N. Sarvetnick

发表

Innate immunity and autoimmunity: from self-protection to self-destruction.

F. Shi, H. Ljunggren, N. Sarvetnick, 2001, Trends in immunology.

Presented antigen from damaged pancreatic beta cells activates autoreactive T cells in virus-mediated autoimmune diabetes.

N. Sarvetnick, M. Horwitz, A. Ilic, 2002, The Journal of clinical investigation.

Organ-specific autoimmunity.

N. Sarvetnick, C. King, 1997, Current opinion in immunology.

Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice

N. Sarvetnick, R. Mueller, T. Krahl, 1996, The Journal of experimental medicine.

Inhibition of Autophagic Turnover in β-Cells by Fatty Acids and Glucose Leads to Apoptotic Cell Death*

N. Sarvetnick, Shakeel U. R. Mir, N. George, 2014, The Journal of Biological Chemistry.

Cytokines: promoters and dampeners of autoimmunity.

N. Sarvetnick, N. Hill, 2002, Current opinion in immunology.

Diabetogenic T Cells from Transgenic Decarboxylase 65 Sequence, that Stimulate Peptide Ligands, Including a Glutamic Acid Identification of MHC Class II-Restricted

N. Sarvetnick, C. Pinilla, Darcy B. Wilson, 2013 .

Local Delivery of Interleukin 4 by Retrovirus-Transduced T Lymphocytes Ameliorates Experimental Autoimmune Encephalomyelitis

G. Nolan, N. Sarvetnick, L. Steinman, 1997, The Journal of experimental medicine.

Effect on insulin production sorting and secretion by major histocompatibility complex class II gene expression in the pancreatic beta-cell of transgenic mice.

N. Sarvetnick, G. Grodsky, B. Cullen, 1992, Endocrinology.

Transgenic mouse models for growth factor studies.

N. Sarvetnick, 1991, Methods in enzymology.

Transgenic mice for the study of diabetes mellitus

N. Sarvetnick, J. Shizuru, 1991, Trends in Endocrinology & Metabolism.

B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice.

N. Sarvetnick, J. Lee, M. Falcone, 1998, Journal of immunology.

Interleukin (IL)-18 Binding Protein Deficiency Disrupts Natural Killer Cell Maturation and Diminishes Circulating IL-18

N. Sarvetnick, Robert Z. Harms, A. J. Creer, 2017, Front. Immunol..

PDX-1 and Msx-2 expression in the regenerating and developing pancreas.

N. Sarvetnick, C. Wright, H. Fox, 1999, The Journal of endocrinology.

Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes–prone mice

A. Tobin, N. Sarvetnick, M. Atkinson, 1996, Nature Medicine.

RNase L and Double-Stranded RNA-Dependent Protein Kinase Exert Complementary Roles in Islet Cell Defense during Coxsackievirus Infection1

Monica Hultcrantz, Robert Silverman, R. Silverman, 2005, The Journal of Immunology.

A critical role for inducible nitric oxide synthase in host survival following coxsackievirus B4 infection.

N. Sarvetnick, D. Balakrishna, M. Horwitz, 2001, Virology.

Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells.

N. Sarvetnick, C. Fine, M. Flodström, 2003, Diabetes.

Nodal and lefty signaling regulates the growth of pancreatic cells

N. Sarvetnick, A. Stotland, H. Hua, 2008, Developmental dynamics : an official publication of the American Association of Anatomists.

Inhibition of activin signaling induces pancreatic epithelial cell expansion and diminishes terminal differentiation of pancreatic beta-cells.

N. Sarvetnick, S. Dabernat, A. Kayali, 2004, Diabetes.

Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers.

J. Meza, L. Loeb, P. Welcsh, 2013, Translational Oncology.

Altered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers.

J. Meza, L. Loeb, P. Welcsh, 2013, Translational oncology.

The influence of cytokines on the central nervous system of transgenic mice.

N. Sarvetnick, K. Geiger, 1996, Current topics in microbiology and immunology.

Lymphocyte proliferation in immune-mediated diseases.

N. Sarvetnick, Shrimati Datta, 2009, Trends in immunology.

The target tissue in autoimmunity – an influential niche

N. Sarvetnick, M. Hultcrantz, M. Flodström-Tullberg, 2007, European journal of immunology.

CD8+ T Cell Tolerance in Nonobese Diabetic Mice Is Restored by Insulin-Dependent Diabetes Resistance Alleles1

N. Sarvetnick, L. Wicker, H. Rosen, 2005, The Journal of Immunology.

CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice.

R. Tisch, H. Mcdevitt, N. Sarvetnick, 1997, Journal of immunology.

Confirmation and Identification of Biomarkers Implicating Environmental Triggers in the Pathogenesis of Type 1 Diabetes

N. Sarvetnick, Robert Z. Harms, Katie R. Ostlund, 2020, Frontiers in Immunology.

Tyrosine kinase receptors are crucial for normal β-cell development and function

N. Sarvetnick, S. Arnaud-Dabernat, 2007, Expert review of endocrinology & metabolism.

Transitional cells in the regenerating pancreas.

N. Sarvetnick, T. Krahl, M. S. Lee, 1994, Development.

Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes

E. Getzoff, N. Sarvetnick, A. Stotland, 2007, Biology Direct.

Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis.

N. Sarvetnick, I. Verma, T. Kafri, 1998, Human gene therapy.

PYY in the expanding pancreatic epithelium

N. Sarvetnick, A. Kayali, M. Kritzik, 2006, Endocrine.

Mechanisms of cytokine-mediated localized immunoprotection

N. Sarvetnick, 1996, The Journal of experimental medicine.

The role of cytokines in autoimmunity.

N. Sarvetnick, A. La Cava, 1999, Current directions in autoimmunity.

The role of infiltrating macrophages in islet destruction and regrowth in a transgenic model.

A. Cooke, N. Sarvetnick, L. O'Reilly, 1995, Journal of autoimmunity.

Myasthenia gravis-like syndrome induced by expression of interferon gamma in the neuromuscular junction

N. Calcutt, N. Sarvetnick, J. Merlie, 1995, The Journal of experimental medicine.

11 – Immunological Studies Utilizing Cytokine Transgenic Mice

N. Sarvetnick, Myung-Shik Lee, 1994 .

Murine Transgenic Models of IDDM

N. Sarvetnick, D. Gu, 1994 .

Inflammatory Destruction of Pancreatic Islets in Interferon Gamma Transgenic Mice

N. Sarvetnick, D. Liggitt, T. Stewart, 1989 .

The pathogenesis of diabetes in the NOD mouse.

N. Sarvetnick, Michelle F Solomon, M. Solomon, 2004, Advances in immunology.

B7-2 (CD86) Controls the Priming of Autoreactive CD4 T Cell Response against Pancreatic Islets1

N. Sarvetnick, L. Sherman, William L. Redmond, 2004, The Journal of Immunology.

Pancreatic Islets Autoreactive CD4 T Cell Response against B7-2 (CD86) Controls the Priming of

N. Sarvetnick, L. Sherman, William L. Redmond, 2004 .

Homeostatic Expansion of T Cells during Immune Insufficiency Generates Autoimmunity

N. Sarvetnick, C. King, A. Ilic, 2004, Cell.

TNF-α Receptor 1 (p55) on Islets Is Necessary for the Expression of LIGHT on Diabetogenic T Cells

N. Sarvetnick, Lieping Chen, A. Ilic, 2001 .

Coxsackieviral-mediated diabetes: induction requires antigen-presenting cells and is accompanied by phagocytosis of beta cells.

N. Sarvetnick, M. Horwitz, A. Ilic, 2004, Clinical immunology.

Coxsackievirus-mediated hyperglycemia is enhanced by reinfection and this occurs independent of T cells.

N. Sarvetnick, M. Horwitz, A. Ilic, 2003, Virology.

Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy.

N. Sarvetnick, I. Verma, T. Kafri, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Vaccination with glutamic acid decarboxylase plasmid DNA protects mice from spontaneous autoimmune diabetes and B7/CD28 costimulation circumvents that protection.

N. Sarvetnick, B. Boehm, W. Karges, 2001, Clinical immunology.

TGF-beta1 alters APC preference, polarizing islet antigen responses toward a Th2 phenotype.

N. Sarvetnick, C. King, Myung-Shik Lee, 1998, Immunity.

Human homologs of two testes-expressed loci on mouse chromosome 17 map to opposite arms of chromosome 6.

P. Goodfellow, H. Zoghbi, L. Silver, 1989, Genomics.

The microbial product lipopolysaccharide confers diabetogenic potential on the T cell repertoire of BDC2.5/NOD mice: implications for the etiology of autoimmune diabetes.

N. Sarvetnick, B. Balasa, K. van Gunst, 2000, Clinical immunology.

Comparing the relative role of perforin/granzyme versus Fas/Fas ligand cytotoxic pathways in CD8+ T cell-mediated insulin-dependent diabetes mellitus.

N. Sarvetnick, L. Sherman, T. Krahl, 1999, Journal of immunology.

Protection from Lethal Coxsackievirus-Induced Pancreatitis by Expression of Gamma Interferon

N. Sarvetnick, M. Horwitz, C. Fine, 1999, Journal of Virology.

Lack of β-catenin in early life induces abnormal glucose homeostasis in mice

N. Sarvetnick, P. Dubus, S. Dabernat, 2009, Diabetologia.

Viruses, cytokines, antigens, and autoimmunity.

N. Sarvetnick, R. Gianani, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Requirements for viral-mediated autoimmune diabetes: beta-cell damage and immune infiltration.

N. Sarvetnick, M. Horwitz, A. Ilic, 2001, Journal of autoimmunity.

Cytokines that regulate autoimmune responses.

N. Sarvetnick, M. Falcone, 1999, Current opinion in immunology.

Increased islet antigen presentation leads to type‐1 diabetes in mice with autoimmune susceptibility

N. Sarvetnick, P. Santamaria, E. Rodríguez, 2004, European journal of immunology.

BMP4 Regulates Pancreatic Progenitor Cell Expansion through Id2*

N. Sarvetnick, S. Dabernat, H. Hua, 2006, Journal of Biological Chemistry.

Treatment of IFN-γ Transgenic Mice With Anti–IFN-γ Reveals the Remodeling Capacity of the Adult Pancreas

N. Sarvetnick, T. Krahl, L. Molony, 1995, Diabetes.

Postnatal anti-interferon-γ treatment prevents pancreatic inflammation in transgenic mice with β-cell expression of interferon-γ

N. Sarvetnick, T. Krahl, L. Wogensen, 1994 .

Functional effects of transgenic expression of cholera toxin in pancreatic beta-cells

J. Sutcliffe, N. Sarvetnick, R. Robertson, 1993, Molecular and Cellular Endocrinology.

CD28⁻ CD8⁺ T cells are significantly reduced and correlate with disease duration in juveniles with type 1 diabetes.

N. Sarvetnick, Danielle N. Yarde, K. Corley, 2014, Human immunology.

IL-4 triggers autoimmune diabetes by increasing self-antigen presentation within the pancreatic Islets.

N. Sarvetnick, E. Rodríguez, T. Krahl, 2001, Clinical immunology.

Etiology of autoimmunity

N. Sarvetnick, 2000, Immunologic research.

IL-10 impacts autoimmune diabetes via a CD8+ T cell pathway circumventing the requirement for CD4+ T and B lymphocytes.

N. Sarvetnick, B. Yeung, A. Good, 1998, Journal of immunology.

Induction of vascular addressins and adhesion molecules in the pancreas of IFN-gamma transgenic mice.

N. Sarvetnick, M. S. Lee, M. Lee, 1994, Journal of immunology.

Pancreatic expression of keratinocyte growth factor leads to differentiation of islet hepatocytes and proliferation of duct cells.

N. Sarvetnick, E. Jones, T. Krahl, 1999, The American journal of pathology.

Transgenic mice expressing IFN-gamma in pancreatic beta-cells are resistant to streptozotocin-induced diabetes.

N. Sarvetnick, M. Arnush, D. Gu, 1995, The American journal of physiology.

This information is current as during Coxsackievirus Infection Complementary Roles in Islet Cell Defense RNA-Dependent Protein Kinase Exert RNase L and Double-Stranded Williams

R. Silverman, N. Sarvetnick, M. Hultcrantz, 2005 .

A transgenic model for studying islet development.

N. Sarvetnick, D. Gu, 1994, Recent progress in hormone research.

Endocrine/Exocrine Intermediate Cells in Streptozotocin‐Treated Ins‐IFN‐γ Transgenic Mice

N. Sarvetnick, M. Arnush, D. Gu, 1997 .

α-Cell Neogenesis in an Animal Model of IDDM

A. Cooke, J. Phillips, N. Sarvetnick, 1997, Diabetes.

Transcription factor expression during pancreatic islet regeneration

N. Sarvetnick, P. Gruss, T. Krahl, 2000, Molecular and Cellular Endocrinology.

Transgenic expression of epidermal growth factor and keratinocyte growth factor in beta-cells results in substantial morphological changes.

N. Sarvetnick, B. Mroczkowski, E. Jones, 1999, The Journal of endocrinology.

Loss of pancreatic islet tolerance induced by β-cell expression of interferon-γ

N. Sarvetnick, D. Liggitt, T. Parslow, 1990, Nature.

Regeneration of pancreatic endocrine cells in interferon-gamma transgenic mice.

N. Sarvetnick, D. Gu, 1992, Advances in experimental medicine and biology.

Pancreatic growth and regeneration

N. Sarvetnick, 1997 .

Leukocyte extravasation into the pancreatic tissue in transgenic mice expressing interleukin 10 in the islets of Langerhans

N. Sarvetnick, Xiaojian Huang, L. Wogensen, 1993, The Journal of experimental medicine.

Frequencies of CD8 and DN MAIT Cells Among Children Diagnosed With Type 1 Diabetes Are Similar to Age-Matched Controls

Lynette M. Smith, N. Sarvetnick, Robert Z. Harms, 2021, Frontiers in Immunology.

STAT4/6-dependent differential regulation of chemokine receptors.

N. Sarvetnick, Soon Ha Kim, K. Gunst, 2006, Clinical immunology.

CD8(+) T cell-mediated spontaneous diabetes in neonatal mice.

H. Mcdevitt, N. Sarvetnick, D. Lo, 1996, Journal of immunology.

Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.

N. Sarvetnick, M. Flodström-Tullberg, P. Secrest, 2003, Diabetes.

Interferon γ (IFN-γ) Is Necessary for the Genesis of Acetylcholine Receptor–induced Clinical Experimental Autoimmune Myasthenia gravis in Mice

P. Christadoss, N. Sarvetnick, L. Bradley, 1997, The Journal of experimental medicine.

IL-21 Limits Peripheral Lymphocyte Numbers through T Cell Homeostatic Mechanisms

N. Sarvetnick, Shrimati Datta, 2008, PloS one.

Epithelial progenitor 1, a novel factor associated with epithelial cell growth and differentiation

N. Sarvetnick, C. U. Lago, A. Kayali, 2010, Endocrine.

Up-Regulation of CD1d Expression Restores the Immunoregulatory Function of NKT Cells and Prevents Autoimmune Diabetes in Nonobese Diabetic Mice1

E. Bonifacio, N. Sarvetnick, F. Sanvito, 2004, The Journal of Immunology.

Necrotizing myopathy induced by overexpression of interferon‐γ in transgenic mice

N. Calcutt, N. Sarvetnick, G. Shelton, 1999 .

Th1 and Th2 Pancreatic Inflammation Differentially Affects Homing of Islet-Reactive CD4 Cells in Nonobese Diabetic Mice 1

N. Sarvetnick, N. Hill, K. van Gunst, 2003, The Journal of Immunology.

Pancreatic IL-4 expression results in islet-reactive Th2 cells that inhibit diabetogenic lymphocytes in the nonobese diabetic mouse.

N. Sarvetnick, J. Davies, B. Balasa, 1999, Journal of immunology.

Growth factors in the regenerating pancreas of gamma-interferon transgenic mice.

N. Sarvetnick, B. Mroczkowski, T. Krahl, 1996, Laboratory investigation; a journal of technical methods and pathology.

MiceIslet-Reactive CD4 Cells in Nonobese Diabetic Differentially Affects Homing of Th1 and Th2 Pancreatic Inflammation

N. Sarvetnick, N. Hill, K. Gunst, 2003 .

IL-10 is necessary and sufficient for autoimmune diabetes in conjunction with NOD MHC homozygosity

N. Sarvetnick, L. Wicker, L. Peterson, 1996, The Journal of experimental medicine.

Loss of pancreatic islet tolerance induced by beta-cell expression of interferon-gamma.

N. Sarvetnick, D. Liggitt, T. Parslow, 1990, Nature.

A mouse chromosome 17 gene encodes a testes-specific transcript with unusual properties

L. Silver, J. Tsai, N. Sarvetnick, 1989, Immunogenetics.

IFN-&ggr; Overexpression Within the Pancreas Is Not Sufficient to Rescue Pax4, Pax6, and Pdx-1 Mutant Mice from Death

N. Sarvetnick, P. Gruss, B. Sosa-Pineda, 2000, Pancreas.

Genetic control of diabetes mellitus

N. Sarvetnick, D. Weatherall, J. Shizuru, 1992, Diabetologia.

Cytokine Transgenic Mice and Autoimmunity

N. Sarvetnick, Myung-Shik Lee, 1996 .

A Mechanism for IL-10-Mediated Diabetes in the Nonobese Diabetic (NOD) Mouse: ICAM-1 Deficiency Blocks Accelerated Diabetes1 2

N. Sarvetnick, A. La Cava, D. Balakrishna, 2000, The Journal of Immunology.

IL-10 deficiency does not inhibit insulitis and accelerates cyclophosphamide-induced diabetes in the nonobese diabetic mouse.

N. Sarvetnick, J. Katz, B. Balasa, 2000, Cellular immunology.

Endocrine/exocrine intermediate cells in streptozotocin-treated Ins-IFN-gamma transgenic mice.

N. Sarvetnick, M. Arnush, D. Gu, 1997, Pancreas.

Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop.

R. Tisch, N. Sarvetnick, L. Wen, 2001, Diabetes.

B7-2 Regulates Survival, Phenotype, and Function of APCs1

N. Sarvetnick, D. Yadav, 2007, The Journal of Immunology.

Function of APCs B7-2 Regulates Survival, Phenotype, and

N. Sarvetnick, D. Yadav, 2022 .

Type 2 Nitric Oxide Synthase Control of the Autoimmune Response by

H. Ljunggren, N. Sarvetnick, Soon Ha Kim, 2001 .

Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses

N. Sarvetnick, R. Ahmed, C. King, 2001, Nature Medicine.

Transgenic expression of interleukin 10 in the pancreas renders resistant mice susceptible to low dose streptozotocin-induced diabetes.

N. Sarvetnick, R. Mueller, M. S. Lee, 1996, Journal of autoimmunity.

Distinct regulation of autoreactive CD4 T cell expansion by interleukin‐4 under conditions of lymphopenia

N. Sarvetnick, A. Stotland, N. Hill, 2007, Journal of leukocyte biology.

Nonobese Diabetic Mice Cells and Prevents Autoimmune Diabetes in the Immunoregulatory Function of NKT Up-Regulation of CD 1 d Expression Restores

E. Bonifacio, N. Sarvetnick, F. Sanvito, 2004 .

Sensitization to self (virus) antigen by in situ expression of murine interferon-gamma.

N. Sarvetnick, M. V. von Herrath, M. Oldstone, 1995, The Journal of clinical investigation.

Islet Tolerance in Humans and Transgenic Mice

N. Sarvetnick, 1993 .

Transgenes in autoimmunity.

N. Sarvetnick, M. S. Lee, M. Lee, 1992, Current opinion in immunology.

Interleukin-4 secretion by the allograft fails to affect the allograft-specific interleukin-4 response in vitro.

N. Sarvetnick, R. Mueller, T. Krahl, 1999, Transplantation.

Autoimmune Myasthenia Gravis the Progression of Antibody-Dependent The Th 2 Cytokine IL-4 Is Not Required for and

P. Christadoss, N. Sarvetnick, C. Deng, 1998 .

FGFR3 Is a Negative Regulator of the Expansion of Pancreatic Epithelial Cells

N. Sarvetnick, A. Kayali, M. Kritzik, 2007, Diabetes.

Increased expression of IL-18 in the serum and islets of type 1 diabetics.

N. Sarvetnick, Robert Z. Harms, Zachary P Guinn, 2015, Molecular immunology.

Pancreatic Expression o f Interleukin-4 Abrogates Insulitis and

N. Sarvetnick, R. Mueller, T. Krahl, 2003 .

Islet-Specific Expression of IL-10 Promotes Diabetes in Nonobese Diabetic Mice Independent of Fas, Perforin, TNF Receptor-1, and TNF Receptor-2 Molecules1

N. Sarvetnick, T. Hanafusa, D. Balakrishna, 2000, The Journal of Immunology.

Receptor-1 , and TNF Receptor-2 Molecules Independent of Fas , Perforin , TNF Diabetes in Nonobese Diabetic Mice Islet-Specific Expression of IL-10 Promotes

N. Sarvetnick, T. Hanafusa, D. Balakrishna, 2000 .

Insulin-Dependent Diabetes Mellitus T Cell-Mediated + Cytotoxic Pathways in CD 8 Perforin / Granzyme Versus Fas / Fas Ligand Comparing the Relative Role of Ko ,

N. Sarvetnick, L. Sherman, T. Krahl, 1999 .

Altered availability of PD-1/PD ligands is associated with the failure to control autoimmunity in NOD mice.

N. Sarvetnick, M. Azuma, H. Yagita, 2009, Cellular immunology.

Costimulation and pancreatic autoimmunity: the PD-1/PD-L conundrum.

N. Sarvetnick, D. Yadav, 2006, The review of diabetic studies : RDS.

B7-1 mediated costimulation regulates pancreatic autoimmunity.

N. Sarvetnick, M. Azuma, C. Fine, 2007, Molecular immunology.

Peptide specific amelioration of T cell mediated pathogenesis in murine type 1 diabetes.

N. Sarvetnick, J. Bluestone, C. Pinilla, 2004, Clinical immunology.

Is pathogenic humoral autoimmunity a Th1 response? Lessons from (for) myasthenia gravis.

N. Sarvetnick, B. Balasa, Nora Sarvetnick, 2000, Immunology today.

Fetal exposure to interferon-gamma leads to induction of antigen-presenting molecules and leukocyte recruitment.

N. Sarvetnick, M. S. Lee, M. Lee, 1997, Autoimmunity.

Insulin-dependent diabetes mellitus induced in transgenic mice by ectopic expression of class II MHC and interferon-gamma

N. Sarvetnick, D. Liggitt, S. L. Pitts, 1988, Cell.

Cholecystokinin expression in the developing and regenerating pancreas and intestine.

N. Sarvetnick, T. Krahl, S. Pakala, 2001, The Journal of endocrinology.

TLR signaling controls lethal encephalitis in WNV-infected brain

N. Sarvetnick, H. Fox, M. Marcondes, 2014, Brain Research.

Transgenic/knockout mice--tools to study autoimmunity.

N. Sarvetnick, R. Mueller, 1995, Current opinion in immunology.

Immunomodulation of the Anti-Islet CD8 T Cell Response by B7-2

N. Sarvetnick, D. Yadav, 2007, Journal of Clinical Immunology.

Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass.

N. Sarvetnick, Brian P. Boerner, Shakeel U. R. Mir, 2015, Molecular endocrinology.

Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice.

N. Sarvetnick, D Gu, N Sarvetnick, 1993, Development.

FGFR3 contributes to intestinal crypt cell growth arrest

N. Sarvetnick, S. Arnaud-Dabernat, D. Yadav, 2008, Journal of cellular physiology.

Interferon-gamma protects against herpes simplex virus type 1-mediated neuronal death.

M. Buchmeier, John Calvin Reed, N. Sarvetnick, 1997, Virology.

CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse

N. Sarvetnick, B. Balasa, Michelle F Solomon, 2010, Autoimmunity.

Local production of IFN-gamma abrogates the intraocular immune privilege in transgenic mice and prevents the induction of ACAID.

N. Sarvetnick, K. Geiger, 1994, Journal of immunology.

From the 1 st International NOD Mouse T-Cell Workshop and the Follow-Up Mini-Workshop

R. Tisch, N. Sarvetnick, L. Wen, 2001 .

Differential impact of T cell repertoire diversity in diabetes-prone or -resistant IL-10 transgenic mice.

N. Sarvetnick, J. Lee, B. Balasa, 1999, Cellular immunology.

TGF-β superfamily member Nodal stimulates human β-cell proliferation while maintaining cellular viability.

N. Sarvetnick, Brian P. Boerner, N. George, 2013, Endocrinology.

Beta-cell specific expression of suppressor of cytokine signaling-1 (SOCS-1) delays islet allograft rejection by down-regulating Interferon Regulatory Factor-1 (IRF-1) signaling.

N. Sarvetnick, M. Flodström-Tullberg, M. Solomon, 2011, Transplant immunology.

Expression of Id1 in adult, regenerating and developing pancreas

N. Sarvetnick, H. Hua, 2007, Endocrine.

Differences in Suppressor of Cytokine Signaling-1 (SOCS-1) Expressing Islet Allograft Destruction in Normal BALB/c and Spontaneously-Diabetic NOD Recipient Mice

N. Sarvetnick, M. Flodström-Tullberg, M. Solomon, 2005, Transplantation.

Methods for Detection of Apoptosis in the CNS

F. Bloom, N. Sarvetnick, K. Geiger, 1997 .

T cell homeostasis in tolerance and immunity

N. Sarvetnick, A. Marleau, 2005, Journal of leukocyte biology.

Autoimmunity a bias from tolerance to immunity.

N. Sarvetnick, P. Ohashi, 1997, Current opinion in immunology.

Predominant end-products of prophage Mu DNA transposition during the lytic cycle are replicon fusions.

N. Sarvetnick, R. Harshey, G. Chaconas, 1981, Journal of molecular biology.

Short communication Protective effects of interferon-gamma in intraocular herpes simplex type I infection do not depend on major histocompatibility complex class I or class I1 expression

N. Sarvetnick, K. Geiger, C. Baugh, 1995 .

Protective effects of interferon-gamma in intraocular herpes simplex type 1 infection do not depend on major histocompatibility complex class I or class II expression.

N. Sarvetnick, K. Geiger, C. Baugh, 1995, Journal of neurovirology.

The Natural Killer Cell – Friend or Foe in Autoimmune Disease?

F. Shi, H. Ljunggren, N. Sarvetnick, 2002, Scandinavian journal of immunology.

Ectopic expression of gamma interferon in the eye protects transgenic mice from intraocular herpes simplex virus type 1 infections

N. Sarvetnick, K. Geiger, E. Howes, 1994, Journal of virology.

Transgenic mice expressing IFN-gamma in the retina develop inflammation of the eye and photoreceptor loss.

N. Sarvetnick, K. Geiger, G. Travis, 1994, Investigative ophthalmology & visual science.

Viruses, host responses, and autoimmunity

N. Sarvetnick, M. Horwitz, 1999, Immunological reviews.

Interferon-γ Protects against Herpes Simplex Virus Type 1-Mediated Neuronal Death

M. Buchmeier, John Calvin Reed, N. Sarvetnick, 1997 .

Altered CD161bright CD8+ Mucosal Associated Invariant T (MAIT)-Like Cell Dynamics and Increased Differentiation States among Juvenile Type 1 Diabetics

N. Sarvetnick, Robert Z. Harms, K. Corley, 2015, PloS one.

Control of the Autoimmune Response by Type 2 Nitric Oxide Synthase1 2

F. Shi, H. Ljunggren, N. Sarvetnick, 2001, The Journal of Immunology.

Cytokine-mediated survival from lethal herpes simplex virus infection: role of programmed neuronal death.

F. Bloom, John Calvin Reed, N. Sarvetnick, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Production of interleukin 10 by islet cells accelerates immune-mediated destruction of beta cells in nonobese diabetic mice

N. Sarvetnick, L. Wogensen, M. S. Lee, 1994, The Journal of experimental medicine.

Pancreatic IL-10 induces diabetes in NOD.B6 Idd3 Idd10 mice.

N. Sarvetnick, L. Wicker, L. Peterson, 1997, Autoimmunity.

The paradoxical effects of interleukin 10 in the immunoregulation of autoimmune diabetes.

N. Sarvetnick, B. Balasa, 1996, Journal of autoimmunity.

Differential IL-21 signaling in APCs leads to disparate Th17 differentiation in diabetes-susceptible NOD and diabetes-resistant NOD.Idd3 mice.

Jenna M. Sullivan, David H. Lee, N. Sarvetnick, 2011, The Journal of clinical investigation.

Nonhomologous pairing in mice heterozygous for a t haplotype can produce recombinant chromosomes with duplications and deletions.

R. Elliott, L. Silver, N. Sarvetnick, 1986, Genetics.

Growth factor-induced signaling of the pancreatic epithelium.

N. Sarvetnick, S. Dabernat, A. Kayali, 2005, The Journal of endocrinology.

Development of cell markers for the identification and expansion of islet progenitor cells

N. Sarvetnick, You-qing Zhang, 2003, Diabetes/metabolism research and reviews.

Identification of MHC Class II-Restricted Peptide Ligands, Including a Glutamic Acid Decarboxylase 65 Sequence, that Stimulate Diabetogenic T Cells from Transgenic BDC2.5 Nonobese Diabetic Mice1

Clemencia Pinilla, Lee Tucker, N. Sarvetnick, 2001, The Journal of Immunology.

Mechanism underlying counterregulation of autoimmune diabetes by IL-4.

N. Sarvetnick, L. Bradley, R. Mueller, 1997, Immunity.

The effect of local production of cytokines in the pathogenesis of insulin-dependent diabetes mellitus.

N. Sarvetnick, M. Falcone, 1999, Clinical immunology.

Pancreatic islet production of murine interleukin-10 does not inhibit immune-mediated tissue destruction.

N. Sarvetnick, M. Oldstone, J. Shizuru, 1994, The Journal of clinical investigation.

The stromal cell–derived factor-1α/CXCR4 ligand–receptor axis is critical for progenitor survival and migration in the pancreas

N. Sarvetnick, A. Kayali, I. Campbell, 2003, The Journal of cell biology.

Peptides from common viral and bacterial pathogens can efficiently activate diabetogenic T-cells.

N. Sarvetnick, C. Pinilla, V. Judkowski, 2004, Diabetes.

Terminal Deoxynucleotidyltransferase Deficiency Decreases Autoimmune Disease in Diabetes-Prone Nonobese Diabetic Mice and Lupus-Prone MRL-Faslpr Mice1

A. Feeney, N. Sarvetnick, D. Kono, 2004, The Journal of Immunology.

Strong attraction may be dangerous: parameters for the development of long term commitment.

N. Sarvetnick, C. Pinilla, P. Sanna, 2004, Molecular immunology.

Current understanding of the role of gut dysbiosis in type 1 diabetes

N. Sarvetnick, Ahmed M Abdellatif, 2019, Journal of diabetes.

H-2D End Confers Dominant Protection from IL-10-Mediated Acceleration of Autoimmune Diabetes in the Nonobese Diabetic Mouse1

N. Sarvetnick, A. La Cava, A. Good, 2001, The Journal of Immunology.

Coordinated Induction of Antimicrobial Response Factors in Systemic Lupus Erythematosus

N. Sarvetnick, J. Buckner, Robert Z. Harms, 2019, Front. Immunol..

Type 1 diabetes: role of intestinal microbiome in humans and mice

N. Sarvetnick, Brian P. Boerner, 2011, Annals of the New York Academy of Sciences.

Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expression.

N. Sarvetnick, I. Verma, E. Schwarz, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Islet-specific Th1, but not Th2, cells secrete multiple chemokines and promote rapid induction of autoimmune diabetes.

N. Sarvetnick, I. Campbell, L. Bradley, 1999, Journal of immunology.

CCR4-bearing T cells participate in autoimmune diabetes.

N. Sarvetnick, H. Fox, Soon Ha Kim, 2002, The Journal of clinical investigation.

A key role for ICAM-1 in generating effector cells mediating inflammatory responses

P. A. Peterson, L. Karlsson, N. Sarvetnick, 2001, Nature Immunology.

Induction of Autoimmune Diabetes Multiple Chemokines and Promote Rapid Islet-Specific Th 1 , But Not Th 2 , Cells Secrete

N. Sarvetnick, I. Campbell, L. Bradley, 1999 .

Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes

Lynette M. Smith, N. Sarvetnick, P. Gottlieb, 2018, Front. Immunol..

Mechanism of bacteriophage Mu DNA transposition.

N. Sarvetnick, R. Harshey, G. Chaconas, 1981, Cold Spring Harbor symposia on quantitative biology.

Expression of ErbB receptors during pancreatic islet development and regrowth.

N. Sarvetnick, T. Krahl, M. Kritzik, 2000, The Journal of endocrinology.

Pancreatic expression of interferon-γ protects mice from lethal coxsackievirus B3 infection and subsequent myocarditis

N. Sarvetnick, M. Horwitz, A. Ilic, 2000, Nature Medicine.

Transforming growth factor-beta fails to inhibit allograft rejection or virus-induced autoimmune diabetes in transgenic mice.

N. Sarvetnick, M. V. von Herrath, M. Oldstone, 1996, Transplantation.

IL-18 Directs Autoreactive T Cells and Promotes Autodestruction in the Central Nervous System Via Induction of IFN-γ by NK Cells1

S. Akira, F. Shi, H. Ljunggren, 2000, The Journal of Immunology.

The Role of NK Cells and NK Cell Receptors inAutoimmune Disease

N. Sarvetnick, H. Jie, 2004, Autoimmunity.

Transforming growth factor-beta inhibits coxsackievirus-mediated autoimmune myocarditis.

N. Sarvetnick, M. Horwitz, A. Ilic, 2006, Viral immunology.

Transgenic models of diabetes.

N. Sarvetnick, 1990, Current opinion in immunology.

Anti-human Interleukin(IL)-4 Clone 8D4-8 Cross-Reacts With Myosin-9 Associated With Apoptotic Cells and Should Not Be Used for Flow Cytometry Applications Querying IL-4 Expression

N. Sarvetnick, Vikas Kumar, Robert Z. Harms, 2019, Front. Cell Dev. Biol..

Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse

F. Shi, N. Sarvetnick, J. Strominger, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Induction of antigen specific peripheral humoral tolerance to cardiac myosin does not prevent CB3-mediated autoimmune myocarditis.

N. Sarvetnick, M. Horwitz, A. Ilic, 2005, Journal of autoimmunity.

Cytokines and autoimmunity: redundancy defines their complex nature.

N. Sarvetnick, D. Yadav, 2003, Current opinion in immunology.

A Defect in Interleukin 12–Induced Activation and Interferon γ Secretion of Peripheral Natural Killer T Cells in Nonobese Diabetic Mice Suggests New Pathogenic Mechanisms for Insulin-Dependent Diabetes Mellitus

N. Sarvetnick, E. Rodríguez, M. Falcone, 1999, The Journal of experimental medicine.

Methamphetamine Administration Targets Multiple Immune Subsets and Induces Phenotypic Alterations Suggestive of Immunosuppression

N. Sarvetnick, H. Fox, B. Morsey, 2012, PloS one.

Granulocyte macrophage‐colony stimulating factor (GM‐CSF) recruits immune cells to the pancreas and delays STZ‐induced diabetes

Troy Krahl, N. Sarvetnick, T. Krahl, 2002, The Journal of pathology.

Leptin accelerates autoimmune diabetes in female NOD mice.

N. Sarvetnick, R. Lechler, A. La Cava, 2002, Diabetes.

CD4+ CD45RB low-density cells from untreated mice prevent acute allograft rejection.

N. Sarvetnick, J. Trotter, T. Krahl, 1999, Journal of immunology.

Cytokines and IDDM: implications for etiology and therapy.

N. Sarvetnick, B. Balasa, 1998, Drug news & perspectives.

Upregulation of activin signaling in experimental colitis.

N. Sarvetnick, K. Barrett, B. Jung, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Target cell defense prevents the development of diabetes after viral infection

N. Sarvetnick, A. Yoshimura, D. Balakrishna, 2002, Nature Immunology.

Human Islet Response to Selected Type 1 Diabetes-Associated Bacteria: A Transcriptome-Based Study

N. Sarvetnick, Robert Z. Harms, Ahmed M Abdellatif, 2019, Front. Immunol..

Tissue-specific expression of interleukin-4 induces extracellular matrix accumulation and extravasation of B cells.

N. Sarvetnick, R. Mueller, T. Krahl, 1997, Laboratory investigation; a journal of technical methods and pathology.

Heightened Levels of Antimicrobial Response Factors in Patients With Rheumatoid Arthritis

N. Sarvetnick, V. Holers, T. Mikuls, 2020, Frontiers in Immunology.

Hippo Signaling Regulates Pancreas Development through Inactivation of Yap

N. Sarvetnick, Randy L. Johnson, Nicholas M. George, 2012, Molecular and Cellular Biology.

The Th2 cytokine IL-4 is not required for the progression of antibody-dependent autoimmune myasthenia gravis.

P. Christadoss, N. Sarvetnick, J. Lee, 1998, Journal of immunology.

The Incidence of Type-1 Diabetes in NOD Mice Is Modulated by Restricted Flora Not Germ-Free Conditions

N. Sarvetnick, C. King, 2011, PloS one.

Interferon γ (IFN-γ) Is Necessary for the Genesis of Acetylcholine Receptor–induced Clinical Experimental Autoimmune Myasthenia gravis in Mice

P. Christadoss, N. Sarvetnick, L. Bradley, 1997, The Journal of experimental medicine.

alpha-Cell neogenesis in an animal model of IDDM.

A. Cooke, J. Phillips, N. Sarvetnick, 1997, Diabetes.

IL-18 is required for self-reactive T cell expansion in NOD mice.

N. Sarvetnick, A. Marleau, 2011, Journal of autoimmunity.

Autoimmunity mediated by innate immune effector cells

F. Shi, H. Ljunggren, N. Sarvetnick, 2001 .

Identification and expansion of pancreatic stem/progenitor cells

N. Sarvetnick, M. Kritzik, You-qing Zhang, 2005, Journal of cellular and molecular medicine.

ID2 promotes the expansion and survival of growth-arrested pancreatic beta cells

N. Sarvetnick, H. Hua, 2007, Endocrine.

IL-4 expression by grafts from transgenic mice fails to prevent allograft rejection.

N. Sarvetnick, R. Mueller, T. Krahl, 1997, Journal of immunology.

Under control of the Ren-1c promoter, locally produced transforming growth factor-beta1 induces accumulation of glomerular extracellular matrix in transgenic mice.

N. Sarvetnick, C. Nielsen, A. Nielsen, 1999, Diabetes.

WS6 induces both alpha and beta cell proliferation without affecting differentiation or viability.

N. Sarvetnick, Brian P. Boerner, Shakeel U. R. Mir, 2015, Endocrine journal.

Increasing the chemical potential of the germ-line antibody repertoire.

R. Lerner, N. Sarvetnick, P. Schultz, 1993, Proceedings of the National Academy of Sciences of the United States of America.

IFN-gamma, IGIF, and IDDM.

N. Sarvetnick, 1997, The Journal of clinical investigation.

CD 4 1 CD 45 RB Low-Density Cells from Untreated Mice Prevent Acute Allograft Rejection 1

N. Sarvetnick, J. Trotter, T. Krahl, 1999 .