C. Garlanda

N. Rothwell, C. Garlanda, S. Allan, 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

PTX3 expression in the heart tissues of patients with myocardial infarction and infectious myocarditis.

C. Garlanda, A. Mantovani, F. Pasqualini, 2011, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.

The long pentraxin PTX3: a modulator of the immunoinflammatory response in atherosclerosis and cardiovascular diseases.

C. Garlanda, G. Norata, A. Catapano, 2010, Trends in cardiovascular medicine.

The soluble pattern recognition receptor pentraxin-3 in innate immunity, inflammation and fertility.

C. Garlanda, Virginia Maina, A. Cotena, 2009, Journal of reproductive immunology.

Complement Dependent Amplification of the Innate Response to a Cognate Microbial Ligand by the Long Pentraxin PTX31

C. Garlanda, A. Mantovani, M. Daha, 2007, The Journal of Immunology.

The long pentraxin PTX3 in vascular pathology.

C. Garlanda, A. Mantovani, R. Latini, 2006, Vascular pharmacology.

IL-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex IL-1R5/IL-1R8

E. Eisenmesser, C. Garlanda, C. Dinarello, 2021, Theranostics.

IL-37 exerts therapeutic effects in experimental autoimmune 1 encephalomyelitis through the receptor complex IL-1 R 5 / IL-1 R 8 2

E. Eisenmesser, C. Garlanda, C. Dinarello, 2020 .

The long pentraxin PTX3: from innate immunity to ischemic heart disorders

C. Garlanda, A. Mantovani, A. Maggioni, 2004 .

Membrane and soluble pattern recognition receptors: the unique functions of the long pentraxin PTX3

C. Garlanda, A. Mantovani, G. Peri, 2004 .

Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response

C. Garlanda, A. Mantovani, E. Hirsch, 2002, Nature.

Occurrence and significance of tumor‐associated neutrophils in patients with colorectal cancer

C. Garlanda, A. Mantovani, M. Roncalli, 2016, International journal of cancer.

Influence of Pentraxin 3 (PTX3) Genetic Variants on Myocardial Infarction Risk and PTX3 Plasma Levels

C. Specchia, C. Garlanda, A. Mantovani, 2012, PloS one.

PTX3, a Humoral Pattern Recognition Molecule, in Innate Immunity, Tissue Repair, and Cancer.

C. Garlanda, A. Mantovani, B. Bottazzi, 2018, Physiological reviews.

Recognition of Neisseria meningitidis by the Long Pentraxin PTX3 and Its Role as an Endogenous Adjuvant

R. Rappuoli, C. Garlanda, A. Mantovani, 2015, PloS one.

The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.

C. Garlanda, A. Mantovani, A. Markotić, 2014, Immunity.

Early and Transient Release of Leukocyte Pentraxin 3 during Acute Myocardial Infarction

C. Garlanda, A. Mantovani, A. Maseri, 2011, The Journal of Immunology.

Optical in vivo imaging detection of preclinical models of gut tumors through the expression of integrin αVβ3

P. Allavena, C. Garlanda, A. Mantovani, 2018, Oncotarget.

Long Pentraxin 3/Tumor Necrosis Factor-Stimulated Gene-6 Interaction: A Biological Rheostat for Fibroblast Growth Factor 2–Mediated Angiogenesis

C. Garlanda, R. Bianchi, M. Sironi, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Interleukin-1 in tumor progression, therapy, and prevention.

C. Garlanda, A. Mantovani, A. Mantovani, 2021, Cancer cell.

The Interleukin-1 Family

C. Garlanda, S. Jaillon, 2016 .

C. Garlanda, A. Mantovani, C. Dinarello, 2020 .

High IL-1R8 expression in breast tumors promotes tumor growth and contributes to impaired antitumor immunity

A. Camargo, Fábio C. P. Navarro, C. Garlanda, 2017, Oncotarget.

Pseudomonas Protects Neonate Mice from in Breast Milk, Spreads in Tissues, and Prototypic Long Pentraxin PTX3 Is Present

C. Garlanda, A. Mantovani, G. Mancuso, 2013 .

Expression by through Direct Inhibition of Innate IL-17 A Regulates Psoriasiform Inflammation Related Receptor − Toll IL-1 R 8 / Single Ig IL-1

C. Garlanda, A. Mantovani, P. Fallon, 2013 .

Toll IL-1R8/Single Ig IL-1–Related Receptor Regulates Psoriasiform Inflammation through Direct Inhibition of Innate IL-17A Expression by γδ T Cells

C. Garlanda, A. Mantovani, P. Fallon, 2013, The Journal of Immunology.

Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure

C. Garlanda, A. Buffo, A. Uccelli, 2019, Acta Neuropathologica.

Immunohistochemical localization of the murine transferrin receptor (TfR) on blood–tissue barriers using a novel anti-TfR monoclonal antibody

B. Engelhardt, C. Garlanda, A. Vecchi, 1998, Histochemistry and Cell Biology.

Pseudomonas aeruginosa Chronic Lung Infection Caused by Pattern Recognition Molecule PTX3 in The Therapeutic Potential of the Humoral

C. Garlanda, S. Mantero, A. Bragonzi, 2011 .

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling.

C. Garlanda, A. Mantovani, F. Pasqualini, 2015, The Journal of investigative dermatology.

Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra.

M. Jaeger, M. Netea, C. Garlanda, 2015, Cell host & microbe.

Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection

G. Rossi, C. Garlanda, M. Bernardini, 2018, PLoS pathogens.

Response of CFTR-deficient mice to long-term chronic Pseudomonas aeruginosa infection and PTX3 therapy.

C. Garlanda, A. Mantovani, A. Bragonzi, 2013, The Journal of infectious diseases.

Nonredundant role of CCRL2 in lung dendritic cell trafficking.

C. Garlanda, A. Mantovani, E. Hirsch, 2010, Blood.

Ligands and Receptors of the Interleukin-1 Family in Immunity and Disease

C. Garlanda, A. Mantovani, 2013, Front. Immunol..

Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19.

R. Rappuoli, C. Garlanda, L. Varani, 2022, Nature immunology.

PTX3 as a potential endothelial dysfunction biomarker for severity of preeclampsia and IUGR.

C. Garlanda, S. Calabrese, I. Cetin, 2012, Placenta.

Pentraxins and atherosclerosis: the role of PTX3.

C. Garlanda, A. Mantovani, R. Latini, 2011, Current pharmaceutical design.

Macrophages as tools and targets in cancer therapy

P. Allavena, C. Garlanda, A. Mantovani, 2022, Nature Reviews Drug Discovery.

Resident Dendritic Cells Prevent Postischemic Acute Renal Failure by Help of Single Ig IL-1 Receptor-Related Protein1

C. Garlanda, A. Mantovani, H. Anders, 2009, The Journal of Immunology.

Single Ig IL-1 Receptor-Related Protein Postischemic Acute Renal Failure by Help of Resident Dendritic Cells Prevent

C. Garlanda, H. Anders, S. Segerer, 2009 .

AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

C. Garlanda, A. Mantovani, M. Colonna, 2011, Nature Immunology.

Evolution of the Pentraxin Family: The New

C. Garlanda, M. Fabbri, M. Nebuloni, 2010 .

Inflammatory reaction and implantation: the new entries PTX3 and D6.

C. Garlanda, M. Locati, M. Nebuloni, 2008, Placenta.

Inflammatory reaction and implantation: the new entries PTX3 and D6

C. Garlanda, M. Locati, M. Nebuloni, 2009 .

First trimester PTX 3 levels in women who subsequently develop preeclampsia and fetal growth restriction

A. Papageorghiou, C. Garlanda, I. Cetin, 2009 .

Complement activation in cancer: Effects on tumor-associated myeloid cells and immunosuppression.

C. Garlanda, Luna Minute, Elena Magrini, 2022, Seminars in immunology.

Tir8/Sigirr prevents murine lupus by suppressing the immunostimulatory effects of lupus autoantigens

C. Garlanda, A. Mantovani, H. Anders, 2008, The Journal of experimental medicine.

Tir 8 / Sigirr prevents murine lupus by suppressing the immunostimulatory eff ects of lupus autoantigens

C. Garlanda, H. Anders, M. Lech, 2008 .

Complement as a target in COVID-19?

C. Garlanda, J. Lambris, M. Huber-Lang, 2020, Nature Reviews Immunology.

Circulating pentraxin 3 in severe COVID‐19 or other pulmonary sepsis

C. Garlanda, A. Mantovani, M. Cecconi, 2021, European journal of clinical investigation.

IL1R8 DEFICIENCY DRIVES AUTOIMMUNITY-ASSOCIATED

Hans-Joachim, Simonetti, C. Garlanda, 2019 .

Repeated 5-day cycles of low dose aldesleukin in amyotrophic lateral sclerosis (IMODALS): A phase 2a randomised, double-blind, placebo-controlled trial

A. Al-Chalabi, C. Garlanda, P. Leigh, 2020, EBioMedicine.

Lack of SIGIRR/TIR8 aggravates hydrocarbon oil‐induced lupus nephritis

C. Garlanda, A. Mantovani, H. Anders, 2010, The Journal of pathology.

IL‐1F5 mediates anti‐inflammatory activity in the brain through induction of IL‐4 following interaction with SIGIRR/TIR8

M. Lynch, C. Garlanda, A. Mantovani, 2008, Journal of neurochemistry.

The Long Pentraxin 3 Contributes to Joint Inflammation in Gout by Facilitating the Phagocytosis of Monosodium Urate Crystals

C. Garlanda, A. Mantovani, M. Teixeira, 2019, The Journal of Immunology.

Antibody against murine PECAM-1 inhibits tumor angiogenesis in mice

C. Garlanda, H. DeLisser, Zhao Zhou, 2004, Angiogenesis.

IL-1 family nomenclature

L. Joosten, M. Netea, Dirk E. Smith, 2010, Nature Immunology.

The Long Pentraxin PTX3 Is an Endogenous Inhibitor of Hyperoxaluria-Related Nephrocalcinosis and Chronic Kidney Disease

P. Boor, C. Garlanda, A. Mantovani, 2018, Front. Immunol..

Tuning of inflammatory cytokines and toll-like receptors by TIR8/SIGIRR, a member of the IL-1 receptor family with unique structure and regulation

C. Garlanda, A. Mantovani, M. Mosca, 2006 .

An Alternative Role of C1q in Cell Migration and Tissue Remodeling: Contribution to Trophoblast Invasion and Placental Development

C. Garlanda, C. Tripodo, A. Santoni, 2010, The Journal of Immunology.

DevelopmentTrophoblast Invasion and Placental and Tissue Remodeling: Contribution to An Alternative Role of C1q in Cell Migration

C. Garlanda, C. Tripodo, A. Santoni, 2010 .

Absence of Toll-IL-1 receptor 8/single immunoglobulin IL-1 receptor-related molecule reduces house dust mite-induced allergic airway inflammation in mice.

C. Garlanda, A. Mantovani, S. Phipps, 2013, American journal of respiratory cell and molecular biology.

Pentraxin‐3 is upregulated in the central nervous system during MS and EAE, but does not modulate experimental neurological disease

C. Garlanda, A. Mantovani, R. Furlan, 2016, European journal of immunology.

Chemokines and Chemokine Receptors

P. Allavena, C. Garlanda, A. Mantovani, 1999 .

Evidence for a DC‐Specific Inhibitory Mechanism that Depends on MyD88 and SIGIRR

C. Garlanda, A. Mantovani, M. Feldmann, 2010, Scandinavian journal of immunology.

C. Garlanda, F. Dieli, A. Salerno, 2013 .

Damping Excessive Inflammation and Tissue Damage in Mycobacterium tuberculosis Infection by Toll IL-1 Receptor 8/Single Ig IL-1-Related Receptor, a Negative Regulator of IL-1/TLR Signaling1

C. Garlanda, A. Mantovani, M. L. La Manna, 2007, The Journal of Immunology.

IL-1 / TLR Signaling IL-1-Related Receptor , a Negative Regulator Infection by Toll IL-1 Receptor 8 / Single Ig Mycobacterium tuberculosis Damage in Damping Excessive Inflammation and Tissue

C. Garlanda, F. Dieli, A. Salerno, 2007 .

Pentraxin 3 plasma levels at graft-versus-host disease onset predict disease severity and response to therapy in children given haematopoietic stem cell transplantation

C. Garlanda, A. Mantovani, M. Valsecchi, 2016, Oncotarget.

Intrahepatic CD69+Vδ1 T cells re-circulate in the blood of patients with metastatic colorectal cancer and limit tumor progression

C. Peano, C. Garlanda, A. Mantovani, 2022, Journal for ImmunoTherapy of Cancer.

The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps

C. Garlanda, A. Mantovani, H. Gascan, 2007, The Journal of experimental medicine.

The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3

C. Garlanda, K. Klingel, M. Sauter, 2016, European journal of immunology.

The “sweet” side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

C. Garlanda, A. Mantovani, P. Reading, 2013, Front. Immun..

Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models.

C. Garlanda, A. Mantovani, G. Simonetti, 2011, Blood.

Toll-Like Receptor Signaling and SIGIRR in Renal Fibrosis upon Unilateral Ureteral Obstruction

C. Garlanda, A. Mantovani, H. Anders, 2011, PloS one.

Pro-inflammatory M1/Th1 type immune network and increased expression of TSG-6 in the eutopic endometrium from women with endometriosis.

M. Neri, C. Garlanda, E. Cicinelli, 2017, European journal of obstetrics, gynecology, and reproductive biology.

Intraperitoneal adoptive transfer of mesenchymal stem cells enhances recovery from acid aspiration acute lung injury in mice

C. Garlanda, A. Mantovani, A. Pesenti, 2017, Intensive Care Medicine Experimental.

Extracellular and nuclear roles of IL-37 after spinal cord injury

E. Eisenmesser, C. Garlanda, C. Dinarello, 2020, Brain, Behavior, and Immunity.

Extracellular forms of IL-37 inhibit innate inflammation in vitro and in vivo but require the IL-1 family decoy receptor IL-1R8

B. Palmer, C. Garlanda, A. Mantovani, 2015, Proceedings of the National Academy of Sciences.

Platelet-macrophage partnership in innate immunity and inflammation

C. Garlanda, A. Mantovani, 2013, Nature Immunology.

Long pentraxin 3 (PTX3) levels predict death, intubation and thrombotic events among hospitalized patients with COVID-19

C. Garlanda, M. Valsecchi, A. Biondi, 2022, Frontiers in Immunology.

Clearance of Cell Remnants and Regeneration of Injured Muscle Depend on Soluble Pattern Recognition Receptor PTX3

C. Garlanda, A. Mantovani, A. Castiglioni, 2016, Molecular medicine.

Interleukin-1α and HMGB1 Mediate Hippocampal Dysfunction in SIGIRR-Deficient Mice

M. Lynch, C. Garlanda, M. Watson, 2011, The Journal of Neuroscience.

IL-1 α and HMGB 1 mediate hippocampal dysfunction in SIGIRR-deficient mice Abbreviated title : SIGIRR deficiency leads to hippocampal dysfunction

M. Lynch, C. Garlanda, M. Watson, 2011 .

The interleukin-1 family: back to the future.

C. Garlanda, A. Mantovani, C. Dinarello, 2013, Immunity.

187: Interleukin 37 employs the IL-1 family inhibitory receptor SIGIRR and the alpha chain of the IL-18 receptor to suppress innate immunity

C. Garlanda, A. Mantovani, C. Dinarello, 2013 .

TLR3 preconditioning induces anti-inflammatory and anti-ictogenic effects in mice mediated by the IRF3/IFN-β axis

T. Shaker, E. Aronica, L. Carmant, 2019, Brain, Behavior, and Immunity.

IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells

C. Garlanda, A. Mantovani, L. Moretta, 2022, Journal for ImmunoTherapy of Cancer.

Anti‐tumor activity of cytokines against opportunistic vascular tumors in mice

C. Garlanda, A. Mantovani, F. Bussolino, 1996, International journal of cancer.

Plasma pentraxin-3 as a marker of bioincompatibility in hemodialysis patients.

C. Garlanda, G. Graziani, S. Badalamenti, 2012, Journal of nephrology.

Endogenous and exogenous pentraxin-3 limits postischemic acute and chronic kidney injury.

C. Garlanda, A. Mantovani, H. Anders, 2013, Kidney international.

Cytokines and Adhesion Molecules in Mesothelial Cell Pathophysiology

C. Garlanda, A. Mantovani, A. Mantovani, 1999 .

Corrigendum: Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation [Rheumatology, 55, (2016), (2220-2229)] doi:10.1093/rheumatology/kew325

L. Joosten, C. Garlanda, A. Mantovani, 2017 .

Regulatory pathways in inflammation.

Alberto Mantovani, Cecilia Garlanda, C. Garlanda, 2007, Autoimmunity reviews.

Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility.

C. Garlanda, A. Mantovani, A. Bastone, 2005, Annual review of immunology.

PTX3, a humoral pattern recognition molecule at the interface between microbe and matrix recognition.

C. Garlanda, A. Mantovani, A. Doni, 2016, Current opinion in immunology.

SARS-CoV-2–associated ssRNAs activate inflammation and immunity via TLR7/8

C. Garlanda, A. Mantovani, S. Sozzani, 2021, bioRxiv.

Long pentraxin PTX3 is associated with mortality and disease severity in severe Leptospirosis.

C. Garlanda, A. Mantovani, E. V. van Gorp, 2009, The Journal of infection.

An integrated view of humoral innate immunity: pentraxins as a paradigm.

C. Garlanda, A. Mantovani, A. Doni, 2010, Annual review of immunology.

The Yin Yang of Cancer Related Inflammation

P. Allavena, C. Garlanda, A. Sica, 2011 .

Tumor-associated myeloid cells: diversity and therapeutic targeting

P. Allavena, C. Garlanda, A. Mantovani, 2021, Cellular & Molecular Immunology.

Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation

Silvano Sozzani, Lorenzo Silengo, Emilio Hirsch, 2000 .

The Yin‐Yang of tumor‐associated macrophages in neoplastic progression and immune surveillance

P. Allavena, C. Garlanda, A. Sica, 2008, Immunological reviews.

Pentraxin 3 recruits complement factor H to protect against oxidative stress‐induced complement and inflammasome overactivation

C. Garlanda, J. Handa, K. Ebrahimi, 2016, The Journal of pathology.

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

C. Garlanda, A. Mantovani, A. García-Sastre, 2016, The Journal of experimental medicine.

Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors

C. Peano, C. Garlanda, A. Mantovani, 2019, Cell.

Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity.

C. Garlanda, A. Mantovani, C. Dinarello, 2019, Immunity.

The first case of COVID-19 treated with the complement C3 inhibitor AMY-101

John D. Lambris, John D Lambris, Markus Huber-Lang, 2020, Clinical Immunology.

The tumor microenvironment of colorectal cancer: stromal TLR-4 expression as a potential prognostic marker

C. Garlanda, D. Noonan, A. Albini, 2010, Journal of Translational Medicine.

Involvement of endothelial PECAM-1/CD31 in angiogenesis.

C. Garlanda, M. Burdick, R. Strieter, 1997, The American journal of pathology.

The long pentraxin PTX3 as a correlate of cancer-related inflammation and prognosis of malignancy in gliomas

C. Garlanda, A. Mantovani, M. Nebuloni, 2013, Journal of Neuroimmunology.

Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation.

P. Allavena, C. Garlanda, A. Sica, 2009, Human immunology.

Prognostic and diagnostic potential of local and circulating levels of pentraxin 3 in lung cancer patients

P. Allavena, C. Garlanda, A. Mantovani, 2016, International journal of cancer.

Progressive growth in immunodeficient mice and host cell recruitment by mouse endothelial cells transformed by polyoma middle-sized T antigen: implications for the pathogenesis of opportunistic vascular tumors.

C. Garlanda, A. Mantovani, F. Colotta, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Tumor associated macrophages and neutrophils in cancer.

C. Garlanda, A. Mantovani, I. Barajon, 2013, Immunobiology.

Tumor associated macrophages and neutrophils in tumor progression

C. Garlanda, A. Mantovani, G. Marone, 2013, Journal of cellular physiology.

Regulation of PTX3, a key component of humoral innate immunity in human dendritic cells: stimulation by IL‐10 and inhibition by IFN‐γ

C. Garlanda, A. Mantovani, G. Peri, 2006, Journal of leukocyte biology.

Defective dendritic cell migration and activation of adaptive immunity in PI3Kγ‐deficient mice

C. Garlanda, A. Mantovani, S. Bernasconi, 2004 .

Macropahge expression and prognostic significance of the long pentraxin PTX3 in COVID-19

C. Peano, S. Bonovas, C. Garlanda, 2020, medRxiv.

Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.

C. Garlanda, A. Mantovani, L. Pirola, 2000, Science.

Complexity and complementarity of outer membrane protein A recognition by cellular and humoral innate immunity receptors.

Pascale Jeannin, Barbara Bottazzi, Marco Presta, 2005, Immunity.

MiR-146b Mediates Endotoxin Tolerance in Human Phagocytes

C. Garlanda, M. Locati, M. Rubino, 2015, Mediators of inflammation.

Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR.

C. Garlanda, A. Mantovani, A. Benigni, 2003, European cytokine network.

Negative regulatory receptors of the IL-1 family.

C. Garlanda, A. Mantovani, F. Riva, 2013, Seminars in immunology.

Complement activation promoted by the lectin pathway mediates C3aR-dependent sarcoma progression and immunosuppression

C. Peano, C. Garlanda, A. Mantovani, 2021, Nature Cancer.

Sexual Dimorphism in Innate Immunity

C. Garlanda, K. Berthenet, S. Jaillon, 2019, Clinical Reviews in Allergy & Immunology.

Regulation of leukocyte recruitment by the long pentraxin PTX3

M. Gobbi, C. Garlanda, A. Mantovani, 2010, Nature Immunology.

IL1R8 Deficiency Drives Autoimmunity-Associated Lymphoma Development

C. Garlanda, A. Mantovani, H. Anders, 2019, Cancer Immunology Research.

The Long Pentraxin PTX3 as a Link Between Innate Immunity, Tissue Remodeling, and Cancer

C. Garlanda, A. Mantovani, A. Doni, 2019, Front. Immunol..

Tuning inflammation and immunity by the negative regulators IL‐1R2 and IL‐1R8

C. Garlanda, A. Mantovani, Domenico Supino, 2018, Immunological reviews.

Regulation of Immunity and Disease by the IL-1 Receptor Family Members IL-1R2 and IL-1R8

C. Garlanda, Domenico Supino, M. Molgora, 2018 .

The long pentraxin PTX3: A prototypical sensor of tissue injury and a regulator of homeostasis

C. Garlanda, A. Mantovani, P. Rovere-Querini, 2017, Immunological reviews.

Pentraxins in the activation and regulation of innate immunity

C. Garlanda, A. Mantovani, I. Barajon, 2016, Immunological reviews.

The pentraxins PTX3 and SAP in innate immunity, regulation of inflammation and tissue remodelling.

C. Garlanda, A. Mantovani, B. Bottazzi, 2016, Journal of hepatology.

The Dual Complexity of PTX3 in Health and Disease: A Balancing Act?

C. Garlanda, A. Mantovani, Elena Magrini, 2016, Trends in Molecular Medicine.

Regulatory Role of IL-1R8 in Immunity and Disease

C. Garlanda, A. Mantovani, I. Barajon, 2016, Front. Immunol..

TIR8/SIGIRR is an Interleukin-1 Receptor/Toll Like Receptor Family Member with Regulatory Functions in Inflammation and Immunity

C. Garlanda, A. Mantovani, M. Muzio, 2012, Front. Immun..

Inflammation-mediated promotion of invasion and metastasis

P. Allavena, C. Garlanda, A. Mantovani, 2010, Cancer and Metastasis Reviews.

Molecular pathways and targets in cancer-related inflammation

P. Allavena, C. Garlanda, A. Mantovani, 2010, Annals of medicine.

TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization.

C. Garlanda, A. Mantovani, H. Anders, 2009, Trends in immunology.

Increased susceptibility to colitis-associated cancer of mice lacking TIR8, an inhibitory member of the interleukin-1 receptor family.

C. Garlanda, A. Mantovani, E. Radaelli, 2007, Cancer research.

Long pentraxin‐3 as an epithelial–stromal fibroblast growth factor‐targeting inhibitor in prostate cancer

C. Garlanda, W. Vermi, R. Tardanico, 2013, The Journal of pathology.

PTX3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization

C. Garlanda, A. Mantovani, E. Hirsch, 2004, Development.

Negative Regulation of the IL-1 System by IL-1R2 and IL-1R8: Relevance in Pathophysiology and Disease

C. Garlanda, F. Riva, Domenico Supino, 2022, Frontiers in Immunology.

Macrophage diversity and polarization in atherosclerosis: a question of balance.

C. Garlanda, A. Mantovani, M. Locati, 2009, Arteriosclerosis, thrombosis, and vascular biology.

ATVB In Focus Monocyte Subsets and Their Relevance to Cardiovascular Diseases

C. Garlanda, M. Locati, 2009 .

A ‘Multiomic’ Approach of Saliva Metabolomics, Microbiota, and Serum Biomarkers to Assess the Need of Hospitalization in Coronavirus Disease 2019

Carl M. Sara, C. Peano, C. Garlanda, 2022, Gastro Hep Advances.

Neutrophils in innate and adaptive immunity

C. Garlanda, A. Mantovani, M. Cassatella, 2013, Seminars in Immunopathology.

Innate immunity, hemostasis and matrix remodeling: PTX3 as a link.

C. Garlanda, A. Mantovani, A. Doni, 2016, Seminars in immunology.

Gene and Protein Expression in Response to Different Growth Temperatures and Oxygen Availability in Burkholderia thailandensis

Olivia L. Champion, Pierluigi Mauri, Alessandro Pietrelli, 2014, PloS one.

Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.

L. Joosten, C. Garlanda, A. Mantovani, 2017, Rheumatology.

Treating experimental arthritis with the innate immune inhibitor interleukin-37 reduces joint and systemic inflammation.

L. Joosten, C. Garlanda, A. Mantovani, 2016, Rheumatology.

Role of Pentraxin 3 in Shaping Arthritogenic Alphaviral Disease: From Enhanced Viral Replication to Immunomodulation

K. Sheng, C. Garlanda, A. Mantovani, 2015, PLoS pathogens.

The “sweet” side of a long pentraxin: how glycosylation affects PTX3 functions in innate immunity and inflammation

C. Garlanda, A. Mantovani, P. Reading, 2013, Front. Immun..

Pentraxins in innate immunity: lessons from PTX3

C. Garlanda, A. Mantovani, B. Bottazzi, 2010, Cell and Tissue Research.

Pentraxin 3 protects from MCMV infection and reactivation through TLR sensing pathways leading to IRF3 activation.

C. Garlanda, A. Mantovani, F. Bistoni, 2006, Blood.

Decoys and Regulatory “Receptors” of the IL-1/Toll-Like Receptor Superfamily

C. Garlanda, A. Mantovani, F. Riva, 2013, Front. Immunol..

Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family.

C. Garlanda, A. Mantovani, E. Hirsch, 2004, Proceedings of the National Academy of Sciences of the United States of America.

SIGIRR/TIR-8 is an inhibitor of Toll-like receptor signaling in primary human cells and regulates inflammation in models of rheumatoid arthritis.

C. Garlanda, A. Mantovani, M. Feldmann, 2010, Arthritis and rheumatism.

IL-1R8: A molecular brake of anti-tumor and anti-viral activity of NK cells and ILC.

C. Garlanda, L. Moretta, A. Mantovani, 2023, Seminars in immunology.

Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll‐like receptors: the new entry TIR8/SIGIRR

C. Garlanda, A. Mantovani, M. Locati, 2004, Journal of leukocyte biology.

Interplay between Myeloid Cells and Humoral Innate Immunity

C. Garlanda, A. Mantovani, E. Bonavita, 2016, Microbiology spectrum.

Production of the soluble pattern recognition receptor PTX3 by myeloid, but not plasmacytoid, dendritic cells

Alberto Mantovani, Andrea Doni, Paola Allavena, 2003, European journal of immunology.

Role of Toll Interleukin-1 Receptor (IL-1R) 8, a Negative Regulator of IL-1R/Toll-Like Receptor Signaling, in Resistance to Acute Pseudomonas aeruginosa Lung Infection

C. Garlanda, A. Mantovani, S. Mantero, 2011, Infection and Immunity.

Evolution of the Pentraxin Family: The New Entry PTX4

C. Garlanda, A. Mantovani, M. Fabbri, 2010 .

The Toll-IL-1R Member Tir8/SIGIRR Negatively Regulates Adaptive Immunity against Kidney Grafts1

G. Remuzzi, C. Garlanda, A. Mantovani, 2009, The Journal of Immunology.

Humoral Innate Immunity and Acute-Phase Proteins

C. Garlanda, A. Mantovani, 2023, The New England journal of medicine.

Monocyte–macrophage polarization and recruitment pathways in the tumour microenvironment of B‐cell acute lymphoblastic leukaemia

P. Allavena, C. Garlanda, A. Mantovani, 2021, British journal of haematology.

IL-1R8 is a checkpoint in NK cells regulating anti-tumor and anti-viral activity

C. Garlanda, A. Mantovani, S. Jonjić, 2017, Nature.

An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode

C. Garlanda, A. Mantovani, E. Tremoli, 2015, The Journal of experimental medicine.

IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction

J. Whisstock, C. Garlanda, A. Mantovani, 2015, Nature Immunology.

Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology

C. Garlanda, S. Fumagalli, M. Sironi, 2021, Scientific Reports.

Serum amyloid P component is an essential element of resistance against Aspergillus fumigatus

John D Lambris, C. Garlanda, A. Mantovani, 2021, Nature Communications.

Complement as a target in COVID-19?

John D Lambris, C. Garlanda, J. Lambris, 2020, Nature Reviews Immunology.

Pathogen Recognition by the Long Pentraxin PTX3

C. Garlanda, A. Mantovani, M. Sironi, 2011, Journal of biomedicine & biotechnology.

Epigenetic regulation of the extrinsic oncosuppressor PTX3 gene in inflammation and cancer

C. Garlanda, A. Mantovani, M. Roncalli, 2017, Oncoimmunology.

Pentraxins: Multifunctional proteins at the interface of innate immunity and inflammation

C. Garlanda, A. Mantovani, B. Bottazzi, 2009, BioFactors.

Pattern recognition by pentraxins.

C. Garlanda, A. Mantovani, A. Agrawal, 2009, Advances in experimental medicine and biology.

Inflammation and neutrophil extracellular traps in cerebral cavernous malformation

C. Garlanda, A. Mantovani, M. Corada, 2022, Cellular and Molecular Life Sciences.

Purification through affinity chromatography and microsequencing.

C. Garlanda, 1999, Methods in molecular biology.

Humoral innate immunity at the crossroad between microbe and matrix recognition: The role of PTX3 in tissue damage

C. Garlanda, A. Mantovani, G. D'Amico, 2016, Seminars in Cell & Developmental Biology.

IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis

C. Garlanda, C. Dinarello, Soohyun Kim, 2014, PLoS pathogens.

Cotena Federica Moalli Sebastien Jaillon Livija Deban Alberto Mantovani The long pentraxin PTX 3 as a prototypic humoral pattern recognition receptor : interplay with cellular innate immunity

C. Garlanda, A. Mantovani, B. Bottazzi, 2008 .

Lack of the Long Pentraxin PTX3 Promotes Autoimmune Lung Disease but not Glomerulonephritis in Murine Systemic Lupus Erythematosus

C. Garlanda, A. Mantovani, H. Anders, 2011, PloS one.

Lack of Toll IL-1R8 Exacerbates Th17 Cell Responses in Fungal Infection1

L. Boon, C. Garlanda, A. Mantovani, 2008, The Journal of Immunology.

Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects

C. Garlanda, A. Mantovani, E. Menna, 2017, eLife.

Pentraxin 3 mediates neurogenesis and angiogenesis after cerebral ischaemia

C. Garlanda, Á. Dénes, E. Pinteaux, 2015, Journal of Neuroinflammation.

Pentraxins and atherosclerosis

C. Garlanda, A. Mantovani, R. Latini, 2012 .

Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1‐integrin

C. Garlanda, A. Mantovani, E. Menna, 2018, The EMBO journal.

The Long Pentraxin PTX3 as a Humoral Innate Immunity Functional Player and Biomarker of Infections and Sepsis

C. Garlanda, A. Mantovani, B. Bottazzi, 2019, Front. Immunol..

Pentraxins in the Orchestration of Defense and Tissue Repair during the Acute Phase Response

C. Garlanda, A. Mantovani, B. Bottazzi, 2017 .

Fluid phase recognition molecules in neutrophil-dependent immune responses.

C. Garlanda, A. Mantovani, I. Barajon, 2016, Seminars in immunology.

The Long Pentraxin PTX3 as a Key Component of Humoral Innate Immunity and a Candidate Diagnostic for Inflammatory Diseases

C. Garlanda, A. Mantovani, I. Laface, 2014, International Archives of Allergy and Immunology.

The long pentraxin PTX3: a paradigm for humoral pattern recognition molecules

C. Garlanda, A. Mantovani, B. Bottazzi, 2013, Annals of the New York Academy of Sciences.

PTX3 as a paradigm for the interaction of pentraxins with the complement system.

C. Garlanda, A. Mantovani, I. Barajon, 2013, Seminars in immunology.

sensing pathways leading to IRF3 activation Pentraxin 3 protects from MCMV infection and reactivation through TLR

C. Garlanda, A. Mantovani, F. Bistoni, 2013 .

Interactions of the humoral pattern recognition molecule PTX3 with the complement system.

C. Garlanda, A. Mantovani, S. Meri, 2012, Immunobiology.

Pentraxins in humoral innate immunity.

C. Garlanda, A. Mantovani, B. Bottazzi, 2012, Advances in experimental medicine and biology.

The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa

C. Garlanda, A. Mantovani, S. Mantero, 2011, The Journal of Immunology.

Novel Players in Female Fertility: The Long Pentraxin PTX3 and the Chemokine Decoy Receptor D6

C. Garlanda, M. Locati, M. Nebuloni, 2011 .

Role of complement and Fc{gamma} receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus.

C. Garlanda, A. Mantovani, L. Romani, 2010, Blood.

Serum levels of soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) and pentraxin 3 (PTX3) as markers of infection in febrile patients with systemic lupus erythematosus.

C. Garlanda, J. A. Park, A. Cotena, 2009, Clinical and experimental rheumatology.

Follicular Fuid Levels of the Long Pentraxin PTX3

C. Garlanda, A. Mantovani, G. Pardi, 2006, The Journal of the Society for Gynecologic Investigation: JSGI.

Serum levels of soluble triggering receptor expressed on myeloid cells-1 ( sTREM-1 ) and pentraxin 3 ( PTX 3 ) as markers of infection in febrile patients with systemic lupus erythematosus

C. Garlanda, J. A. Park, A. Cotena, 2006 .

Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance

L. Joosten, E. Eisenmesser, C. Garlanda, 2017, Proceedings of the National Academy of Sciences.

Complementary Roles of Short and Long Pentraxins in the Complement-Mediated Immune Response to Aspergillus fumigatus Infections

C. Garlanda, A. Mantovani, M. Erreni, 2021, Frontiers in Immunology.

Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation.

Andrea Carpentieri, Alberto Mantovani, Antonio Bastone, 2006, Biochemistry.

The Long Pentraxin PTX3 Controls Klebsiella Pneumoniae Severe Infection

C. Recordati, C. Garlanda, A. Mantovani, 2021, Frontiers in Immunology.

Mesenchymal Stromal Cell-Derived PTX3 Promotes Wound Healing via Fibrin Remodeling.

C. Garlanda, A. Mantovani, F. Pasqualini, 2016, The Journal of investigative dermatology.

Endothelial Cells: Immunological Aspects

C. Garlanda, A. Mantovani, 2001 .

Pentraxin 3 promotes long-term cerebral blood flow recovery, angiogenesis, and neuronal survival after stroke

C. Garlanda, S. Allan, E. Pinteaux, 2018, Journal of Molecular Medicine.

Prototypic Long Pentraxin PTX3 Is Present in Breast Milk, Spreads in Tissues, and Protects Neonate Mice from Pseudomonas aeruginosa Lung Infection

C. Garlanda, A. Mantovani, G. Mancuso, 2013, The Journal of Immunology.

PTX3 predicts severe disease in febrile patients at the emergency department.

P. Reitsma, C. Garlanda, A. Mantovani, 2010, The Journal of infection.

Summary PTX 3 plays a key role in the organization of the cumulus oophorus extracellular matrix and in in vivo fertilization

C. Garlanda, A. Mantovani, E. Hirsch, 2004 .

The expression pattern of TIR8 is conserved among vertebrates.

C. Garlanda, A. Mantovani, L. Turin, 2009, Veterinary immunology and immunopathology.

Expression and function of IL-1R8 (TIR8/SIGIRR): a regulatory member of the IL-1 receptor family in platelets.

C. Garlanda, A. Mantovani, A. Anselmo, 2016, Cardiovascular research.

Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy

John D Lambris, B. Nilsson, S. Iacobelli, 2020, Clinical Immunology.

Amyotrophic lateral sclerosis transcriptomics reveals immunological effects of low-dose interleukin-2

A. Al-Chalabi, P. Leigh, C. Garlanda, 2021, Brain communications.

Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19

C. Peano, S. Bonovas, C. Garlanda, 2020, Nature Immunology.

Glucose availability enhances lipopolysaccharide production and immunogenicity in the opportunistic pathogen Acinetobacter baumannii.

Alessandro Pietrelli, Clarissa Consolandi, Clelia Peano, 2016, Future microbiology.

Clearance of Cell Remnants and Regeneration of Injured Muscle Depend on Soluble Pattern Recognition Receptor PTX3

C. Garlanda, A. Mantovani, A. Castiglioni, 2016, Molecular medicine.

Circulating biomarkers and cardiac function over 3 years after chemotherapy with anthracyclines: the ICOS‐ONE trial

G. Condorelli, C. Garlanda, A. Mantovani, 2020, ESC heart failure.

The Long Pentraxin PTX3, a Soluble Pattern Recognition Receptor Involved in Innate Immunity,Inflammation and Female Fertility

C. Garlanda, A. Mantovani, A. Doni, 2006 .

Tumor-associated Macrophages: Cytokine Regulation and Therapeutic Implications

P. Allavena, C. Garlanda, A. Mantovani, 1993 .

Cytokine Regulation of Tumor-Associated Macrophages: Therapeutic Implications

P. Allavena, C. Garlanda, A. Mantovani, 1993 .

A PTX3/LDH/CRP signature correlates with lung injury CTs scan severity and disease progression in paucisymptomatic COVID-19

C. Garlanda, R. Leone, M. Sironi, 2021, medRxiv.

Size-advantage of monovalent nanobodies against the macrophage mannose receptor for deep tumor penetration and tumor-associated macrophage targeting

P. Allavena, C. Garlanda, A. Mantovani, 2023, Theranostics.

The second institution in the author affiliations was published incorrectly. In addition, the author list was published incorrectly. The corrected author list and affiliation list are shown below.

Domenico Cianflone, Barbara Bottazzi, San Raffaele, 2011 .

Pentraxin 3 Inhibits Complement-driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis

John D Lambris, C. Garlanda, A. Mantovani, 2022, American journal of respiratory and critical care medicine.

Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium.

C. Garlanda, A. Mantovani, M. Lampugnani, 1994, European journal of cell biology.

The long pentraxin PTX3 binds to apoptotic cells and regulates their clearance by antigen-presenting dendritic cells.

C. Garlanda, A. Mantovani, C. Rugarli, 2000, Blood.

PTX3 orchestrates tissue repair

C. Garlanda, A. Mantovani, A. Doni, 2015, Oncotarget.

A general strategy for isolation of endothelial cells from murine tissues. Characterization of two endothelial cell lines from the murine lung and subcutaneous sponge implants.

C. Garlanda, A. Mantovani, F. Breviario, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Lack of SIGIRR/TIR8 aggravates hydrocarbon oil-induced systemic lupus nephritis

C. Garlanda, A. Mantovani, H. Anders, 2010 .

Single Immunoglobulin Interleukin-1 Receptor-Related Molecule Impairs Host Defense during Pneumonia and Sepsis Caused by Streptococcus Pneumoniae

T. van der Poll, C. Garlanda, A. Mantovani, 2014, Journal of Innate Immunity.

Pentraxin 3 deficiency protects from the metabolic inflammation associated to diet-induced obesity.

C. Garlanda, A. Mantovani, M. Sironi, 2019, Cardiovascular research.

The interleukin-1 family: back to the future.

C. Garlanda, A. Mantovani, C. Dinarello, 2013, Immunity.

Clearance of Cell Remnants and Regeneration of Injured Muscle Depend on Soluble Pattern Recognition Receptor PTX3

C. Garlanda, A. Mantovani, A. Castiglioni, 2016, Molecular medicine.

Cytokine decoy and scavenger receptors as key regulators of immunity and inflammation.

C. Garlanda, A. Mantovani, R. Bonecchi, 2016, Cytokine.

TIR8/SIGIRR: an IL-1R/TLR family member with regulatory functions in inflammation and T cell polarization.

C. Garlanda, A. Mantovani, H. Anders, 2009, Trends in immunology.

Macrophage diversity and polarization in atherosclerosis: a question of balance.

C. Garlanda, A. Mantovani, M. Locati, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Reduced tumorigenicity and augmented leukocyte infiltration after monocyte chemotactic protein-3 (MCP-3) gene transfer: perivascular accumulation of dendritic cells in peritumoral tissue and neutrophil recruitment within the tumor.

C. Garlanda, A. Mantovani, A. Minty, 1998, Journal of immunology.

A Multilayered Imaging and Microfluidics Approach for Evaluating the Effect of Fibrinolysis in Staphylococcus aureus Biofilm Formation

C. Garlanda, M. Erreni, Raffaella Parente, 2023, Pathogens.

The Yin‐Yang of tumor‐associated macrophages in neoplastic progression and immune surveillance

P. Allavena, C. Garlanda, A. Sica, 2008, Immunological reviews.

Molecular pathways and targets in cancer-related inflammation

P. Allavena, C. Garlanda, A. Mantovani, 2010, Annals of medicine.

P. Allavena, C. Garlanda, A. Sica, 2009, Carcinogenesis.

Pathways connecting inflammation and cancer.

P. Allavena, C. Garlanda, M. Borrello, 2008, Current opinion in genetics & development.

IL‐1 and IL‐1 regulatory pathways in cancer progression and therapy

C. Garlanda, A. Mantovani, I. Barajon, 2018, Immunological reviews.

Interleukin 37 reverses the metabolic cost of inflammation, increases oxidative respiration, and improves exercise tolerance

L. Joosten, E. Eisenmesser, C. Garlanda, 2017, Proceedings of the National Academy of Sciences.

PTX3 Is an Extrinsic Oncosuppressor Regulating Complement-Dependent Inflammation in Cancer

John D Lambris, C. Garlanda, A. Mantovani, 2015, Cell.

Evolution of the Pentraxin Family: The New Entry PTX4

C. Garlanda, M. Fabbri, M. Nebuloni, 2010, The Journal of Immunology.

Regulation of leukocyte recruitment by the long pentraxin PTX3

M. Gobbi, C. Garlanda, A. Mantovani, 2010, Nature Immunology.

Vascular pentraxin 3 controls arterial thrombosis by targeting collagen and fibrinogen induced platelets aggregation

C. Garlanda, A. Mantovani, E. Tremoli, 2016, Biochimica et biophysica acta.

An Alternative Role of C1q in Cell Migration and Tissue Remodeling: Contribution to Trophoblast Invasion and Placental Development

C. Garlanda, C. Tripodo, A. Santoni, 2010, The Journal of Immunology.

Defective dendritic cell migration and activation of adaptive immunity in PI3Kgamma-deficient mice.

C. Garlanda, W. Luini, M. Sironi, 2004, The EMBO journal.

Nonredundant role of CCRL2 in lung dendritic cell trafficking.

C. Garlanda, E. Hirsch, S. Sozzani, 2010, Blood.

The long pentraxin PTX3 as a correlate of cancer-related inflammation and prognosis of malignancy in gliomas

C. Garlanda, M. Nebuloni, S. Gaini, 2013, Journal of Neuroimmunology.

The Yin Yang of Complement and Cancer.

C. Garlanda, Elena Magrini, Seppo Meri, 2023, Cancer immunology research.