M. Walter

发表

A method for constructing radiation hybrid maps of whole genomes

J. Weissenbach, P. Goodfellow, D. Spillett, 1994, Nature Genetics.

FOXC1 is a potential prognostic biomarker with functional significance in basal-like breast cancer.

A. Giuliano, J. Martens, A. Richardson, 2010, Cancer research.

Regulation of FOXC1 Stability and Transcriptional Activity by an Epidermal Growth Factor-activated Mitogen-activated Protein Kinase Signaling Cascade*

M. Walter, F. Berry, F. Mirzayans, 2006, Journal of Biological Chemistry.

Accurate prediction of functional, structural, and stability changes in PITX2 mutations using in silico bioinformatics algorithms

Morteza Seifi, M. Walter, M. Seifi, 2018, PloS one.

Ocular genetics in the genomics age

M. Walter, G. Arno, T. Rezaie, 2020, American journal of medical genetics. Part C, Seminars in medical genetics.

Phenotypic heterogeneity of CYP1B1: mutations in a patient with Peters' anomaly

M. Walter, E. Héon, J. Sutherland, 2001, Journal of medical genetics.

Functional analyses of two newly identified PITX2 mutants reveal a novel molecular mechanism for Axenfeld-Rieger syndrome.

M. Walter, Y. Buys, E. Héon, 2001, Human molecular genetics.

Ocular developmental abnormalities and glaucoma associated with interstitial 6p25 duplications and deletions.

R. Ekong, A. Mungall, S. Povey, 2002, Investigative ophthalmology & visual science.

PITs and FOXes in ocular genetics: the Cogan lecture.

M. Walter, 2003, Investigative ophthalmology & visual science.

The interactions of genes, age, and environment in glaucoma pathogenesis.

M. Walter, Lance P Doucette, M. Seifi, 2015, Survey of ophthalmology.

Novel PITX2 gene mutations in patients with Axenfeld‐Rieger syndrome

M. Walter, Sherryl A. M. Taylor, E. Abdalla, 2016, Acta ophthalmologica.

Comparison of Bioinformatics Prediction, Molecular Modeling, and Functional Analyses of FOXC1 Mutations in Patients with Axenfeld‐Rieger Syndrome

M. Walter, Sherryl A. M. Taylor, M. Seifi, 2017, Human mutation.

Dysfunction of the stress-responsive FOXC1 transcription factor contributes to the earlier-onset glaucoma observed in Axenfeld-Rieger syndrome patients

M. Walter, F. Berry, I. Goping, 2014, Cell Death and Disease.

A Novel PITX2c Gain-of-Function Mutation, p.Met207Val, in Patients With Familial Atrial Fibrillation.

M. Walter, Yi-Qing Yang, A. Aranega, 2019, The American journal of cardiology.

FGF19 is a target for FOXC1 regulation in ciliary body-derived cells.

M. Walter, F. Berry, Y. Tamimi, 2006, Human molecular genetics.

The immunoglobulin heavy chain and disease association: application to pemphigus vulgaris

M. Walter, D. Cox, A. Ahmed, 1994, Human Genetics.

Cloning, characterization, localization, and mutational screening of the human BARX1 gene.

M. Walter, D. B. Gould, D. Gould, 2000, Genomics.

Isolation of a novel iris-specific and leucine-rich repeat protein (oculoglycan) using differential selection.

M. Walter, J. Friedman, V. Raymond, 2000, Investigative ophthalmology & visual science.

Physical MappingofFourSerpin Genes:a,-Antitrypsin,

M. Walter, G. Billingsley, G. Hammond, 1993 .

A method for two-dimensional DNA electrophoresis (2D-DE): application to the immunoglobulin heavy chain variable region.

M. Walter, D. Cox, 1989, Genomics.

Variation in residual PITX2 activity underlies the phenotypic spectrum of anterior segment developmental disorders.

M. Walter, K. Kozlowski, 2000, Human molecular genetics.

Role of PRKC Apoptosis WT1 Regulator in Ocular Development and Diseases

M. Walter, Tahseen Ahmed, Moulinath Acharya, 2021, Tumor Suppressor Par-4.

Physical mapping of four serpin genes: alpha 1-antitrypsin, alpha 1-antichymotrypsin, corticosteroid-binding globulin, and protein C inhibitor, within a 280-kb region on chromosome I4q32.1.

M. Walter, D. Cox, G. Billingsley, 1993, American journal of human genetics.

Chromosomal localization and genomic organization of the human retinal rod Na-Ca+K exchanger

D. Demetrick, M. Walter, J. Friedman, 1998, Human Genetics.

Axenfeld-Rieger syndrome resulting from mutation of the FKHL7 gene on chromosome 6p25

M. Walter, F. Mirzayans, E. Héon, 2000, European Journal of Human Genetics.

Disease and development

P. Goodfellow, M. Walter, 1992, Nature.

Opticin binds retinal growth hormone in the embryonic vitreous.

M. Walter, E. Sanders, S. Harvey, 2003, Investigative ophthalmology & visual science.

A complex regulatory network of transcription factors critical for ocular development and disease.

M. Walter, Lijia Huang, W. Allison, 2011, Human molecular genetics.

A variant in a cis‐regulatory element enhances claudin‐14 expression and is associated with pediatric‐onset hypercalciuria and kidney stones

M. Walter, Mathieu Lemaire, J. Herrmann, 2017, Human mutation.

Autosomal-dominant iridogoniodysgenesis and Axenfeld-Rieger syndrome are genetically distinct.

M. Walter, F. Mirzayans, W. Pearce, 1996, Ophthalmology.

Mutation of the PAX6 gene in patients with autosomal dominant keratitis.

M. Walter, I. MacDonald, F. Mirzayans, 1995, American journal of human genetics.

Mutations of conserved non-coding elements of PITX2 in patients with ocular dysgenesis and developmental glaucoma

Meredith E. Protas, R. Ritch, M. Walter, 2017, Human molecular genetics.

Genetic study of SOX9 in a case of campomelic dysplasia.

M. Walter, J. S. Bamforth, J. Giordano, 2001, American journal of medical genetics.

Roles for the winged helix transcription factors MF1 and MFH1 in cardiovascular development revealed by nonallelic noncomplementation of null alleles.

B. Hogan, M. Walter, T. Kume, 1999, Developmental biology.

Two-Dimensional DNA Electrophoresis (2D-DE) for Mammalian DNA.

M. Walter, D. Cox, 1992, Methods in molecular biology.

A multigene deletion in the immunoglobulin heavy chain region in a highly atopic individual

M. Walter, D. Cox, B. Zimmerman, 1990, Human Genetics.

Yeast two-hybrid analysis of a human trabecular meshwork cDNA library identified EFEMP2 as a novel PITX2 interacting protein

M. Walter, Lijia Huang, F. Mirzayans, 2012, Molecular vision.

Analysis of mutations of the PITX2 transcription factor found in patients with Axenfeld-Rieger syndrome.

M. Walter, K. Kozlowski, F. Idrees, 2009, Investigative ophthalmology & visual science.

Human PRKC Apoptosis WT1 Regulator Is a Novel PITX2-interacting Protein That Regulates PITX2 Transcriptional Activity in Ocular Cells*

M. Walter, Lijia Huang, P. Gage, 2009, The Journal of Biological Chemistry.

Functional interactions between FOXC1 and PITX2 underlie the sensitivity to FOXC1 gene dose in Axenfeld-Rieger syndrome and anterior segment dysgenesis.

M. Walter, F. Berry, D. Underhill, 2006, Human molecular genetics.

Physical Mapping of Four Serpin Genes : a ,-Antitrypsin , a ,-Antichymotrypsin , Corticosteroid-binding Globulin , and Protein C Inhibitor , within a 280-kb Region on Chromosome 1 4 q 32 . 1

M. Walter, D. Cox, G. Billingsley, 2006 .

Mutation of the bone morphogenetic protein GDF3 causes ocular and skeletal anomalies.

M. Walter, O. Lehmann, A. Waskiewicz, 2010, Human molecular genetics.

Identification of target genes regulated by FOXC1 using nickel agarose-based chromatin enrichment.

M. Walter, Y. Tamimi, M. Lines, 2004, Investigative ophthalmology & visual science.

Further support of the role of CYP1B1 in patients with Peters anomaly.

M. Walter, E. Héon, E. Oliver, 2006, Molecular vision.

Genomics and anterior segment dysgenesis: a review

M. Walter, Y. A. Ito, 2014, Clinical & experimental ophthalmology.

Aniridia and Axenfeld-Rieger Syndrome: Clinical presentations, molecular genetics and current/emerging therapies.

M. Walter, Paul W Chrystal, 2019, Experimental eye research.

Severe molecular defects of a novel FOXC1 W152G mutation result in aniridia.

Yoko Ito, M. Walter, F. Berry, 2009, Investigative ophthalmology & visual science.

Molecular Genetics of Pigment Dispersion Syndrome and Pigmentary Glaucoma: New Insights into Mechanisms

M. Walter, Adrian A Lahola-Chomiak, 2018, Journal of ophthalmology.

Characterization and prevalence of PITX2 microdeletions and mutations in Axenfeld-Rieger malformations.

M. Walter, E. Héon, M. B. Shields, 2004, Investigative ophthalmology & visual science.

Molecular genetics of Axenfeld-Rieger malformations.

M. Walter, M. Lines, K. Kozlowski, 2002, Human molecular genetics.

Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly.

J. Morissette, W. Kuo, R. Ritch, 1998, American journal of human genetics.

Autosomal dominant iridogoniodysgenesis anomaly maps to 6p25.

M. Walter, F. Mirzayans, W. Pearce, 1996, American journal of human genetics.

A High-Resolution Radiation Hybrid Map of the Region Surrounding the Gorlin Syndrome Gene

P. Goodfellow, H. Jones, M. Walter, 1996, European journal of human genetics : EJHG.

Genetics and Environmental Stress Factor Contributions to Anterior Segment Malformations and Glaucoma

Yoko Ito, M. Walter, 2013 .

FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A.

T. Hudson, M. Walter, F. Berry, 2007, Human molecular genetics.

Letters to the Editor SHOX point mutations in dyschondrosteosis

M. Walter, T. Glaser, J. Sutherland, 2001 .

Prostaglandins in the eye: Function, expression, and roles in glaucoma

M. Walter, Lance P Doucette, 2017, Ophthalmic genetics.

Physical linkage of a human immunoglobulin heavy chain variable region gene segment to diversity and joining region elements.

M. Walter, A. Ebens, E. Milner, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Protein localization in the human eye and genetic screen of opticin.

M. Walter, V. Biron, J. Friedman, 2002, Human molecular genetics.

Nonuniform linkage disequilibrium within a 1,500-kb region of the human immunoglobulin heavy-chain complex.

M. Walter, D. Cox, 1991, American journal of human genetics.

FOXQ1 is Differentially Expressed Across Breast Cancer Subtypes with Low Expression Associated with Poor Overall Survival

Paulo A. S. Nuin, M. Walter, Sunita Ghosh, 2021, Breast cancer.

BCTT_A_282860 171..188

Paulo A. S. Nuin, M. Walter, Sunita Ghosh, 2021 .

Immunoglobulin heavy chain variable region polymorphisms and multiple sclerosis susceptibility

M. Walter, G. Ebers, D. Cox, 1993, Journal of Neuroimmunology.

Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region.

M. Walter, G. Ebers, D. Cox, 1991, The Journal of clinical investigation.

Absence of NR2E1 mutations in patients with aniridia

E. Simpson, A. Brooks-Wilson, M. Walter, 2012, Molecular vision.

A novel mechanistic spectrum underlies glaucoma-associated chromosome 6p25 copy number variation.

N. Carter, A. Mungall, M. Walter, 2008, Human molecular genetics.

Functional Domains and Evolutionary History of the PMEL and GPNMB Family Proteins

M. Walter, W. T. Allison, Paul W Chrystal, 2021, Molecules.

SOX Genes: Architects of Development

M. Walter, H. Prior, 1996, Molecular medicine.

Irradiation and fusion gene transfer

P. Goodfellow, M. Walter, 1995, Molecular biotechnology.

FOXC1, the new player in the cancer sandbox

M. Walter, E. Yan, Fahed A. Elian, 2015, Oncotarget.

The establishment of a predictive mutational model of the forkhead domain through the analyses of FOXC2 missense mutations identified in patients with hereditary lymphedema with distichiasis.

M. Walter, O. Lehmann, F. Berry, 2005, Human molecular genetics.

FOXC1 Transcriptional Regulation Is Mediated by N- and C-terminal Activation Domains and Contains a Phosphorylated Transcriptional Inhibitory Domain*

M. Walter, R. Saleem, F. Berry, 2002, The Journal of Biological Chemistry.

SHOX point mutations in dyschondrosteosis

M. Walter, E. Héon, J. Sutherland, 2001 .

FOXA1 deletion in luminal epithelium causes prostatic hyperplasia and alteration of differentiated phenotype

K. Kaestner, R. Matusik, S. Hayward, 2014, Laboratory Investigation.

Localization and genetic linkage of the human immunoglobulin heavy chain genes and the creatine kinase brain (CKB) gene: identification of a hot spot for recombination.

M. Walter, D. Cox, G. Daouk, 1991, Genomics.

Priority Report Cancer Research FOXC 1 Is a Potential Prognostic Biomarker with Functional Significance in Basal-like Breast Cancer

A. Giuliano, J. Martens, A. Richardson, 2010 .

Chromosomal anomalies on 6p25 in iris hypoplasia and Axenfeld‐Rieger syndrome patients defined on a purpose‐built genomic microarray

R. Ekong, S. Povey, T. Gant, 2004, Human mutation.

FOXF2 is required for cochlear development in humans and mice.

M. Tekin, M. Walter, S. Blanton, 2018, Human molecular genetics.

Human p32 is a novel FOXC1-interacting protein that regulates FOXC1 transcriptional activity in ocular cells.

M. Walter, Lijia Huang, F. Berry, 2008, Investigative ophthalmology & visual science.

Genotype-phenotype correlations in Axenfeld-Rieger malformation and glaucoma patients with FOXC1 and PITX2 mutations.

M. Walter, I. Dinu, M. Strungaru, 2006, Investigative ophthalmology & visual science.

Analyses of a novel L130F missense mutation in FOXC1.

Yoko Ito, M. Walter, W. Courtens, 2007, Archives of ophthalmology.

FOXC1 Transcriptional Regulatory Activity Is Impaired by PBX1 in a Filamin A-Mediated Manner

M. Walter, F. Berry, M. A. O’Neill, 2005, Molecular and Cellular Biology.

The wing 2 region of the FOXC1 forkhead domain is necessary for normal DNA-binding and transactivation functions.

M. Walter, R. Saleem, B. McGillivray, 2004, Investigative ophthalmology & visual science.

Phenotypic and molecular assessment of seven patients with 6p25 deletion syndrome: Relevance to ocular dysgenesis and hearing impairment

R. Ritch, M. Walter, I. MacDonald, 2004, BMC Medical Genetics.

Essential structural and functional determinants within the forkhead domain of FOXC1.

M. Walter, A. Baxevanis, R. Saleem, 2004, Nucleic acids research.

Structural and functional analyses of disease-causing missense mutations in the forkhead domain of FOXC1.

M. Walter, A. Baxevanis, R. Saleem, 2003, Human molecular genetics.

Identification and analysis of a novel mutation in the FOXC1 forkhead domain.

M. Walter, R. Saleem, J. Liebmann, 2003, Investigative ophthalmology & visual science.

Structural and functional analyses of disease-causing missense mutations in the forkhead domain of FOXC 1

M. Walter, A. Baxevanis, R. Saleem, 2003 .

Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1.

M. Walter, A. Baxevanis, R. Saleem, 2001, American journal of human genetics.

The Forkhead/Winged Helix Gene Mf1 Is Disrupted in the Pleiotropic Mouse Mutation congenital hydrocephalus

B. Hogan, M. Walter, T. Kume, 1998, Cell.

Mutation in the RIEG1 gene in patients with iridogoniodysgenesis syndrome.

M. Walter, E. Semina, W. Pearce, 1998, Human molecular genetics.

Radiation hybrids: irradiation and fusion gene transfer.

P. Goodfellow, M. Walter, 1993, Trends in genetics : TIG.

FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25

M. Walter, V. Raymond, Lance P Doucette, 2017, PloS one.

PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3.

M. Walter, F. Berry, V. Raymond, 2011, Investigative ophthalmology & visual science.

FOXC2 disease-mutations identified in lymphedema-distichiasis patients cause both loss and gain of protein function

M. Walter, D. Tavian, S. Missaglia, 2016, Oncotarget.

Co-variation of STI1 and WDR36/UTP21 alters cell proliferation in a glaucoma model

M. Walter, M. Sarfarazi, S. Dubois, 2011, Molecular vision.

Glaucoma-associated WDR36 variants encode functional defects in a yeast model system.

M. Walter, S. Dubois, V. Raymond, 2009, Human molecular genetics.

Complete physical map of the human immunoglobulin heavy chain constant region gene complex.

M. Walter, D. Cox, M. Hofker, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of genetic variation reveals human immunoglobulin VH-region gene organization.

M. Walter, D. Cox, 1988, American journal of human genetics.

A deletion map of the human immunoglobulin heavy chain variable region

M. Walter, D. Cox, H. Dosch, 1991, The Journal of experimental medicine.

Isolation of a ubiquitin-like (UBL5) gene from a screen identifying highly expressed and conserved iris genes.

M. Walter, J. Friedman, B. Koop, 2001, Genomics.

Identification of the human chromosomal region containing the iridogoniodysgenesis anomaly locus by genomic-mismatch scanning.

M. Walter, F. Mirzayans, W. Pearce, 1997, American journal of human genetics.

Ig H chain variable and C region genes in common variable immunodeficiency. Characterization of two new deletion haplotypes.

M. Walter, L. Hammarström, D. Cox, 1991, Journal of immunology.

Non-Synonymous variants in premelanosome protein (PMEL) cause ocular pigment dispersion and pigmentary glaucoma.

L. Pasquale, R. Ritch, M. Walter, 2018, Human molecular genetics.

Genomic mismatch scanning for the mapping of genetic traits.

M. Walter, F. Mirzayans, F Mirzayans, 2001, Methods in molecular biology.

DEVELOPMENT AL AND CELLULAR BIOLOGY OF COELENTERATES

Todd A Schmidt, A. Gierer, J. Lepault, 2010 .

Mutational analysis of BARHL1 and BARX1 in three new patients with Joubert syndrome

M. Walter, D. Gould, 2004, American journal of medical genetics. Part A.

Identification and analysis of evolutionary selection pressures acting at the molecular level in five forkhead subfamilies

B. Rannala, M. Walter, C. Fetterman, 2008, BMC Evolutionary Biology.

Introduction to the special issue on Ophthalmic Genetics: Vision in 2020

M. Walter, G. Arno, R. Hufnagel, 2020, American journal of medical genetics. Part C, Seminars in medical genetics.

FOXC1 Regulates Expression of Prostaglandin Receptors Leading to an Attenuated Response to Latanoprost.

M. Walter, Lance P Doucette, T. Footz, 2018, Investigative ophthalmology & visual science.

A high-resolution whole genome radiation hybrid map of human chromosome 17q22-q25.3 across the genes for GH and TK.

J. W. Foster, P. Goodfellow, D. Spillett, 1996, Genomics.

A novel mechanistic spectrum underlies glaucoma-associated chromosome 6p25 copy number variation.

N. Carter, A. Mungall, M. Walter, 2008, Human molecular genetics.

Prostaglandins in the eye: Function, expression, and roles in glaucoma

M. Walter, Lance P. Doucette, 2017, Ophthalmic genetics.

Absence of PITX2, BARX1, and FOXC1 mutations in De Hauwere syndrome (Axenfeld–Rieger anomaly, hydrocephaly, hearing loss): A 25‐year follow up

M. Walter, R. Lowry, D. Gould, 2007, American journal of medical genetics. Part A.

A deletion map of the human immunoglobulin heavy chain variable region

M. Walter, D. Cox, H. Dosch, 1991, The Journal of experimental medicine.