I. Lu

发表

Structure-based drug design of a novel family of PPARgamma partial agonists: virtual screening, X-ray crystallography, and in vitro/in vivo biological activities.

I. Lu, Chien-Fu Huang, Yi-Hui Peng, 2006, Journal of medicinal chemistry.

A three-dimensional pharmacophore model for dipeptidyl peptidase IV inhibitors.

I. Lu, N. Mahindroo, Xin Chen, 2008, European journal of medicinal chemistry.

Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease.

Po-Huang Liang, I-Lin Lu, Chih-Jung Kuo, 2006, Journal of medicinal chemistry.

Glutamic acid analogues as potent dipeptidyl peptidase IV and 8 inhibitors.

I. Lu, Xin Chen, Su-Ying Wu, 2005, Bioorganic & medicinal chemistry letters.

Discovery of a novel family of SARS-CoV protease inhibitors by virtual screening and 3D-QSAR studies.

Thy-Hou Lin, Po-Huang Liang, I-Lin Lu, 2006, Journal of medicinal chemistry.

Structure-Based Inhibitors Exhibit Differential Activities against Helicobacter pylori and Escherichia coli Undecaprenyl Pyrophosphate Synthases

Po-Huang Liang, I-Lin Lu, Chih-Jung Kuo, 2008, Journal of biomedicine & biotechnology.

Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: design, synthesis, structural biology, and molecular docking studies.

Ping-Chiang Lyu, I-Lin Lu, Ying-Ting Lin, 2006, Journal of medicinal chemistry.

Novel indole-based peroxisome proliferator-activated receptor agonists: design, SAR, structural biology, and biological activities.

I-Lin Lu, Chien-Fu Huang, Yu-Sheng Chao, 2005, Journal of medicinal chemistry.

Structural basis for the structure-activity relationships of peroxisome proliferator-activated receptor agonists.

Ping-Chiang Lyu, I-Lin Lu, Yu-Sheng Chao, 2007, Journal of medicinal chemistry.

Protein-specific Scoring Method for Ligand Discovery

Hsiuying Wang, I-Lin Lu, I. Lu, 2012, J. Comput. Biol..

2-[3-[2-[(2S)-2-Cyano-1-pyrrolidinyl]-2-oxoethylamino]-3-methyl-1-oxobutyl]- 1,2,3,4-tetrahydroisoquinoline: a potent, selective, and orally bioavailable dipeptide-derived inhibitor of dipeptidyl peptidase IV.

I. Lu, H. Hsieh, C. Chen, 2006, Journal of medicinal chemistry.