U. Scheffer

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New Inhibitors of the Tat–TAR RNA Interaction Found with a “Fuzzy” Pharmacophore Model

G. Schneider, S. Renner, V. Ludwig, 2005, Chembiochem : a European journal of chemical biology.

Fragment based search for small molecule inhibitors of HIV-1 Tat-TAR.

H. Schwalbe, U. Scheffer, M. Göbel, 2014, Bioorganic & medicinal chemistry letters.

Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS‐CoV‐2 Genome

H. Schwalbe, K. Azzaoui, U. Scheffer, 2021, Angewandte Chemie.

Exploring the Druggability of Conserved RNA Regulatory Elements in the SARS‐CoV‐2 Genome

H. Schwalbe, K. Azzaoui, U. Scheffer, 2021, Angewandte Chemie.

A Cytidine Phosphoramidite with Protected Nitroxide Spin Label: Synthesis of a Full-Length TAR RNA and Investigation by In-Line Probing and EPR Spectroscopy.

U. Scheffer, M. Göbel, T. Prisner, 2018, Chemistry.

Diagnosis of sublethal stress in the marine sponge Geodia cydonium: application of the 70 kDa heat-shock protein and a novel biomarker, the Rab GDP dissociation inhibitor, as probes

U. Scheffer, W. Müller, Z. Pancer, 1997 .

Binding sites of the viral RNA element TAR and of TAR mutants for various peptide ligands, probed with LILBID: A new laser mass spectrometry

U. Scheffer, M. Göbel, N. Morgner, 2008, Journal of the American Society for Mass Spectrometry.

Impairment of intracellular antiviral defense with age: Age-dependent changes in expression of interferon-induced and double-stranded RNA-activated 2–5A synthetase in rat

U. Scheffer, M. Kelve, E. Truve, 1995, Mechanisms of Ageing and Development.

Mode of action of the anti-AIDS compound poly(I).poly(C12U) (Ampligen): activator of 2',5'-oligoadenylate synthetase and double-stranded RNA-dependent kinase.

U. Scheffer, H. Ushijima, W. Müller, 1993, Journal of interferon research.

High conservation of the serum response factor within Metazoa: cDNA from the sponge Geodia cydonium

U. Scheffer, W. Müller, Z. Pancer, 1997 .

Cleavage of Phosphodiesters and of DNA by a Bis(guanidinium)naphthol Acting as a Metal‐Free Anion Receptor

U. Scheffer, J. Bats, Stefan Ullrich, 2011, Chembiochem : a European journal of chemical biology.

Metal-free catalysts for the hydrolysis of RNA derived from guanidines, 2-aminopyridines, and 2-aminobenzimidazoles.

V. Ludwig, U. Scheffer, M. Göbel, 2005, Journal of the American Chemical Society.

A Bis(guanidinium)alcohol Attached to a Hairpin Polyamide: Synthesis, DNA Binding, and Plasmid Cleavage

U. Scheffer, M. Göbel, Stefan Ullrich, 2016, Chembiochem : a European journal of chemical biology.

Phosphoramidite building blocks with protected nitroxides for the synthesis of spin-labeled DNA and RNA

U. Scheffer, M. Göbel, T. Prisner, 2018, Beilstein journal of organic chemistry.

RNA Cleavage Catalyzed by Amphoteric Bis(acyl)guanidinium Derivatives

U. Scheffer, M. Göbel, C. D. Roussev, 2014 .

A peptide template as an allosteric supramolecular catalyst for the cleavage of phosphate esters

C. Toniolo, F. Formaggio, B. Kaptein, 2002, Proceedings of the National Academy of Sciences of the United States of America.

On Facts and Artefacts: The Difficulty to Evaluate an Artificial Nuclease

S. Pitsch, U. Scheffer, M. Göbel, 2003 .

Polymorphism in the immunoglobulin-like domains of the receptor tyrosine kinase from the sponge Geodia cydonium.

P. Kovács, U. Scheffer, W. Müller, 1996, Cell adhesion and communication.

Tripeptides from Synthetic Amino Acids Block the Tat–TAR Association and Slow Down HIV Spread in Cell Cultures

H. Schwalbe, U. Dietrich, V. Ludwig, 2007, Chembiochem : a European journal of chemical biology.

Redirection of miRNA‐Argonaute Complexes to Specific Target Sites by Synthetic Adaptor Molecules

U. Scheffer, M. Göbel, R. Hartmann, 2020, Chemistry & biodiversity.

Interaction of prion protein mRNA with CBP35 and other cellular proteins: possible implications for prion replication and age-dependent changes.

U. Scheffer, W. Müller, S. Perović, 1997, Archives of gerontology and geriatrics.

Interaction of 68-kDa TAR RNA-binding protein and other cellular proteins with prion protein-RNA stem-loop.

U. Scheffer, T. Okamoto, W. Müller, 1995, Journal of neurovirology.

Redirection of the Transcription Factor SP1 to AT Rich Binding Sites by a Synthetic Adaptor Molecule

U. Scheffer, Elisabeth Kalden, Michael W. Göbel, 2021, Helvetica Chimica Acta.

The concept of template-based de novo design from drug-derived molecular fragments and its application to TAR RNA

Gisbert Schneider, Uli Fechner, Andreas Schüller, 2008, J. Comput. Aided Mol. Des..

Cloning of sponge (Geodia cydonium) and tunicate (Botryllus schlosseri) proteasome subunit epsilon (PRCE): implications about the vertebrate MHC-encoded homologue LMP7 (PRCC).

U. Scheffer, W. Müller, I. Müller, 1996, Biochemical and biophysical research communications.

Site-specific cleavage of RNA by a metal-free artificial nuclease attached to antisense oligonucleotides.

U. Scheffer, M. Göbel, S. Klußmann, 2006, Journal of the American Chemical Society.

Site-Specific Cleavage of RNAs Derived from the PIM1 3′-UTR by a Metal-Free Artificial Ribonuclease

U. Scheffer, M. Göbel, R. Hartmann, 2019, Molecules.

Fluorescence correlation spectroscopy at single molecule level on the Tat-TAR complex and its inhibitors.

U. Scheffer, M. Göbel, C. K. Nandi, 2008, Biopolymers.

Scaffold Hopping by “Fuzzy” Pharmacophores and its Application to RNA Targets

Petra Schneider, Gisbert Schneider, Ewgenij Proschak, 2007, Chembiochem : a European journal of chemical biology.