R. Gladding

发表

Kinetic analysis in human brain of [11C](R)-rolipram, a positron emission tomographic radioligand to image phosphodiesterase 4: A retest study and use of an image-derived input function

Masahiro Fujita, Robert B. Innis, Victor W. Pike, 2011, NeuroImage.

In vitro and in vivo evaluation of 11 CSD 5024 , a novel PET radioligand for human brain imaging of cannabinoid CB 1 receptors ☆ O F

Sean R. Donohue, Kimberly J. Jenko, C. Halldin, 2013 .

Synthesis and Evaluation of Translocator 18 kDa Protein (TSPO) Positron Emission Tomography (PET) Radioligands with Low Binding Sensitivity to Human Single Nucleotide Polymorphism rs6971

Kimberly J. Jenko, F. Da Settimo, S. Taliani, 2014, ACS chemical neuroscience.

11C-LY2428703, a positron emission tomographic radioligand for the metabotropic glutamate receptor 1, is unsuitable for imaging in monkey and human brains

E. Nisenbaum, P. Zanotti-Fregonara, S. Zoghbi, 2013, EJNMMI Research.

Synthesis and characterization in monkey of [11C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors

S. Zoghbi, J. Liow, R. Gladding, 2012, European Journal of Nuclear Medicine and Molecular Imaging.

Discovery, Radiolabeling, and Evaluation of Subtype-Selective Inhibitors for Positron Emission Tomography Imaging of Brain Phosphodiesterase-4D.

M. Gurney, S. Zoghbi, J. Liow, 2020, ACS chemical neuroscience.

Loperamide and its N-desmethyl radiometabolite are avid substrates for brain P-glycoprotein efflux

F. Yasuno, S. Zoghbi, J. Liow, 2007 .

Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors.

C. Halldin, S. Zoghbi, J. Liow, 2019, Nuclear medicine and biology.

Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.

Kimberly J. Jenko, S. Zoghbi, J. Liow, 2012, Journal of medicinal chemistry.

PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study

S. Zoghbi, J. Liow, R. Gladding, 2020, Journal of Neuroinflammation.

[18F]PS-2 as a candidate radioligand for imaging COX-1 expression in brain: radiosynthesis and monkey PET imaging

Kimberly J. Jenko, S. Zoghbi, R. Gladding, 2015 .

Synthesis of [18F]PS13 and Evaluation as a PET Radioligand for Cyclooxygenase-1 in Monkey.

P. Zanotti-Fregonara, S. Zoghbi, J. Liow, 2021, ACS chemical neuroscience.

[O-methyl-11C]N-(4-(4-(3-Chloro-2-methoxyphenyl)-piperazin-1-yl)butyl)-1H-indole-2-carboxamide ([11C]BAK4-51) Is an Efflux Transporter Substrate and Ineffective for PET Imaging of Brain D3 Receptors in Rodents and Monkey

S. Zoghbi, J. Liow, R. Gladding, 2018, Molecules.

In Vivo Evaluation of 6 Analogs of 11C-ER176 as Candidate 18F-Labeled Radioligands for 18-kDa Translocator Protein

S. Zoghbi, J. Liow, R. Gladding, 2022, The Journal of Nuclear Medicine.

Quantification of serotonin 5-HT1A receptors in monkey brain with [11C](−)-RWAY

F. Yasuno, S. Zoghbi, R. Gladding, 2006, NeuroImage.

11C-Loperamide and Its N-Desmethyl Radiometabolite Are Avid Substrates for Brain Permeability-Glycoprotein Efflux

Jeih-San Liow, Fumihiko Yasuno, Sami S Zoghbi, 2008, Journal of Nuclear Medicine.

Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function.

Jeih-San Liow, Nicholas Seneca, Sami S Zoghbi, 2008, Journal of medicinal chemistry.

Evaluation of a PET Radioligand to Image O-GlcNAcase in Brain and Periphery of Rhesus Monkey and Knock-Out Mouse

P. Zanotti-Fregonara, S. Zoghbi, J. Liow, 2018, The Journal of Nuclear Medicine.

PET ligands [18F]LSN3316612 and [11C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain

S. Zoghbi, J. Liow, R. Gladding, 2020, Science Translational Medicine.

The PET Radioligand 18F-FIMX Images and Quantifies Metabotropic Glutamate Receptor 1 in Proportion to the Regional Density of Its Gene Transcript in Human Brain

Jeih-San Liow, Mattia Veronese, Jinsoo Hong, 2016, The Journal of Nuclear Medicine.

Brain and Whole-Body Imaging in Rhesus Monkeys of 11C-NOP-1A, a Promising PET Radioligand for Nociceptin/Orphanin FQ Peptide Receptors

Yasuyuki Kimura, Talakad G. Lohith, Sami S Zoghbi, 2011, The Journal of Nuclear Medicine.

The PET Radioligand [11C]MePPEP Binds Reversibly and with High Specific Signal to Cannabinoid CB1 Receptors in Nonhuman Primate Brain

Christer Halldin, Fumihiko Yasuno, Eyassu Chernet, 2008, Neuropsychopharmacology.

Synthesis and evaluation in monkey of [(18)F]4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX): a promising radioligand for PET imaging of brain metabotropic glutamate receptor 1 (mGluR1).

Paolo Zanotti-Fregonara, Sami S Zoghbi, Victor W Pike, 2013, Journal of medicinal chemistry.

Evaluation of Two Potent and Selective PET Radioligands to Image COX-1 and COX-2 in Rhesus Monkeys

Jeih-San Liow, Robert B. Innis, Victor W. Pike, 2018, The Journal of Nuclear Medicine.

In vitro and in vivo evaluation of 11C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors

Masahiro Fujita, Robert B. Innis, Victor W. Pike, 2014, NeuroImage.

Comparison of [11C]-(R)-PK 11195 and [11C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker

Masahiro Fujita, Cheryl L. Morse, Robert B. Innis, 2010, NeuroImage.

11C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α1 Adrenoceptors in Brain

Jeih-San Liow, Shuiyu Lu, Per Svenningsson, 2014, The Journal of Nuclear Medicine.

Selectivity in rodents and monkeys of 11C-CUMI-101, an agonist radioligand for serotonin 5-HT1A receptors

R. Parsey, J. Hirvonen, S. Zoghbi, 2010 .

Brain and whole-body imaging in nonhuman primates with [11C]MeS-IMPY, a candidate radioligand for beta-amyloid plaques.

Lisheng Cai, Jeih-San Liow, Nicholas Seneca, 2007, Nuclear medicine and biology.

Low Retention of [S-methyl-11C]MeS-IMPY to β-amyloid Plaques in Patients with Alzheimers Disease

P. Aisen, S. Zoghbi, J. Liow, 2009 .

PET measurement of cyclooxygenase-2 using a novel radioligand: upregulation in primate neuroinflammation and first-in-human study

S. Zoghbi, J. Liow, R. Gladding, 2020, Journal of Neuroinflammation.

Imaging and Quantitation of Cannabinoid CB1 Receptors in Human and Monkey Brains Using 18F-Labeled Inverse Agonist Radioligands

Jeih-San Liow, Cheryl L. Morse, Robert B. Innis, 2010, Journal of Nuclear Medicine.

P-Glycoprotein Function at the Blood–Brain Barrier Imaged Using 11C-N-Desmethyl-Loperamide in Monkeys

P. Herscovitch, S. Zoghbi, J. Liow, 2008, Journal of Nuclear Medicine.

Synthesis and Evaluation of N-Methyl and S-Methyl 11C-Labeled 6-Methylthio-2-(4′-N,N-dimethylamino)phenylimidazo[1,2-a]pyridines as Radioligands for Imaging β-Amyloid Plaques in Alzheimer’s Disease

S. Zoghbi, J. Liow, R. Gladding, 2008 .

[11C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain

B. Richmond, P. Zanotti-Fregonara, S. Zoghbi, 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Human Brain Imaging and Radiation Dosimetry of 11C-N-Desmethyl-Loperamide, a PET Radiotracer to Measure the Function of P-Glycoprotein

Jeih-San Liow, Peter Herscovitch, Nicholas Seneca, 2009, Journal of Nuclear Medicine.

Synthesis and Screening in Mice of Fluorine-Containing PET Radioligands for TSPO: Discovery of a Promising 18F-Labeled Ligand.

F. Da Settimo, S. Taliani, C. Martini, 2021, Journal of medicinal chemistry.

Fluoxetine administered to juvenile monkeys: effects on the serotonin transporter and behavior.

E. Leibenluft, P. Svenningsson, J. Winslow, 2014, The American journal of psychiatry.

Evaluation in monkey of two candidate PET radioligands, [11C]RX‐1 and [18F]RX‐2, for imaging brain 5‐HT4 receptors

Talakad G. Lohith, Masahiro Fujita, Rong Xu, 2014, Synapse.

Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain

Masahiro Fujita, Masao Imaizumi, Emmanuelle Briard, 2007, Synapse.

Quantification of serotonin 5‐HT1A receptors in monkey brain with [11C](R)‐(−)‐RWAY

F. Yasuno, S. Zoghbi, R. Gladding, 2006, Synapse.

Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA, a dopamine agonist radioligand

D. Sibley, C. Halldin, J. Liow, 2008, NeuroImage.

Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors.

C. Halldin, S. Zoghbi, J. Liow, 2019, Nuclear Medicine and Biology.

Kinetic analysis in human brain of [11C](R)-rolipram, a positron emission tomographic radioligand to image phosphodiesterase 4: A retest study and use of an image-derived input function

R. Boellaard, P. Zanotti-Fregonara, S. Zoghbi, 2011, NeuroImage.

[carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain.

Kimberly J. Jenko, S. Zoghbi, J. Liow, 2015, Nuclear medicine and biology.

Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function.

S. Zoghbi, J. Liow, R. Gladding, 2008, Journal of medicinal chemistry.

In vitro and in vivo evaluation of 11C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors

Sean R. Donohue, Kimberly J. Jenko, C. Halldin, 2014, NeuroImage.