Shigehiro Asano

发表

Identification of phosphodiesterase-1 and 5 dual inhibitors by a ligand-based virtual screening optimized for lead evolution.

Kazuto Yamazaki, N. Kusunose, K. Fujita, 2006, Bioorganic & medicinal chemistry letters.

Intellectual Property in the Field of Regenerative Medicine in Japan.

Shigehiro Asano, Y. Nakanishi, D. Sugiyama, 2018, Clinical therapeutics.

Improving the Serum Stability of Site-Specific Antibody Conjugates with Sulfone Linkers

C. Barbas, Shigehiro Asano, Xiuling Li, 2014, Bioconjugate chemistry.

A novel class of antihyperlipidemic agents with low density lipoprotein receptor up-regulation via the adaptor protein autosomal recessive hypercholesterolemia.

Shigehiro Asano, Hitoshi Ban, K. Kino, 2010, Journal of medicinal chemistry.

Rapid, stable, chemoselective labeling of thiols with Julia-Kocieński-like reagents: a serum-stable alternative to maleimide-based protein conjugation.

C. Barbas, Shigehiro Asano, N. Toda, 2013, Angewandte Chemie.

Site-selective labeling of a lysine residue in human serum albumin.

C. Barbas, Shigehiro Asano, T. Gaj, 2014, Angewandte Chemie.

Synthesis and structure based optimization of 2-(4-phenoxybenzoyl)-5-hydroxyindole as a novel CaMKII inhibitor.

Shigehiro Asano, N. Koike, J. Igarashi, 2012, Bioorganic & medicinal chemistry.

Structure and activity relationship of 2-(substituted benzoyl)-hydroxyindoles as novel CaMKII inhibitors.

Shigehiro Asano, N. Koike, J. Igarashi, 2011, Bioorganic & medicinal chemistry letters.

5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidines as novel class of potent and highly selective CaMKII inhibitors.

Shigehiro Asano, N. Koike, Y. Isobe, 2010, Bioorganic & medicinal chemistry letters.

Synthesis of pinnaic acid; Asymmetric construction of spirocyclic core

Shigehiro Asano, D. Uemura, H. Arimoto, 1999 .

Crystal Structures and Structure-Activity Relationships of Imidazothiazole Derivatives as IDO1 Inhibitors.

Tetsuya Kohno, Shigehiro Asano, Yosuke Ota, 2014, ACS medicinal chemistry letters.

Suzuki–Miyaura cross-coupling reaction of aryl and heteroaryl pinacol boronates for the synthesis of 2-substituted pyrimidines

Shigehiro Asano, Y. Isobe, S. Kamioka, 2012 .

Total synthesis of allixin; an anti-tumor promoter from garlic

Shigehiro Asano, D. Uemura, H. Arimoto, 1997 .

Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Receptor 9 Antagonists from Scaffold Morphing Efforts.

Shigehiro Asano, H. Tomizawa, K. Eiho, 2014, ACS medicinal chemistry letters.

D-Amino Acid Aminotransferase from a Thermophile, Bacillus SP. YM-1: Enzymological Properties, Cloning of the Gene, and the Amino Acid Sequence

Shigehiro Asano, K. Soda, K. Tanizawa, 1987 .

Development Of Spiral-Type Supported Liquid Membrane Module For Separation And Concentration Of Metal Ions

Shigehiro Asano, H. Matsuyama, M. Teramoto, 1987 .

Synthesis of novel benzo-fused heteroaryl derivatives as Ca²⁺/calmodulin-dependent protein kinase II inhibitors.

Shigehiro Asano, N. Koike, J. Igarashi, 2013, Chemical & pharmaceutical bulletin.

Human Serum Albumin Domain I Fusion Protein for Antibody Conjugation.

R. Fuller, C. Barbas, Shigehiro Asano, 2016, Bioconjugate chemistry.

Preparation and activities of macromolecule conjugates of the CCR5 antagonist Maraviroc.

C. Barbas, D. Burton, Shigehiro Asano, 2014, ACS medicinal chemistry letters.

Synthesis and structure-activity relationships of N-(4-amino-2,6-diisopropylphenyl)-N'-(1,4-diarylpiperidine-4-yl)methylureas as anti-hyperlipidemic agents.

Shigehiro Asano, Hitoshi Ban, K. Ioriya, 2009, Bioorganic & medicinal chemistry.

Novel 1,4-diarylpiperidine-4-methylureas as anti-hyperlipidemic agents: dual effectors on acyl-CoA:cholesterol O-acyltransferase and low-density lipoprotein receptor expression.

Shigehiro Asano, Hitoshi Ban, K. Kino, 2009, Bioorganic & medicinal chemistry letters.

Crystal Structures and Structure-Activity Relationships of Imidazothiazole Derivatives as IDO1 Inhibitors.

Shigehiro Asano, Shingo Tojo, Tetsuya Kohno, 2014, ACS medicinal chemistry letters.

Thermostable D-amino acid aminotransferase from a thermophilic Bacillus species. Purification, characterization, and active site sequence determination.

Shigehiro Asano, H. Tanaka, K. Soda, 1989, The Journal of biological chemistry.

The primary structure of thermostable D-amino acid aminotransferase from a thermophilic Bacillus species and its correlation with L-amino acid aminotransferases.

H. Kagamiyama, Shigehiro Asano, S. Kuramitsu, 1989, The Journal of biological chemistry.