H. Kwon

发表

Histone deacetylase in carcinogenesis and its inhibitors as anti-cancer agents.

Dong Hoon Kim, Minjung Kim, H. Kwon, 2003, Journal of biochemistry and molecular biology.

A new curcumin derivative, HBC, interferes with the cell cycle progression of colon cancer cells via antagonization of the Ca2+/calmodulin function.

So-Jung Park, H. Kwon, Hyun-Ju Park, 2004, Chemistry & biology.

Radicicol Binding to Swo1/Hsp90 and Inhibition of Growth of Specific Temperature-sensitive Cell Cycle Mutants of Fission Yeast

H. Kwon, M. Yoshida, S. Horinouchi, 2001, Bioscience, biotechnology, and biochemistry.

Autophagic Inhibition via Lysosomal Integrity Dysfunction Leads to Antitumor Activity in Glioma Treatment

H. Kwon, J. Kim, J. Yoo, 2020, Cancers.

Autophagic Inhibition via Lysosomal Integrity Dysfunction Leads to Antitumor Activity in Glioma Treatment

H. Kwon, J. Kim, J. Yoo, 2020, Cancers.

Rengyolone inhibits inducible nitric oxide synthase expression and nitric oxide production by down-regulation of NF-kappaB and p38 MAP kinase activity in LPS-stimulated RAW 264.7 cells.

Ho Jae Lee, H. Kwon, C. Lee, 2006, Biochemical pharmacology.

Clinical protein science in translational medicine targeting malignant melanoma

H. Olsson, H. Kwon, J. Tímár, 2019, Cell Biology and Toxicology.

The non-provitamin A carotenoid, lutein, inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: role of H(2)O(2) in NF-kappaB activation.

H. Kwon, K. Ha, Chun-Ki Kim, 2008, Free radical biology & medicine.

Cell-permeable mitochondrial ubiquinol-cytochrome c reductase binding protein induces angiogenesis in vitro and in vivo.

Seung‐Woo Cho, H. Kwon, Hyun-Ji Park, 2015, Cancer letters.

Extract of high hydrostatic pressure-treated danshen (Salvia miltiorrhiza) ameliorates atherosclerosis via autophagy induction

H. Kwon, Jiyong Park, G. Oh, 2020, BMB reports.

Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway

Jun O. Liu, H. Kwon, S. Kang, 2016, Scientific Reports.

Exploring the role of mitochondrial UQCRB in angiogenesis using small molecules.

H. Kwon, H. Jung, 2013, Molecular bioSystems.

Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham

H. Kwon, J. T. Kim, Seung Wook Kim, 2017, Korean journal for food science of animal resources.

Anti-parasitic activity of depudecin on Neospora caninum via the inhibition of histone deacetylase.

Minjung Kim, H. Kwon, W. Hwang, 2003, Veterinary parasitology.

Reduction of hypoxia-induced transcription through the repression of hypoxia-inducible factor-1alpha/aryl hydrocarbon receptor nuclear translocator DNA binding by the 90-kDa heat-shock protein inhibitor radicicol.

H. Kwon, Hong-Hee Kim, E. Hur, 2002, Molecular pharmacology.

Modified Oligonucleotides Containing Lithocholic Acid in Their Backbones: Their Enhanced Cellular Uptake and Their Mimicking of Hairpin Structures

H. Kwon, J. Shim, B. Kim, 2004, Chembiochem : a European journal of chemical biology.

A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes

H. Kwon, Jin-Hee Ahn, Myung-Shik Lee, 2018, Nature Communications.

Approaches for discovering novel bioactive small molecules targeting autophagy

H. Kwon, Hui-Yun Hwang, S. Cho, 2017, Expert opinion on drug discovery.

Mutational biosynthesis of a FK506 analogue containing a non-natural starter unit.

H. Kwon, Jong Hyun Lee, Y. Yoon, 2013, Molecular bioSystems.

Potential anti‐cancer activity of N‐hydroxy‐7‐(2‐naphthylthio) heptanomide (HNHA), a histone deacetylase inhibitor, against breast cancer both in vitro and in vivo

H. Kwon, J. H. Park, H. Chung, 2011, Cancer science.

4-O-Methylgallic acid suppresses inflammation-associated gene expression by inhibition of redox-based NF-kappaB activation.

H. Kwon, K. Ha, Young-Guen Kwon, 2006, International immunopharmacology.

The Hidden Story of Heterogeneous B-raf V600E Mutation Quantitative Protein Expression in Metastatic Melanoma—Association with Clinical Outcome and Tumor Phenotypes

H. Olsson, H. Kwon, D. Fenyö, 2019, Cancers.

The Hidden Story on Heterogeneous B-raf V600E Mutation Quantitative Protein Expression in Metastatic Melanoma – Association with Clinical Outcome and Tumor Phenotypes

H. Olsson, H. Kwon, D. Fenyö, 2019 .

DNA Polymerase Alpha Subunit B Is a Binding Protein for Erlotinib Resistance in Non-Small Cell Lung Cancer

H. Kwon, G. Marko‐Varga, J. Kim, 2020, Cancers.

Development of a novel class of mitochondrial ubiquinol-cytochrome c reductase binding protein (UQCRB) modulators as promising antiangiogenic leads.

H. Kwon, G. Han, H. Jung, 2014, Journal of medicinal chemistry.

Matairesinol inhibits angiogenesis via suppression of mitochondrial reactive oxygen species.

H. Kwon, H. Jung, Boram Lee, 2012, Biochemical and biophysical research communications.

Identification of a novel small molecule targeting UQCRB of mitochondrial complex III and its anti-angiogenic activity.

H. Kwon, G. Han, H. Jung, 2011, Bioorganic & medicinal chemistry letters.

A Novel Ca2+/Calmodulin Antagonist HBC Inhibits Angiogenesis and Down-regulates Hypoxia-inducible Factor*

H. Kwon, J. Shim, H. Jung, 2010, The Journal of Biological Chemistry.

Cochlioquinone A1, a new anti-angiogenic agent from Bipolaris zeicola.

H. Kwon, H. Jung, C. Lim, 2003, Bioorganic & medicinal chemistry.

Anti-angiogenic activity of terpestacin, a bicyclo sesterterpene from Embellisia chlamydospora.

H. Kwon, H. Lee, J. Rho, 2003, The Journal of antibiotics.

Mitochondrial ROS Produced in Human Colon Carcinoma Associated with Cell Survival via Autophagy

H. Kwon, Hui-Yun Hwang, Eun-Ji Gwak, 2022, Cancers.

Profiling the Protein Targets of Unmodified Bio‐Active Molecules with Drug Affinity Responsive Target Stability and Liquid Chromatography/Tandem Mass Spectrometry

H. Kwon, J. Malm, G. Marko‐Varga, 2020, Proteomics.

Biobank integration of large-scale clinical and histopathology melanoma studies within the European Cancer Moonshot Lund Center

H. Kwon, J. Malm, G. Marko‐Varga, 2018, Clinical and Translational Medicine.

Radicicol Binding to Swol / Hsp 90 and Inhibition of Temperature-sensitive Cell Cycle Mutants of FissionGrowth of Specific Yeas

H. Kwon, S. Yoshida, S. W. Ki, 2017 .

HIF-1α suppressing small molecule, LW6, inhibits cancer cell growth by binding to calcineurin b homologous protein 1.

H. Kwon, H. Jung, Kyeong Lee, 2015, Biochemical and biophysical research communications.

NNC 55-0396, a T-type Ca2+ channel inhibitor, inhibits angiogenesis via suppression of hypoxia-inducible factor-1α signal transduction

H. Kwon, Jin Han, Kang-Yell Choi, 2014, Journal of Molecular Medicine.

Cryptotanshinone but not tanshinone IIA inhibits angiogenesis in vitro

H. Kwon, J. Shim, H. Jung, 2005, Experimental & Molecular Medicine.

Building the basis for proteomics in personalized medicine for targeted treatment

H. Kwon, G. Marko‐Varga, T. Fehniger, 2016, Clinical and Translational Medicine.

Association of sustained ERK activity with integrin beta3 induction during receptor activator of nuclear factor kappaB ligand (RANKL)-directed osteoclast differentiation.

Sakae Tanaka, H. Kwon, Hong-Hee Kim, 2003, Experimental cell research.

Aminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3.

H. Kwon, J. Shim, H. Woo, 2007, Biochemical and biophysical research communications.

N-hydroxy-2-(naphthalene-2-ylsulfanyl)-acetamide, a novel hydroxamic acid-based inhibitor of aminopeptidase N and its anti-angiogenic activity.

H. Kwon, J. Shim, Jiyong Lee, 2005, Bioorganic & medicinal chemistry letters.

Psammaplin A, a marine natural product, inhibits aminopeptidase N and suppresses angiogenesis in vitro.

H. Kwon, J. Shim, Hyi-Seung Lee, 2004, Cancer letters.

Irreversible inhibition of CD13/aminopeptidase N by the antiangiogenic agent curcumin.

H. Kwon, B. Shim, Hyun-Ju Park, 2003, Chemistry & biology.

Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking

Jun O. Liu, H. Kwon, W. Ge, 2018, International journal of biological sciences.

Potent and specific inhibition of p60v-src protein kinase both in vivo and in vitro by radicicol.

H. Kwon, M. Yoshida, S. Horinouchi, 1992, Cancer research.

Identification and Validation of VEGFR2 Kinase as a Target of Voacangine by a Systematic Combination of DARTS and MSI

H. Kwon, G. Marko‐Varga, M. Rezeli, 2020, Biomolecules.

Advances in identification and validation of protein targets of natural products without chemical modification.

H. Kwon, Junghwa Chang, J. Chang, 2016, Natural product reports.

Proteomic analysis of microvesicles derived from human colorectal cancer cells.

H. Kwon, Y. Gho, Yoon-Keun Kim, 2007, Journal of proteome research.

Inhibition of histone deacetylase1 induces autophagy.

H. Kwon, Meeyeon Oh, In-kwon Choi, 2008, Biochemical and biophysical research communications.

Discovery of gliotoxin as a new small molecule targeting thioredoxin redox system.

H. Kwon, S. Kang, J. Shim, 2007, Biochemical and biophysical research communications.

Reverse Chemical Proteomics Identifies an Unanticipated Human Target of the Antimalarial Artesunate.

H. Kwon, M. Gotsbacher, P. Karuso, 2019, ACS chemical biology.

The effect of xanthorrhizol on the expression of matrix metalloproteinase‐1 and type‐I procollagen in ultraviolet‐irradiated human skin fibroblasts

H. Kwon, Jae-Kwan Hwang, J. Shim, 2009, Phytotherapy research : PTR.

Trichostatin A Exacerbates Atherosclerosis in Low Density Lipoprotein Receptor–Deficient Mice

H. Kwon, Hyun-Young Park, G. Oh, 2005, Arteriosclerosis, thrombosis, and vascular biology.

SIMPL Is a Tumor Necrosis Factor-specific Regulator of Nuclear Factor-κB Activity*

M. Goebl, H. Kwon, Y. Liu, 2001, The Journal of Biological Chemistry.

Activation of Ca2+‐AMPK‐mediated autophagy by ginsenoside Rg3 attenuates cellular senescence in human dermal fibroblasts

H. Kwon, Hui-Yun Hwang, Jinyoung Kim, 2021, Clinical and translational medicine.

Property-based optimization of hydroxamate-based γ-lactam HDAC inhibitors to improve their metabolic stability and pharmacokinetic profiles.

H. Kwon, S. Oh, Jee Sun Yang, 2012, Journal of medicinal chemistry.

Microarray‐based Analysis of Anti‐angiogenic Activity of Demethoxycurcumin on Human Umbilical Vein Endothelial Cells: Crucial Involvement of the Down‐regulation of Matrix Metalloproteinase

H. Kwon, J. Shim, Kyu-Won Kim, 2002, Japanese journal of cancer research : Gann.

Downregulation of melanin synthesis by haginin A and its application to in vivo lightening model.

H. Kwon, C. Lee, S. Baek, 2008, The Journal of investigative dermatology.

Downregulation of gelsolin and retinoic acid receptor β expression in gastric cancer tissues through histone deacetylase 1

H. Kwon, D. Kim, Jin‐Hyun Kim, 2004, Journal of gastroenterology and hepatology.

Inhibition of 5-lipoxygenase suppresses vascular endothelial growth factor-induced angiogenesis in endothelial cells.

H. Kwon, H. Y. Choo, Tae Young Kim, 2016, Biochemical and biophysical research communications.

A biobanking turning‐point in the use of formalin‐fixed, paraffin tumor blocks to unveil kinase signaling in melanoma

H. Kwon, J. Malm, G. Marko‐Varga, 2021, Clinical and translational medicine.

Development of a new Ca2+/calmodulin antagonist and its anti-proliferative activity against colorectal cancer cells.

H. Kwon, J. Shim, Jiyong Lee, 2007, Biochemical and biophysical research communications.

Functional analysis of a histone deacetylase-like protein of Thermus caldophilus GK24 in mammalian cell.

H. Kwon, You Sun Kim, Y. Song, 2007, Biochemical and biophysical research communications.

Structure and expression of the rice class-I type histone deacetylase genes OsHDAC1-3: OsHDAC1 overexpression in transgenic plants leads to increased growth rate and altered architecture.

H. Kwon, S. Song, Jukon Kim, 2003, The Plant journal : for cell and molecular biology.

Control of autophagy with small molecules

H. Kwon, Yoon Sun Cho, 2010, Archives of pharmacal research.

Cell cycle inhibitory activity of 4-hydroxy-3-(3'-methyl-2'-butenyl)-benzoic acid from Curvularia sp. KF119.

H. Kwon, J. Shim, I. Yoo, 2004, The Journal of antibiotics.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Identification and biological activities of a new antiangiogenic small molecule that suppresses mitochondrial reactive oxygen species.

H. Kwon, H. Jung, Ju Yeol Park, 2011, Biochemical and biophysical research communications.

Radicicol, a Protein Tyrosine Kinase Inhibitor, Suppresses the Expression of Mitogen-inducible Cyclooxygenase in Macrophages Stimulated with Lipopolysaccharide and in Experimental Glomerulonephritis (*)

H. Kwon, B. Jang, Minoru Yoshida, 1995, The Journal of Biological Chemistry.

Proteomic analyses reveal that ginsenoside Rg3(S) partially reverses cellular senescence in human dermal fibroblasts by inducing peroxiredoxin

H. Kwon, I. Jang, Je‐ho Lee, 2018, Journal of ginseng research.

Development of Novel VEGFR2 Inhibitors Originating from Natural Product Analogues with Antiangiogenic Impact.

H. Kwon, G. Marko‐Varga, Yonghyo Kim, 2021, Journal of medicinal chemistry.

Hepatic steatosis in transgenic mice overexpressing human histone deacetylase 1.

Dong Hoon Kim, H. Kwon, H. Moon, 2005, Biochemical and biophysical research communications.

Identification of proteomic landscape of drug-binding proteins in live cells by proximity-dependent target ID.

H. Kwon, S. Kim, J. Seo, 2022, Cell chemical biology.

Turmeric extract and its active compound, curcumin, protect against chronic CCl4-induced liver damage by enhancing antioxidation

H. Kwon, H. Chae, Hwa-Young Lee, 2016, BMC Complementary and Alternative Medicine.

Convallatoxin, a Dual Inducer of Autophagy and Apoptosis, Inhibits Angiogenesis In Vitro and In Vivo

H. Kwon, N. Kim, Yoon Sun Cho, 2014, PloS one.

Functional inhibition of fatty acid binding protein 4 ameliorates impaired ciliogenesis in GCs.

H. Kwon, J. Cheong, Sungsoo Kim, 2021, Biochemical and Biophysical Research Communications - BBRC.

Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress

H. Kwon, Hyung-Ryong Kim, H. Chae, 2017, Scientific Reports.

Gentisyl alcohol inhibits apoptosis by suppressing caspase activity induced by etoposide

H. Kwon, T. Oh, M. Kim, 2005 .

Mitochondrial ROS Produced in Human Colon Carcinoma HCT116 Cells Reduces Cell Survival via Autophagy

H. Kwon, Hui-Yun Hwang, Dasol Kim, 2022 .

Proteogenomic Characterization Reveals Therapeutic Opportunities Related to Mitochondrial Function in Melanoma

H. Kwon, D. Fenyö, J. Tímár, 2022, bioRxiv.

Eupatilin rescues ciliary transition zone defects to ameliorate ciliopathy-related phenotypes

H. Kwon, Sungsoo Kim, Yong Joon Kim, 2018, The Journal of clinical investigation.

Morphology of ras-transformed cells becomes apparently normal again with tyrosine kinase inhibitors without a decrease in the ras-GTP complex.

H. Kwon, E. Nishida, M. Yoshida, 1995, Journal of biochemistry.

Identification of EBP50 as a specific biomarker for carcinogens via the analysis of mouse lymphoma cellular proteome

H. Kwon, Sue-N. Park, Y. Sheen, 2012, Molecules and cells.

The Second Asia-Oceania Human Proteome Organization (AOHUPO) Online Education Series on the Renaissance of Clinical Proteomics: Biomarkers, Imaging and Therapeutics

H. Kwon, Y. Ishihama, S. Cordwell, 2022, Molecular & cellular proteomics : MCP.

Sphingosine 1-phosphate stimulates tyrosine phosphorylation of focal adhesion kinase and chemotactic motility of endothelial cells via the G(i) protein-linked phospholipase C pathway.

H. Kwon, K. W. Kim, O. Lee, 2000, Biochemical and biophysical research communications.

Mitochondrial UQCRB regulates VEGFR2 signaling in endothelial cells

H. Kwon, S. Kang, J. H. Kim, 2013, Journal of Molecular Medicine.

NNC 55-0396, a T-type Ca2+ channel inhibitor, inhibits angiogenesis via suppression of hypoxia-inducible factor-1α signal transduction

H. Kwon, Jin Han, Kang-Yell Choi, 2015, Journal of Molecular Medicine.

Chemical proteomics, an integrated research engine for exploring drug-target-phenotype interactions

H. Kwon, P. Karuso, 2018, Proteome Science.

Upregulation of SNAP25 by HDAC inhibition ameliorates Niemann‐Pick Type C disease phenotypes via autophagy induction

H. Kwon, Insung Kang, Seung-Eun Lee, 2022, Clinical and translational medicine.

A non-immunosuppressive FK506 analogue with neuroregenerative activity produced from a genetically engineered Streptomyces strain

H. Kwon, S. Nam, Y. Yoon, 2015 .

Anti-Angiogenic Activity of a Homoisoflavanone from cremastra appendiculata

Jin Hee Kim, Ho Jeong Kwon, H. Kwon, 2004, Planta medica.

Targeting Autophagy In Disease: Recent Advances In Drug Discovery

H. Kwon, Hui-Yun Hwang, Dasol Kim, 2020, Expert opinion on drug discovery.

Design, synthesis, and biological evaluation of novel pyrrolo[1,2-a]pyrazine derivatives.

H. Kwon, Jiwon Choi, D. Singh, 2019, Bioorganic & medicinal chemistry letters.

Two cyclic hexapeptides from Penicillium sp. FN070315 with antiangiogenic activities

H. Kwon, Jae-Hyuk Jang, J. Ahn, 2017, PloS one.

Antiangiogenic activity of 4-O-methylgallic acid from Canavalia gladiata, a dietary legume.

H. Kwon, Young-Myeong Kim, Hee-Jun Na, 2005, Biochemical and biophysical research communications.

Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans

H. Kwon, M. Gotsbacher, P. Karuso, 2016, Proteome Science.

The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway.

H. Kwon, Bokyung Kim, Hwa-Sup Shin, 2014, Experimental cell research.

A natural small molecule voacangine inhibits angiogenesis both in vitro and in vivo.

H. Kwon, H. Jung, Yonghyo Kim, 2012, Biochemical and biophysical research communications.

Verrulactones A and B, new inhibitors of Staphylococcus aureus enoyl-ACP reductase produced by Penicillium verruculosum F375.

H. Kwon, M. Sohn, Won-Gon Kim, 2012, Bioorganic & medicinal chemistry letters.

Verrulactones A and B, New Inhibitors of Staphylococcus aureus Enoyl‐ACP Reductase Produced by Penicillium verruculosum F375.

H. Kwon, M. Sohn, Won-Gon Kim, 2012 .

A new synthetic analogue of thymidine, 7-(3-bromo-phenoxy)-thymidine, inhibits the proliferation of tumor cells.

Dong Hoon Kim, H. Kwon, J. Yoo, 2005, Bioorganic & medicinal chemistry letters.

Purification and Properties of d-Xylose Isomerase from Alkalophilic Bacillus No. KX-6

H. Kwon, K. Horikoshi, M. Kitada, 1987 .

Synthesis of (Ti, M1, M2)(CN)–Ni nanocrystalline powders

H. Kwon, Sunhoo Park, S. Kang, 2006 .

The Human Melanoma Proteome Atlas—Complementing the melanoma transcriptome

H. Kato, P. Horváth, H. Kwon, 2021, Clinical and translational medicine.

Optimization of β-Cyclodextrin Recycling Process for Cholesterol Removal in Cream

H. Kwon, H. Kwak, J. Ahn, 2001 .

Drug compound characterization by mass spectrometry imaging in cancer tissue

B. Döme, H. Kwon, J. Malm, 2015, Archives of Pharmacal Research.

Drug compound characterization by mass spectrometry imaging in cancer tissue

B. Döme, H. Kwon, J. Malm, 2015, Archives of pharmacal research.

Enhanced production of clavulanic acid by improving glycerol utilization using reporter-guided mutagenesis of an industrial Streptomyces clavuligerus strain

H. Kwon, Y. Yoon, Chan‐Wha Kim, 2021, Journal of industrial microbiology & biotechnology.

Focal adhesion kinase regulates syndecan-2-mediated tumorigenic activity of HT1080 fibrosarcoma cells.

H. Kwon, E. Oh, Haein Park, 2005, Cancer research.

Decreased syndecan-2 expression correlates with trichostatin-A induced-morphological changes and reduced tumorigenic activity in colon carcinoma cells

H. Kwon, Y. Lim, A. Woods, 2003, Oncogene.

Discovery of Pyridone‐Based Histone Deacetylase Inhibitors: Approaches for Metabolic Stability

H. Kwon, S. Oh, Jee Sun Yang, 2013, ChemMedChem.

Protein Expression in Metastatic Melanoma and the Link to Disease Presentation in a Range of Tumor Phenotypes

H. Olsson, H. Kwon, C. Ingvar, 2020, Cancers.

Streptochlorin, a marine natural product, inhibits NF-kappaB activation and suppresses angiogenesis in vitro.

H. Kwon, Hyi-Seung Lee, H. Shin, 2007, Journal of microbiology and biotechnology.

Streptopyrrolidine, an angiogenesis inhibitor from a marine-derived Streptomyces sp. KORDI-3973.

H. Kwon, Hyi-Seung Lee, H. Shin, 2008, Phytochemistry.

An angiogenesis inhibitor isolated from a marine-derived actinomycete, Nocardiopsis sp. 03N67

H. Kwon, Hyi-Seung Lee, Yeon-Ju Lee, 2010 .

Downregulation of mitochondrial UQCRB inhibits cancer stem cell-like properties in glioblastoma.

H. Kwon, H. Jung, Narae Jung, 2017, International journal of oncology.

Activation of mitochondrial TUFM ameliorates metabolic dysregulation through coordinating autophagy induction

H. Kwon, J. Kim, J. Yoo, 2021, Communications Biology.

The human melanoma proteome atlas—Defining the molecular pathology

H. Kato, H. Olsson, P. Horváth, 2021, Clinical and translational medicine.

Antidepressant drug sertraline modulates AMPK-MTOR signaling-mediated autophagy via targeting mitochondrial VDAC1 protein

H. Kwon, J. Shim, Hui-Yun Hwang, 2020, Autophagy.

Radicicol, an agent inducing the reversal of transformed phenotypes of src-transformed fibroblasts.

H. Kwon, M. Yoshida, S. Horinouchi, 1992, Bioscience, biotechnology, and biochemistry.

Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice

M. Menon, A. Levin, H. Kwon, 2015, Oncotarget.

Homoharringtonine Induces Apoptosis in Human Colorectal Carcinoma HCT116 Cells Via Downregulation of Wnt/β‐Catenin Signaling Cascade

H. Kwon, S. Kim, Mikyung Park, 2019, Bulletin of the Korean Chemical Society.

Proteomic analysis enables distinction of early‐ versus advanced‐stage lung adenocarcinomas

H. Kwon, J. Malm, G. Marko‐Varga, 2020, Clinical and translational medicine.

FBI-1 Enhances Transcription of the Nuclear Factor-κB (NF-κB)-responsive E-selectin Gene by Nuclear Localization of the p65 Subunit of NF-κB*

H. Kwon, M. Hur, Tae-Hee Yim, 2005, Journal of Biological Chemistry.

Coordinated transcriptional regulation of calmegin, a testis-specific molecular chaperon, by histone deacetylase and CpG methyltransferase

Dong Hoon Kim, H. Kwon, J. Shim, 2005, Experimental & Molecular Medicine.

Histone deacetylases induce angiogenesis by negative regulation of tumor suppressor genes

Eun-Joung Moon, Ho Jeong Kwon, Hae Young Chung, 2001, Nature Medicine.

Tricin, 4',5,7-trihydroxy-3',5'-dimethoxyflavone, exhibits potent antiangiogenic activity in vitro.

H. Kwon, H. Jung, Jang Mi Han, 2016, International journal of oncology.

Matrix‐assisted laser desorption ionization ‐ mass spectrometry imaging of erlotinib reveals a limited tumor tissue distribution in a non‐small‐cell lung cancer mouse xenograft model

H. Kwon, G. Marko‐Varga, M. Rezeli, 2021, Clinical and translational medicine.

FK506, an Immunosuppressive Drug, Induces Autophagy by Binding to the V-ATPase Catalytic Subunit A in Neuronal Cells.

H. Kwon, G. Marko‐Varga, J. Kim, 2017, Journal of proteome research.

Discovery of a small-molecule inhibitor for kidney ADP-ribosyl cyclase: Implication for intracellular calcium signal mediated by cyclic ADP-ribose

H. Kwon, Tae-Sik Nam, So-Young Rah, 2006, Experimental & Molecular Medicine.

Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery

H. Kwon, H. Jung, 2015, Archives of Pharmacal Research.

Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery

Ho Jeong Kwon, Hye Jin Jung, H. Kwon, 2015, Archives of Pharmacal Research.

Identification of genes related to a synergistic effect of taxane and suberoylanilide hydroxamic acid combination treatment in gastric cancer cells

H. Kwon, H. Chung, S. Rha, 2010, Journal of Cancer Research and Clinical Oncology.

Betulinic Acid Inhibits Growth Factor‐induced in vitro Angiogenesis via the Modulation of Mitochondrial Function in Endothelial Cells

H. Kwon, J. Shim, Jin Hee Kim, 2002, Japanese journal of cancer research : Gann.

Daptomycin suppresses tumor migration and angiogenesis via binding to ribosomal protein S19 in humans

H. Kwon, P. Karuso, S. Cho, 2021, The Journal of Antibiotics.

Inactivation of Interferon Regulatory Factor-1 Tumor Suppressor Protein by HPV E7 Oncoprotein

Jong-Sup Park, H. Kwon, S. Namkoong, 2000, The Journal of Biological Chemistry.

Moesin is a biomarker for the assessment of genotoxic carcinogens in mouse lymphoma

H. Kwon, Sue-N. Park, Y. Sheen, 2012, Molecules and cells.

Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues.

Yeo Joon Yoon, Bradley S Moore, Young Ji Yoo, 2011, Journal of the American Chemical Society.

Discovery of novel drug targets and their functions using phenotypic screening of natural products

Ho Jeong Kwon, Junghwa Chang, H. Kwon, 2016, Journal of Industrial Microbiology & Biotechnology.

Purpurin inhibits adipocyte-derived leucine aminopeptidase and angiogenesis in a zebrafish model.

T. Huh, H. Kwon, J. Shim, 2014, Biochemical and biophysical research communications.

Embellistatin, a microtubule polymerization inhibitor, inhibits angiogenesis both in vitro and in vivo.

H. Kwon, M. Ono, J. Shim, 2007, Biochemical and biophysical research communications.

Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation.

Dong Hoon Kim, H. Kwon, J. Yoo, 2002, Bioorganic & medicinal chemistry.

Histone deacetylase inhibitor FK228 inhibits tumor angiogenesis

H. Kwon, Kyu-Won Kim, H. Nakajima, 2002, International journal of cancer.

Trichostatin A induces morphological changes and gelsolin expression by inhibiting histone deacetylase in human carcinoma cell lines.

H. Kwon, M. Yoshida, S. Horinouchi, 1994, Experimental cell research.

Overexpression of metastasis-associated protein 2 is associated with hepatocellular carcinoma size and differentiation

H. Kwon, Y. Chung, Kyu-Won Kim, 2009 .

Anti-tumor activity of N-hydroxy-7-(2-naphthylthio) heptanomide, a novel histone deacetylase inhibitor.

Dong Hoon Kim, H. Kwon, Jiyong Lee, 2007, Biochemical and biophysical research communications.

Expression Profile of Histone Deacetylase 1 in Gastric Cancer Tissues

H. Kwon, B. Yoon, D. Kim, 2001, Japanese journal of cancer research : Gann.

A mutation in the mitochondrial protein UQCRB promotes angiogenesis through the generation of mitochondrial reactive oxygen species.

H. Kwon, Jin Han, H. Jung, 2014, Biochemical and biophysical research communications.

Trichostatin A-induced Detransformation Correlates with Decreased Focal Adhesion Kinase Phosphorylation at Tyrosine 861 inras-transformed Fibroblasts*

H. Kwon, Y. Lim, E. Oh, 2002, The Journal of Biological Chemistry.

The Homeodomain Protein NK-3 Recruits Groucho and a Histone Deacetylase Complex to Repress Transcription*

H. Kwon, Yongsok Kim, C. Choi, 1999, The Journal of Biological Chemistry.

The novel histone deacetylase inhibitor, N-hydroxy-7-(2-naphthylthio) hepatonomide, exhibits potent antitumor activity due to cytochrome-c-release-mediated apoptosis in renal cell carcinoma cells

H. Kwon, K. Park, Kyung Seok Han, 2015, BMC Cancer.

Hydrazinocurcumin, a novel synthetic curcumin derivative, is a potent inhibitor of endothelial cell proliferation.

Dong Hoon Kim, H. Kwon, J. Yoo, 2002, Bioorganic & medicinal chemistry.

Chemical genetics for therapeutic target mining

Ho Jeong Kwon, H. Kwon, J. Shim, 2004, Expert opinion on therapeutic targets.

Identification of radicicol as an inhibitor of in vivo Ras/Raf interaction with the yeast two-hybrid screening system.

Jonathan A. Cooper, H. Kwon, M. Yoshida, 1998, The Journal of antibiotics.

Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells.

H. Kwon, K. Ha, S. Namkoong, 2007, Biological & pharmaceutical bulletin.

Hydroxamic Acid Derivatives of Mycophenolic Acid Inhibit Histone Deacetylase at the Cellular Level

Dong Hoon Kim, H. Kwon, M. Ubukata, 2008, Bioscience, biotechnology, and biochemistry.

Acid ceramidase, an emerging target for anti-cancer and anti-angiogenesis

H. Kwon, S. Cho, 2019, Archives of Pharmacal Research.

Acid ceramidase, an emerging target for anti-cancer and anti-angiogenesis

H. Kwon, S. Cho, 2019, Archives of pharmacal research.

Isolation of Streptomyces sp. KK565 as a Producer of beta-Amyloid Aggregation Inhibitor

Dong Hoon Kim, H. Kwon, J. Yoo, 2003 .

The sphingosine-1-phosphate derivative NHOBTD inhibits angiogenesis both in vitro and in vivo.

H. Kwon, S. Ko, BeomSeok Kim, 2011, Biochemical and biophysical research communications.

Production of Oleamide, a Functional Lipid, by Streptomyces sp. KK90378

H. Kwon, J. Rho, Jongheon Shin, 2001 .

Radicicol represses the transcriptional function of the estrogen receptor by suppressing the stabilization of the receptor by heat shock protein 90

Eun-Ok Kim, Ho Jeong Kwon, H. Kwon, 2002, Molecular and Cellular Endocrinology.

A new anti-angiogenic small molecule, G0811, inhibits angiogenesis via targeting hypoxia inducible factor (HIF)-1α signal transduction.

H. Kwon, H. Jung, K. Kim, 2013, Biochemical and biophysical research communications.

Development of an angiogenesis-focused cDNA chip and validation of its functionality

H. Kwon, J. Shim, E. K. Kim, 2005, Experimental & Molecular Medicine.

Psammaplin A is a natural prodrug that inhibits class I histone deacetylase

Dong Hoon Kim, H. Kwon, Jongheon Shin, 2007, Experimental & Molecular Medicine.

Cloning, expression, and biochemical characterization of a new histone deacetylase-like protein from Thermus caldophilus GK24.

H. Kwon, You Sun Kim, Dooil Kim, 2007, Biochemical and biophysical research communications.

Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110.

H. Kwon, Song-Kyu Park, Hyi-Seung Lee, 2007, Journal of microbiology and biotechnology.

Hot springs and cool natural products.

H. Kwon, Minoru Yoshida, M. Imoto, 2008, Nature chemical biology.

Novel functional proteins coded by the human genome discovered in metastases of melanoma patients

H. Olsson, H. Kwon, C. Ingvar, 2019, Cell Biology and Toxicology.

University of Groningen Novel functional proteins coded by the human genome discovered in metastases of melanoma patients Sanchez,

H. Olsson, H. Kwon, C. Ingvar, 2019 .

Heat Shock Protein 90 Mediates Protein-protein Interactions between Human Aminoacyl-tRNA Synthetases*

H. Kwon, S. Rho, M. Kim, 2000, The Journal of Biological Chemistry.

Probing lysine acetylation with a modification-specific marker ion using high-performance liquid chromatography/electrospray-mass spectrometry with collision-induced dissociation.

Jin Young Kim, Jong Shin Yoo, Ho Jeong Kwon, 2002, Analytical chemistry.

Functional inhibition of UQCRB suppresses angiogenesis in zebrafish.

H. Kwon, Alexander Y. Payumo, James K. Chen, 2013, Biochemical and biophysical research communications.

Mitochondrial UQCRB as a new molecular prognostic biomarker of human colorectal cancer

H. Kwon, Junghwa Chang, Hyun-chul Kim, 2017, Experimental & Molecular Medicine.

MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer

H. Kwon, Wankyu Kim, Jong-Won Oh, 2020, Scientific Reports.

Terpestacin Inhibits Tumor Angiogenesis by Targeting UQCRB of Mitochondrial Complex III and Suppressing Hypoxia-induced Reactive Oxygen Species Production and Cellular Oxygen Sensing*

H. Kwon, J. Shim, Jiyong Lee, 2010, The Journal of Biological Chemistry.

Daptomycin suppresses tumor migration and angiogenesis via binding to ribosomal protein S19 in humans

Hwa Jung Lee, H. Kwon, P. Karuso, 2021, The Journal of antibiotics.

The effect of indatraline on angiogenesis suppression through HIF-1α-mediated VEGF inhibition.

H. Kwon, Yoon Sun Cho, Chih-na Yen, 2017, Biochemical and biophysical research communications.

Identification of a Novel Sulfonamide Non-Nucleoside Reverse Transcriptase Inhibitor by a Phenotypic HIV-1 Full Replication Assay

Sung-Jun Han, Peter Sommer, Ho Jeong Kwon, 2013, PloS one.

Identification and validation of bioactive small molecule target through phenotypic screening.

H. Kwon, Yoon Sun Cho, 2012, Bioorganic & medicinal chemistry.

The novel histone deacetylase inhibitor, N-hydroxy-7-(2-naphthylthio) hepatonomide, exhibits potent antitumor activity due to cytochrome-c-release-mediated apoptosis in renal cell carcinoma cells

H. Kwon, K. Park, S. Hong, 2015, BMC Cancer.

Molecular mechanism of ADP-ribosyl cyclase activation in angiotensin II signaling in murine mesangial cells.

H. Kwon, S. K. Park, Suhn Hee Kim, 2008, American journal of physiology. Renal physiology.

Autophagonizer, a novel synthetic small molecule, induces autophagic cell death.

H. Kwon, Yoon Sun Cho, H. Jung, 2010, Biochemical and biophysical research communications.

A new histone deacetylase inhibitor improves liverfibrosis in BDL rats through suppression of hepatic stellate cells

H. Kwon, K. Park, Seung-hoon Choi, 2014, British journal of pharmacology.

Plakoglobin is a new target gene of histone deacetylase in human fibrosarcoma HT1080 cells

Dong Hoon Kim, H. Kwon, J. Shim, 2004, Oncogene.

Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth.

Jun O. Liu, H. Kwon, W. Ge, 2017, Cancer letters.

Identification of a resveratrol tetramer as a potent inhibitor of hepatitis C virus helicase

H. Kwon, Hongje Jang, Dal‐Hee Min, 2015, British journal of pharmacology.

Purification and Properties ofd-Xylose Isomerase from AlkalophilicBacillusNo. KX-6

H. Kwon, K. Horikoshi, M. Kitada, 1987 .

Wondonins A and B, new bis(dihydroxystyryl)imidazoles from a two-sponge association

H. Kwon, J. Rho, Hyi-Seung Lee, 2001 .

Potent inhibition of in vivo angiogenesis and tumor growth by a novel cyclooxygenase‐2 inhibitor, enoic acanthoic acid

H. Kwon, M. Ono, J. Shim, 2007, Cancer science.

Identification and validation of calmodulin as a binding protein of an anti‐proliferative small molecule 3,4‐dihydroisoquinolinium salt

H. Kwon, J. Shim, Jungchan Park, 2009, Proteomics. Clinical applications.

A novel autophagy enhancer as a therapeutic agent against metabolic syndrome and diabetes

H. Kwon, Myung-Shik Lee, Hui-Yun Hwang, 2018, Nature Communications.

Focal Adhesion Kinase Regulates Syndecan-2 – Mediated Tumorigenic Activity of HT 1080 Fibrosarcoma Cells

H. Kwon, E. Oh, Haein Park, 2005 .

Endogenous expression mapping of malignant melanoma by mass spectrometry imaging

H. Olsson, H. Kwon, C. Ingvar, 2018, Clinical and Translational Medicine.

Suppression of morphological transformation by radicicol is accompanied by enhanced gelsolin expression

H. Kwon, S. Horinouchi, T. Obinata, 1997, Oncogene.

Homoisoflavanone inhibits retinal neovascularization through cell cycle arrest with decrease of cdc2 expression.

H. Kwon, Jin Hyoung Kim, Y. Yu, 2007, Biochemical and biophysical research communications.

Inhibitory activity of diacylglycerol acyltransferase by cochlioquinones A and A1.

Young Kook Kim, H. Kwon, C. Lim, 2003, Journal of antibiotics (Tokyo. 1968).

Cochlioquinone A1, a New anti‐Angiogenic Agent from Bipolaris zeicola.

H. Kwon, H. Lee, H. Jung, 2004 .

Inhibition of NFkappaB by methyl chlorogenate from Eriobotrya japonica.

H. Kwon, H. Chung, K. Paik, 2000, Molecules and cells.

Spatially Resolved Proteomic and Transcriptomic Profiling of Anaplastic Lymphoma Kinase-Rearranged Pulmonary Adenocarcinomas Reveals Key Players in Inter- and Intratumoral Heterogeneity

H. Kwon, T. Glasz, J. Moldvay, 2023, International journal of molecular sciences.

A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase.

H. Kwon, Qing Liu, Ming-Wei Wang, 2018, ACS chemical biology.

N-hydroxy-7-(2-naphthylthio) heptanomide inhibits retinal and choroidal angiogenesis.

H. Kwon, Jin Hyoung Kim, Kyu-Won Kim, 2009, Molecular pharmaceutics.

Confocal-Based Method for Quantification of Diffusion Kinetics in Microwell Plates and Its Application for Identifying a Rapid Mixing Method for High-Content/Throughput Screening

H. Kwon, J. Cechetto, T. Christophe, 2010, Journal of biomolecular screening.

NBBA, a synthetic small molecule, inhibits TNF-alpha-induced angiogenesis by suppressing the NF-kappaB signaling pathway.

F. Shibasaki, H. Kwon, N. Kim, 2010, Biochemical and biophysical research communications.

Anti-Angiogenic Activity of Acalycixenolide E, a Novel Marine Natural Product from Acallycigorgia inermis

H. Kwon, Jin Hee Kim, J. Rho, 2001 .

The Small Molecule R-(-)-β-O-Methylsynephrine Binds to Nucleoporin 153 kDa and Inhibits Angiogenesis

H. Kwon, J. Shim, J. H. Kim, 2015, International journal of biological sciences.

Synthesis and biological activity of fungal metabolite, 4-hydroxy-3-(3'-methyl-2'-butenyl)-benzoic acid.

H. Kwon, Jin Hye Kim, 2007, Journal of Microbiology and Biotechnology.

MiR-4435 is an UQCRB-related circulating miRNA in human colorectal cancer

H. Kwon, Wankyu Kim, Jong-Won Oh, 2020, Scientific Reports.

Inhibition of choroidal neovascularization by homoisoflavanone, a new angiogenesis inhibitor

H. Kwon, Jin Hyoung Kim, Kyu-Won Kim, 2008, Molecular vision.

Trichostatin A attenuates airway inflammation in mouse asthma model

H. Kwon, G. Oh, S. Oh, 2005, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Hsa-miR-10a-5p downregulation in mutant UQCRB-expressing cells promotes the cholesterol biosynthesis pathway

H. Kwon, Wankyu Kim, Jisun Lim, 2018, Scientific Reports.

Antiangiogenic activity of herboxidiene via downregulation of vascular endothelial growth factor receptor-2 and hypoxia-inducible factor-1α

H. Kwon, J. Sohng, H. Jung, 2015, Archives of pharmacal research.

Depudecin induces morphological reversion of transformed fibroblasts via the inhibition of histone deacetylase.

S. Schreiber, T. Owa, H. Kwon, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Antiangiogenic Activity of the Lipophilic Antimicrobial Peptides from an Endophytic Bacterial Strain Isolated from Red Pepper Leaf

H. Kwon, H. Lee, H. Jung, 2014, Molecules and cells.

Approaches for discovering novel bioactive small molecules targeting autophagy

H. Kwon, Hui-Yun Hwang, S. Cho, 2017, Expert opinion on drug discovery.

Exploring the role of mitochondrial UQCRB in angiogenesis using small molecules.

H. Kwon, H. Jung, 2013, Molecular Biosystems.

A histone demethylase inhibitor, methylstat, inhibits angiogenesis in vitro and in vivo

H. Kwon, Yoon Sun Cho, Xiang Wang, 2014 .

Mitochondrial UQCRB regulates VEGFR2 signaling in endothelial cells

H. Kwon, S. Kang, J. H. Kim, 2013, Journal of Molecular Medicine.

ER translocon inhibitor ipomoeassin F inhibits triple-negative breast cancer growth via blocking ER molecular chaperones

H. Kwon, J. Shim, Jianhong Zhou, 2023, International journal of biological sciences.

Novel functional proteins coded by the human genome discovered in metastases of melanoma patients

H. Olsson, H. Kwon, C. Ingvar, 2019, Cell Biology and Toxicology.

Inhibitory activity of diacylglycerol acyltransferase by cochlioquinones A and A1.

Young Kook Kim, H. Kwon, C. Lim, 2003, The Journal of antibiotics.

N-hydroxy-7-(2-naphthylthio) heptanomide inhibits retinal and choroidal angiogenesis.

H. Kwon, Jin Hyoung Kim, Kyu-Won Kim, 2009, Molecular Pharmaceutics.

Moesin is a biomarker for the assessment of genotoxic carcinogens in mouse lymphoma

H. Kwon, Sue-N. Park, Y. Sheen, 2012, Molecules and Cells.

Antiangiogenic activity of herboxidiene via downregulation of vascular endothelial growth factor receptor-2 and hypoxia-inducible factor-1α

H. Kwon, J. Sohng, H. Jung, 2015, Archives of pharmacal research.

Anti-Obesity Phenotypic Screening Looking to Increase OBR Cell Surface Expression

H. Kwon, Dong-Hwa Choi, R. Jockers, 2014, Journal of biomolecular screening.

Chemical genomics with natural products

H. Kwon, H. Jung, 2006 .