J. Chin

发表

Evolved orthogonal ribosome purification for in vitro characterization

Oliver P. T. Barrett, J. Chin, 2010, Nucleic acids research.

Programming and engineering biological networks.

J. Chin, 2006, Current opinion in structural biology.

Synthesis of orthogonal transcription-translation networks

J. Chin, Wenlin An, 2009, Proceedings of the National Academy of Sciences.

Cellular incorporation of unnatural amino acids and bioorthogonal labeling of proteins.

J. Chin, Kathrin Lang, Kathrin Lang, 2014, Chemical reviews.

Designer proteins: applications of genetic code expansion in cell biology

Jason W. Chin, J. Chin, Lloyd S. Davis, 2012, Nature Reviews Molecular Cell Biology.

Genetically encoded photocontrol of protein localization in mammalian cells.

J. Chin, H. Lusic, Wenlin An, 2010, Journal of the American Chemical Society.

Initial de novo Assemblies of the D. melanogaster genome using long-read PacBio sequencing

Casey M. Bergman, Susan E. Celniker, Jason Chin, 2014 .

Regulation of Cellular Metabolism by Protein Lysine Acetylation

Yixue Li, F. He, J. Chin, 2010, Science.

Reprogramming the genetic code

J. Chin, Daniel de la Torre, 2012, Nature Reviews Genetics.

Reprogramming the genetic code

J. Chin, 2011, The EMBO journal.

A network of orthogonal ribosome·mRNA pairs

J. Chin, O. Rackham, 2005, Nature chemical biology.

Cellular logic with orthogonal ribosomes.

J. Chin, O. Rackham, 2005, Journal of the American Chemical Society.

Engineering Escherichia coli heat-resistance by synthetic gene amplification.

J. Chin, D. Christ, 2008, Protein engineering, design & selection : PEDS.

A Method for Genetically Installing Site-Specific Acetylation in Recombinant Histones Defines the Effects of H3 K56 Acetylation

J. Chin, T. Owen-Hughes, L. Chapman, 2009, Molecular cell.

An Expanded Eukaryotic Genetic Code

Peter G Schultz, P. Schultz, M. Mukherji, 2003, Science.

Encoding multiple unnatural amino acids via evolution of a quadruplet-decoding ribosome

Jason W. Chin, Maria Garcia-Alai, J. Chin, 2010, Nature.

Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions

J. Chin, Kathrin Lang, Lloyd S. Davis, 2012, Journal of the American Chemical Society.

Approaches taken, progress made, and enhanced utility of long read-based goat, swine, cattle and sheep reference genomes

Timothy P. L. Smith, S. Koren, A. Phillippy, 2016 .

Toward an orthogonal central dogma.

Christopher A. Voigt, Michael C Jewett, C. Voigt, 2018, Nature chemical biology.

Modular approaches to expanding the functions of living matter

J. Chin, Jason W Chin, 2006, Nature chemical biology.

Total synthesis of Escherichia coli with a recoded genome

Julius Fredens, Jason W. Chin, J. Chin, 2019, Nature.

Genetic Encoding of Photocaged Cysteine Allows Photoactivation of TEV Protease in Live Mammalian Cells

J. Chin, C. Uttamapinant, D. P. Nguyen, 2014, Journal of the American Chemical Society.

Genetically encoded 1,2-aminothiols facilitate rapid and site-specific protein labeling via a bio-orthogonal cyanobenzothiazole condensation.

T. Muir, J. Chin, D. P. Nguyen, 2011, Journal of the American Chemical Society.

A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation

P. Bastiaens, J. Chin, C. Uttamapinant, 2018, Nature Communications.

A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation

P. Bastiaens, J. Chin, C. Uttamapinant, 2018, bioRxiv.

Genetic code expansion and bioorthogonal labelling enables cell specific proteomics in an animal.

J. Chin, Ambra Bianco, Thomas S. Elliott, 2014, Current opinion in chemical biology.

Bioorthogonal reactions for labeling proteins.

J. Chin, Kathrin Lang, 2014, ACS chemical biology.

Genetic encoding and labeling of aliphatic azides and alkynes in recombinant proteins via a pyrrolysyl-tRNA Synthetase/tRNA(CUA) pair and click chemistry.

J. Chin, H. Lusic, H. Neumann, 2009, Journal of the American Chemical Society.

Translational switching of Cry1 protein expression confers reversible control of circadian behavior in arrhythmic Cry-deficient mice

E. Maywood, M. Hastings, J. Chin, 2018, Proceedings of the National Academy of Sciences.

Fibrinogen anchors for micropatterning of active proteins and subcellular receptor relocalisation

S. Blacklow, E. Derivery, J. Chin, 2020 .

Fibrinogen anchors enable efficient multiplexed patterning of active proteins and subcellular control of membrane-receptor distribution

S. Blacklow, E. Derivery, J. Chin, 2020, bioRxiv.

Expanding the Genetic Code of Yeast for Incorporation of Diverse Unnatural Amino Acids via a Pyrrolysyl-tRNA Synthetase/tRNA Pair

J. Chin, A. Deiters, R. Uprety, 2010, Journal of the American Chemical Society.

RBBP6 activates the pre-mRNA 3′ end processing machinery in humans

J. Chin, L. Passmore, Thomas S. Elliott, 2022, Genes & development.

RBBP6 activates the pre-mRNA 3’-end processing machinery in humans

J. Chin, L. Passmore, T. Elliott, 2021, bioRxiv.

Aurora-A / TACC 3 / Clathrin complexation

J. Chin, F. Gergely, E. Kennedy, 2018 .

EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling

P. Bastiaens, J. Chin, M. Schmick, 2015, eLife.

Synthesis of Isomeric Phosphoubiquitin Chains Reveals that Phosphorylation Controls Deubiquitinase Activity and Specificity

J. Chin, A. Knebel, M. Trost, 2016, Cell reports.

Detecting RNA base methylations in single cells by in situ hybridization

Rohan T Ranasinghe, D. Klenerman, J. Chin, 2018, Nature Communications.

Mechanism-based traps enable protease and hydrolase substrate discovery

M. Freeman, J. Chin, M. Fiedler, 2022, Nature.

Genetically encoding protein oxidative damage.

J. Chin, H. Neumann, R. Mehl, 2008, Journal of the American Chemical Society.

Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

J. Chin, D. Komander, M. Akutsu, 2011, Proceedings of the National Academy of Sciences.

Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7ob01707c

J. Chin, R. Mehl, O. Dmitrenko, 2017, Organic & biomolecular chemistry.

Efficient Phage Display with Multiple Distinct Non‐Canonical Amino Acids Using Orthogonal Ribosome‐Mediated Genetic Code Expansion

J. Chin, Benjamí Oller‐Salvia, 2019, Angewandte Chemie.

Rapid and Efficient Generation of Stable Antibody–Drug Conjugates via an Encoded Cyclopropene and an Inverse‐Electron‐Demand Diels–Alder Reaction

J. Chin, Benjamí Oller‐Salvia, G. Kym, 2018, Angewandte Chemie.

Traceless and Site-Specific Ubiquitination of Recombinant Proteins

J. Chin, L. Riechmann, Kathrin Lang, 2011, Journal of the American Chemical Society.

Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase.

J. Chin, D. Komander, D. P. Nguyen, 2010, Nature chemical biology.

An Evolved Methanomethylophilus alvus Pyrrolysyl-tRNA Synthetase/tRNA Pair Is Highly Active and Orthogonal in Mammalian Cells

Julian C. W. Willis, J. Chin, V. Beránek, 2018, Biochemistry.

Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells

J. Chin, M. Mahesh, John R. James, 2017, Nature Structural & Molecular Biology.

A dual role of H4K16 acetylation in the establishment of yeast silent chromatin

J. Chin, S. Gasser, W. Fischle, 2011, The EMBO journal.

Site-Specific Glycoconjugation of Protein via Bioorthogonal Tetrazine Cycloaddition with a Genetically Encoded trans-Cyclooctene or Bicyclononyne

J. Chin, Kathrin Lang, N. Winssinger, 2015, Bioconjugate chemistry.

Eukaryotic gene regulation

J. Chin, 2000 .

Refactored genetic codes enable bidirectional genetic isolation

G. Salmond, J. Chin, Wesley E. Robertson, 2022, Science.

Efficient genetic encoding of phosphoserine and its nonhydrolyzable analog.

J. Chin, R. Bayliss, A. Kazlauskaite, 2015, Nature chemical biology.

Engineered triply orthogonal pyrrolysyl–tRNA synthetase/tRNA pairs enable the genetic encoding of three distinct non-canonical amino acids

Julian C. W. Willis, J. Chin, Daniel L. Dunkelmann, 2020, Nature Chemistry.

Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release

J. Chin, A. Zhuravleva, R. Bayliss, 2018 .

Bacterial divisome protein FtsA forms curved antiparallel double filaments upon binding FtsN

J. Chin, J. Löwe, S. Freund, 2022, Nature Microbiology.

Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms

J. Chin, K. J. Patel, Koichi Sato, 2020, Nature.

Methodology for optimizing functional miniature proteins based on avian pancreatic polypeptide using phage display.

J. Chin, M. A. Fabian, R. Grotzfeld, 2001, Bioorganic & medicinal chemistry letters.

Mutually orthogonal pyrrolysyl-tRNA synthetase/tRNA pairs

Julian C. W. Willis, J. Chin, 2018, Nature Chemistry.

Protein Expression by Expansion of the Genetic Code

J. Chin, T. Magliery, 2006 .

Selective CRAF Inhibition Elicits Transactivation.

J. Chin, Andrew P Thomas, I. Dale, 2021, Journal of the American Chemical Society.

Gene regulation: Protein escorts to the transcription ball

J. Chin, A. Schepartz, J. Kohler, 1999, Current Biology.

Astrocytic control of extracellular GABA drives circadian timekeeping in the suprachiasmatic nucleus

D. McManus, Y. Li, M. Hastings, 2023, bioRxiv.

Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst† †Dedicated to Professor Stuart L. Schreiber on the occasion of his 60th birthday. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05313k Click here for additional

Stephen J. Walsh, David R Spring, Martin Welch, 2017, Chemical science.

A genetically encoded fluorescent amino acid.

Peter G Schultz, Alexander Deiters, P. Schultz, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Live and let die : Bcl-2 family proteins regulate the intrinsic apoptotic pathway

J. Chin, S. E. Rutledge, Alanna Schepartz, 2022 .

Conformationally Strained trans-Cyclooctene with Improved Stability and Excellent Reactivity in Tetrazine Ligation.

Stephen Wallace, Ryan A Mehl, J. Chin, 2014, Chemical science.

Strain-promoted sydnone bicyclo-[6.1.0]-nonyne cycloaddition

Stephen Wallace, Jason W. Chin, J. Chin, 2014, Chemical science.

Adding amino acids with novel reactivity to the genetic code of Saccharomyces cerevisiae.

P. Schultz, M. Mukherji, J. C. Anderson, 2003, Journal of the American Chemical Society.

Genetic code expansion in the mouse brain.

E. Maywood, M. Hastings, J. Chin, 2016, Nature chemical biology.

Controlling orthogonal ribosome subunit interactions enables evolution of new function

J. Chin, C. Uttamapinant, S. Fried, 2018, Nature.

Ribosome Subunit Stapling for Orthogonal Translation in E. coli

J. Chin, C. Uttamapinant, S. Fried, 2015, Angewandte Chemie.

Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1

Jason W. Chin, J. Chin, C. Uttamapinant, 2014, Journal of the American Chemical Society.

Expanding and reprogramming the genetic code

Jason W. Chin, J. Chin, 2017, Nature.

Expanding and reprogramming the genetic code of cells and animals.

J. Chin, Jason W Chin, 2014, Annual review of biochemistry.

Evolved orthogonal ribosomes enhance the efficiency of synthetic genetic code expansion

J. Chin, H. Neumann, Kaihang Wang, 2007, Nature Biotechnology.

Reprogramming the genetic code

J. Chin, Daniel de la Torre, 2020, Nature reviews. Genetics.

Addition of a photocrosslinking amino acid to the genetic code of Escherichia coli

Andrew B. Martin, P. Schultz, J. Chin, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Genetically programmed cell-based synthesis of non-natural peptide and depsipeptide macrocycles

J. Chin, Wesley E. Robertson, Thomas S. Elliott, 2022, Nature Chemistry.

Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells.

J. Chin, A. Deiters, James Hemphill, 2013, Journal of the American Chemical Society.

In Vivo Photocrosslinking with Unnatural Amino Acid Mutagenesis

P. Schultz, J. Chin, 2002, Chembiochem : a European journal of chemical biology.

Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid

J. Chin, T. Schmeing, D. P. Nguyen, 2018, Nature.

Genetically encoding an aliphatic diazirine for protein photocrosslinking

J. Chin, Lloyd S. Davis, A. Deiters, 2011 .

Selective, rapid and optically switchable regulation of protein function in live mammalian cells.

Jason W. Chin, J. Chin, Kathrin Lang, 2015, Nature chemistry.

Genetically encoding N(epsilon)-methyl-L-lysine in recombinant histones.

J. Chin, H. Neumann, D. P. Nguyen, 2009, Journal of the American Chemical Society.

Addition of p-azido-L-phenylalanine to the genetic code of Escherichia coli.

Andrew B. Martin, Peter G Schultz, P. Schultz, 2002, Journal of the American Chemical Society.

Light-Activated Kinases Enable Temporal Dissection of Signaling Networks in Living Cells

J. Chin, Arnaud Gautier, A. Deiters, 2011, Journal of the American Chemical Society.

DAXX envelops a histone H3.3–H4 dimer for H3.3-specific recognition

D. Patel, C. Allis, J. Chin, 2012, Nature.

Programmed chromosome fission and fusion enable precise large-scale genome rearrangement and assembly

J. Chin, Kaihang Wang, Kaihang Wang, 2019, Science.

Genetic Code Expansion Enables Live-Cell and Super-Resolution Imaging of Site-Specifically Labeled Cellular Proteins

J. Chin, C. Uttamapinant, Kathrin Lang, 2015, Journal of the American Chemical Society.

Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21

J. Chin, L. James, M. Vaysburd, 2018, eLife.

Labeling and identifying cell-specific proteomes in the mouse brain

Marco Tripodi, M. Hastings, J. Chin, 2017, Nature Biotechnology.

Progress toward an expanded eukaryotic genetic code.

P. Schultz, J. Chin, E. Meggers, 2003, Chemistry & biology.

Mitotic spindle association of TACC3 requires Aurora‐A‐dependent stabilization of a cryptic α‐helix

J. Chin, F. Gergely, E. Kennedy, 2018, The EMBO journal.

Genetically encoded optical activation of DNA recombination in human cells† †Electronic supplementary information (ESI) available: Experimental protocols. See DOI: 10.1039/c6cc03934k Click here for additional data file.

J. Chin, E. Arbely, Junshe Zhang, 2016, Chemical communications.

Photocontrol of tyrosine phosphorylation in mammalian cells via genetic encoding of photocaged tyrosine.

Alexander Deiters, J. Chin, E. Arbely, 2012, Journal of the American Chemical Society.

Efficient and Rapid C. elegans Transgenesis by Bombardment and Hygromycin B Selection

J. Chin, S. Greiss, Inja Radman, 2013, PloS one.

Expanding the Genetic Code of an Animal

J. Chin, S. Greiss, Sebastian Greiss, 2011, Journal of the American Chemical Society.

Reprogramming the genetic code: from triplet to quadruplet codes.

J. Chin, Kaihang Wang, Kaihang Wang, 2012, Angewandte Chemie.

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

Torsten Schaller, Greg J. Towers, Jason W. Chin, 2012, PLoS pathogens.

A view to a kill: ligands for Bcl-2 family proteins.

J. Chin, A. Schepartz, S. E. Rutledge, 2002, Current opinion in chemical biology.

Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase–tRNA pairs

Lucy J. Colwell, Julian C. W. Willis, J. Chin, 2020, Nature Biotechnology.

Towards a better understanding of the Coffea Arabica genome structure.

J. Korlach, D. Sankoff, J. Chin, 2015 .

Photo-cross-linking interacting proteins with a genetically encoded benzophenone

J. Chin, R. Mehl, Ian Farrell, 2005, Nature Methods.

Sense codon reassignment enables viral resistance and encoded polymer synthesis

G. Salmond, J. Chin, S. Maslen, 2021, Science.

Conformational transition of FGFR kinase activation revealed by site-specific unnatural amino acid reporter and single molecule FRET

Alan R. Lowe, J. Chin, Y. Alexandrov, 2017, Scientific Reports.

Single Molecule Real Time (SMRT™) Sequencing Sensitively Detects Polyclonal and Compound BCR-ABL in Patients Who Relapse on Kinase Inhibitor Therapy,

A. Kasarskis, E. Schadt, K. Travers, 2011 .

Genetically encoding N(epsilon)-acetyllysine in recombinant proteins.

J. Chin, H. Neumann, Jason W Chin, 2008, Nature chemical biology.

Defining synonymous codon compression schemes by genome recoding

Julius Fredens, Jason W. Chin, J. Chin, 2016, Nature.

Reprogramming the Genetic Code: From Triplet to Quadruplet Codes

Jason W. Chin, J. Chin, Kaihang Wang, 2012 .

A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design

J. Chin, Daniel L. Dunkelmann, S. Oehm, 2021, Nature Chemistry.

A conformational sensor based on genetic code expansion reveals an autocatalytic component in EGFR activation

P. Bastiaens, J. Chin, C. Uttamapinant, 2018, bioRxiv.

Genetic code expansion in stable cell lines enables encoded chromatin modification

Simon J Elsässer, J. Chin, Jason W Chin, 2016, Nature Methods.

An anchored chromosome‐scale genome assembly of spinach improves annotation and reveals extensive gene rearrangements in euasterids

Tyler H. Garvin, M. Schatz, E. Tseng, 2021, The plant genome.

Intein Zymogens: Conditional Assembly and Splicing of Split Inteins via Targeted Proteolysis

Jason W. Chin, Adam J. Stevens, T. Muir, 2017, Journal of the American Chemical Society.

Total synthesis of Escherichia coli with a recoded genome

J. Chin, C. Uttamapinant, Kaihang Wang, 2019, Nature.

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction.

J. Chin, Kathrin Lang, Lloyd S. Davis, 2012, Nature chemistry.

Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration

A. Fersht, C. Robinson, J. Chin, 2011, Proceedings of the National Academy of Sciences.

Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites.

J. Chin, J. Löwe, Louise F. H. Funke, 2021, Molecular cell.

Creating custom synthetic genomes in Escherichia coli with REXER and GENESIS

J. Chin, Kaihang Wang, Julius Fredens, 2021, Nature Protocols.

Proteome labeling and protein identification in specific tissues and at specific developmental stages in an animal

J. Chin, K. Lilley, F. Townsley, 2014, Nature Biotechnology.

Photoactivation of Mutant Isocitrate Dehydrogenase 2 Reveals Rapid Cancer-Associated Metabolic and Epigenetic Changes

S. Balasubramanian, J. Chin, Martin Bachman, 2016, Journal of the American Chemical Society.

Ribosome Subunit Stapling for Orthogonal Translation in E. coli

J. Chin, C. Uttamapinant, S. Fried, 2015, Angewandte Chemie.

Expanding the genetic code of Drosophila melanogaster.

J. Chin, F. Townsley, Kathrin Lang, 2012, Nature chemical biology.

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

J. Chin, L. James, D. Jacques, 2014, PLoS pathogens.

Acetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerization

J. Chin, L. James, H. Neumann, 2010, Nature chemical biology.

Cryo-EM structure of MukBEF reveals DNA loop entrapment at chromosomal unloading sites

J. Chin, J. Löwe, Louise F. H. Funke, 2021, bioRxiv.

Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET

Stephen Wallace, Ryan A Mehl, Amit Sachdeva, 2014, Nature Chemistry.

An Ankyrin-repeat ubiquitin binding domain determines TRABID’s specificity for atypical ubiquitin chains

J. Chin, H. Ovaa, M. Bienz, 2011, Nature Structural &Molecular Biology.

Ubiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerization

J. Chin, M. Bienz, A. Knebel, 2015, Nature Communications.

Expanding nucleic acid function in vitro and in vivo.

J. Chin, T. Cropp, Jason W Chin, 2006, Current opinion in chemical biology.

Structural and Mechanistic Insights into the Regulation of the Fundamental Rho Regulator RhoGDIα by Lysine Acetylation*

U. Baumann, J. Chin, L. James, 2015, The Journal of Biological Chemistry.

Pyrophosphorylation via selective phosphoprotein derivatization† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01233d

J. Chin, D. Fiedler, E. Krause, 2018, Chemical science.

Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase

J. Chin, Lloyd S. Davis, Zhiyan Xi, 2021, eLife.

Precise optical control of gene expression in C. elegans using genetic code expansion and Cre recombinase

J. Chin, Lloyd S. Davis, Zhiyan Xi, 2020, bioRxiv.

Optically splitting symmetric neuron pairs in C. elegans

J. Chin, Lloyd S. Davis, Zhiyan Xi, 2020 .

Substrate recognition by the AAA+ chaperone ClpB

P. Schultz, J. Schneider-Mergener, J. Chin, 2004, Nature Structural &Molecular Biology.

Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons

A. Loudon, M. Hastings, J. Chin, 2022, Proceedings of the National Academy of Sciences.

Concerted, Rapid, Quantitative, and Site-Specific Dual Labeling of Proteins

J. Chin, Kaihang Wang, A. Sachdeva, 2014, Journal of the American Chemical Society.

Orthogonal gene expression in Escherichia coli.

J. Chin, Wenlin An, 2011, Methods in enzymology.

De novo generation of mutually orthogonal aminoacyl-tRNA synthetase/tRNA pairs.

A. Slusarczyk, J. Chin, H. Neumann, 2010, Journal of the American Chemical Society.

Functional epitopes at the ribosome subunit interface

J. Chin, O. Rackham, Kaihang Wang, 2006, Nature chemical biology.

Synthesizing cellular networks from evolved ribosome-mRNA pairs.

J. Chin, O. Rackham, O Rackham, 2006, Biochemical Society transactions.

Ubiquitin C-terminal hydrolases cleave isopeptide- and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers

M. Tatham, J. Chin, R. Hay, 2014, The Biochemical journal.

Genetically Encoded Optochemical Probes for Simultaneous Fluorescence Reporting and Light Activation of Protein Function with Two-Photon Excitation

Alexander Deiters, Jason W. Chin, J. Chin, 2014, Journal of the American Chemical Society.

Genetically Encoded Protein Phosphorylation in Mammalian Cells

J. Chin, Christopher D. Reinkemeier, V. Beránek, 2018, Cell chemical biology.

Design and Evolution of a Miniature Bcl-2 Binding Protein.

J. Chin, A. Schepartz, 2001, Angewandte Chemie.

Biosynthesis and genetic encoding of phosphothreonine through parallel selection and deep sequencing

J. Chin, W. Schmied, Simon F. Brunner, 2017, Nature Methods.

Genetically directing ɛ-N, N-dimethyl-L-lysine in recombinant histones.

Satpal Virdee, J. Chin, D. P. Nguyen, 2010, Chemistry & biology.

The bacterial actin-like cell division protein FtsA forms curved antiparallel double filaments upon binding of FtsN

J. Chin, J. Löwe, S. Freund, 2021, bioRxiv.

Tagging and Enriching Proteins Enables Cell-Specific Proteomics

J. Chin, F. Townsley, S. Fried, 2016, Cell chemical biology.

Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase–tRNA pairs

Lucy J. Colwell, Julian C. W. Willis, J. Chin, 2020, Nature Biotechnology.

Validation of FLT3-ITD As a Therapeutic Target in Human Acute Myeloid Leukemia

A. Kasarskis, E. Schadt, K. Travers, 2011 .

Fluorescent imaging: Shining a light into live cells.

J. Chin, Kathrin Lang, 2013, Nature chemistry.

Reprogramming the amino-acid substrate specificity of orthogonal aminoacyl-tRNA synthetases to expand the genetic code of eukaryotic cells

J. Chin, T. Cropp, J Christopher Anderson, 2007, Nature Protocols.

Cryptochrome 1 as a state variable of the circadian clockwork of the suprachiasmatic nucleus: Evidence from translational switching

E. Maywood, M. Hastings, J. Chin, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Cell-of-origin–specific proteomics of extracellular vesicles

Martin L. Miller, J. Chin, S. Kehrloesser, 2023, PNAS nexus.

Engineered Diubiquitin Synthesis Reveals K29-Isopeptide Specificity of an Otu Deubiquitinase

J. Chin, D. Komander, D. P. Nguyen, 2010 .

High-efficacy subcellular micropatterning of proteins using fibrinogen anchors

S. Blacklow, E. Derivery, J. Chin, 2021, The Journal of cell biology.

Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release

J. Chin, A. Zhuravleva, R. Bayliss, 2018, Science Signaling.

Constitutively Activating Mutations At the FLT3 Activation Loop Residue D835 Are Associated with Clinical Resistance to AC220

A. Kasarskis, K. Travers, J. Radich, 2012 .

Concerted evolution of structure and function in a miniature protein.

J. Chin, A. Schepartz, 2001, Journal of the American Chemical Society.

Genetic encoding of unnatural amino acids for labeling proteins.

J. Chin, Kathrin Lang, Lloyd S. Davis, 2015, Methods in molecular biology.

Pyrophosphorylation via selective phosphoprotein derivatization† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01233d

J. Chin, D. Fiedler, E. Krause, 2018, Chemical science.

Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly

J. Chin, J. Sale, Askar A. Kleefeldt, 2023, Nature.

Quintuply orthogonal pyrrolysyl-tRNA synthetase/tRNAPyl pairs

J. Chin, Daniel L. Dunkelmann, Adam T. Beattie, 2023, Nature Chemistry.

Acetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerization

J. Chin, L. James, H. Neumann, 2010, Nature chemical biology.

Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells.

J. Chin, A. Deiters, James Hemphill, 2013, Journal of the American Chemical Society.

Design and Evolution of a Miniature Bcl-2 Binding Protein.

J. Chin, A. Schepartz, 2001, Angewandte Chemie.

Regulation of Cellular Metabolism by Protein Lysine Acetylation

Yixue Li, F. He, J. Chin, 2010, Science.

Genetically directing ɛ-N, N-dimethyl-L-lysine in recombinant histones.

J. Chin, D. P. Nguyen, M. G. Garcia Alai, 2010, Chemistry & biology.

Stephen J. Walsh, D. Spring, M. Welch, 2017, Chemical science.

Discovery and Genetic Code Expansion of a Polyethylene Terephthalate (PET) Hydrolase from the Human Saliva Metagenome for the Degradation and Bio-Functionalization of PET

M. Madan Babu, J. Chin, C. Uttamapinant, 2022, Angewandte Chemie.

Cellular incorporation of unnatural amino acids and bioorthogonal labeling of proteins.

J. Chin, Kathrin Lang, 2014, Chemical reviews.

Computationally guided discovery of a reactive, hydrophilic trans-5-oxocene dienophile for bioorthogonal labeling

J. Chin, R. Mehl, O. Dmitrenko, 2017, Organic & biomolecular chemistry.

Solvay Public Lectures New Chemistry and New Opportunities from the Expanding Protein Universe

J. Chin, J. Frank, 2013 .

Photocontrol of tyrosine phosphorylation in mammalian cells via genetic encoding of photocaged tyrosine.

J. Chin, E. Arbely, A. Deiters, 2012, Journal of the American Chemical Society.

Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase.

J. Chin, D. Komander, D. P. Nguyen, 2010, Nature chemical biology.

A dual role of H4K16 acetylation in the establishment of yeast silent chromatin

J. Chin, S. Gasser, W. Fischle, 2011, The EMBO journal.

Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells

J. Chin, M. Mahesh, John R. James, 2017, Nature Structural & Molecular Biology.