K. Tichauer

发表

Quantitative in vivo cell-surface receptor imaging in oncology: kinetic modeling and paired-agent principles from nuclear medicine and optical imaging

Jonathan T. C. Liu, B. Pogue, K. Tichauer, 2015, Physics in medicine and biology.

Measurement of Cerebral Oxidative Metabolism with Near-Infrared Spectroscopy: A Validation Study

Ting-Yim Lee, K. Tichauer, J. Hadway, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cerebral metabolic rate of oxygen and amplitude-integrated electroencephalography during early reperfusion after hypoxia-ischemia in piglets.

Ting-Yim Lee, K. Tichauer, K. St. Lawrence, 2009, Journal of applied physiology.

Continuous monitoring of absolute cerebral blood flow by near-infrared spectroscopy during global and focal temporary vessel occlusion.

Ting-Yim Lee, K. Tichauer, M. Diop, 2011, Journal of applied physiology.

Near-infrared spectroscopy measurements of cerebral blood flow and oxygen consumption following hypoxia-ischemia in newborn piglets

Ting-Yim Lee, K. Tichauer, J. Hadway, 2005, Journal of applied physiology.

Comparison of time-resolved and continuous-wave near-infrared techniques for measuring cerebral blood flow in piglets.

Ting-Yim Lee, K. Tichauer, M. Diop, 2010, Journal of biomedical optics.

Quantitative measurement of cerebral blood flow in a juvenile porcine model by depth-resolved near-infrared spectroscopy.

Ting-Yim Lee, K. Tichauer, M. Diop, 2010, Journal of biomedical optics.

Time-resolved near-infrared technique for bedside monitoring of absolute cerebral blood flow

Kenneth M. Tichauer, Keith St. Lawrence, Ting-Yim Lee, 2010, BiOS.

Near-infrared spectroscopy measurements of cerebral blood flow and oxygen consumption following hypoxia-ischemia in newborn piglets

Ting-Yim Lee, K. Tichauer, J. Hadway, 2006 .

A broadband continuous-wave multichannel near-infrared system for measuring regional cerebral blood flow and oxygen consumption in newborn piglets.

Ting-Yim Lee, K. Tichauer, M. Diop, 2009, The Review of scientific instruments.

Dynamic dual-tracer MRI-guided fluorescence tomography to quantify receptor density in vivo

Sophie J Deharvengt, Kristian J. Sexton, B. Pogue, 2013, Proceedings of the National Academy of Sciences.

In Vivo Quantification of Tumor Receptor Binding Potential with Dual-Reporter Molecular Imaging

Jason R. Gunn, Brian W. Pogue, Tayyaba Hasan, 2012, Molecular Imaging and Biology.

Microscopic lymph node tumor burden quantified by macroscopic dual-tracer molecular imaging

Tayyaba Hasan, Brian W Pogue, P Jack Hoopes, 2014, Nature Medicine.

Noninvasive detection of cancer spread to lymph nodes: A review of molecular imaging principles and protocols

K. Tichauer, Chengyue Li, V. Torres, 2018, Journal of surgical oncology.

Nodal lymph flow quantified with afferent vessel input function allows differentiation between normal and cancer-bearing nodes.

Brian W Pogue, Alisha V DSouza, Richard J Barth, 2015, Biomedical optics express.

Quantitative Fluorescence Molecular Imaging through Kinetic Modeling and Paired Agent Methods

Kenneth M. Tichauer, Xiaochun Xu, Negar Sadeghipour, 2019, Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP).

Depth resolution and multiexponential lifetime analyses of reflectance-based time-domain fluorescence data.

Ting-Yim Lee, K. Tichauer, M. Diop, 2011, Applied optics.

Pixel-based absorption correction for dual-tracer fluorescence imaging of receptor binding potential.

B. Pogue, K. Tichauer, J. Gunn, 2014, Biomedical optics express.

Advantages of a dual-tracer model over reference tissue models for binding potential measurement in tumors

T. Hasan, K. Tichauer, K. Samkoe, 2012, Physics in medicine and biology.

Quantification of the binding potential of cell-surface receptors in fresh excised specimens via dual-probe modeling of SERS nanoparticles

Jovan G. Brankov, Kenneth M. Tichauer, Cynthia Yang, 2015, Scientific Reports.

Rinsing paired-agent model (RPAM) to quantify cell-surface receptor concentrations in topical staining applications of thick tissues

Xiaochun Xu, Jialing Xiang, Yu Wang, 2017, Physics in medicine and biology.

Microscopic investigation of" topically applied nanoparticles for molecular imaging of fresh tissue surfaces

Xiaochun Xu, Kenneth M Tichauer, Yu Winston Wang, 2018, Journal of biophotonics.

Improved tumor contrast achieved by single time point dual-reporter fluorescence imaging.

Tayyaba Hasan, Brian W Pogue, Kenneth M Tichauer, 2012, Journal of biomedical optics.

Biomaterials with persistent growth factor gradients in vivo accelerate vascularized tissue formation.

Kenneth M. Tichauer, Eric M. Brey, Banu Akar, 2015, Biomaterials.

Comparison of Monte Carlo and Diffusion Approximation Light Modeling in Small Animal Fluorescence Tomography

B. Pogue, K. Tichauer, K. S. Lawrence, 2012 .

Modeling the binding and diffusion of receptor-targeted nanoparticles topically applied on fresh tissue specimens

Jonathan T. C. Liu, K. Tichauer, Y. Wang, 2019, Physics in medicine and biology.

Perfusion CT estimates photosensitizer uptake and biodistribution in a rabbit orthotopic pancreatic cancer model: a pilot study.

B. Pogue, T. Hasan, Ting-Yim Lee, 2015, Academic radiology.

Design and characterization of a dead-time regime enhanced early photon projection imaging system.

K. Tichauer, J. Brankov, A. Giudice, 2018, The Review of scientific instruments.

Enhanced detection of early photons in time-domain optical tomography using dead-time characteristics of SPADs

Wei Zhou, Jovan G. Brankov, Kenneth M. Tichauer, 2016 .

Time Domain Diffuse Fluorescence Tomography Can Increase Small-Animal Imaging Throughput

B. Pogue, H. Dehghani, K. Tichauer, 2012 .

Time-bin Optimization in Time-resolved Near Infrared Fluorescence Tomography

B. Pogue, H. Dehghani, K. Tichauer, 2012 .

Noninvasive quantification of target availability during therapy using paired-agent fluorescence tomography

K. Tichauer, S. Davis, K. Samkoe, 2020, Theranostics.

Kinetic model optimization for characterizing tumour physiology by dynamic contrast-enhanced near-infrared spectroscopy

K. Tichauer, M. Diop, K. Verdecchia, 2013, Physics in medicine and biology.

Angular domain fluorescence lifetime imaging: a tissue-like phantom study.

Ting-Yim Lee, K. Tichauer, J. Carson, 2010, Optics express.

Direct Characterization of Arterial Input Functions by Fluorescence Imaging of Exposed Carotid Artery to Facilitate Kinetic Analysis

Kristian J. Sexton, B. Pogue, K. Tichauer, 2014, Molecular Imaging and Biology.

Design, Synthesis, and Biological Evaluation of Polyaminocarboxylate Ligand‐Based Theranostic Conjugates for Antibody‐Targeted Cancer Therapy and Near‐Infrared Optical Imaging

David D. L. Minh, K. Tichauer, T. Nguyen, 2018, ChemMedChem.

Targeted tracer kinetic modeling improves the accuracy of fluorescence-guided surgery in a rat glioblastoma multiforme model

Kristian J. Sexton, B. Pogue, K. Tichauer, 2014 .

Optimizing the protocol for retinal vascular permeability mapping from fluorescein video angiography data

Jennifer J. Kang-Mieler, C. Cheung, K. Tichauer, 2022, BiOS.

Measurement of Cerebral Oxidative Metabolism with Near-Infrared Spectroscopy: A Validation Study

Ting-Yim Lee, K. Tichauer, J. Hadway, 2007 .

In Situ Therapeutic Response Imaging through Quantification of Drug Distribution and Proteomic Response

Antonio R. Montaño, Summer L. Gibbs, Nathan P. McMahon, 2021, Biophotonics Congress 2021.

First experience imaging short-wave infrared fluorescence in a large animal: indocyanine green angiography of a pig brain

K. Paulsen, K. Tichauer, S. Davis, 2019, Journal of biomedical optics.

In-network fractional calculations using P4 for scientific computing workloads

K. Tichauer, J. Kowalkowski, M. Wang, 2022, EuroP4@CoNEXT.

Mean transit time as an index of cerebral perfusion pressure in experimental systemic hypotension

Ting-Yim Lee, K. Tichauer, Xiaogang Chen, 2011, Physiological measurement.

Dipyridamole Treatment Prior to Stroke Onset: Examining Post-stroke Cerebral Circulation and Outcome in Rabbits

Ting-Yim Lee, K. Tichauer, R. Aviv, 2011, Translational Stroke Research.

Simultaneous extracellular and intracellular quantification of EGFR using paired-agent imaging in an in ovo tumor model

Kenneth M. Tichauer, Kimberley S. Samkoe, Allison Solanki, 2019, BiOS.

Comparison of time- and angular-domain scatter rejection in mesoscopic optical projection tomography: a simulation study.

K. Tichauer, J. Brankov, C. Li, 2019, Biomedical optics express.

Noninvasive in vivo mapping of intracellular signaling proteins using a pairing of targeted and untargeted fluorescently labeled small molecule kinase inhibitors

Lei Wang, Kenneth M. Tichauer, Summer L. Gibbs, 2020, BiOS.

TRIPODD: a Novel Fluorescence Imaging Platform for In Situ Quantification of Drug Distribution and Therapeutic Response

Antonio R. Montaño, Summer L. Gibbs, Nathan P. McMahon, 2021, Molecular Imaging and Biology.

Cranial nerve contrast using nerve-specific fluorophores improved by paired-agent imaging with indocyanine green as a control agent

Kenneth M. Tichauer, Richard W. Byrne, Todd Wilson, 2017 .

Comparison of Kinetic Models for Dual-Tracer Receptor Concentration Imaging in Tumors.

Tayyaba Hasan, Brian W Pogue, Nazanin Hamzei, 2014, Austin journal of biomedical engineering.

High Vascular Delivery of EGF, but Low Receptor Binding Rate Is Observed in AsPC-1 Tumors as Compared to Normal Pancreas

Brian W. Pogue, Tayyaba Hasan, Kenneth M. Tichauer, 2011, Molecular Imaging and Biology.

Is tumor cell specificity distinct from tumor selectivity in vivo? A quantitative NIR molecular imaging analysis of nanoliposome targeting

B. Pogue, T. Hasan, K. Tichauer, 2020, Nano Research.

Characterization of an angular domain fluorescence optical projection tomography system for mesoscopic lymph node imaging.

W. Zhou, K. Tichauer, J. Brankov, 2020, Applied optics.

Methods for effective fluorophore injection and imaging of lymphatics in small animals

Jason R. Gunn, Kenneth M. Tichauer, Brian W. Pogue, 2016, SPIE BiOS.

Protease-Sensitive Hydrogel Biomaterials with Tunable Modulus and Adhesion Ligand Gradients for 3D Vascular Sprouting.

D. Venerus, K. Tichauer, Chengyue Li, 2018, Biomacromolecules.

Quantitative in vivo immunohistochemistry of epidermal growth factor receptor using a receptor concentration imaging approach.

Tayyaba Hasan, Brian W Pogue, Wendy A Wells, 2014, Cancer research.

Generalized paired-agent kinetic model for in vivo quantification of cancer cell-surface receptors under receptor saturation conditions

K. Tichauer, S. Davis, N. Sadeghipour, 2017, Physics in medicine and biology.

Accounting for pharmacokinetic differences in dual-tracer receptor density imaging

T. Hasan, K. Tichauer, M. Diop, 2014, Physics in medicine and biology.

Dual-tracer receptor concentration imaging using tracers with different tissue delivery kinetics

Brian W. Pogue, Tayyaba Hasan, Kenneth M. Tichauer, 2014, Photonics West - Biomedical Optics.

Examining the Feasibility of Quantifying Receptor Availability Using Cross-Modality Paired-Agent Imaging

K. Tichauer, S. Davis, K. Samkoe, 2021, Molecular Imaging and Biology.

Intraoperative Detection of Micrometastases in Whole Excised Lymph Nodes Using Fluorescent Paired-Agent Imaging Principles: Identification of a Suitable Staining and Rinsing Protocol

K. Tichauer, J. Brankov, K. Samkoe, 2021, Molecular Imaging and Biology.

Thick tissue diffusion model with binding to optimize topical staining in fluorescence breast cancer margin imaging

Yu Wang, Kenneth M. Tichauer, Xiaochun Xu, 2018, BiOS.

Ex-vivo tissue classification of cell surface receptor concentrations using kinetic modeling

Kenneth M. Tichauer, Lagnojita Sinha, Yu Wang, 2015, Photonics West - Biomedical Optics.

Angular restriction fluorescence optical projection tomography to localize micrometastases in lymph nodes

K. Tichauer, J. Brankov, Chengyue Li, 2019, Journal of biomedical optics.

Fluorescent Affibody Peptide Penetration in Glioma Margin Is Superior to Full Antibody

Brian W. Pogue, Kimberley S. Samkoe, Jason Gunn, 2013, PloS one.

OregonFluor enables quantitative intracellular paired agent imaging to assess drug target availability in live cells and tissues

Antonio R. Montaño, William H. Bisson, Summer L. Gibbs, 2023, Nature Chemistry.

A dual-reporter fluorescent imaging approach can be used to estimate sentinel lymph node tumor burden

Ramesh Govindan, Jason R. Gunn, Brian W. Pogue, 2013, Photonics West - Biomedical Optics.

Intracellular paired agent imaging enables improved evaluation of tyrosine kinase inhibitor target engagement

Lei Wang, Summer L. Gibbs, Kimberley S. Samkoe, 2020, BiOS.

Enhanced detection of early photons in time-domain optical imaging by running in the "dead-time" regime.

K. Tichauer, J. Brankov, L. Sinha, 2016, Optics letters.

Fluorescence mesoscopic imaging of whole lymph nodes for intraoperative sentinel lymph node biopsy procedures

M. Witjes, K. Tichauer, J. Brankov, 2023, BiOS.

Improved Discrimination of Tumors with Low and Heterogeneous EGFR Expression in Fluorescence-Guided Surgery Through Paired-Agent Protocols

K. Tichauer, J. Gunn, E. Chen, 2021, Molecular Imaging and Biology.

Quantitative Drug Target Imaging Using Paired-Agent Principles

Summer L. Gibbs, Jonathan T. C. Liu, K. Tichauer, 2021 .

Model-based system matrix for iterative reconstruction in sub-diffuse angular-domain fluorescence optical projection tomography.

K. Tichauer, J. Brankov, Chengyue Li, 2021, Biomedical optics express.

Paired-Agent Fluorescence Molecular Imaging of Sentinel Lymph Nodes Using Indocyanine Green as a Control Agent for Antibody-Based Targeted Agents

Nathan P. McMahon, K. Tichauer, Chengyue Li, 2019, Contrast media & molecular imaging.

Deriving clinical parameters for paired agent imaging in head and neck squamous cell carcinomas: efficient methodology for the measurement of plasma fluorescence

K. Paulsen, K. Tichauer, J. Elliott, 2023, BiOS.

Rapid and Quantitative Intraoperative Pathology-Assisted Surgery by Paired-Agent Imaging-Derived Confidence Map

K. Tichauer, E. Chen, P. Hoopes, 2022, Molecular Imaging and Biology.

Nonlinear unmixing to account for blood absorption in multispectral imaging for improved quantification of intracellular and extracellular EGFR

Summer L. Gibbs, Nathan P. McMahon, K. Tichauer, 2022, BiOS.

Intraoperative micrometastases detection using paired-agent fluorescent imaging: trial-and-error protocol development

Jovan G. Brankov, Kenneth M. Tichauer, Xiaochun Xu, 2021, BiOS.

Lymph node micrometastases detection using paired-agent imaging protocol with biological tissue model

Jovan G. Brankov, Kenneth M. Tichauer, Xiaochun Xu, 2020, BiOS.

Protocol development of paired-agent fluorescent imaging to detect micrometastases in resected breast lymph nodes

Xiaochun Xu, Chengyue Li, Veronica C. Torres, 2019, BiOS.

Paired-agent fluorescent imaging to detect micrometastases in breast sentinel lymph node biopsy: experiment design and protocol development

Jovan G. Brankov, Kenneth M. Tichauer, Xiaochun Xu, 2018, BiOS.

Monitoring cancer cell surface receptor expression during anti-angiogenesis therapy in vivo

Scott C. Davis, Kimberley S. Samkoe, Kenneth Tichauer, 2021, BiOS.

Paired-agent imaging for detection of head and neck cancers

Kenneth M. Tichauer, Kimberley S. Samkoe, Kayla Marra, 2019, BiOS.

Using near-infrared spectroscopy to measure cerebral metabolic rate of oxygen under multiple levels of arterial oxygenation in piglets.

David S. C. Lee, Ting-Yim Lee, K. Tichauer, 2010, Journal of applied physiology.

Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers

Jason R. Gunn, Brian W. Pogue, Kenneth M. Tichauer, 2012, Journal of visualized experiments : JoVE.

Toward whole-body optical imaging of rats using single-photon counting fluorescence tomography.

Brian W Pogue, Frederic Leblond, Fadi El-Ghussein, 2011, Optics letters.

Changes in Cerebral Oxygen Consumption and High-Energy Phosphates During Early Recovery in Hypoxic-Ischemic Piglets: A Combined Near-Infrared and Magnetic Resonance Spectroscopy Study

Ting-Yim Lee, Kenneth M Tichauer, Jeff D Winter, 2009, Pediatric Research.

Quantifying cancer cell receptors with paired-agent fluorescent imaging: a novel method to account for tissue optical property effects

Scott C Davis, Negar Sadeghipour, Kenneth M Tichauer, 2018, BiOS.

Singular value decomposition metrics show limitations of detector design in diffuse fluorescence tomography

Brian W. Pogue, Kenneth M. Tichauer, Frederic Leblond, 2010, Biomedical optics express.

Dual-tracer background subtraction approach for fluorescent molecular tomography

Scott C Davis, Brian W Pogue, Frederic Leblond, 2013, Journal of biomedical optics.

Assessing the Severity of Perinatal Hypoxia-Ischemia in Piglets Using Near-Infrared Spectroscopy to Measure the Cerebral Metabolic Rate of Oxygen

Ting-Yim Lee, K. Tichauer, J. Hadway, 2009, Pediatric Research.

Iterative reconstruction using Monte Carlo generated system matrix for angle-restricted optical tomography

Jovan G. Brankov, Kenneth M. Tichauer, Veronica C. Torres, 2021, BiOS.

Excised Whole Lymph Node Imaging for Cancer Staging with Angular Restriction Dual Fluorescent Optical Projection Tomography

Jovan G. Brankov, Kenneth M. Tichauer, Lagnojita Sinha, 2019, 2019 IEEE 16th International Symposium on Biomedical Imaging (ISBI 2019).

Staining and rinsing protocol in excised lymph node using paired-agent fluorescence imaging to detect micrometastases

K. Tichauer, J. Brankov, Chengyue Li, 2019, Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP).

Information loss and reconstruction in diffuse fluorescence tomography.

Brian W. Pogue, Kenneth M. Tichauer, Frederic Leblond, 2012, Journal of the Optical Society of America. A, Optics, image science, and vision.

Design of optical molecular imaging protocols through predictive task-based evaluations

K. Tichauer, S. Davis, K. Samkoe, 2021, Biophotonics Congress 2021.

An overview of time-domain diffuse fluorescence imaging: instrumentation and applications

Brian W. Pogue, Kenneth M. Tichauer, Frederic Leblond, 2013, Photonics West - Biomedical Optics.

Imaging workflow and calibration for CT-guided time-domain fluorescence tomography

Brian W. Pogue, Kenneth M. Tichauer, Hamid Dehghani, 2011, Biomedical optics express.

A three-dimensional finite element model and image reconstruction algorithm for time-domain fluorescence imaging in highly scattering media

H Dehghani, K. Vishwanath, H. Dehghani, 2011, Physics in medicine and biology.

Tumor Endothelial Marker Imaging in Melanomas Using Dual-Tracer Fluorescence Molecular Imaging

Jason R. Gunn, Brian W. Pogue, Tayyaba Hasan, 2014, Molecular Imaging and Biology.

Quantitative fluorescence molecular imaging in highly light-absorbing melanomas using a dual-tracer kinetic modeling normalization method

Tayyaba Hasan, Kenneth M. Tichauer, Stephen C. Kanick, 2014, Photonics West - Biomedical Optics.

Using near-infrared spectroscopy to measure the changes in cerebral blood flow and oxygen metabolism following hypoxia ischemia in newborn piglets

Ting-Yim Lee, K. Tichauer, J. Hadway, 2004 .

arterial oxygenation in piglets metabolic rate of oxygen under multiple levels of Using near-infrared spectroscopy to measure cerebral

David S. C. Lee, Ting-Yim Lee, C. Cooper, 2015 .

Quantitative Cerebral Metabolism Measurements with NIRS: Application to Neonatal Brain Injury

Ting-Yim Lee, K. Tichauer, J. Hadway, 2008 .

Novel Near-Infrared Fluorescent Agent for Imaging Human Prostate Carcinoma in an Athymic Mouse Model

Ting-Yim Lee, K. Tichauer, K. S. Lawrence, 2010 .

Fast Monte Carlo fitting of two-layered tissue structures for short source-detector distances

Kenneth M. Tichauer, Keith St. Lawrence, Mamadou Diop, 2011, BiOS.

@Western Scholarship@Western

K. Tichauer, Keith St, Mark Migueis, 2022 .

Lymph node microscopic tumor burden quantified in vivo with dual tracer receptor-targeted imaging

B. Pogue, T. Hasan, K. Tichauer, 2014 .

Identification of a Suitable Untargeted Agent for the Clinical Translation of ABY-029 Paired-Agent Imaging in Fluorescence-Guided Surgery

K. Tichauer, E. Chen, P. Hoopes, 2021, Molecular Imaging and Biology.

Improved Tumor Discrimination and Shortened Administration-to-Imaging Times in Fluorescence Guided Surgery Through Paired-Agent Protocols

K. Tichauer, J. Gunn, K. Samkoe, 2020 .

Improved identification of cranial nerves using paired-agent imaging: topical staining protocol optimization through experimentation and simulation

Kenneth M. Tichauer, Richard W. Byrne, Veronica C. Torres, 2018, BiOS.

Compressive sensing based reconstruction in bioluminescence tomography improves image resolution and robustness to noise

Kenneth M. Tichauer, Hamid Dehghani, Frederic Leblond, 2012, Biomedical optics express.

In situ single-cell therapeutic response imaging facilitated by the TRIPODD fluorescence imaging platform

Antonio R. Montaño, Summer L. Gibbs, Nathan P. McMahon, 2024, Theranostics.