J. Round

发表

A microbial symbiosis factor prevents intestinal inflammatory disease

S. Mazmanian, J. Round, D. Kasper, 2008, Nature.

The gut microbiota shapes intestinal immune responses during health and disease

S. Mazmanian, J. Round, Sarkis K. Mazmanian, 2009, Nature Reviews Immunology.

Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells

Min Zhang, J. Round, S. Schoenberger, 2005, The Journal of experimental medicine.

Reactivation of latent HIV-1 in central memory CD4+ T cells through TLR-1/2 stimulation

J. Round, M. Lichterfeld, D. Margolis, 2013, Retrovirology.

Immunology: You Remind Me of a Microbe I Know

J. Round, Raymond Soto, R. Soto, 2016, Current Biology.

MHC variation sculpts individualized microbial communities that control susceptibility to enteric infection

Ryan M. O’Connell, W. Potts, N. Ajami, 2015, Nature Communications.

Phage display of environmental protein toxins and virulence factors reveals the prevalence, persistence, and genetics of antibody responses.

Priya D. Duggal, A. Mammen, I. Ruczinski, 2022, Immunity.

Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease

Ryan M. O’Connell, M. Bronner, J. Round, 2019, PLoS genetics.

CD45 Signals outside of Lipid Rafts to Promote ERK Activation, Synaptic Raft Clustering, and IL-2 Production1

Min Zhang, J. Round, M. Miceli, 2005, The Journal of Immunology.

Clustering , and IL-2 Production Promote ERK Activation , Synaptic Raft CD 45 Signals outside of Lipid Rafts

Min Zhang, J. Round, M. Miceli, 2005 .

The DNA Architectural Protein HMGB1 Facilitates RTA-Mediated Viral Gene Expression in Gamma-2 Herpesviruses

Jie Liang, Y. Turpaz, R. Sun, 2004, Journal of Virology.

MicroRNA-146a constrains multiple parameters of intestinal immunity and increases susceptibility to DSS colitis

Ryan M. O’Connell, Noah C. Welker, Daniel Patrick Smith, 2015, Oncotarget.

Fiber Puts Lactobacillus to SLEep.

J. Round, Tyson R. Chiaro, 2019, Cell host & microbe.

The gut microbiota shapes intestinal immune responses during health and disease

S. Mazmanian, J. Round, 2009, Nature Reviews Immunology.

Immunology: How the Microbiota Digests Bile to Protect against Viral Infection

J. Round, Kendra A. Klag, 2020, Current Biology.

Altered immunity of laboratory mice in the natural environment is associated with fungal colonization

Kelly V. Ruggles, P. Loke, J. Round, 2019, bioRxiv.

Do antibodies select a healthy microbiota?

J. Round, J. Kubinak, 2016, Nature Reviews Immunology.

Friends in Low Places: Intestinal Commensals Limit Colitis through Molecular Mimicry

J. Round, D. Brown, 2017, Cell.

Human differentiated eosinophils release IL-13 in response to IL-33 stimulation

J. Round, L. Qiang, S. Dougan, 2022, Frontiers in Immunology.

Communication Between the Microbiota and Mammalian Immunity.

J. Round, Kyla S. Ost, 2018, Annual review of microbiology.

Models and Tools for Investigating Eosinophilic Esophagitis at the Bench

J. Round, J. Garber, K. Peterson, 2022, Frontiers in Immunology.

FLT 3-ITD-induced myeloproliferative disease through inhibition of the interferon response Short Title : miR-155 promotes FLT 3-ITD-induced myeloproliferative disease

Ryan M. O’Connell, J. Round, M. Deininger, 2017 .

Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development.

Ryan M. O’Connell, J. Round, J. Rutter, 2020, Cell reports.

Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota

S. Mazmanian, J. Round, Sarkis K. Mazmanian, 2010, Proceedings of the National Academy of Sciences.

BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass.

J. Round, R. Parthasarathy, S. Remington, 2022, Cell metabolism.

Wild herbivorous mammals (genus Neotoma) host a diverse but transient assemblage of fungi

J. Round, M. Dearing, R. Greenhalgh, 2022, Symbiosis.

The Toll-Like Receptor 2 Pathway Establishes Colonization by a Commensal of the Human Microbiota

T. Chatila, S. Mazmanian, J. Round, 2011, Science.

No small matter: emerging roles for exosomal miRNAs in the immune system

Ryan M. O’Connell, J. Round, Ryan M. O'Connell, 2021, The FEBS journal.

Immune-bacteriophage interactions in inflammatory bowel diseases.

J. Round, L. Gogokhia, 2021, Current opinion in virology.

A Few Good Commensals: Gut Microbes Use IFN-γ to Fight Salmonella.

J. Round, Kyla S. Ost, 2017, Immunity.

CD11c+ myeloid cell exosomes reduce intestinal inflammation during colitis

Ryan M. O’Connell, J. Round, Allison M. Weis, 2022, JCI insight.

Original Differences in the gut microbiome by physical activity and BMI among colorectal cancer patients

N. Habermann, M. Bronner, J. Round, 2022 .

Causal effects of the microbiota on immune-mediated diseases

J. Round, Noah W. Palm, 2018, Science Immunology.

MyD88 signaling in T cells directs IgA-mediated control of the microbiota to promote health.

Ryan M. O’Connell, J. Round, W. Stephens, 2015, Cell host & microbe.

Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-κB transcription factors

Min Zhang, J. Round, P. Mittelstadt, 2007, Nature Immunology.

Gut microbiota: a new way to take your vitamins

J. Round, J. C. Gomes-Neto, 2018, Nature Reviews Gastroenterology & Hepatology.

T cell–mediated regulation of the microbiota protects against obesity

Ryan M. O’Connell, J. Round, S. Boudina, 2019, Science.

Defining dysbiosis and its influence on host immunity and disease

J. Round, June L Round, C. Petersen, 2014, Cellular microbiology.

Adaptive immunity induces mutualism between commensal eukaryotes

Ryan M. O’Connell, J. Round, K. Christensen, 2021, Nature.

SnapShot: Microbiota effects on host physiology

J. Round, J. Hill, 2021, Cell.

A member of the gut mycobiota modulates host purine metabolism exacerbating colitis in mice

Ryan M. O’Connell, D. Stillman, J. Round, 2017, Science Translational Medicine.

Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

Ryan M. O’Connell, J. Round, Allison M. Weis, 2021, Cell reports.

Expansion of Bacteriophages Is Linked to Aggravated Intestinal Inflammation and Colitis.

Ryan M. O’Connell, N. Ajami, J. Round, 2019, Cell host & microbe.

Does MHC heterozygosity influence microbiota form and function?

J. Round, W. Stephens, J. Kubinak, 2019, PloS one.

T Cell–Expressed microRNA-155 Reduces Lifespan in a Mouse Model of Age-Related Chronic Inflammation

Ryan M. O’Connell, J. Round, J. Rutter, 2020, The Journal of Immunology.

Antitumor immunity is defective in T cell–specific microRNA-155–deficient mice and is rescued by immune checkpoint blockade

Ryan M. O’Connell, J. Round, Margaret Alexander, 2017, The Journal of Biological Chemistry.

T cell expressed miR-155 promotes antitumor immunity

Ryan M. O’Connell, J. Round, Margaret Alexander, 2017 .

Molecular patterns from a human gut-derived Lactobacillus strain suppress pathogenic infiltration of leukocytes into the central nervous system

D. J. Doty, J. Round, J. Libbey, 2020, Journal of neuroinflammation.

Isolation and characterization of the activated B-cell factor 1 homolog in Caenorhabditis elegans.

L. Nguyen, J. Round, M. Funes-Duran, 2001, Nucleic acids research.

miR-155 promotes FLT3-ITD-induced myeloproliferative disease through inhibition of the interferon response.

Ryan M. O’Connell, J. Round, M. Deininger, 2017, Blood.

A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages

Ryan M. O’Connell, J. Round, W. Tang, 2021, Nature Communications.

Epistasis between microRNAs 155 and 146a during T cell-mediated antitumor immunity.

Ryan M. O’Connell, D. Baltimore, J. Round, 2012, Cell reports.

Microbiota-Immune Interactions Regulate Metabolic Disease

J. Round, Kendra A. Klag, 2021, The Journal of Immunology.

MicroRNAs and the regulation of intestinal homeostasis

Ryan M. O’Connell, J. Round, M. Runtsch, 2014, Front. Genet..

Thymic development of gut-microbiota-specific T cells

J. Round, R. Longman, T. Egawa, 2021, Nature.

Microbiota-antibody interactions that regulate gut homeostasis.

J. Round, Allison M. Weis, 2021, Cell host & microbe.

The microbiota protects from viral-induced neurologic damage through microglia-intrinsic TLR signaling

Ryan M. O’Connell, J. Round, R. Fujinami, 2019, eLife.

Commensal regulation of T cell survival through Erdr1

J. Round, Allison M. Weis, R. Soto, 2018, Gut microbes.

Variations in diet cause alterations in microbiota and metabolites that follow changes in disease severity in a multiple sclerosis model.

D. J. Doty, J. Round, M. Cusick, 2018, Beneficial microbes.

Microbiota promotes systemic T-cell survival through suppression of an apoptotic factor

Ryan M. O’Connell, J. Round, R. Fujinami, 2017, Proceedings of the National Academy of Sciences.

From Fly to Human: Understanding How Commensal Microorganisms Influence Host Immunity and Health

J. Round, 2013 .

Fusobacterium nucleatum and Clinicopathologic Features of Colorectal Cancer: Results From the ColoCare Study.

Eric A. Swanson, P. Schrotz-King, C. Ulrich, 2021, Clinical colorectal cancer.

MicroRNA-155 coordinates the immunological landscape within murine melanoma and correlates with immunity in human cancers.

Ryan M. O’Connell, J. Round, Matthew A. Williams, 2019, JCI insight.

A microbiota membrane disrupter disseminates to the pancreas and increases β-cell mass

J. Round, R. Parthasarathy, S. Remington, 2022, bioRxiv.

Differences in the gut microbiome by physical activity and BMI among colorectal cancer patients.

N. Habermann, P. Schrotz-King, M. Bronner, 2022, American journal of cancer research.

Microbiota The amalgam of microorganisms that make up a complex and diverse community living within a given anatomical niche

S. Mazmanian, J. Round, 2009 .

Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

Ryan M. O’Connell, J. Round, T. Tolmachova, 2015, Nature Communications.

The gut microbiome shapes intestinal immune responses during health and disease

S. Mazmanian, J. Round, Sarkis K. Mazmanian, 2014 .

MicroRNA-155 promotes autoimmune inflammation by enhancing inflammatory T cell development.

Ryan M. O’Connell, D. Baltimore, A. Chaudhuri, 2010, Immunity.

Innate-like lymphocytes in intestinal infections

J. Round, D. Leung, M. S. Bennett, 2015, Current opinion in infectious diseases.

Rab27-Dependent Exosome Production Inhibits Chronic Inflammation and Enables Acute Responses to Inflammatory Stimuli

Ryan M. O’Connell, J. Round, T. Tolmachova, 2017, The Journal of Immunology.

miR-155 promotes T follicular helper cell accumulation during chronic, low-grade inflammation.

Margaret Alexander, Thomas Möller, Ryan M. O’Connell, 2014, Immunity.

IL-10 Deficiency Reveals a Role for TLR2-Dependent Bystander Activation of T Cells in Lyme Arthritis

J. Zachary, J. Round, Matthew A. Williams, 2018, The Journal of Immunology.

Coordination of tolerogenic immune responses by the commensal microbiota.

Ryan M. O’Connell, S. Mazmanian, J. Round, 2010, Journal of autoimmunity.

The effects of diet on the severity of central nervous system disease: One part of lab-to-lab variability.

D. J. Doty, J. Round, M. Cusick, 2016, Nutrition.

Prevalence, persistence, and genetics of antibody responses to protein toxins and virulence factors

A. Mammen, Uri Laserson, J. Round, 2021, bioRxiv.

Erratum: The gut microbiota shapes intestinal immune responses during health and disease (Nature Reviews Immunology (2009) 9 (313-323))

S. Mazmanian, J. Round, 2009 .

MicroRNA-155 Confers Encephalogenic Potential to Th17 Cells by Promoting Effector Gene Expression

Ryan M. O’Connell, A. Chaudhuri, J. Round, 2013, The Journal of Immunology.

Characterization of In Vivo Dlg1 Deletion on T Cell Development and Function

R. Huganir, J. Round, K. Takamiya, 2012, PloS one.

Acute Responses to Inflammatory Stimuli Inhibits Chronic Inflammation and Enables Rab 27-Dependent Exosome Production

J. Round, T. Tolmachova, Margaret Alexander, 2017 .

Round Commensal of the Human Microbiota The Toll-Like Receptor 2 Pathway Establishes Colonization by a

T. Chatila, S. Mazmanian, J. Round, 2011 .

Clec12a tempers inflammation while restricting expansion of a colitogenic commensal

Ryan M. O’Connell, J. Round, Tyson R. Chiaro, 2023, bioRxiv.

Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth

Ryan M. O’Connell, J. Round, D. Rao, 2016, PloS one.

Dual colorimetric and fluorogenic probes for visualizing tyrosine phosphatase activity.

J. Round, K. Ullman, Colin W. Russell, 2017, Chemical communications.

Universal Principled Review: A Community-Driven Method to Improve Peer Review

Greg Barton, Matt Williams, Sebastian Amigorena, 2019, Cell.

Toll-Like Receptors Promote Mutually Beneficial Commensal-Host Interactions

J. Round, J. Kubinak, 2012, PLoS pathogens.

Associations of combined physical activity and body mass index groups with colorectal cancer survival outcomes

J. Round, D. Shibata, E. Siegel, 2023, BMC Cancer.

IgA targets the troublemakers.

J. Round, W. Stephens, 2014, Cell host & microbe.

Characterization of a basic helix-loop-helix protein, ABF-1: nuclear localization, transcriptional properties, and interaction with Id-2.

J. Round, M. Funes-Duran, C. Vierra, 2001, DNA and cell biology.

Commensal fungi in intestinal health and disease

J. Round, Kyla S. Ost, 2023, Nature Reviews Gastroenterology & Hepatology.

MicroRNA-155 Plays Selective Cell-Intrinsic Roles in Brain-Infiltrating Immune Cell Populations during Neuroinflammation.

Ryan M. O’Connell, J. Round, R. Fujinami, 2023, Journal of Immunology.

Bacteriophage-Bacteria Interactions in the Gut: From Invertebrates to Mammals.

J. Round, Robert Brzozowski, Dominick R. Faith, 2021, Annual review of virology.

MyD88 signaling in T cells directs IgA-mediated control of the microbiota to promote health.

J. Round, W. Stephens, C. Petersen, 2015, Cell host & microbe.

Reactivation of latent HIV-1 in central memory CD4+ T cells through TLR-1/2 stimulation

J. Round, M. Lichterfeld, D. Margolis, 2013, Retrovirology.

Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells

Min Zhang, J. Round, S. Schoenberger, 2005, Journal of Experimental Medicine.

Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn

I. Ruczinski, J. Round, Kathleen C. Waugh, 2023, bioRxiv.