Jinsoo Hong

发表

Effects of cAMP‐dependent protein kinase activator and inhibitor on in vivo rolipram binding to phosphodiesterase 4 in conscious rats

V. Pike, R. Innis, M. Fujita, 2010, Synapse.

Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors

Masahiro Fujita, Robert B. Innis, Victor W. Pike, 2008, NeuroImage.

PET imaging with [ 11 C ] PBR 28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat

M. Imaizumi, S. Zoghbi, V. Pike, 2006 .

Radiation Dosimetry and Biodistribution in Monkey and Man of 11C-PBR28: A PET Radioligand to Image Inflammation

Jeih-San Liow, Yota Fujimura, Victor W Pike, 2007, Journal of Nuclear Medicine.

Evaluation of [11C]S14506 and [18F]S14506 in rat and monkey as agonist PET radioligands for brain 5-HT1A receptors

S. Zoghbi, J. Liow, V. Pike, 2010 .

Alternative methods for labeling the 5-HT1A receptor agonist, 1-[2-(4-fluorobenzoylamino)ethyl]-4-(7-methoxynaphthyl)piperazine (S14506), with carbon-11 or fluorine-18

H. Wikström, V. Pike, Jinsoo Hong, 2005 .

Investigation of the Metabolites of (S,S)-[11C]MeNER in Humans, Monkeys and Rats

B. Gulyás, C. Halldin, S. Zoghbi, 2008, Molecular Imaging and Biology.

Building a database for brain 18 kDa translocator protein imaged using [11C]PBR28 in healthy subjects

R. Gunn, P. Zanotti-Fregonara, S. Zoghbi, 2019, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.

Talakad G. Lohith, E. Rabiner, R. Gunn, 2011, Journal of medicinal chemistry.

PET imaging with [ 11 C ] PBR 28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat

M. Imaizumi, S. Zoghbi, V. Pike, 2006 .

Synthesis and characterization in monkey of [11C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors

S. Zoghbi, J. Liow, R. Gladding, 2012, European Journal of Nuclear Medicine and Molecular Imaging.

Occupancy of dopamine D2/3 receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [11C]MNPA

D. Sibley, C. Halldin, S. Zoghbi, 2008, Synapse.

Discovery, Radiolabeling, and Evaluation of Subtype-Selective Inhibitors for Positron Emission Tomography Imaging of Brain Phosphodiesterase-4D.

M. Gurney, S. Zoghbi, J. Liow, 2020, ACS chemical neuroscience.

Loperamide and its N-desmethyl radiometabolite are avid substrates for brain P-glycoprotein efflux

F. Yasuno, S. Zoghbi, J. Liow, 2007 .

First-in-human evaluation of [11C]PS13, a novel PET radioligand, to quantify cyclooxygenase-1 in the brain

S. Zoghbi, J. Liow, V. Pike, 2020, European Journal of Nuclear Medicine and Molecular Imaging.

In vivo and in vitro measurement of brain phosphodiesterase 4 in rats after antidepressant administration

Matthew S. Crescenzo, Michael V. Green, M. Imaizumi, 2007, Synapse.

Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I

J. Seidel, C. Halldin, S. Zoghbi, 2007, European Journal of Nuclear Medicine and Molecular Imaging.

PET Measurement of the In Vivo Affinity of 11C-(R)-Rolipram and the Density of Its Target, Phosphodiesterase-4, in the Brains of Conscious and Anesthetized Rats

M. Imaizumi, S. Zoghbi, V. Pike, 2009, Journal of Nuclear Medicine.

Synthesis of NCA [carbonyl‐11C]amides by direct reaction of in situ generated [11C]carboxymagnesium halides with amines under microwave‐enhanced conditions

V. Pike, Jinsoo Hong, Shuiyu Lu, 2003 .

PET Reveals Inflammation around Calcified Taenia solium Granulomas with Perilesional Edema

S. Zoghbi, V. Pike, R. Innis, 2013, PloS one.

Synthesis, structure-affinity relationships, and radiolabeling of selective high-affinity 5-HT4 receptor ligands as prospective imaging probes for positron emission tomography.

V. Pike, Jinsoo Hong, C. Morse, 2010, Journal of medicinal chemistry.

Radiolabeling of a high potency cannabinoid subtype‐1 receptor ligand, N‐(4‐fluoro‐benzyl)‐4‐(3‐(piperidin‐1‐yl)‐indole‐1‐sulfonyl)benzamide (PipISB), with carbon‐11 or fluorine‐18

Sean R. Donohue, S. Hitchcock, C. Halldin, 2008 .

Dopamine β‐hydroxylase‐deficient mice have normal densities of D2 dopamine receptors in the high‐affinity state based on in vivo PET imaging and in vitro radioligand binding

D. Sibley, C. Halldin, J. Liow, 2010, Synapse.

Evaluation of [C]S14506 and [F]S14506 in rat and monkey as agonist PET radioligands for brain 5-HT(1A) receptors.

S. Zoghbi, J. Liow, V. Pike, 2010, Current radiopharmaceuticals.

Synthesis and evaluation of radioligands for imaging brain nociceptin/orphanin FQ peptide (NOP) receptors with positron emission tomography.

Robert B. Innis, Victor W. Pike, Johannes T. Tauscher, 2011, Journal of medicinal chemistry.

Synthesis and evaluation in monkey of two sensitive 11C-labeled aryloxyanilide ligands for imaging brain peripheral benzodiazepine receptors in vivo.

Sami S Zoghbi, Victor W Pike, Robert B Innis, 2008, Journal of medicinal chemistry.

[carbonyl-C]Benzyl acetate: automated radiosynthesis via Pd-mediated [C]carbon monoxide chemistry and PET measurement of brain uptake in monkey.

V. Pike, R. Innis, M. Fujita, 2010, Journal of labelled compounds & radiopharmaceuticals.

Effect of a P‐glycoprotein inhibitor, cyclosporin A, on the disposition in rodent brain and blood of the 5‐HT1A receptor radioligand, [11C](R)‐(––)‐RWAY

Jeih-San Liow, Shuiyu Lu, Sami S Zoghbi, 2007, Synapse.

11C-Loperamide and Its N-Desmethyl Radiometabolite Are Avid Substrates for Brain Permeability-Glycoprotein Efflux

Jeih-San Liow, Fumihiko Yasuno, Sami S Zoghbi, 2008, Journal of Nuclear Medicine.

Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function.

Jeih-San Liow, Nicholas Seneca, Sami S Zoghbi, 2008, Journal of medicinal chemistry.

Neuroinflammation in Temporal Lobe Epilepsy Measured Using Positron Emission Tomographic Imaging of Translocator Protein.

Kimberly J. Jenko, S. Inati, J. Hirvonen, 2015, JAMA neurology.

PET imaging with [11C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat

Robert B. Innis, Victor W. Pike, Sami S. Zoghbi, 2007, Neuroscience Letters.

The PET Radioligand 18F-FIMX Images and Quantifies Metabotropic Glutamate Receptor 1 in Proportion to the Regional Density of Its Gene Transcript in Human Brain

Jeih-San Liow, Mattia Veronese, Jinsoo Hong, 2016, The Journal of Nuclear Medicine.

Brain and Whole-Body Imaging in Rhesus Monkeys of 11C-NOP-1A, a Promising PET Radioligand for Nociceptin/Orphanin FQ Peptide Receptors

Yasuyuki Kimura, Talakad G. Lohith, Sami S Zoghbi, 2011, The Journal of Nuclear Medicine.

The PET Radioligand [11C]MePPEP Binds Reversibly and with High Specific Signal to Cannabinoid CB1 Receptors in Nonhuman Primate Brain

Christer Halldin, Fumihiko Yasuno, Eyassu Chernet, 2008, Neuropsychopharmacology.

In vitro and in vivo evaluation of 11C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors

Masahiro Fujita, Robert B. Innis, Victor W. Pike, 2014, NeuroImage.

Comparison of [11C]-(R)-PK 11195 and [11C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarker

Masahiro Fujita, Cheryl L. Morse, Robert B. Innis, 2010, NeuroImage.

Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand

Jeih-San Liow, Cheryl L. Morse, Robert B. Innis, 2009, NeuroImage.

Brain and whole-body imaging in nonhuman primates with [11C]MeS-IMPY, a candidate radioligand for beta-amyloid plaques.

Lisheng Cai, Jeih-San Liow, Nicholas Seneca, 2007, Nuclear medicine and biology.

PET imaging of brain with the β-amyloid probe, [11C]6-OH-BTA-1, in a transgenic mouse model of Alzheimer’s disease

Michael V. Green, D. Jacobowitz, K. Katada, 2005, European Journal of Nuclear Medicine and Molecular Imaging.

Low Retention of [S-methyl-11C]MeS-IMPY to β-amyloid Plaques in Patients with Alzheimers Disease

P. Aisen, S. Zoghbi, J. Liow, 2009 .

Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation

Robert B. Innis, Victor W. Pike, Sami S. Zoghbi, 2008, NeuroImage.

D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: A PET study in a receptor internalization-deficient mouse model

Jeih-San Liow, Robert B. Innis, Victor W. Pike, 2010, NeuroImage.

cAMP Signaling in Brain is Decreased in Unmedicated Depressed Patients and Increased by Treatment with a Selective Serotonin Reuptake Inhibitor

Robert B. Innis, Victor W. Pike, Sami S. Zoghbi, 2016, Molecular Psychiatry.

Disulfiram Inhibits Defluorination of 18F-FCWAY, Reduces Bone Radioactivity, and Enhances Visualization of Radioligand Binding to Serotonin 5-HT1A Receptors in Human Brain

Jeih-San Liow, Jerry Collins, Victor W Pike, 2007, Journal of Nuclear Medicine.

In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomography

S. Zoghbi, V. Pike, R. Innis, 2010, Synapse.

Quantification of brain phosphodiesterase 4 in rat with (R)-[11C]Rolipram-PET

Masahiro Fujita, Jeih-San Liow, Robert B. Innis, 2005, NeuroImage.

Syntheses of 11C- and 18F-labeled carboxylic esters within a hydrodynamically-driven micro-reactor.

Paul Watts, Frederick T Chin, Victor W Pike, 2004, Lab on a chip.

Synthesis and Evaluation of N-Methyl and S-Methyl 11C-Labeled 6-Methylthio-2-(4′-N,N-dimethylamino)phenylimidazo[1,2-a]pyridines as Radioligands for Imaging β-Amyloid Plaques in Alzheimer’s Disease

S. Zoghbi, J. Liow, R. Gladding, 2008 .

Translation of 11C-labeled tracer synthesis to a CGMP environment as exemplified by [11C]ER176 for PET imaging of human TSPO

V. Pike, Jinsoo Hong, C. Morse, 2021, Nature Protocols.

Quantification of serotonin 5‐HT1A receptors in humans with [11C](R)‐(−)‐RWAY: Radiometabolite(s) likely confound brain measurements

F. Yasuno, S. Zoghbi, J. Liow, 2007, Synapse.

Kinetic evaluation in nonhuman primates of two new PET ligands for peripheral benzodiazepine receptors in brain

Masahiro Fujita, Masao Imaizumi, Emmanuelle Briard, 2007, Synapse.

Quantification of serotonin 5‐HT1A receptors in monkey brain with [11C](R)‐(−)‐RWAY

F. Yasuno, S. Zoghbi, R. Gladding, 2006, Synapse.

[carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain.

Kimberly J. Jenko, S. Zoghbi, J. Liow, 2015, Nuclear medicine and biology.

Synthesis and evaluation of [N-methyl-11C]N-desmethyl-loperamide as a new and improved PET radiotracer for imaging P-gp function.

S. Zoghbi, J. Liow, R. Gladding, 2008, Journal of medicinal chemistry.

Development of new brain imaging agents based upon nocaine-modafinil hybrid monoamine transporter inhibitors.

C. Halldin, J. Liow, V. Pike, 2006, Bioorganic & medicinal chemistry letters.

In vitro and in vivo evaluation of 11C-SD5024, a novel PET radioligand for human brain imaging of cannabinoid CB1 receptors

Sean R. Donohue, Kimberly J. Jenko, C. Halldin, 2014, NeuroImage.

Building a database for brain 18 kDa translocator protein imaged using [11C]PBR28 in healthy subjects

R. Gunn, P. Zanotti-Fregonara, S. Zoghbi, 2019, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

RESEARCH ARTICLE Investigation of the Metabolites of (S,S)-( 11 C) MeNER in Humans, Monkeys and Rats

Jeih-San Liow, Robert B. Innis, Victor W. Pike, 2009 .