T. Rush

发表

A shape-based 3-D scaffold hopping method and its application to a bacterial protein-protein interaction.

J. A. Grant, T. Rush, L. Mosyak, 2005, Journal of medicinal chemistry.

Rethinking drug design in the artificial intelligence era

G. Schneider, J. Listgarten, A. Plowright, 2019, Nature Reviews Drug Discovery.

Molecular mechanism of action of pharmacoperone rescue of misrouted GPCR mutants: the GnRH receptor.

T. Rush, M. Altman, A. Cornea, 2009, Molecular endocrinology.

Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design.

Ramaswamy Nilakantan, Russell G Dushin, Désirée H H Tsao, 2006, Bioorganic & medicinal chemistry.

Efficient identification of novel leads by dynamic focused screening: PDK1 case stud.

Dongyu Sun, Ekaterina Bobkova, I. Kariv, 2010, Combinatorial chemistry & high throughput screening.

Functional, Biophysical, and Structural Bases for Antibacterial Activity of Tigecycline

T. Rush, J. O'Connell, E. Feyfant, 2006, Antimicrobial Agents and Chemotherapy.

Design and synthesis of indolo[2,3-a]quinolizin-7-one inhibitors of the ZipA-FtsZ interaction.

T. Rush, L. Mosyak, Yuanhong Li, 2004, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors.

T. Rush, J. Xiang, S. Tam, 2006, Bioorganic & medicinal chemistry letters.

3,4-Disubstituted benzofuran P1' MMP-13 inhibitors: optimization of selectivity and reduction of protein binding.

T. Rush, J. Skotnicki, J. Levin, 2009, Bioorganic & medicinal chemistry letters.

Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA-FtsZ interaction.

T. Rush, L. Mosyak, S. Haney, 2004, Bioorganic & medicinal chemistry.

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis.

T. Rush, J. Skotnicki, J. Levin, 2005, Bioorganic & medicinal chemistry.

Synthesis and SAR of highly selective MMP-13 inhibitors.

T. Rush, J. Skotnicki, J. Levin, 2005, Bioorganic & medicinal chemistry letters.

Ab Initio Transform Calculation of Resonance Raman Spectra of Uracil, 1-Methyluracil, and 5-Methyluracil

T. Rush, W. Peticolas, 1995 .

Room-temperature gas chromatography/mass spectrometry of volatile solids and of volatiles trapped in solids

W. Jackson, T. Rush, A. Collier, 1983 .

IR spectra of cytochrome c denatured with deuterated guanidine hydrochloride show increase in beta sheet.

T. Rush, J. O. Speare, Thomas S Rush, 2003, Biopolymers.

Simulation of Non-Condon Enhancement and Interference Effects in the Resonance Raman Intensities of Metalloporphyrins

T. Rush, T. Spiro, P. Kozlowski, 1998 .

Modeling the Soret-Resonant Raman Intensities of Metalloporphyrins and Heme Proteins. 1. Nickel Porphine

T. Rush, T. Spiro, Arka Mukherjee, 1996 .

Development of High-Throughput TR-FRET and AlphaScreen® Assays for Identification of Potent Inhibitors of PDK1

I. Kariv, T. Rush, J. Andersen, 2009, Journal of biomolecular screening.

The discovery of tricyclic pyridone JAK2 inhibitors. Part 1: hit to lead.

T. Rush, M. Altman, Joon Jung, 2010, Bioorganic & medicinal chemistry letters.

Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms.

Thomas Rush, Andrew M Haidle, Michael D Altman, 2014, Bioorganic & medicinal chemistry letters.

Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors.

W. R. Bishop, R. Sullivan, K. Flaherty, 2018, JCI insight.

FeNO structure in distal pocket mutants of myoglobin based on resonance Raman spectroscopy.

T. Rush, M. Ikeda-Saito, J. Olson, 2003, Biochemistry.

A parallel algorithm for calculating the potential energy in DNA

John S. Conery, Warner L. Peticolas, Kesavan Shanmugam, 1995, Proceedings of the Twenty-Eighth Annual Hawaii International Conference on System Sciences.

Identification of potent and selective MMP-13 inhibitors.

T. Rush, E. Collins, J. Levin, 2005, Bioorganic & medicinal chemistry letters.

The application of x-ray, NMR, and molecular modeling in the design of MMP inhibitors.

R. Powers, T. Rush, 2004, Current topics in medicinal chemistry.

Structure-based design of carboxybiphenylindole inhibitors of the ZipA-FtsZ interaction.

J. Alvarez, T. Rush, L. Mosyak, 2003, Organic & biomolecular chemistry.

Alternative modes of substrate distortion in enzyme and antibody catalyzed ferrochelation reactions.

P. Schultz, T. Rush, F. Romesberg, 1998, Biochemistry.

The Role of Helix 1 Aspartates and Salt Bridges in the Stability and Conversion of Prion Protein*

B. Caughey, T. Rush, M. Bloom, 2003, The Journal of Biological Chemistry.

Structure-based identification of the binding site for the hemiasterlin analogue HTI-286 on tubulin.

T. Rush, M. Ravi, A. Zask, 2005, Biochemistry.

Impact of mobility on structure-based drug design for the MMPs.

R. Powers, T. Rush, P. Chanda, 2002, Journal of the American Chemical Society.

Identification of potent and selective MMP-13 inhibitors.

T. Rush, E. Collins, J. Levin, 2005, Bioorganic & medicinal chemistry letters.

Ab initio calculations of the ultraviolet resonance Raman spectra of uracil

Warner L. Peticolas, Thomas Rush, T. Rush, 1995, J. Comput. Chem..