C. Bremer

发表

Fluorescence molecular tomography resolves protease activity in vivo

R. Weissleder, C. Tung, V. Ntziachristos, 2002, Nature Medicine.

Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging

R. Weissleder, V. Ntziachristos, C. Bremer, 2002, European Radiology.

MR and optical approaches to molecular imaging

W. Heindel, W. Heindel, C. Bremer, 2005, Abdominal Imaging.

In vivo imaging of gene expression:.

R Weissleder, R. Weissleder, C. Bremer, 2001, Academic radiology.

R2 and R2* mapping for sensing cell-bound superparamagnetic nanoparticles: in vitro and murine in vivo testing.

Tobias Schaeffter, Thorsten Persigehl, Hannes Dahnke, 2007, Radiology.

Imaging of differential protease expression in breast cancers for detection of aggressive tumor phenotypes.

R. Weissleder, C. Tung, C. Bremer, 2002, Radiology.

Optical Imaging of Spontaneous Breast Tumors Using Protease Sensing ‘Smart’ Optical Probes

R. Weissleder, W. Heindel, V. Ntziachristos, 2005, Investigative radiology.

Optical-based molecular imaging: contrast agents and potential medical applications

R. Weissleder, V. Ntziachristos, C. Bremer, 2003, European Radiology.

First‐pass and equilibrium‐MRA of the aortoiliac region with a superparamagnetic iron oxide blood pool MR contrast agent (SH U 555 C): results of a human pilot study

W. Heindel, C. Bremer, T. Allkemper, 2004, NMR in biomedicine.

Optical imaging of matrix metalloproteinase-2 activity in tumors: feasibility study in a mouse model.

R Weissleder, R. Weissleder, C. Tung, 2001, Radiology.

In vivo molecular target assessment of matrix metalloproteinase inhibition

Ralph Weissleder, Christoph Bremer, R. Weissleder, 2001, Nature Medicine.

Fluorescence Imaging of Breast Tumors and Gastrointestinal Cancer.

C. Bremer, D. Grosenick, 2020, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Near-Infrared Imaging of the Breast Using Omocianine as a Fluorescent Dye: Results of a Placebo-Controlled, Clinical, Multicenter Trial

Thorsten Persigehl, Steven L. Ponder, Felix Diekmann, 2011, Investigative radiology.

Hazardous situation in the MR bore: induction in ECG leads causes fire

Walter Heindel, Bernd Tombach, Roman Fischbach, 2003, European Radiology.

Diagnostic Optical Imaging of Breast Cancer: From Animal Models to First-in-Men Studies

C. Bremer, T. Persigehl, M. Eisenblätter, 2011 .

Accuracy of non-enhanced MRI to monitor histological lesion size during laser-induced interstitial thermotherapy

Peter Reimer, Christoph Bremer, C. Bremer, 2002, European Radiology.

Optical In Vivo Imaging of the Alarmin S100A9 in Tumor Lesions Allows for Estimation of the Individual Malignant Potential by Evaluation of Tumor–Host Cell Interaction

W. Heindel, C. Bremer, T. Vogl, 2015, The Journal of Nuclear Medicine.

Index terms: Iron

C. Bremer, T. Allkemper, P. Reimer, 2022 .

4.23 – External Transdermal Procedures

C. Bremer, M. Eisenblätter, 2014 .

High‐dose Gd‐DTPA vs. Bis‐Gd‐mesoporphyrin for monitoring laser‐induced tissue necrosis

C. Bremer, P. Reimer, B. Tombach, 2005, Journal of magnetic resonance imaging : JMRI.

Renal tolerance of a neutral gadolinium chelate (gadobutrol) in patients with chronic renal failure: results of a randomized study.

W. Heindel, C. Bremer, P. Reimer, 2001, Radiology.

efficiency by positron emission tomography mapping of disease activity, prediction and monitoring of treatment Clinical molecular imaging in intestinal graft-versus-host disease:

O. Schober, C. Bremer, C. Poremba, 2013 .

Clinical molecular imaging in intestinal graft-versus-host disease: mapping of disease activity, prediction, and monitoring of treatment efficiency by positron emission tomography.

O. Schober, C. Franzius, C. Bremer, 2008, Blood.

Effect of Primary Tumor Side on Survival Outcomes in Untreated Patients With Metastatic Colorectal Cancer When Selective Internal Radiation Therapy Is Added to Chemotherapy: Combined Analysis of Two Randomized Controlled Studies

V. Gebski, P. Gibbs, F. Lammert, 2018, Clinical colorectal cancer.

Assessment of reperfusion injury by means of MR contrast agents in rat liver

E. Rummeny, C. Bremer, T. Allkemper, 1997, Journal of magnetic resonance imaging : JMRI.

Concurrent MR blood volume and vessel size estimation in tumors by robust and simultaneous ΔR2 and ΔR2* quantification

W. Heindel, C. Bremer, J. Sénégas, 2011, Magnetic resonance in medicine.

Antiangiogenic Tumor Treatment: Early Noninvasive MonitoringwithUSPIO-enhancedMR

W. Heindel, C. Bremer, H. Kooijman, 2007 .

Pharmacokinetics of 1M gadobutrol in patients with chronic renal failure.

W. Heindel, C. Bremer, P. Reimer, 2000, Investigative radiology.

Using highly concentrated gadobutrol as an MR contrast agent in patients also requiring hemodialysis: safety and dialysability.

W. Heindel, C. Bremer, P. Reimer, 2002, AJR. American journal of roentgenology.

Prediction of Antiangiogenic Treatment Efficacy by Iron Oxide Enhanced Parametric Magnetic Resonance Imaging

W. Heindel, C. Bremer, W. Berdel, 2007, Investigative radiology.

Preliminary clinical experience with laser‐induced interstitial thermotherapy in patients with hepatocellular carcinoma

E. Rummeny, C. Bremer, T. Allkemper, 1998, Journal of magnetic resonance imaging : JMRI.

Gadofosveset-enhanced MRI as simple surrogate parameter for real-time evaluation of the initial tumour vessel infarction by retargeted tissue factor tTF-NGR

W. Heindel, C. Bremer, W. Berdel, 2018, Oncology letters.

Tissue-factor fusion proteins induce occlusion of tumor vessels.

W. Heindel, C. Bremer, W. Berdel, 2010, Thrombosis research.

Detection of dysplastic intestinal adenomas using enzyme-sensing molecular beacons in mice.

Ralph Weissleder, Bonnie F. Sloane, Katharina Marten, 2002, Gastroenterology.

Monitoring of Bevacizumab-Induced Antiangiogenic Treatment Effects By “Steady State” Ultrasmall Superparamagnetic Iron Oxide Particles Magnetic Resonance Imaging Using Robust Multiecho &Dgr;R2* Relaxometry

W. Heindel, C. Bremer, T. Persigehl, 2011, Investigative radiology.

In Vivo Fluorescence-mediated Tomography for Quantification of Urokinase Receptor-dependent Leukocyte Trafficking in Inflammation

C. Bremer, R. Hildebrand, G. Theilmeier, 2010, Anesthesiology.

Labeling of Anti-MUC-1 Binding Single Chain Fv Fragments to Surface Modified Upconversion Nanoparticles for an Initial in Vivo Molecular Imaging Proof of Principle Approach

C. Bremer, M. Haase, T. Thepen, 2012, International journal of molecular sciences.

In Vivo Imaging of Plaque Stabilization by Statins

C. Bremer, G. Theilmeier, T. Frenzel, 2013 .

Oligomerization of Paramagnetic Substrates Result in Signal Amplification and Can be Used for MR Imaging of Molecular Targets

Alexander Petrovsky, Ralph Weissleder, Christoph Bremer, 2002, Molecular imaging.

Steady-state blood volume measurements in experimental tumors with different angiogenic burdens a study in mice.

Vasilis Ntziachristos, Alexander Petrovsky, Ralph Weissleder, 2003, Radiology.

Assessment of bone marrow angiogenesis in patients with acute myeloid leukemia by using contrast-enhanced MR imaging with clinically approved iron oxides: initial experience.

W. Heindel, C. Bremer, H. Kooijman, 2007, Radiology.

Analysis of the contrast agent Magnevist and its transmetalation products in blood plasma by capillary electrophoresis/electrospray ionization time-of-flight mass spectrometry.

C. Bremer, G. Wiesmüller, U. Karst, 2009, Analytical chemistry.

A fluorescent photoprobe for the imaging of endothelin receptors.

W. Heindel, O. Schober, C. Bremer, 2007, Bioconjugate chemistry.

PET-compatible endothelin receptor radioligands: synthesis and first in vitro and in vivo studies.

O. Schober, C. Bremer, M. Schäfers, 2009, Bioorganic & medicinal chemistry.

Infarction of tumor vessels by NGR-peptide-directed targeting of tissue factor: experimental results and first-in-man experience.

Walter Heindel, Thorsten Persigehl, Torsten Kessler, 2009, Blood.

[Progress in optical imaging].

R. Weissleder, C. Tung, V. Ntziachristos, 2001, Der Radiologe.

Endothelin-A-receptor antagonism with atrasentan exhibits limited activity on the KU-19-19 bladder cancer cell line in a mouse model

C. Bremer, L. Hertle, C. Bolenz, 2009, Journal of Cancer Research and Clinical Oncology.

Acceleration of Coronal Mass Ejection Plasma in the Low Corona as Measured by the Citizen CATE Experiment

David Anderson, Jennifer J. Birriel, Karan Davis, 2019, Publications of the Astronomical Society of the Pacific.

Antiangiogenic tumor treatment: early noninvasive monitoring with USPIO-enhanced MR imaging in mice.

Walter Heindel, Thorsten Persigehl, Torsten Kessler, 2007, Radiology.

Alarmin S100A8/S100A9 as a biomarker for molecular imaging of local inflammatory activity

C. Bremer, M. Schäfers, T. Vogl, 2014, Nature Communications.

Cell tagging with clinically approved iron oxides: feasibility and effect of lipofection, particle size, and surface coating on labeling efficiency.

W. Heindel, W. Schwindt, C. Bremer, 2005, Radiology.

Structural cartilage damage attracts circulating rheumatoid arthritis synovial fibroblasts into affected joints

C. Bremer, H. Pavenstädt, T. Pap, 2017, Arthritis Research & Therapy.

Ex Vivo Evaluation of Novel Miniaturized Laser-Induced Interstitial Thermotherapy Applicators for Effective Small-Volume Tissue Ablation

C. Bremer, A. Roggan, P. Reimer, 2001, Investigative radiology.

Tumor blood volume determination by using susceptibility-corrected DeltaR2* multiecho MR.

W. Heindel, C. Bremer, T. Persigehl, 2010, Radiology.

Synthesis and evaluation of a novel fluorescent photoprobe for imaging matrix metalloproteinases.

W. Heindel, C. Bremer, M. Schäfers, 2008, Bioconjugate chemistry.

Detection of lymph node metastases by contrast‐enhanced MRI in an experimental model

R. Weissleder, L. Josephson, C. Bremer, 2002, Magnetic resonance in medicine.

Chemotherapy in metastatic malignant triton tumor: report on two cases.

C. Bremer, L. Stegger, W. Berdel, 2007, Oncology reports.

Target-Specific Imaging of Cathepsin and S100A8/A9 Reflects Specific Features of Malignancy and Enables Estimation of Tumor Malignancy

W. Heindel, C. Bremer, M. Wildgruber, 2019, Molecular Imaging and Biology.

Optical imaging of breast tumors with protease-activatable fluorescent probes: A prognostic tool for breast cancer?

R. Weissleder, C. Tung, C. Bremer, 2000 .

In Vivo Optical Imaging of Cellular Inflammatory Response in Granuloma Formation Using Fluorescence-Labeled Macrophages

W. Heindel, C. Bremer, J. Roth, 2009, Journal of Nuclear Medicine.

The Role of Nuclear Medicine in Relation to Alternative Modalities

R. Weissleder, C. Bremer, 2003 .

Highly shifted proton MR imaging: cell tracking by using direct detection of paramagnetic compounds.

C. Bremer, U. Karst, S. Aime, 2014, Radiology.

imaging: Cell Tracking by Using Direct Detection of Paramagnetic Compounds 1

C. Bremer, U. Karst, S. Aime, 2014 .

Cine and tagged magnetic resonance imaging in short-term stunned versus necrotic myocardium

Walter Heindel, Bernd Tombach, Peter Reimer, 2005, The International Journal of Cardiovascular Imaging.

Assessment of endothelin-A receptor expression in subcutaneous and orthotopic thyroid carcinoma xenografts in vivo employing optical imaging methods.

O. Schober, C. Bremer, M. Schäfers, 2012, Endocrinology.

Imaging of proteases for tumor detection and differentiation.

C. Bremer, 2005, Ernst Schering Research Foundation workshop.

Feasibility of Functional Cardiac MR Imaging in Mice Using A Clinical 3 Tesla Whole Body Scanner

Walter Heindel, David Maintz, Jörg Stypmann, 2009, Investigative radiology.

First-line selective internal radiotherapy plus chemotherapy versus chemotherapy alone in patients with liver metastases from colorectal cancer (FOXFIRE, SIRFLOX, and FOXFIRE-Global): a combined analysis of three multicentre, randomised, phase 3 trials

V. Gebski, P. Gibbs, F. Lammert, 2017, The Lancet. Oncology.

In Vivo Fluorescence-mediated Tomography Imaging Demonstrates Atorvastatin-mediated Reduction of Lesion Macrophages in ApoE-/- Mice

C. Bremer, G. Theilmeier, T. Frenzel, 2013, Anesthesiology.

Design and synthesis of small-molecule fluorescent photoprobes targeted to aminopeptdase N (APN/CD13) for optical imaging of angiogenesis.

C. Bremer, M. Schäfers, C. Höltke, 2013, Bioconjugate chemistry.

In vivo optical imaging of CD13/APN-expression in tumor xenografts.

W. Heindel, C. Bremer, M. Schäfers, 2008, Journal of biomedical optics.

Performance of a new fluorescence-labeled MMP inhibitor to image tumor MMP activity in vivo in comparison to an MMP-activatable probe.

C. Bremer, M. Schäfers, A. Faust, 2013, Contrast media & molecular imaging.

Contrast-enhanced blood-pool MR angiography with optimized iron oxides: effect of size and dose on vascular contrast enhancement in rabbits.

C. Bremer, T. Allkemper, L. Matuszewski, 2002, Radiology.

Optimizing the bioavailability of small molecular optical imaging probes by conjugation to an albumin affinity tag.

C. Bremer, C. Höltke, A. Hahnenkamp, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Cell tracking with optical imaging

Bernd J. Pichler, Heike E. Daldrup-Link, Christoph Bremer, 2008, European Radiology.

Oligomerization of paramagnetic substrates result in signal amplification and can be used for MR imaging of molecular targets.

R. Weissleder, C. Bremer, A. Bogdanov, 2002 .

Biodistribution of a Nonpeptidic Fluorescent Endothelin a Receptor Imaging Probe

W. Heindel, O. Schober, C. Bremer, 2009, Molecular imaging.

Synthesis, in vitro pharmacology and biodistribution studies of new PD 156707-derived ET(A) receptor radioligands.

O. Schober, C. Bremer, M. Schäfers, 2006, Bioorganic & medicinal chemistry.

Claudin-4-targeted optical imaging detects pancreatic cancer and its precursor lesions

D. Tuveson, C. Bremer, T. Gress, 2012, Gut.

Non-invasive monitoring of tumor-vessel infarction by retargeted truncated tissue factor tTF–NGR using multi-modal imaging

W. Heindel, C. Bremer, M. Schäfers, 2013, Angiogenesis.

Inhibition of Tumor Growth by RGD Peptide–Directed Delivery of Truncated Tissue Factor to the Tumor Vasculature

Thorsten Persigehl, Torsten Kessler, Christoph Bremer, 2005, Clinical Cancer Research.

Non-invasive monitoring of tumor-vessel infarction by retargeted truncated tissue factor tTF–NGR using multi-modal imaging

W. Heindel, C. Bremer, M. Schäfers, 2013, Angiogenesis.

Fluorescent non-peptidic RGD mimetics with high selectivity for αVβ3 vs αIIbβ3 integrin receptor: novel probes for in vivo optical imaging.

Michael Schäfers, Christoph Bremer, C. Bremer, 2014, Journal of medicinal chemistry.

Synthesis and evaluation of a novel hydroxamate based fluorescent photoprobe for imaging of matrix metalloproteinases.

W. Heindel, O. Schober, C. Bremer, 2009, Bioconjugate chemistry.

Optical techniques for the molecular imaging of angiogenesis

Thorsten Persigehl, Christoph Bremer, C. Bremer, 2010, European Journal of Nuclear Medicine and Molecular Imaging.

In vivo imaging of integrin ανβ3 expression using fluorescence-mediated tomography

W. Heindel, C. Bremer, M. Schäfers, 2007, European Journal of Nuclear Medicine and Molecular Imaging.

Near-infrared fluorescence imaging of lymph nodes using a new enzyme sensing activatable macromolecular optical probe

Christoph Bremer, C. Bremer, P. Wunderbaldinger, 2003, European Radiology.

Does a higher concentration of gadolinium chelates improve first‐pass cardiac signal changes?

C. Bremer, P. Reimer, A. Mühler, 1999, Journal of magnetic resonance imaging : JMRI.

Vessel Size Imaging (VSI) by Robust Magnetic Resonance (MR) Relaxometry: MR-VSI of Solid Tumors in Correlation with Immunohistology and Intravital Microscopy

L. Schwartz, W. Heindel, C. Bremer, 2013, Molecular imaging.

In Vivo Tomographic Imaging of Near-Infrared Fluorescent Probes

Vasilis Ntziachristos, Jorge Ripoll, Ralph Weissleder, 2002 .

In vivo tomographic imaging of near-infrared fluorescent probes.

Vasilis Ntziachristos, Jorge Ripoll, Ralph Weissleder, 2002, Molecular imaging.

In vivo monitoring of angiogenesis during tendon repair: a novel MRI-based technique in a rat patellar tendon model

C. Bremer, T. Persigehl, V. Vieth, 2015, Knee Surgery, Sports Traumatology, Arthroscopy.

Imaging cathepsin B up-regulation in HT-1080 tumor models using fluorescence-mediated molecular tomography (FMT).

R. Weissleder, C. Tung, V. Ntziachristos, 2002, Academic radiology.

Fluorescence Reflectance Imaging of Macrophage-Rich Atherosclerotic Plaques Using an αvβ3 Integrin–Targeted Fluorochrome

W. Heindel, C. Bremer, M. Schäfers, 2008, Journal of Nuclear Medicine.

Determination of extent and activity with radionuclide imaging in Erdheim-Chester disease.

O. Schober, C. Franzius, C. Bremer, 1999, Clinical nuclear medicine.

Alarmin S 100 A 8 / S 100 A 9 as a biomarker for molecular imaging of local inflammatory activity

C. Bremer, M. Schäfers, T. Vogl, 2017 .

Acute myeloid leukemia presenting with a uterus tumor

J. Tchinda, C. Bremer, R. Parwaresch, 2005, Annals of Hematology.

MR‐monitored LITT as a palliative concept in patients with high grade gliomas: Preliminary clinical experience

G. Schuierer, C. Bremer, T. Allkemper, 1998, Journal of magnetic resonance imaging : JMRI.

Fluorescent non-peptidic RGD mimetics with high selectivity for αVβ3 vs αIIbβ3 integrin receptor: novel probes for in vivo optical imaging.

C. Bremer, M. Schäfers, M. Eisenblätter, 2014, Journal of medicinal chemistry.

Molecular imaging of MMP expression and therapeutic MMP inhibition.

R. Weissleder, C. Tung, C. Bremer, 2002, Academic radiology.