S. Wren

发表

A virtual screening approach to finding novel and potent antagonists at the melanin-concentrating hormone 1 receptor.

D. E. Clark, H. Dyke, C. Higgs, 2004, Journal of medicinal chemistry.

Preparation of novel optical fibre-based Cocaine sensors using a molecular imprinted polymer approach

Kenneth T. V. Grattan, Tong Sun, Stephen P. Wren, 2014 .

A suite of optical fibre-based chemical sensors for environmental monitoring

S. Wren, T. Sun, K. Grattan, 2015, 2015 14th International Conference on Optical Communications and Networks (ICOCN).

Fructose malabsorption: causes, diagnosis and treatment

S. Wren, A. Elshaer, A. Le Gresley, 2021, British Journal of Nutrition.

Thiazolidinediones: An In–Depth Study of Their Synthesis and Application to Medicinal Chemistry in the Treatment of Diabetes Mellitus

S. Wren, A. Le Gresley, Nathan R. Long, 2021, ChemMedChem.

The synthesis and SAR of 2-arylsulfanyl-phenyl piperazinyl acetic acids as glyT-1 inhibitors.

C. Christoffersen, S. Wren, A. Mørk, 2004, Bioorganic & medicinal chemistry letters.

IMMUNO-ONCOLOGY: THE NEXT GENERATION OF BREAKTHROUGH THERAPIES HIGHLIGHTS FROM THE SOCIETY FOR MEDICINES RESEARCH SYMPOSIUM, HELD ON ST 2019

S. Wren, Andy Sykes, J. Ritchie, 2019 .

Immuno-oncology: the next generation of breakthrough therapies. Highlights from The Society for Medicines Research Symposium. Oxford, UK - June 21, 2019

S. Wren, P. Weber, J. Ritchie, 2019, Drugs of the Future.

Novel inhibitors of plasminogen activator inhibitor-1: development of new templates from diketopiperazines.

S. Wren, P. Charlton, J. Golec, 2002, Bioorganic & medicinal chemistry letters.

Discovery of 2-arylbenzoxazoles as upregulators of utrophin production for the treatment of Duchenne muscular dystrophy.

G. Wynne, K. Davies, R. Pye, 2011, Journal of medicinal chemistry.

Discovery and SAR of 2-arylbenzotriazoles and 2-arylindazoles as potential treatments for Duchenne muscular dystrophy.

G. Wynne, R. Pye, S. Wren, 2011, Bioorganic & Medicinal Chemistry Letters.

Quinazoline and benzimidazole MCH-1R antagonists.

S. Cramp, H. Dyke, P. Lockey, 2007, Bioorganic & medicinal chemistry letters.

Novel angular benzophenazines: dual topoisomerase I and topoisomerase II inhibitors as potential anticancer agents.

W. Denny, S. Wren, T. Hancox, 2002, Journal of medicinal chemistry.

Unearthing novel thiazolidinone building blocks as carboxylic acid bioisosteres.

S. Wren, James J Scanlon, 2020, Future medicinal chemistry.

Studies on pyrrolopyrimidines as selective inhibitors of multidrug-resistance-associated protein in multidrug resistance.

Deanne K. Thompson, S. Wren, Irina S. Chuckowree, 2004, Journal of medicinal chemistry.

Treatment of duchenne muscular dystrophy

G. Wynne, R. Pye, S. Wren, 1982 .

Studies on the Stereoselective Synthesis of the Marine Antitumor Agent Eleutherobin

S. Wren, K. Hodgetts, P. Magnus, 2000 .

Studies towards the total synthesis of the marine-derived immunosuppressant discodermolide; asymmetric synthesis of a C1–C8δ-lactone subunit

S. Wren, I. Paterson, 1993 .

Tricyclic Systems: Central Carbocyclic Ring With Fused Five- and Six-Membered Rings

S. Wren, 2020, Reference Module in Chemistry, Molecular Sciences and Chemical Engineering.

Review on molecularly imprinted polymers with a focus on their application to the analysis of protein biomarkers

S. Wren, James Barker, A. Mostafa, 2021, TrAC Trends in Analytical Chemistry.

Silver@graphene oxide nanocomposite-based optical sensor platform for biomolecules

S. Wren, T. Sun, A. Pandikumar, 2015 .

Enzyme inhibition as a potential therapeutic strategy to treat COVID-19 infection

S. Wren, A. K. Snabaitis, Lukas Paulsson-Habegger, 2021, Bioorganic & Medicinal Chemistry.

Daily Treatment with SMTC1100, a Novel Small Molecule Utrophin Upregulator, Dramatically Reduces the Dystrophic Symptoms in the mdx Mouse

K. Davies, S. Wren, A. De Luca, 2011, PloS one.

Structure-activity relationships of a novel series of melanin-concentrating hormone (MCH) receptor antagonists.

Peter Lockey, D. E. Clark, S. Cramp, 2004, Bioorganic & medicinal chemistry letters.

A computational chemistry-driven hypothesis on the mode of action of Hipposudoric Acid and related analogs.

S. Wren, Islam M Araar, 2022, Future medicinal chemistry.

Computational Design and Fabrication of Optical Fibre Fluorescent Chemical Probes for the Detection of Cocaine

S. Wren, K. Grattan, S. Piletsky, 2015, Journal of Lightwave Technology.

Development of magnetic molecularly imprinted polymers for the extraction of salivary pepsin prior to analysis by a novel HPLC-SEC method

S. Wren, James Barker, A. Mostafa, 2022, Polymer.

Suramin analogues protect cartilage against osteoarthritic breakdown by increasing levels of tissue inhibitor of metalloproteinases 3 (TIMP-3) in the tissue.

S. Wren, J. Green, M. Piras, 2023, Bioorganic & medicinal chemistry.

Suramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3

S. Wren, B. Marsden, H. Nagase, 2017, Molecular Pharmacology.

Suramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3

S. Wren, B. Marsden, H. Nagase, 2017, Molecular Pharmacology.

Development of a fiber-optic chemical sensor for the detection of cadmium

Kenneth T. V. Grattan, Tong Sun, Stephen P. Wren, 2016, 2016 IEEE SENSORS.

In silico design of bioisosteric modifications of drugs for the treatment of diabetes.

S. Wren, Jean-Christophe Nebel, Guillaume Vink, 2021, Future medicinal chemistry.