, R. Hayden, 2015, Cancer research.

The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs.

R. Hayden, C. Bunce, M. Drayson, 2003, Cancer research.

The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.

F. Khanim, R. Hayden, C. Bunce, 2009, Mutation research.

Combined bezafibrate and medroxyprogesterone acetate have efficacy without haematological toxicity in elderly and relapsed acute myeloid leukaemia (AML)

J. A. Murray, F. Khanim, R. Hayden, 2010, British journal of haematology.

Supramolecular iron cylinder with unprecedented DNA binding is a potent cytostatic and apoptotic agent without exhibiting genotoxicity.

R. Hayden, C. Bunce, J. Chipman, 2008, Chemistry & biology.

Nm23-h1 indirectly promotes the survival of acute myeloid leukemia blast cells by binding to more mature components of the leukemic clone.

A. Lilly, F. Khanim, R. Hayden, 2011, Cancer research.

Tumor and Stem Cell Biology Nm 23-H 1 Indirectly Promotes the Survival of Acute Myeloid Leukemia Blast Cells by Binding to More Mature Components of the Leukemic Clone

A. Lilly, F. Khanim, R. Hayden, 2011 .

Selective AKR1C3 inhibitors do not recapitulate the anti-leukaemic activities of the pan-AKR1C inhibitor medroxyprogesterone acetate

U. Günther, F. Khanim, R. Hayden, 2014, British Journal of Cancer.

Lycorine sensitizes CD40 ligand-protected chronic lymphocytic leukemia cells to bezafibrate- and medroxyprogesterone acetate-induced apoptosis but dasatanib does not overcome reported CD40-mediated drug resistance

R. Hayden, C. Bunce, M. Drayson, 2010, Haematologica.

In Vitro Studies of the Anti-Leukaemic Activity of Bezafibrate and Medroxyprogesterone Acetate Against Chronic Lymphocytic Leukaemia

R. Hayden, 2010 .

Treatment of chronic lymphocytic leukemia requires targeting of the protective lymph node environment with novel therapeutic approaches

R. Hayden, C. Bunce, M. Drayson, 2012, Leukemia & lymphoma.

Bezafibrate and medroxyprogesterone acetate target resting and CD40L-stimulated primary marginal zone lymphoma and show promise in indolent B-cell non-Hodgkin lymphomas

R. Hayden, C. Bunce, M. Drayson, 2015, Leukemia & lymphoma.

Combined Bezafibrate and Medroxyprogesterone Acetate: Potential Novel Therapy for Acute Myeloid Leukaemia

J. A. Murray, M. Viant, F. Khanim, 2009, PloS one.

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

R. Hayden, C. Bunce, J. Ride, 2009, Cancer research.

Treatment of primary CLL cells with bezafibrate and medroxyprogesterone acetate induces apoptosis and represses the pro-proliferative signal of CD40-ligand, in part through increased 15dΔ12,14,PGJ2

J. Delgado, F. Khanim, R. Hayden, 2009, Leukemia.

PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC.

F. Khanim, R. Hayden, C. Bunce, 2005, Blood.

Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy

F. Khanim, R. Hayden, C. Bunce, 2009, BMC Cell Biology.

Metabolic plasticity in CLL: adaptation to the hypoxic niche

U. Günther, C. Ludwig, F. Khanim, 2015, Leukemia.

Expression of the double-stranded RNA-dependent protein kinase (p68) in human breast tissues.

R. Hayden, M. Talamonti, J. Radosevich, 1996, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

Elevated FOSB‐expression; a potential marker of valproate sensitivity in AML

C. Bradbury, F. Khanim, R. Hayden, 2009, British journal of haematology.

Use of a molecular beacon to track the activity of base excision repair protein OGG1 in live cells.

R. Meldrum, R. Hayden, R. Green, 2010, DNA repair.

University of Birmingham Analysis of the role of COP9 Signalosome (CSN) subunits in K562; the first link between CSN and autophagy

F. Khanim, R. Hayden, C. Bunce, 2009 .

Bmc Cell Biology Analysis of the Role of Cop9 Signalosome (csn) Subunits in K562; the First Link between Csn and Autophagy

F. Khanim, R. Hayden, C. Bunce, 2022 .