S. Vacher

发表

Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.

D. Bergstrom, Weidong Zhang, C. Dib, 2015, Cancer research.

Genomic Instability Signature of Palindromic Non-Coding Somatic Mutations in Bladder Cancer

Y. Allory, S. Vacher, I. Bièche, 2020, Cancers.

PIK3R1 underexpression is an independent prognostic marker in breast cancer

Etienne Rouleau, Rosette Lidereau, Didier Meseure, 2013, BMC Cancer.

Gene Expression Profiling Reveals New Aspects of PIK3CA Mutation in ERalpha-Positive Breast Cancer: Major Implication of the Wnt Signaling Pathway

Rosette Lidereau, S. Vacher, I. Bièche, 2010, PloS one.

Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon

Carsten Janke, Didier Meseure, Wulfran Cacheux, 2014, The EMBO journal.

Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon

S. Vacher, W. Cacheux, I. Bièche, 2014 .

miRNA expression profiling of inflammatory breast cancer identifies a 5‐miRNA signature predictive of breast tumor aggressiveness

Rosette Lidereau, S. Vacher, I. Bièche, 2013, International journal of cancer.

Valproic Acid Decreases Endothelial Colony Forming Cells Differentiation and Induces Endothelial-to-Mesenchymal Transition-like Process

S. Vacher, I. Bièche, M. Ratajczak, 2020, Stem Cell Reviews and Reports.

Immune gene expression in head and neck squamous cell carcinoma patients.

O. Mariani, J. Klijanienko, S. Vacher, 2019, European journal of cancer.

HRAS is a therapeutic target in malignant chemo-resistant adenomyoepithelioma of the breast

A. Vincent-Salomon, S. Vacher, S. Château-Joubert, 2021, Journal of Hematology & Oncology.

A large collection of integrated genomically characterized patient‐derived xenografts highlighting the heterogeneity of triple‐negative breast cancer

A. Vincent-Salomon, S. Vacher, S. Château-Joubert, 2019, International journal of cancer.

MicroRNA Expression Profiling of Inflammatory Breast Cancer.

S. Vacher, I. Bièche, R. Lidereau, 2009 .

microRNA expression profile in a large series of bladder tumors: Identification of a 3‐miRNA signature associated with aggressiveness of muscle‐invasive bladder cancer

S. Vacher, I. Bièche, S. Tozlu, 2013, International journal of cancer.

Harmonisation of multi-centre real-time reverse-transcribed PCR results of a candidate prognostic marker in breast cancer: an EU-FP6 supported study of members of the EORTC - PathoBiology Group.

A. Sieuwerts, J. Martens, P. Span, 2009, European journal of cancer.

MMP2 as an independent prognostic stratifier in oral cavity cancers

O. Mariani, J. Klijanienko, S. Vacher, 2020, Oncoimmunology.

MMP2 as an independent prognostic stratifier in oral cavity cancers

O. Mariani, J. Klijanienko, S. Vacher, 2019, bioRxiv.

Comprehensive genomic profiling of head and neck squamous cell carcinoma reveals FGFR1 amplifications and tumour genomic alterations burden as prognostic biomarkers of survival.

O. Mariani, J. Klijanienko, S. Vacher, 2018, European journal of cancer.

Genome-wide DNA methylation profiling of CpG islands in breast cancer identifies novel genes associated with tumorigenicity.

C. Ricketts, S. Vacher, I. Bièche, 2011, Cancer research.

IL-1β produced by aggressive breast cancer cells is one of the factors that dictate their interactions with mesenchymal stem cells through chemokine production

S. Vacher, I. Bièche, C. Jorgensen, 2015, Oncotarget.

A Molecular Predictor Reassesses Classification of Human Grade II/III Gliomas

T. Rème, H. Duffau, S. Vacher, 2013, PloS one.

Alteration of splicing factors’ expression during liver disease progression: impact on hepatocellular carcinoma outcome

S. Vacher, I. Bièche, I. Chemin, 2019, Hepatology International.

Capecitabine Efficacy Is Correlated with TYMP and RB1 Expression in PDX Established from Triple-Negative Breast Cancers

M. Piccart, A. Vincent-Salomon, S. Vacher, 2018, Clinical Cancer Research.

Human papilloma virus integration sites and genomic signatures in head and neck squamous cell carcinoma

A. Nicolas, R. Rouzier, J. Klijanienko, 2022, Molecular oncology.

The trimeric coiled‐coil HSBP1 protein promotes WASH complex assembly at centrosomes

A. Gautreau, R. Guérois, S. Vacher, 2018, The EMBO journal.

Correlation between messenger RNA expression and protein expression of immune checkpoint-associated molecules in bladder urothelial carcinoma: A retrospective study.

S. Vacher, I. Bièche, M. Sibony, 2017, Urologic oncology.

High Positive Correlations between ANRIL and p16-CDKN2A/p15-CDKN2B/p14-ARF Gene Cluster Overexpression in Multi-Tumor Types Suggest Deregulated Activation of an ANRIL–ARF Bidirectional Promoter

Y. Allory, S. Vacher, W. Cacheux, 2019, Non-coding RNA.

Rational testing for gene fusion in colorectal cancer: MSI and RAS-BRAF wild-type metastatic colorectal cancer as target population for systematic screening.

Y. Allory, S. Vacher, I. Bièche, 2022, European journal of cancer.

Interleukin-8 Receptors CXCR1 and CXCR2 Are Not Expressed by Endothelial Colony-forming Cells

S. Vacher, I. Bièche, P. Gaussem, 2020, Stem Cell Reviews and Reports.

Inhibition of mTOR downregulates expression of DNA repair proteins and is highly efficient against BRCA2-mutated breast cancer in combination to PARP inhibition

S. Vacher, S. Château-Joubert, I. Bièche, 2018, Oncotarget.

Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma

S. Vacher, I. Bièche, C. Bousquet, 2022, The Journal of pathology.

Prognostic Value of Fusobacterium nucleatum after Abdominoperineal Resection for Anal Squamous Cell Carcinoma

N. Rioux-Leclercq, S. Vacher, A. Lièvre, 2022, Cancers.

CYFIP2-containing WAVE complexes inhibit cell migration by a competition mechanism

A. Gautreau, R. Guérois, S. Vacher, 2020 .

BCG therapy downregulates HLA-I on malignant cells to subvert antitumor immune responses in bladder cancer

T. Tan, J. Thiery, L. Zitvogel, 2022, The Journal of clinical investigation.

In vivo efficacy assessment of the CDK4/6 inhibitor palbociclib and the PLK1 inhibitor volasertib in human chordoma xenografts

S. Vacher, S. Roman-Roman, I. Bièche, 2022, Frontiers in Oncology.

Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin II AT2 receptor-interacting proteins, ATIP.

P. Pineau, S. Vacher, I. Bièche, 2006, Gene.

Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant

S. Vacher, I. Bièche, I. Treilleux, 2020, Breast cancer research : BCR.

Combination of Carboplatin and Bevacizumab Is an Efficient Therapeutic Approach in Retinoblastoma Patient-Derived Xenografts.

S. Vacher, A. Nicolas, I. Bièche, 2016, Investigative ophthalmology & visual science.

Cytidine deaminase activity increases in the blood of breast cancer patients

S. Vacher, I. Bièche, D. Stoppa-Lyonnet, 2022, Scientific Reports.

p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer

A. Vincent-Salomon, S. Vacher, I. Bièche, 2016, Oncogene.

Reverse transcriptase-PCR quantification of mRNA levels from cytochrome (CYP)1, CYP2 and CYP3 families in 22 different human tissues

P. Beaune, T. Asselah, P. Marcellin, 2007, Pharmacogenetics and genomics.

Cortical branched actin determines cell cycle progression

A. Gautreau, S. Vacher, I. Bièche, 2019, Cell Research.

Cell death and neuronal differentiation of glioblastoma stem‐like cells induced by neurogenic transcription factors

H. Duffau, J. Mallet, S. Vacher, 2013, Glia.

Differential Distribution of erbB Receptors in Human Glioblastoma Multiforme: Expression of erbB3 in CD133-Positive Putative Cancer Stem Cells

S. Vacher, I. Bièche, S. Blond, 2010, Journal of neuropathology and experimental neurology.

Prognostic value of tumor mutational burden in patients with oral cavity squamous cell carcinoma treated with upfront surgery

O. Mariani, J. Klijanienko, S. Vacher, 2021, ESMO open.

Prognostic value of a newly identified MALAT1 alternatively spliced transcript in breast cancer

Antonin Morillon, Rosette Lidereau, Didier Meseure, 2016, British Journal of Cancer.

Biomarkers of cetuximab resistance in patients with head and neck squamous cell carcinoma

J. Klijanienko, S. Vacher, I. Bièche, 2020, Cancer biology & medicine.

Profiling of EGFR mRNA and protein expression in 471 breast cancers compared with 10 normal tissues: A candidate biomarker to predict EGFR inhibitor effectiveness

S. Vacher, I. Bièche, R. Lidereau, 2012, International journal of cancer.

Identification of new candidate therapeutic target genes in triple-negative breast cancer.

Rosette Lidereau, Didier Meseure, S. Vacher, 2012, Genes & cancer.

PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups

Rosette Lidereau, S. Vacher, I. Bièche, 2012, Breast Cancer Research.

Arpin downregulation in breast cancer is associated with poor prognosis

F. Lallemand, A. Gautreau, S. Vacher, 2016, British Journal of Cancer.

Expression of ANRIL–Polycomb Complexes–CDKN2A/B/ARF Genes in Breast Tumors: Identification of a Two-Gene (EZH2/CBX7) Signature with Independent Prognostic Value

S. Vacher, A. Nicolas, I. Bièche, 2016, Molecular Cancer Research.

High Prevalence of a Hotspot of Noncoding Somatic Mutations in Intron 6 of GPR126 in Bladder Cancer

Y. Allory, S. Vacher, I. Bièche, 2018, Molecular Cancer Research.

BRCAness, SLFN11, and RB1 loss predict response to topoisomerase I inhibitors in triple-negative breast cancers

Y. Pommier, A. Salomon, S. Vacher, 2020, Science Translational Medicine.

Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer

S. Vacher, I. Bièche, V. Bernard, 2018, Breast Cancer Research.

Vandetanib as a potential new treatment for estrogen receptor‐negative breast cancers

S. Vacher, I. Bièche, V. Diéras, 2016, International journal of cancer.

VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX

F. Lallemand, A. Vincent-Salomon, S. Vacher, 2018, BMC Biology.

Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition.

S. Vacher, I. Bièche, B. Robert, 2022, Journal of cell science.

Flotillin-upregulation acts as an epithelial-mesenchymal transition driver by promoting sphingosine kinase 2-dependent AXL stabilization Running title : Upregulated-flotillins drive EMT via SphK2 and AXL

S. Vacher, I. Bièche, B. Robert, 2020 .

Upregulated-flotillins and sphingosine kinase 2 derail vesicular trafic to stabilize AXL and promote epithelial-mesenchymal transition

S. Vacher, I. Bièche, B. Robert, 2020, bioRxiv.

Epithelial-to-mesenchymal transition: EMT Plasma membrane: PM Receptor Tyrosine Kinases: RTKs Sphingosine kinase 2: SphK2 Sphingosine 1-phosphate: S1P Upregulated Flotillin-Induced Trafficking: UFIT

S. Vacher, I. Bièche, B. Robert, 2020 .

MT1-MMP targeting to endolysosomes is mediated by upregulation of flotillins

S. Vacher, I. Bièche, P. Chavrier, 2018, Journal of Cell Science.

The iron chelator deferasirox synergises with chemotherapy to treat triple‐negative breast cancers

F. Lallemand, S. Vacher, I. Bièche, 2018, The Journal of pathology.

Identification of novel genes that co-cluster with estrogen receptor alpha in breast tumor biopsy specimens, using a large-scale real-time reverse transcription-PCR approach.

S. Vacher, I. Bièche, S. Tozlu, 2006, Endocrine-related cancer.

Inactivation of the Kinase Domain of CDK10 Prevents Tumor Growth in a Preclinical Model of Colorectal Cancer, and Is Accompanied by Downregulation of Bcl-2

A. Weng, S. Vacher, L. weiswald, 2017, Molecular Cancer Therapeutics.

Metastasis-suppressor NME1 controls the invasive switch of breast cancer by regulating MT1-MMP surface clearance

A. Vincent-Salomon, S. Weiss, O. De Wever, 2021, Oncogene.

BMC Cancer BioMed Central Research article NF-kappa B genes have a major role in Inflammatory Breast Cancer

Rosette Lidereau, M. Espié, S. Vacher, 2008 .

Clinical value of R-spondins in triple-negative and metaplastic breast cancers

F. Lallemand, S. Vacher, S. Richon, 2017, British Journal of Cancer.

EHD2 is a Predictive Biomarker of Chemotherapy Efficacy in Triple Negative Breast Carcinoma

A. Vincent-Salomon, S. Vacher, I. Bièche, 2020, Scientific Reports.

CXC chemokines located in the 4q21 region are up-regulated in breast cancer.

S. Vacher, I. Bièche, R. Lidereau, 2007, Endocrine-related cancer.

Unraveling the Role of Huntingtin in Breast Cancer Metastasis.

Anne Vincent-Salomon, A. Vincent-Salomon, S. Vacher, 2015, Journal of the National Cancer Institute.

Assessment of prognostic implication of a panel of oncogenes in bladder cancer and identification of a 3-gene signature associated with recurrence and progression risk in non-muscle-invasive bladder cancer

Y. Allory, S. Vacher, I. Bièche, 2020, Scientific Reports.

PLK1 inhibition exhibits strong anti-tumoral activity in CCND1-driven breast cancer metastases with acquired palbociclib resistance

A. Vincent-Salomon, S. Vacher, A. Nicolas, 2020, Nature Communications.

Medullary Breast Carcinoma, a Triple-Negative Breast Cancer Associated with BCLG Overexpression.

A. Vincent-Salomon, O. Delattre, R. Rouzier, 2018, The American journal of pathology.

Inhibition of PI3K pathway increases immune infiltrate in muscle-invasive bladder cancer

Y. Allory, F. Radvanyi, S. Vacher, 2019, Oncoimmunology.

Identification of 5 novel genes methylated in breast and other epithelial cancers

David Euhus, J. Minna, L. Hesson, 2010, Molecular Cancer.

Interleukin-8 Receptors CXCR1 and CXCR2 Are Not Expressed by Endothelial Colony-forming Cells

S. Vacher, I. Bièche, P. Gaussem, 2020, Stem Cell Reviews and Reports.

Hedgehog pathway activation in human transitional cell carcinoma of the bladder

S. Vacher, I. Bièche, R. Lidereau, 2012, British Journal of Cancer.

Biopathological Significance of PIWI–piRNA Pathway Deregulation in Invasive Breast Carcinomas

S. Vacher, A. Nicolas, I. Bièche, 2020, Cancers.

Coronin 1C promotes triple-negative breast cancer invasiveness through regulation of MT1-MMP traffic and invadopodia function

A. Vincent-Salomon, S. Vacher, I. Bièche, 2018, Oncogene.

Quantification of PKC family genes in sporadic breast cancer by qRT‐PCR: Evidence that PKCι/λ overexpression is an independent prognostic factor

S. Vacher, I. Bièche, R. Lidereau, 2012, International journal of cancer.

Inhibitory signalling to the Arp2/3 complex steers cell migration

Nadine Peyriéras, Laurent Blanchoin, Ksenia Oguievetskaia, 2013, Nature.

Acquired Resistance to Endocrine Treatments Is Associated with Tumor-Specific Molecular Changes in Patient-Derived Luminal Breast Cancer Xenografts

S. Vacher, S. Roman-Roman, I. Bièche, 2014, Clinical Cancer Research.

Combination of PI3K and MEK inhibitors yields durable remission in PDX models of PIK3CA-mutated metaplastic breast cancers

A. Salomon, S. Vacher, I. Bièche, 2020, Journal of Hematology & Oncology.

MDA-MB-231 breast cancer cells overexpressing single VEGF isoforms display distinct colonisation characteristics

S. Vacher, I. Bièche, M. Pocard, 2015, British Journal of Cancer.

MiR-190b, the highest up-regulated miRNA in ERα-positive compared to ERα-negative breast tumors, a new biomarker in breast cancers?

F. Lallemand, S. Vacher, I. Bièche, 2015, BMC Cancer.

Response to mTOR and PI3K inhibitors in enzalutamide-resistant luminal androgen receptor triple-negative breast cancer patient-derived xenografts

A. Salomon, S. Vacher, I. Bièche, 2020, Theranostics.

ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

S. Vacher, I. Bièche, Y. De Launoit, 2018, Breast Cancer Research.

ATM has a major role in the double-strand break repair pathway dysregulation in sporadic breast carcinomas and is an independent prognostic marker at both mRNA and protein levels

S. Vacher, I. Bièche, R. Lidereau, 2015, British Journal of Cancer.

SISH/CISH or qPCR as alternative techniques to FISH for determination of HER2 amplification status on breast tumors core needle biopsies: a multicenter experience based on 840 cases

L. Xerri, A. Salomon, B. Esterni, 2013, BMC Cancer.

Differential gene expression in growth factors, epithelial mesenchymal transition and chemotaxis in the diffuse type compared with the intestinal type of gastric cancer

S. Vacher, I. Bièche, M. Pocard, 2019, Oncology letters.

Identification of a large intra-exonic deletion in BRCA2 exon 18 in a pancreatic ductal adenocarcinoma

S. Vacher, I. Bièche, E. Girard, 2023, Therapeutic advances in medical oncology.

Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer patients

Jean-Marc Guinebretière, Nicolas Servant, Bernard Asselain, 2011, BMC Cancer.

Evolution of synchronous bilateral breast cancers provide insights into interactions between host, tumor and immunity.

S. Vacher, I. Bièche, C. Vallot, 2021, medRxiv.

Targeting mTOR pathway inhibits tumor growth in different molecular subtypes of triple-negative breast cancers

S. Vacher, I. Bièche, F. Reyal, 2016, Oncotarget.

Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration

S. Vacher, I. Bièche, C. Janke, 2017, Journal of Cell Science.

Biopathological Significance of TLR9 Expression in Cancer Cells and Tumor Microenvironment Across Invasive Breast Carcinomas Subtypes

S. Vacher, A. Nicolas, I. Bièche, 2016, Cancer Microenvironment.

Identification of new candidate therapeutic target genes in head and neck squamous cell carcinomas

O. Mariani, J. Klijanienko, S. Vacher, 2016, Oncotarget.

Combination of COX-2 expression and PIK3CA mutation as prognostic and predictive markers for celecoxib treatment in breast cancer

S. Vacher, I. Bièche, V. Bécette, 2016, Oncotarget.

Efficacy of molecularly targeted agents given in the randomised trial SHIVA01 according to the ESMO Scale for Clinical Actionability of molecular Targets.

S. Vacher, I. Bièche, N. Servant, 2019, European journal of cancer.

Differential Expression of Genes Involved in Metabolism and Immune Response in Diffuse and Intestinal Gastric Cancers, a Pilot Ptudy

S. Vacher, I. Bièche, M. Pocard, 2022, Biomedicines.

High AHR expression in breast tumors correlates with expression of genes from several signaling pathways namely inflammation and endogenous tryptophan metabolism

F. Lallemand, S. Vacher, I. Bièche, 2018, PloS one.

P-cadherin-induced decorin secretion is required for collagen fiber alignment and directional collective cell migration

S. Vacher, I. Bièche, E. Bazellières, 2019, Journal of Cell Science.

Exome sequencing reveals aberrant signalling pathways as hallmark of treatment-naive anal squamous cell carcinoma

O. Mariani, S. Vacher, S. Richon, 2017, Oncotarget.

Cdk5 promotes DNA replication stress checkpoint activation through RPA-32 phosphorylation, and impacts on metastasis free survival in breast cancer patients

S. Vacher, I. Bièche, D. Biard, 2015, Cell cycle.

Rosette Lidereau, S. Vacher, I. Bièche, 2011, PloS one.

PKD1 is a potential biomarker and therapeutic target in triple-negative breast cancer

S. Vacher, I. Bièche, J. Ricort, 2018, Oncotarget.

Variations in the mRNA expression of poly(ADP‐ribose) polymerases, poly(ADP‐ribose) glycohydrolase and ADP‐ribosylhydrolase 3 in breast tumors and impact on clinical outcome

S. Vacher, I. Bièche, R. Lidereau, 2013, International journal of cancer.

Gene Expression Profiling Reveals New Aspects of PIK 3 CA Mutation in ERalpha-Positive Breast Cancer : Major Implication of the Wnt Signaling Pathway

S. Vacher, I. Bièche, R. Lidereau, 2010 .

The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor

O. De Wever, S. Vacher, I. Bièche, 2021, BMC biology.

Human papilloma virus (HPV) integration signature in Cervical Cancer: identification of MACROD2 gene as HPV hot spot integration site

S. Rodenhuis, E. Barillot, A. Nicolas, 2020, British Journal of Cancer.

A short-term colorectal cancer sphere culture as a relevant tool for human cancer biology investigation

S. Vacher, S. Richon, L. weiswald, 2013, British Journal of Cancer.

ZRANB2 and SYF2-mediated splicing programs converging on ECT2 are involved in breast cancer cell resistance to doxorubicin

E. Lam, O. Delattre, S. Vacher, 2020, Nucleic acids research.

ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas

A. Vincent-Salomon, R. Rouzier, S. Vacher, 2016, Oncotarget.

mRNA Expression levels of genes involved in antitumor immunity: Identification of a 3-gene signature associated with prognosis of muscle-invasive bladder cancer

S. Vacher, I. Bièche, M. Sibony, 2017, Oncoimmunology.

High tumoral levels of Kiss1 and G-protein-coupled receptor 54 expression are correlated with poor prognosis of estrogen receptor-positive breast tumors.

Didier Marot, Rosette Lidereau, M. Perricaudet, 2007, Endocrine-related cancer.

Evolution of synchronous female bilateral breast cancers and response to treatment

O. Mariani, A. Vincent-Salomon, S. Vacher, 2023, Nature Medicine.

Gain-of-function Prolactin Receptor Variants Are Not Associated With Breast Cancer and Multiple Fibroadenoma Risk.

S. Vacher, I. Bièche, P. Camparo, 2016, The Journal of clinical endocrinology and metabolism.

CAG repeat size in Huntingtin alleles is associated with cancer prognosis

A. Durr, S. Vacher, I. Bièche, 2016, European Journal of Human Genetics.

Cytidine Deaminase Deficiency Reveals New Therapeutic Opportunities against Cancer

W. Reinhold, Y. Pommier, S. Vacher, 2016, Clinical Cancer Research.

Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy

F. Lallemand, S. Vacher, I. Bièche, 2011, Molecular Cancer.

Protein kinase D1 regulates ERα-positive breast cancer cell growth response to 17β-estradiol and contributes to poor prognosis in patients

S. Vacher, I. Bièche, J. Ricort, 2014, Journal of cellular and molecular medicine.

PIK3R1 underexpression is an independent prognostic marker in breast cancer

S. Vacher, I. Bièche, R. Lidereau, 2013, BMC Cancer.

Cortical branched actin determines cell cycle progression

A. Gautreau, S. Vacher, I. Bièche, 2019, Cell Research.

ERRα promotes breast cancer cell dissemination to bone by increasing RANK expression in primary breast tumors

J. Aubin, M. Gnant, S. Vacher, 2018, Oncogene.

Prognostic Impact of Residual HPV ctDNA Detection after Chemoradiotherapy for Anal Squamous Cell Carcinoma

A. Vincent-Salomon, S. Vacher, A. Lièvre, 2018, Clinical Cancer Research.

MED12 mutations in breast phyllodes tumors: evidence of temporal tumoral heterogeneity and identification of associated critical signaling pathways

O. Mariani, S. Vacher, I. Bièche, 2016, Oncotarget.

Array comparative genomic hybridization identifies high level of PI3K/Akt/mTOR pathway alterations in anal cancer recurrences

O. Mariani, S. Vacher, S. Richon, 2018, Cancer medicine.

DNA repair gene expression and risk of locoregional relapse in breast cancer patients.

S. Vacher, I. Bièche, R. Lidereau, 2010, International journal of radiation oncology, biology, physics.

Prognostic value of intratumoral Fusobacterium nucleatum and association with immune-related gene expression in oral squamous cell carcinoma patients

O. Mariani, J. Klijanienko, S. Vacher, 2021, Scientific Reports.

Predictive Gene Signature of Response to the Anti-TweakR mAb PDL192 in Patient-Derived Breast Cancer Xenografts

A. Vincent-Salomon, S. Vacher, A. Nicolas, 2014, PloS one.

PLEKHS1: A new molecular marker predicting risk of progression of non-muscle-invasive bladder cancer

F. Lallemand, Y. Allory, F. Radvanyi, 2019, Oncology letters.

Homologous recombination deficiency derived from whole-genome sequencing predicts platinum response in triple-negative breast cancers

P. Kristel, S. Vacher, I. Bièche, 2023, Nature Communications.

EHD2 is a Predictive Biomarker of Chemotherapy Efficacy in Triple Negative Breast Carcinoma

A. Vincent-Salomon, S. Vacher, I. Bièche, 2020, Scientific Reports.

Activation of IFN/STAT1 signalling predicts response to chemotherapy in oestrogen receptor-negative breast cancer

S. Cairo, S. Vacher, S. Roman-Roman, 2015, British Journal of Cancer.

Oligonucleotide microarray analysis of estrogen receptor alpha-positive postmenopausal breast carcinomas: identification of HRPAP20 and TIMELESS as outstanding candidate markers to predict the response to tamoxifen.

S. Vacher, I. Bièche, V. Lazar, 2007, Journal of molecular endocrinology.

Involvement of the FOXO6 transcriptional factor in breast carcinogenesis

F. Lallemand, S. Vacher, I. Bièche, 2017, OncoTarget.

Intratumoral microbiome is driven by metastatic site and associated with immune histopathological parameters: An ancillary study of the SHIVA clinical trial.

S. Vacher, I. Bièche, N. Servant, 2023, European journal of cancer.

Protein Kinase D1 Regulates Erα-positive Breast Cancer Cell Growth Response To 17βestradiol And Contributes To Poor Prognosis In Patients

S. Vacher, I. Bièche, J. Ricort, 2014 .

Control of MT1-MMP transport by atypical PKC during breast-cancer progression

P. Paul-Gilloteaux, A. Vincent-Salomon, S. Vacher, 2014, Proceedings of the National Academy of Sciences.

The high protein expression of FOXO3, but not that of FOXO1, is associated with markers of good prognosis

F. Lallemand, S. Vacher, I. Bièche, 2020, Scientific Reports.

Phase II study of intrathecal administration of trastuzumab in patients with HER2-positive breast cancer with leptomeningeal metastasis.

S. Vacher, S. Taillibert, O. Trédan, 2022, Neuro-oncology.

Large-scale real-time reverse transcription-PCR approach of angiogenic pathways in human transitional cell carcinoma of the bladder: identification of VEGFA as a major independent prognostic marker.

S. Vacher, I. Bièche, R. Lidereau, 2009, European urology.

Dramatic In Vivo Efficacy of the EZH2-Inhibitor Tazemetostat in PBRM1-Mutated Human Chordoma Xenograft

S. Vacher, A. Nicolas, S. Roman-Roman, 2022, Cancers.

Inactivating Negative Regulators of Cortical Branched Actin Enhances Persistence of Single Cell Migration

A. Gautreau, S. Vacher, I. Bièche, 2023, bioRxiv.

Distinct expression profiles and functions of Kindlins in breast cancer

A. Vincent-Salomon, S. Vacher, I. Bièche, 2018, Journal of Experimental & Clinical Cancer Research.

Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma

M. Delorenzi, S. Vacher, W. Cacheux, 2019, Scientific Reports.

Mechanistic Signatures of Human Papillomavirus Insertions in Anal Squamous Cell Carcinomas

A. Nicolas, O. Mariani, R. Rouzier, 2019, Cancers.

Vasculature analysis of patient derived tumor xenografts using species-specific PCR assays: evidence of tumor endothelial cells and atypical VEGFA-VEGFR1/2 signalings

S. Vacher, S. Richon, S. Roman-Roman, 2014, BMC Cancer.

WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer

F. Lallemand, S. Vacher, I. Bièche, 2023, Cancer Gene Therapy.

VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX

F. Lallemand, A. Vincent-Salomon, S. Vacher, 2018, BMC Biology.

Interaction between IGF2‐PI3K axis and cancer‐associated‐fibroblasts promotes anal squamous carcinogenesis

S. Vacher, S. Richon, A. Lièvre, 2019, International journal of cancer.

MSH3: a confirmed predisposing gene for adenomatous polyposis

Y. Allory, S. Vacher, I. Bièche, 2023, Journal of Medical Genetics.

Limited Sensitivity of Circulating Tumor DNA Detection by Droplet Digital PCR in Non-Metastatic Operable Gastric Cancer Patients

S. Vacher, I. Bièche, F. Bidard, 2019, Cancers.

ERBB3-Activating Mutations in Small Bowel Adenocarcinomas.

S. Vacher, I. Bièche, P. Laurent-Puig, 2018, JCO precision oncology.

Nivolumab plus chemoradiotherapy in locally-advanced cervical cancer: the NICOL phase 1 trial

A. Vincent-Salomon, S. Vacher, I. Bièche, 2023, Nature communications.

Oxidative phosphorylation is a metabolic vulnerability of endocrine therapy and palbociclib resistant metastatic breast cancers

A. Vincent-Salomon, S. Vacher, I. Bièche, 2023, Nature communications.

BMC Cancer BioMed Central Research article NF-kappa B genes have a major role in Inflammatory Breast Cancer

M. Espié, S. Vacher, I. Bièche, 2008 .

Prognostic impact of residual HPV ctDNA detection after chemoradiotherapy for anal canal carcinoma.

S. Vacher, A. Lièvre, W. Cacheux, 2018 .

First report of medulloblastoma in a patient with MUTYH‐associated polyposis

S. Vacher, I. Bièche, D. Stoppa-Lyonnet, 2023, Neuropathology and applied neurobiology.

Rare overexpression of anaplastic lymphoma kinase gene in inflammatory and non-inflammatory breast cancer.

S. Vacher, I. Bièche, F. Lerebours, 2013, European journal of cancer.

Epithelial-to-Mesenchymal Transition

S. Vacher, I. Bièche, B. Robert, 2020, Definitions.

Prospective validation in epithelial tumors of a gene expression predictor of liver metastasis derived from uveal melanoma

M. Delorenzi, S. Vacher, W. Cacheux, 2019, Scientific Reports.

901 Bacillus Calmette-Guerin can subvert patients antitumor immune response by downregulating HLA-I expression on cancer cells

T. Tan, J. Thiery, L. Zitvogel, 2021, Journal for ImmunoTherapy of Cancer.

Limited Sensitivity of Circulating Tumor DNA Detection by Droplet Digital PCR in Non-Metastatic Operable Gastric Cancer Patients

S. Vacher, I. Bièche, F. Bidard, 2019, Cancers.

Altered Expression of Three EGFR Posttranslational Regulators MDGI, MIG6, and EIG121 in Invasive Breast Carcinomas

S. Vacher, A. Nicolas, I. Bièche, 2020, Analytical cellular pathology.

Molecular characterisation of tumours of the lacrimal apparatus.

A. Vincent-Salomon, S. Vacher, E. Girard, 2023, Histopathology.

Germline HPF1 retrogene insertion in RB1 gene involved in cancer predisposition

F. Lallemand, F. Radvanyi, S. Vacher, 2023, Journal of medical genetics.

In utero and lactational exposure to vinclozolin and genistein induces genomic changes in the rat mammary gland.

S. Vacher, I. Bièche, M. Pocard, 2013, The Journal of endocrinology.

Medullary Breast Carcinoma, a Triple-Negative Breast Cancer Associated with BCLG Overexpression.

A. Vincent-Salomon, O. Delattre, R. Rouzier, 2018, The American journal of pathology.

Tubulin glycylases are required for primary cilia, control of cell proliferation and tumor development in colon

S. Vacher, W. Cacheux, I. Bièche, 2014, EMBO Journal.

A large collection of integrated genomically characterized patient‐derived xenografts highlighting the heterogeneity of triple‐negative breast cancer

A. Vincent-Salomon, S. Vacher, I. Bièche, 2019, International journal of cancer.

Randomized phase II study of preoperative afatinib in untreated head and neck cancers: predictive and pharmacodynamic biomarkers of activity

S. Vacher, E. Girard, M. Kamal, 2023, Scientific reports.

Inhibitory signalling to the Arp2/3 complex steers cell migration

J. Cherfils, E. Derivery, A. Gautreau, 2013, Nature.

Capecitabine Efficacy Is Correlated with TYMP and RB1 Expression in PDX Established from Triple-Negative Breast Cancers

M. Piccart, A. Vincent-Salomon, S. Vacher, 2018, Clinical Cancer Research.

Mosaic BRCA1 promoter methylation contribution in hereditary breast/ovarian cancer pedigrees

S. Vacher, I. Bièche, V. Bécette, 2023, Journal of Medical Genetics.

MET functions in tumour progression and therapy resistance are repressed by intronic polyadenylation

Céline M. Labbé, P. Gestraud, S. Vacher, 2023, bioRxiv.

Evaluating patient-derived colorectal cancer xenografts as preclinical models by comparison with patient clinical data.

D. Bergstrom, Weidong Zhang, C. Dib, 2015, Cancer research.

Analysis of genomic and non-genomic signaling of estrogen receptor in PDX models of breast cancer treated with a combination of the PI3K inhibitor alpelisib (BYL719) and fulvestrant

S. Vacher, I. Treilleux, E. Marangoni, 2021, Breast Cancer Research.