Huan‐Xiang Zhou

发表

Macromolecular crowding and confinement: biochemical, biophysical, and potential physiological consequences.

Huan‐Xiang Zhou, G. Rivas, A. Minton, 2008, Annual review of biophysics.

Prediction of solvent accessibility and sites of deleterious mutations from protein sequence

Huan‐Xiang Zhou, Huiling Chen, 2005, Nucleic acids research.

Protein Allostery and Conformational Dynamics.

Huan‐Xiang Zhou, Jingjing Guo, 2016, Chemical reviews.

Two pathways mediate interdomain allosteric regulation in pin1.

Jingjing Guo, Huan-Xiang Zhou, Xiaodong Pang, 2015, Structure.

Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation.

Huan‐Xiang Zhou, Xiaodong Pang, 2018, Chemical reviews.

Electrostatic contributions to T4 lysozyme stability: solvent-exposed charges versus semi-buried salt bridges.

Huan-Xiang Zhou, Feng Dong, Huan‐Xiang Zhou, 2002, Biophysical journal.

Loops, linkages, rings, catenanes, cages, and crowders: entropy-based strategies for stabilizing proteins.

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2004, Accounts of chemical research.

Electrostatic effects on the folding stability of FKBP12.

Huan‐Xiang Zhou, Harianto Tjong, J. Batra, 2006, Protein engineering, design & selection : PEDS.

A Gaussian-chain model for treating residual charge–charge interactions in the unfolded state of proteins

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Challenges in structural approaches to cell modeling.

Jie Liang, S. Vajda, I. Vakser, 2016, Journal of molecular biology.

Influences of membrane mimetic environments on membrane protein structures.

Huan‐Xiang Zhou, T. Cross, 2013, Annual review of biophysics.

Recent progress in structure-based anti-influenza drug design.

Huan‐Xiang Zhou, T. Cross, Juan Du, 2012, Drug discovery today.

Influence of solubilizing environments on membrane protein structures.

Huan-Xiang Zhou, Mukesh Sharma, Timothy A Cross, 2011, Trends in biochemical sciences.

Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer

Huan‐Xiang Zhou, T. Cross, Mukesh Sharma, 2010, Science.

A rate process with an entropy barrier

Huan-Xiang Zhou, Robert Zwanzig, R. Zwanzig, 1991 .

Rate theories for biologists

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2010, Quarterly Reviews of Biophysics.

How do biomolecular systems speed up and regulate rates?

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2005, Physical biology.

Theory of the diffusion-influenced substrate binding rate to a buried and gated active site

Huan-Xiang Zhou, Huan‐Xiang Zhou, 1998 .

Comparison of three Brownian-dynamics algorithms for calculating rate constants of diffusion-influenced reactions

Huan-Xiang Zhou, Huan‐Xiang Zhou, 1998 .

EFFECT OF INTERACTION POTENTIALS IN DIFFUSION-INFLUENCED REACTIONS WITH SMALL REACTIVE REGIONS

Huan‐Xiang Zhou, 1996 .

A solvable model for the diffusion and reaction of neurotransmitters in a synaptic junction

Huan-Xiang Zhou, Huan‐Xiang Zhou, J. Barreda, 2011, BMC biophysics.

Shape Recovery of Deformed Biomolecular Droplets: Dependence on Condensate Viscoelasticity

Huan‐Xiang Zhou, 2021, bioRxiv.

Shear relaxation governs fusion dynamics of biomolecular condensates

Huan‐Xiang Zhou, Archishman Ghosh, Divya Kota, 2021, Nature Communications.

Shear Relaxation Governs Dynamic Processes of Biomolecular Condensates

Huan‐Xiang Zhou, Archishman Ghosh, Divya Kota, 2021, bioRxiv.

Viscoelasticity of biomolecular condensates conforms to the Jeffreys model

Huan‐Xiang Zhou, 2020, bioRxiv.

Determination of Condensate Material Properties from Droplet Deformation.

Huan‐Xiang Zhou, 2020, The journal of physical chemistry. B.

Determinants for Fusion Speed of Biomolecular Droplets.

Huan‐Xiang Zhou, Archishman Ghosh, 2020, Angewandte Chemie.

Comparison between molecular dynamics simulations and the Smoluchowski theory of reactions in a hard‐sphere liquid

Huan‐Xiang Zhou, A. Szabó, 1991 .

PI2PE: a suite of web servers for predictions ranging from protein structure to binding kinetics

Huan‐Xiang Zhou, Sanbo Qin, 2013, Biophysical Reviews.

Selection of near‐native poses in CAPRI rounds 13‐19

Huan‐Xiang Zhou, Sanbo Qin, 2010, Proteins.

Electrostatic rate enhancement and transient complex of protein–protein association

Huan‐Xiang Zhou, R. Alsallaq, 2008, Proteins.

Automated prediction of protein association rate constants.

Huan‐Xiang Zhou, Sanbo Qin, Xiaodong Pang, 2011, Structure.

Community‐wide evaluation of methods for predicting the effect of mutations on protein–protein interactions

Julie C. Mitchell, Jeffrey J. Gray, Z. Weng, 2013, Proteins.

Calculation of protein-ligand binding affinities.

M. Gilson, Huan‐Xiang Zhou, 2007, Annual review of biophysics and biomolecular structure.

Temperature-induced collapse of a disordered peptide observed by three sampling methods in molecular dynamics simulations.

Huan‐Xiang Zhou, Alan Hicks, 2018, The Journal of chemical physics.

Atomistic modeling of macromolecular crowding predicts modest increases in protein folding and binding stability.

Huan‐Xiang Zhou, Sanbo Qin, 2009, Biophysical journal.

Generalized fundamental measure theory for atomistic modeling of macromolecular crowding.

Huan‐Xiang Zhou, Sanbo Qin, 2010, Physical review. E, Statistical, nonlinear, and soft matter physics.

Effects of Macromolecular Crowding on the Conformational Ensembles of Disordered Proteins.

Huan‐Xiang Zhou, Sanbo Qin, 2013, The journal of physical chemistry letters.

The dock‐and‐coalesce mechanism for the association of a WASP disordered region with the Cdc42 GTPase

Huan‐Xiang Zhou, L. Ou, Xiaodong Pang, 2017, The FEBS journal.

Mechanism and rate constants of the Cdc42 GTPase binding with intrinsically disordered effectors

Huan‐Xiang Zhou, Xiaodong Pang, 2016, Proteins.

Rate constants and mechanisms of intrinsically disordered proteins binding to structured targets.

Huan‐Xiang Zhou, Xiaodong Pang, Cai Lu, 2012, Physical chemistry chemical physics : PCCP.

Modeling protein association mechanisms and kinetics.

P. Bates, Huan‐Xiang Zhou, 2013, Current opinion in structural biology.

Rate Constants and Mechanisms of Protein-Ligand Binding.

Huan‐Xiang Zhou, Xiaodong Pang, 2017, Annual review of biophysics.

Improving the understanding of human genetic diseases through predictions of protein structures and protein-protein interaction sites.

Huan‐Xiang Zhou, 2004, Current medicinal chemistry.

Inter- and intrasubunit interactions between transmembrane helices in the open state of P2X receptor channels

S. Silberberg, Huan‐Xiang Zhou, K. Swartz, 2013, Proceedings of the National Academy of Sciences.

Dynamic Short Hydrogen Bonds in Histidine Tetrad of Full-Length M2 Proton Channel Reveal Tetrameric Structural Heterogeneity and Functional Mechanism.

Huan‐Xiang Zhou, R. Fu, T. Cross, 2015, Structure.

Differential Binding of Rimantadine Enantiomers to Influenza A M2 Proton Channel.

Huan‐Xiang Zhou, I. Hung, T. Cross, 2016, Journal of the American Chemical Society.

From induced fit to conformational selection: a continuum of binding mechanism controlled by the timescale of conformational transitions.

Huan‐Xiang Zhou, 2010, Biophysical journal.

Both protein dynamics and ligand concentration can shift the binding mechanism between conformational selection and induced fit

Huan‐Xiang Zhou, Nicholas Greives, 2014, Proceedings of the National Academy of Sciences.

Influence of crowded cellular environments on protein folding, binding, and oligomerization: Biological consequences and potentials of atomistic modeling

Huan‐Xiang Zhou, 2013, FEBS letters.

Protein folding, binding, and droplet formation in cell-like conditions.

Huan‐Xiang Zhou, Sanbo Qin, 2017, Current opinion in structural biology.

Theoretical frameworks for multiscale modeling and simulation.

Huan‐Xiang Zhou, 2014, Current opinion in structural biology.

Theory of free energy and entropy in noncovalent binding.

Michael K. Gilson, Huan-Xiang Zhou, M. Gilson, 2009, Chemical reviews.

Electrostatic contribution to the binding stability of protein–protein complexes

Huan-Xiang Zhou, Feng Dong, Huan‐Xiang Zhou, 2006, Proteins.

Semiclosed Conformations of the Ligand-Binding Domains of NMDA Receptors during Stationary Gating.

Huan-Xiang Zhou, Huan‐Xiang Zhou, Jian Dai, 2016, Biophysical journal.

GBr(6): a parameterization-free, accurate, analytical generalized born method.

Harianto Tjong, Huan-Xiang Zhou, Huan‐Xiang Zhou, 2007, The journal of physical chemistry. B.

Blind prediction of interfacial water positions in CAPRI

Kengo Kinoshita, Haruki Nakamura, Xiaoqin Zou, 2014, Proteins.

Macromolecular electrostatic energy within the nonlinear Poisson–Boltzmann equation

Huan-Xiang Zhou, Huan‐Xiang Zhou, 1994 .

Effects of pH, salt, and macromolecular crowding on the stability of FK506-binding protein: an integrated experimental and theoretical study.

Huan-Xiang Zhou, T. Logan, Huan‐Xiang Zhou, 2005, Journal of molecular biology.

Polymer models of protein stability, folding, and interactions.

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2004, Biochemistry.

On the Dielectric Boundary in Poisson-Boltzmann Calculations.

Harianto Tjong, Huan-Xiang Zhou, Huan‐Xiang Zhou, 2008, Journal of chemical theory and computation.

GBr6NL: a generalized Born method for accurately reproducing solvation energy of the nonlinear Poisson-Boltzmann equation.

Harianto Tjong, Huan-Xiang Zhou, Huan‐Xiang Zhou, 2007, The Journal of chemical physics.

Structural models of protein-DNA complexes based on interface prediction and docking.

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2011, Current protein & peptide science.

MODELING THE PHYSICAL CHEMISTRY OF BINDING : FORCES AND FLEXIBILITY

M. Gilson, Huan‐Xiang Zhou, 2007 .

A method to determine dielectric constants in nonhomogeneous systems: application to biological membranes.

Huan-Xiang Zhou, Hugh Nymeyer, H. Nymeyer, 2008, Biophysical journal.

Fast Method for Computing Chemical Potentials and Liquid-Liquid Phase Equilibria of Macromolecular Solutions.

Huan‐Xiang Zhou, Sanbo Qin, 2016, The journal of physical chemistry. B.

Competitive Interactions of Ligands and Macromolecular Crowders with Maltose Binding Protein

Huan‐Xiang Zhou, Andrew C Miklos, Matthew Sumpter, 2013, PloS one.

Modeling Protein–Protein and Protein–Nucleic Acid Interactions: Structure, Thermodynamics, and Kinetics

Huan‐Xiang Zhou, Sanbo Qin, Harianto Tjong, 2008 .

Atomistic Mechanism for the Activation and Desensitization of an AMPA-Subtype Glutamate Receptor

Huan-Xiang Zhou, Huan‐Xiang Zhou, H. Dong, 2011, Nature communications.

Advancing NMDA Receptor Physiology by Integrating Multiple Approaches

L. Wollmuth, Huan‐Xiang Zhou, 2017, Trends in Neurosciences.

The Transmembrane Domain Mediates Tetramerization of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors*

L. Wollmuth, Huan‐Xiang Zhou, Jian Dai, 2016, The Journal of Biological Chemistry.

Designed Mutations Alter the Binding Pathways of an Intrinsically Disordered Protein

Huan‐Xiang Zhou, Di Wu, 2019, Scientific Reports.

SAXS/SANS probe of intermolecular interactions in concentrated protein solutions.

Huan‐Xiang Zhou, O. Bilsel, 2014, Biophysical journal.

Shape Recovery of Deformed Biomolecular Droplets: Dependence on Condensate Viscoelasticity

Huan‐Xiang Zhou, 2021, bioRxiv.

Sequence-Dependent Correlated Segments in the Intrinsically Disordered Region of ChiZ

Huan‐Xiang Zhou, T. Cross, Alan Hicks, 2020, bioRxiv.

Sequence-Dependent Correlated Segments in the Intrinsically Disordered Region of ChiZ

Huan‐Xiang Zhou, T. Cross, Alan Hicks, 2020, Biomolecules.

Theory and simulation of stochastically-gated diffusion-influenced reactions

Huan‐Xiang Zhou, A. Szabó, 1996 .

Q&A: What is biophysics?

Huan‐Xiang Zhou, 2011, BMC Biology.

Energy between Two Proteins

Huan‐Xiang Zhou, 2005 .

A Tug of War Between Condensate Phases in a Minimal Macromolecular System.

Huan‐Xiang Zhou, Archishman Ghosh, Xiaojia Zhang, 2020, Journal of the American Chemical Society.

A Tug of War Between Condensate Phases in a Minimal Macromolecular System

Huan‐Xiang Zhou, Archishman Ghosh, Xiaojia Zhang, 2020, bioRxiv.

Diffusion-Influenced Transport of Ions across a Transmembrane Channel with an Internal Binding Site.

Huan‐Xiang Zhou, 2010, The journal of physical chemistry letters.

A theory for the proton transport of the influenza virus M2 protein: extensive test against conductance data.

Huan‐Xiang Zhou, 2011, Biophysical journal.

A 240-fold electrostatic rate-enhancement for acetylcholinesterase-substrate binding can be predicted by the potential within the active site

J. Briggs, J. Mccammon, Huan‐Xiang Zhou, 1996 .

Three archetypical classes of macromolecular regulators of protein liquid–liquid phase separation

Huan‐Xiang Zhou, Archishman Ghosh, Konstantinos P. Mazarakos, 2019, Proceedings of the National Academy of Sciences.

Prediction of protein-protein association rates from a transition-state theory.

Huan‐Xiang Zhou, R. Alsallaq, 2007, Structure.

Transfer Free Energies of Test Proteins Into Crowded Protein Solutions Have Simple Dependence on Crowder Concentration

Huan‐Xiang Zhou, Sanbo Qin, V. Nguemaha, 2019, Front. Mol. Biosci..

Energy landscape and transition state of protein-protein association.

Huan‐Xiang Zhou, R. Alsallaq, 2006, Biophysical journal.

Rugged Metropolis sampling with simultaneous updating of two dynamical variables.

Huan‐Xiang Zhou, Bernd A. Berg, 2005, Physical review. E, Statistical, nonlinear, and soft matter physics.

Effects of Mutations and Complex Formation on the Reduction Potentials of Cytochrome c and Cytochrome c Peroxidase

Huan‐Xiang Zhou, 1994 .

Influenza A M2 Channel Clustering at High Protein/Lipid Ratios: Viral Budding Implications.

Huan‐Xiang Zhou, I. Hung, Xiaodong Pang, 2019, Biophysical journal.

Mean field theory of transient fluorescence quenching in the frequency domain

Huan‐Xiang Zhou, A. Szabó, 1990 .

How often does the myristoylated N‐terminal latch of c‐Abl come off?

Huan‐Xiang Zhou, 2003, FEBS letters.

Mechanistic Insight into the H2O/D2O Isotope Effect in the Proton Transport of the Influenza Virus M2 Protein

Huan‐Xiang Zhou, 2011, The Journal of Membrane Biology.

Mechanistic Insight into the H 2 O / D 2 O Isotope Effect in the Proton Transport of the Influenza Virus M 2 Protein

Huan‐Xiang Zhou, 2011 .

Macromolecular Regulators Have Matching Effects on the Phase Equilibrium and Interfacial Tension of Biomolecular Condensates

Huan‐Xiang Zhou, Konstantinos P. Mazarakos, 2021, bioRxiv.

Shape recovery of deformed biomolecular droplets: Dependence on condensate viscoelasticity.

Huan‐Xiang Zhou, 2021, The Journal of chemical physics.

Fusion Speed of Biomolecular Condensates

Huan‐Xiang Zhou, Archishman Ghosh, 2020, bioRxiv.

Dielectric continuum model for calculating reorganization free energies of electron transfer in proteins

Huan‐Xiang Zhou, 1996 .

Position-dependent stabilizing effects in .alpha.-helices: N-terminal capping in synthetic model peptides

P. Lyu, Huan‐Xiang Zhou, D. Wemmer, 1992 .

Diffusion-influenced ligand binding to buried sites in macromolecules and transmembrane channels.

A. Berezhkovskii, Huan‐Xiang Zhou, A. Szabó, 2011, The Journal of chemical physics.

Facilitated phase transformation of PVDF in its composite with an ionic liquid

Huan‐Xiang Zhou, Haibo Yang, Haijun Wang, 2021 .

Glycines: role in α-helical membrane protein structures and a potential indicator of native conformation.

Huan‐Xiang Zhou, T. Cross, Mukesh Sharma, 2012, Biochemistry.

Gating mechanism of a P2X4 receptor developed from normal mode analysis and molecular dynamics simulations

Huan‐Xiang Zhou, Juan Du, H. Dong, 2012, Proceedings of the National Academy of Sciences.

Solid-state NMR evidence for β-hairpin structure within MAX8 designer peptide nanofibers.

Maxwell I. Zimmerman, Huan‐Xiang Zhou, Xiaodong Pang, 2013, Biophysical journal.

Polymer crowders and protein crowders act similarly on protein folding stability

Huan‐Xiang Zhou, 2013, FEBS letters.

The gates of ion channels and enzymes.

J Andrew McCammon, Huan-Xiang Zhou, J. Mccammon, 2010, Trends in biochemical sciences.

Prediction of protein solubility from calculation of transfer free energy.

Harianto Tjong, Huan-Xiang Zhou, Huan‐Xiang Zhou, 2008, Biophysical journal.

Functional stability of water wire–carbonyl interactions in an ion channel

Huan‐Xiang Zhou, I. Hung, T. Cross, 2020, Proceedings of the National Academy of Sciences.

Binding free energy decomposition and multiple unbinding paths of buried ligands in a PreQ1 riboswitch

Huan‐Xiang Zhou, Guodong Hu, 2021, bioRxiv.

Molecular structure of RADA16-I designer self-assembling peptide nanofibers.

Huan-Xiang Zhou, Xiaodong Pang, Maxwell I. Zimmerman, 2013, ACS nano.

Interactions of macromolecules with salt ions: An electrostatic theory for the Hofmeister effect

Huan‐Xiang Zhou, 2005, Proteins.

Effect of backbone cyclization on protein folding stability: chain entropies of both the unfolded and the folded states are restricted.

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2003, Journal of molecular biology.

Rational design of a conformation‐switchable Ca2+‐ and Tb3+‐binding protein without the use of multiple coupled metal‐binding sites

Wei Yang, Harianto Tjong, Jenny J. Yang, 2008, The FEBS journal.

PI2PE: protein interface/interior prediction engine

Harianto Tjong, Huan-Xiang Zhou, Sanbo Qin, 2007, Nucleic Acids Res..

Modeling the membrane environment has implications for membrane protein structure and function: Influenza A M2 protein

Huan‐Xiang Zhou, T. Cross, 2013, Protein science : a publication of the Protein Society.

Why Do Disordered and Structured Proteins Behave Differently in Phase Separation?

Huan‐Xiang Zhou, Sanbo Qin, V. Nguemaha, 2018, Trends in biochemical sciences.

Histidines, heart of the hydrogen ion channel from influenza A virus: toward an understanding of conductance and proton selectivity.

Huan‐Xiang Zhou, K. Nishimura, R. Fu, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Dissection of the high rate constant for the binding of a ribotoxin to the ribosome

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2009, Proceedings of the National Academy of Sciences.

Predicted structures of two proteins involved in human diseases

Huan‐Xiang Zhou, Guoli Wang, 2007, Cell Biochemistry and Biophysics.

A conserved glycine harboring disease-associated mutations permits NMDA receptor slow deactivation and high Ca2+ permeability

L. Wollmuth, Huan‐Xiang Zhou, Xiaoling Leng, 2018, Nature Communications.

Extreme Fuzzy Association of an Intrinsically Disordered Protein with Acidic Membranes

Huan‐Xiang Zhou, T. Cross, Alan Hicks, 2020, bioRxiv.

Divergent roles of a peripheral transmembrane segment in AMPA and NMDA receptors

L. Wollmuth, Huan‐Xiang Zhou, M. Regan, 2017, The Journal of general physiology.

Mechanism-Based Mathematical Model for Gating of Ionotropic Glutamate Receptors.

L. Wollmuth, Huan‐Xiang Zhou, Jian Dai, 2015, The journal of physical chemistry. B.

Mechanical coupling maintains the fidelity of NMDA receptor-mediated currents

L. Wollmuth, Huan‐Xiang Zhou, Jian Dai, 2014, Nature Neuroscience.

Electrostatic contributions to the stability of a thermophilic cold shock protein.

Feng Dong, Huan‐Xiang Zhou, 2003, Biophysical journal.

Toward the physical basis of thermophilic proteins: linking of enriched polar interactions and reduced heat capacity of unfolding.

Huan‐Xiang Zhou, 2002, Biophysical journal.

Spontaneous conformational change and toxin binding in α7 acetylcholine receptor: Insight into channel activation and inhibition

Harianto Tjong, Huan-Xiang Zhou, Huan‐Xiang Zhou, 2008, Proceedings of the National Academy of Sciences.

Out-of-register parallel β-sheets and antiparallel β-sheets coexist in 150 kDa oligomers formed by Aβ(1-42)

Huan‐Xiang Zhou, Yuan Gao, T. Rosenberry, 2020, bioRxiv.

Prediction of protein structures and protein-protein interactions: a bioinformatics approach

Huan-Xiang Zhou, Huiling Chen, Frank A. Ferrone, 2005 .

Prediction of homoprotein and heteroprotein complexes by protein docking and template‐based modeling: A CASP‐CAPRI experiment

Daisuke Kihara, Keehyoung Joo, Daisuke Kuroda, 2016, Proteins.

Prediction of interface residues in protein–protein complexes by a consensus neural network method: Test against NMR data

Huan-Xiang Zhou, Huiling Chen, Huan‐Xiang Zhou, 2005, Proteins.

Prediction of protein interaction sites from sequence profile and residue neighbor list

Huan‐Xiang Zhou, H. Zhou, Y. Shan, 2001, Proteins.

Full Reconstruction of a Vectorial Protein Folding Pathway by Atomic Force Microscopy and Molecular Dynamics Simulations*

Huan-Xiang Zhou, Vann Bennett, Weitao Yang, 2010, The Journal of Biological Chemistry.

Protein folding and binding in confined spaces and in crowded solutions

Huan‐Xiang Zhou, 2004, Journal of molecular recognition : JMR.

A model for the mediation of processivity of DNA-targeting proteins by nonspecific binding: dependence on DNA length and presence of obstacles.

Huan‐Xiang Zhou, 2005, Biophysical journal.

meta-PPISP: a meta web server for protein-protein interaction site prediction

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2007, Bioinform..

Using the concept of transient complex for affinity predictions in CAPRI rounds 20–27 and beyond

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2013, Proteins.

Community-wide assessment of protein-interface modeling suggests improvements to design methodology.

Kengo Kinoshita, Haruki Nakamura, Genki Terashi, 2011, Journal of molecular biology.

Intrinsic disorder: signaling via highly specific but short-lived association.

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2012, Trends in biochemical sciences.

Rapid search for specific sites on DNA through conformational switch of nonspecifically bound proteins

Huan‐Xiang Zhou, 2011, Proceedings of the National Academy of Sciences.

Conformational heterogeneity of the M2 proton channel and a structural model for channel activation

Huan-Xiang Zhou, Timothy A Cross, Huan‐Xiang Zhou, 2009, Proceedings of the National Academy of Sciences.

A secondary gate as a mechanism for inhibition of the M2 proton channel by amantadine.

Huan‐Xiang Zhou, T. Cross, M. Yi, 2008, The journal of physical chemistry. B.

Blocking Effect of an Immuno-Suppressive Agent, Cynarin, on CD28 of T-Cell Receptor

Huan‐Xiang Zhou, Kai-Chun Chang, M. Yi, 2009, Pharmaceutical Research.

Protein folding in confined and crowded environments.

Huan‐Xiang Zhou, 2008, Archives of biochemistry and biophysics.

Helix formation inside a nanotube: possible influence of backbone-water hydrogen bonding by the confining surface through modulation of water activity.

Huan‐Xiang Zhou, 2007, The Journal of chemical physics.

Removing Thermostat Distortions of Protein Dynamics in Constant-Temperature Molecular Dynamics Simulations.

Huan‐Xiang Zhou, Alan Hicks, Matthew MacAinsh, 2021, Journal of chemical theory and computation.

Removing Thermostat Distortions of Protein Dynamics in Constant-Temperature Molecular Dynamics Simulations

Huan‐Xiang Zhou, Alan Hicks, Matthew MacAinsh, 2021, bioRxiv.

Dynamically Driven Protein Allostery Exhibits Disparate Responses for Fast and Slow Motions.

Huan‐Xiang Zhou, Jingjing Guo, 2015, Biophysical journal.

Quantitative computer simulations of biomolecules: A snapshot

Wei Yang, Rafael Brüschweiler, Huan-Xiang Zhou, 2008, J. Comput. Chem..

Backbone dynamics in an intramolecular prolylpeptide-SH3 complex from the diphtheria toxin repressor, DtxR.

T. Logan, Huan‐Xiang Zhou, M. Yi, 2007, Journal of molecular biology.

Fatty Acids Compete with Aβ in Binding to Serum Albumin by Quenching Its Conformational Flexibility.

Huan‐Xiang Zhou, Cong Guo, 2019, Biophysical journal.

Designed Mutations Alter the Binding Pathways of an Intrinsically Disordered Protein

Huan‐Xiang Zhou, Di Wu, 2019, Scientific Reports.

Enhancement of association rates by nonspecific binding to DNA and cell membranes.

Huan-Xiang Zhou, Huan‐Xiang Zhou, A. Szabó, 2004, Physical review letters.

Design Rules for Selective Binding of Nuclear Localization Signals to Minor Site of Importin α

Huan‐Xiang Zhou, Xiaodong Pang, 2014, PloS one.

Author ' s personal copy The gates of ion channels and enzymes

J. Mccammon, Huan‐Xiang Zhou, J. McCammon, 2010 .

Effect of catenation on protein folding stability.

Huan‐Xiang Zhou, 2003, Journal of the American Chemical Society.

General rules for the arrangements and gating motions of pore-lining helices in homomeric ion channels

Huan‐Xiang Zhou, Jian Dai, 2014, Nature Communications.

Dimensions of denatured protein chains from hydrodynamic data

Huan‐Xiang Zhou, 2002 .

Residual electrostatic effects in the unfolded state of the N-terminal domain of L9 can be attributed to nonspecific nonlocal charge-charge interactions.

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2002, Biochemistry.

Loops in Proteins Can Be Modeled as Worm-Like Chains

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2001 .

New Concepts Stabilization of Proteins in Confined Spaces †

K. Dill, Huan‐Xiang Zhou, 2022 .

Effects of Macromolecular Crowding on Protein Conformational Changes

Huan-Xiang Zhou, Hao Dong, Sanbo Qin, 2010, PLoS Comput. Biol..

ReSMAP: Web Server for Predicting Residue-Specific Membrane-Association Propensities of Intrinsically Disordered Proteins

Huan‐Xiang Zhou, Sanbo Qin, Souvik Dey, 2022, Membranes.

Role of diffusion in the kinetics of reversible enzyme-catalyzed reactions.

Huan‐Xiang Zhou, A. Szabó, 2012, Bulletin of the Korean Chemical Society.

Interaction-site prediction for protein complexes: a critical assessment

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2007, Bioinform..

Fundamental Aspects of Protein—Protein Association Kinetics

Gideon Schreiber, Huan-Xiang Zhou, Gilad Haran, 2009 .

Hydrogen bonds between short polar side chains and peptide backbone: Prevalence in proteins and effects on helix‐forming propensities

H. Qian, Huan‐Xiang Zhou, H. Zhou, 1999, Proteins.

The effects of macromolecular crowding on the mechanical stability of protein molecules

Huan‐Xiang Zhou, Jian‐Min Yuan, Haibo Peng, 2008, Protein science : a publication of the Protein Society.

A Common Model for Cytokine Receptor Activation: Combined Scissor-Like Rotation and Self-Rotation of Receptor Dimer Induced by Class I Cytokine

Huan-Xiang Zhou, Xiaodong Pang, Huan‐Xiang Zhou, 2012, PLoS Comput. Biol..

Rationalizing 5000-fold differences in receptor-binding rate constants of four cytokines.

Huan-Xiang Zhou, Sanbo Qin, Xiaodong Pang, 2011, Biophysical journal.

Protein association with circular DNA: rate enhancement by nonspecific binding.

Huan‐Xiang Zhou, R. Alsallaq, 2008, The Journal of chemical physics.

A Brownian dynamics algorithm for calculating the hydrodynamic friction and the electrostatic capacitance of an arbitrarily shaped object

Huan-Xiang Zhou, Jack F. Douglas, Joseph B. Hubbard, 1994 .

Continuum-Model Studies of Redox Reactions, Complex Formation, and Electron Transfer: The Paradigm of Cytochrome c and Cytochrome c Peroxidase

Huan‐Xiang Zhou, 1995 .

Allosteric activation of SENP1 by SUMO1 β-grasp domain involves a dock-and-coalesce mechanism

Huan‐Xiang Zhou, Jingjing Guo, 2016, eLife.

Artificial intelligence guided conformational mining of intrinsically disordered proteins

Huan‐Xiang Zhou, Souvik Dey, Aayush Gupta, 2021, Communications Biology.

Solvation dynamics in a Brownian dipole lattice : a comparison between theory and computer simulation

Huan‐Xiang Zhou, B. Bagchi, M. Maroncelli, 1992 .

Dielectric and orientational relaxation in a brownian dipolar lattice

Huan‐Xiang Zhou, B. Bagchi, 1992 .

Microscopic formulation of Marcus’ theory of electron transfer

Huan‐Xiang Zhou, A. Szabó, 1995 .

Theory of Free Energy and Entropy in Noncovalent Binding

Michael K. Gilson, Huan-Xiang Zhou, M. Gilson, 2009 .

DISPLAR: an accurate method for predicting DNA-binding sites on protein surfaces

Harianto Tjong, Huan-Xiang Zhou, Huan‐Xiang Zhou, 2007, Nucleic acids research.

Contrasting factors on the kinetic path to protein complex formation diminish the effects of crowding agents.

Huan‐Xiang Zhou, Sanbo Qin, G. Schreiber, 2012, Biophysical journal.

Prediction and Dissection of Widely-Varying Association Rate Constants of Actin-Binding Proteins

Huan-Xiang Zhou, Sanbo Qin, Xiaodong Pang, 2012, PLoS Comput. Biol..

Hinge-Shift Mechanism Modulates Allosteric Regulations in Human Pin1.

Huan‐Xiang Zhou, S. Ozkan, Jingjing Guo, 2018, The journal of physical chemistry. B.

Structure Theory Two Pathways Mediate Interdomain Allosteric Regulation in Pin 1

Huan‐Xiang Zhou, Jingjing Guo, Xiaodong Pang, 2015 .

Structure of CrgA, a cell division structural and regulatory protein from Mycobacterium tuberculosis, in lipid bilayers

Huan‐Xiang Zhou, I. Hung, M. Rajagopalan, 2014, Proceedings of the National Academy of Sciences.

Diffusive reaction rates from Brownian dynamics simulations: Replacing the outer cutoff surface by an analytical treatment

J. Andrew McCammon, Huan-Xiang Zhou, Brock A. Luty, 1992 .

Binding of MgtR, a Salmonella transmembrane regulatory peptide, to MgtC, a Mycobacterium tuberculosis virulence factor: a structural study.

Huan‐Xiang Zhou, P. Fajer, Alissa Myrick, 2014, Journal of molecular biology.

Drug sensitivity, drug-resistant mutations, and structures of three conductance domains of viral porins.

Huan‐Xiang Zhou, Conggang Li, T. Cross, 2011, Biochimica et biophysica acta.

The folding transition-state ensemble of a four-helix bundle protein: helix propensity as a determinant and macromolecular crowding as a probe.

Harianto Tjong, Huan-Xiang Zhou, Huan‐Xiang Zhou, 2010, Biophysical journal.

Inverse tuning of metal binding affinity and protein stability by altering charged coordination residues in designed calcium binding proteins

Jenny J. Yang, Huan‐Xiang Zhou, Wei Yang, 2009, PMC biophysics.

Multiphase Organization Is a Second Phase Transition Within Multi-Component Biomolecular Condensates

Huan‐Xiang Zhou, Konstantinos P. Mazarakos, 2021, bioRxiv.

Liquid-Liquid Phase Separation of Patchy Particles Illuminates Diverse Effects of Regulatory Components on Protein Droplet Formation

Huan‐Xiang Zhou, V. Nguemaha, 2018, bioRxiv.

Equilibrium sampling for biomolecules under mechanical tension.

Hao Hu, Huan-Xiang Zhou, Piotr E Marszalek, 2010, Biophysical journal.

Probing the Viscoelasticity of Collagen Solutions with Optical-Tweezers-Based Microrheology

Huan‐Xiang Zhou, Weitao Yang, O. Saleh, 2011 .

Both Ligands and Macromolecular Crowders Preferentially Bind to Closed Conformations of Maltose Binding Protein.

Huan‐Xiang Zhou, Sanbo Qin, M. Yi, 2019, Biochemistry.

Intrinsically Disordered Protein Exhibits Both Compaction and Expansion under Macromolecular Crowding.

Christopher B. Stanley, Huan‐Xiang Zhou, Sanbo Qin, 2018, Biophysical journal.

A holistic approach to protein docking

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2007, Proteins.

Membrane Association and Functional Mechanism of Synaptotagmin-1 in Triggering Vesicle Fusion

Huan‐Xiang Zhou, R. Prasad, 2020, bioRxiv.

BDflex: a method for efficient treatment of molecular flexibility in calculating protein-ligand binding rate constants from brownian dynamics simulations.

Huan‐Xiang Zhou, Nicholas Greives, 2012, The Journal of chemical physics.

Theory and simulation of diffusion-influenced, stochastically gated ligand binding to buried sites.

Huan‐Xiang Zhou, J. Barreda, 2011, The Journal of chemical physics.

Kinetics of diffusion-influenced reactions studied by Brownian dynamics

Huan-Xiang Zhou, Huan‐Xiang Zhou, 1990 .

Ab initio calculations and validation of the pH-dependent structures of the His37-Trp41 quartet, the heart of acid activation and proton conductance in the M2 protein of Influenza A virus.

Huan‐Xiang Zhou, T. Cross, M. Yi, 2013, Chemical science.

A conserved glycine harboring disease-associated mutations permits NMDA receptor slow deactivation and high Ca2+ permeability

L. Wollmuth, Huan‐Xiang Zhou, Xiaoling Leng, 2018, Nature Communications.

A conserved glycine harboring disease-associated mutations is required for slow deactivation and high Ca2+ permeability in NMDA receptors

L. Wollmuth, Huan‐Xiang Zhou, Xiaoling Leng, 2018, bioRxiv.

Structural modeling for the open state of an NMDA receptor.

Huan‐Xiang Zhou, Xiaodong Pang, 2017, Journal of structural biology.

Size matters in activation/inhibition of ligand-gated ion channels.

Huan‐Xiang Zhou, Juan Du, H. Dong, 2012, Trends in pharmacological sciences.

Method to Predict Crowding Effects by Postprocessing Molecular Dynamics Trajectories: Application to the Flap Dynamics of HIV-1 Protease

J. Andrew McCammon, David D. L. Minh, Huan-Xiang Zhou, 2009, The journal of physical chemistry letters.

An NMDA receptor gating mechanism developed from MD simulations reveals molecular details underlying subunit-specific contributions.

Huan‐Xiang Zhou, Jian Dai, 2013, Biophysical journal.

Poisson-Boltzmann Calculations: van der Waals or Molecular Surface?

Huan-Xiang Zhou, Xiaodong Pang, Huan‐Xiang Zhou, 2013, Communications in computational physics.

Comparison of calculation and experiment implicates significant electrostatic contributions to the binding stability of barnase and barstar.

Huan-Xiang Zhou, Feng Dong, Huan‐Xiang Zhou, 2003, Biophysical journal.

Test of the Gouy-Chapman theory for a charged lipid membrane against explicit-solvent molecular dynamics simulations.

H. Nymeyer, Huan‐Xiang Zhou, M. Yi, 2008, Physical review letters.

Effect of macromolecular crowding on protein binding stability: modest stabilization and significant biological consequences.

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2009, Biophysical journal.

A minimum-reaction-flux solution to master-equation models of protein folding.

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2008, The Journal of chemical physics.

Distinct mechanisms of a phosphotyrosyl peptide binding to two SH2 domains.

Huan‐Xiang Zhou, Xiaodong Pang, 2014, Journal of theoretical & computational chemistry.

Disorder-to-Order Transition of an Active-Site Loop Mediates the Allosteric Activation of Sortase A.

Huan‐Xiang Zhou, Xiaodong Pang, 2015, Biophysical journal.

Reduced curvature of ligand-binding domain free-energy surface underlies partial agonism at NMDA receptors.

Huan‐Xiang Zhou, Jian Dai, 2015, Structure.

Solid-state NMR and MD simulations of the antiviral drug amantadine solubilized in DMPC bilayers.

Huan‐Xiang Zhou, Conggang Li, T. Cross, 2008, Biophysical journal.

Prediction of salt and mutational effects on the association rate of U1A protein and U1 small nuclear RNA stem/loop II.

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2008, The journal of physical chemistry. B.

Do electrostatic interactions destabilize protein-nucleic acid binding?

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2007, Biopolymers.

Association and dissociation kinetics of colicin E3 and immunity protein 3: Convergence of theory and experiment

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2003, Protein science : a publication of the Protein Society.

Disparate ionic‐strength dependencies of on and off rates in protein–protein association

Huan‐Xiang Zhou, H X Zhou, 2001, Biopolymers.

An FFT-based method for modeling protein folding and binding under crowding: benchmarking on ellipsoidal and all-atom crowders.

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2013, Journal of chemical theory and computation.

Quantitative relation between intermolecular and intramolecular binding of pro-rich peptides to SH3 domains.

Huan‐Xiang Zhou, 2006, Biophysical journal.

Atomistic Modeling of Liquid-Liquid Phase Equilibrium Explains Dependence of Critical Temperature on γ-Crystallin Sequence

Huan‐Xiang Zhou, Sanbo Qin, 2023, bioRxiv.

Simulation and modeling of crowding effects on the thermodynamic and kinetic properties of proteins with atomic details

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2013, Biophysical Reviews.

Crowding effects of membrane proteins.

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2009, The journal of physical chemistry. B.

Calculation of Second Virial Coefficients of Atomistic Proteins Using Fast Fourier Transform.

Huan‐Xiang Zhou, Sanbo Qin, 2019, The journal of physical chemistry. B.

Quantitative account of the enhanced affinity of two linked scFvs specific for different epitopes on the same antigen.

Huan‐Xiang Zhou, 2003, Journal of molecular biology.

Effects of Cholesterol on the Partitioning of a Drug Molecule in Lipid Bilayers.

Huan‐Xiang Zhou, Huihui Dong, Yuqin Yang, 2021, The journal of physical chemistry. B.

Residual charge interactions in unfolded staphylococcal nuclease can be explained by the Gaussian-chain model.

Huan‐Xiang Zhou, 2002, Biophysical journal.

The exponential nature of barrier crossings studied by langevin dynamics

Huan‐Xiang Zhou, 1989 .

Theory and simulation on the kinetics of protein-ligand binding coupled to conformational change.

Huan‐Xiang Zhou, Lu Cai, 2011, The Journal of chemical physics.

Preferential Interactions of a Crowder Protein with the Specific Binding Site of a Native Protein Complex.

Huan‐Xiang Zhou, Sanbo Qin, Z. Gong, 2022, The journal of physical chemistry letters.

Preferential interactions of a crowder protein with the specific binding site of a native protein complex

Huan‐Xiang Zhou, Sanbo Qin, Z. Gong, 2021, bioRxiv.

Accurate Calculations of Binding, Folding, and Transfer Free Energies by a Scaled Generalized Born Method.

Harianto Tjong, Huan-Xiang Zhou, Huan‐Xiang Zhou, 2008, Journal of chemical theory and computation.

Huan-Xiang Zhou, Huan‐Xiang Zhou, Xiaoqin Huang, 2006, Biophysical journal.

Theory for the rate of contact formation in a polymer chain with local conformational transitions

Huan‐Xiang Zhou, 2003 .

A method for computing association rate constants of atomistically represented proteins under macromolecular crowding

Huan‐Xiang Zhou, Sanbo Qin, Lu Cai, 2012, Physical biology.

Multidimensional reaction rate theory with anisotropic diffusion.

A. Berezhkovskii, Huan‐Xiang Zhou, A. Szabó, 2014, The Journal of chemical physics.

Gating Motions and Stationary Gating Properties of Ionotropic Glutamate Receptors: Computation Meets Electrophysiology

Huan‐Xiang Zhou, 2017, Accounts of chemical research.

M2 protein from influenza A: from multiple structures to biophysical and functional insights.

Huan‐Xiang Zhou, T. Cross, Mukesh Sharma, 2012, Current opinion in virology.

Gating mechanism of a P 2 X 4 receptor developed from normal mode analysis and molecular dynamics simulations

Huan‐Xiang Zhou, Juan Du, H. Dong, 2012 .

Prediction of protein interaction sites from sequence profile and residue neighbor list

Huan‐Xiang Zhou, Yibing Shan, 2001 .

Effect of mixed macromolecular crowding agents on protein folding

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2008, Proteins.

Fundamental aspects of protein-protein association kinetics.

Huan‐Xiang Zhou, G. Schreiber, G. Haran, 2009, Chemical reviews.

Further Development of the FFT-based Method for Atomistic Modeling of Protein Folding and Binding under Crowding: Optimization of Accuracy and Speed

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2014, Journal of chemical theory and computation.

Folding free energy surfaces of three small proteins under crowding: validation of the postprocessing method by direct simulation

Huan-Xiang Zhou, Sanbo Qin, Jeetain Mittal, 2013, Physical biology.

Unidirectional allostery in the regulatory subunit RIα facilitates efficient deactivation of protein kinase A

Huan‐Xiang Zhou, Cong Guo, 2016, Proceedings of the National Academy of Sciences.

Stabilization of proteins in confined spaces.

K A Dill, K. Dill, Huan‐Xiang Zhou, 2001, Biochemistry.

Atomistic Modeling of Intrinsically Disordered Proteins Under Polyethylene Glycol Crowding: Quantitative Comparison with Experimental Data and Implication of Protein-Crowder Attraction.

Huan-Xiang Zhou, Sanbo Qin, Huan‐Xiang Zhou, 2018, The journal of physical chemistry. B.

Atomistic Modeling of Intrinsically Disordered Proteins Under PEG Crowding: Quantitative Comparison with Experimental Data and Implication of Protein-Crowder Attraction

Huan‐Xiang Zhou, Sanbo Qin, V. Nguemaha, 2019 .

Brownian dynamics study of the influences of electrostatic interaction and diffusion on protein-protein association kinetics.

Huan‐Xiang Zhou, H. Zhou, H X Zhou, 1993, Biophysical journal.

Atomistic modeling of liquid-liquid phase equilibrium explains dependence of critical temperature on γ-crystallin sequence

Huan‐Xiang Zhou, Sanbo Qin, 2023, bioRxiv.

Power Law in a Bounded Range: Estimating the Lower and Upper Bounds from Sample Data

Huan‐Xiang Zhou, 2023, arXiv.org.

Characterizing protein kinase A (PKA) subunits as macromolecular regulators of PKA RIα liquid-liquid phase separation.

Huan‐Xiang Zhou, Sanbo Qin, Surl-Hee Ahn, 2021, Journal of Chemical Physics.

Calculating Binodals and Interfacial Tension of Phase-Separated Condensates from Molecular Simulations with Finite-Size Corrections.

Huan‐Xiang Zhou, Sanbo Qin, Konstantinos P. Mazarakos, 2023, Methods in molecular biology.

Faculty List

Michael T. Kirschenheiter, Jon A. Solworth, Ian A. Kash, 2018, International journal of urology.

Hydrodynamic friction and the capacitance of arbitrarily shaped objects.

J. Hubbard, Huan‐Xiang Zhou, J. Douglas, 1994, Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics.

Activation of signaling receptors: do ligands bind to receptor monomer, dimer, or both?

Huan‐Xiang Zhou, Xiaodong Pang, 2013, BMC biophysics.

Fuzzy Association of an Intrinsically Disordered Protein with Acidic Membranes

Huan‐Xiang Zhou, T. Cross, Alan Hicks, 2020, JACS Au.

Out-of-register parallel β-sheets and antiparallel β-sheets coexist in 150 kDa oligomers formed by Amyloid-β(1-42).

Huan‐Xiang Zhou, S. Stagg, Yuan Gao, 2020, Journal of molecular biology.

Salt Bridges Stabilize the Folded Structure of Barnase

Huan-Xiang Zhou, Huan‐Xiang Zhou, M. Vijayakumar and, 2001 .

Interaction-site prediction for protein complexes: a critical assessment

Huan‐Xiang Zhou, Sanbo Qin, 2007, Bioinform..

Full Reconstruction of a Vectorial Protein Folding Pathway by Atomic Force Microscopy and Molecular Dynamics Simulations*

Huan‐Xiang Zhou, Weitao Yang, P. Marszalek, 2010, The Journal of Biological Chemistry.

Electrostatic Interactions in Protein Structure, Folding, Binding, and Condensation.

Huan‐Xiang Zhou, Xiaodong Pang, 2018, Chemical reviews.

Electrostatic effects on the folding stability of FKBP12.

Huan‐Xiang Zhou, Harianto Tjong, J. Batra, 2016, Protein engineering, design & selection : PEDS.

Polymer crowders and protein crowders act similarly on protein folding stability

Huan‐Xiang Zhou, 2013, FEBS letters.

Rate constants and mechanisms of intrinsically disordered proteins binding to structured targets.

Huan‐Xiang Zhou, Xiaodong Pang, Cai Lu, 2012, Physical chemistry chemical physics : PCCP.

Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer

Huan‐Xiang Zhou, T. Cross, Mukesh Sharma, 2010, Science.

GBr(6): a parameterization-free, accurate, analytical generalized born method.

Huan‐Xiang Zhou, Harianto Tjong, 2007, The journal of physical chemistry. B.

Direct test of the Gaussian-chain model for treating residual charge-charge interactions in the unfolded state of proteins.

Huan-Xiang Zhou, Huan‐Xiang Zhou, 2003, Journal of the American Chemical Society.

Electrostatic contributions to T4 lysozyme stability: solvent-exposed charges versus semi-buried salt bridges.

Feng Dong, Huan‐Xiang Zhou, 2002, Biophysical journal.

Prediction of Residue−Residue Pair Frequencies in Proteins

Huan‐Xiang Zhou, M. Vijayakumar, 2000 .

Enhancement of protein-protein association rate by interaction potential: accuracy of prediction based on local Boltzmann factor.

Huan‐Xiang Zhou, H. Zhou, H. X. Zhou, 1997, Biophysical journal.

Modeling of protein conformational fluctuations in pKa predictions.

Huan‐Xiang Zhou, M. Vijayakumar, H. X. Zhou, 1997, Journal of molecular biology.

Control of reduction potential by protein matrix: lesson from a spherical protein model

Huan-Xiang Zhou, Huan‐Xiang Zhou, 1997, JBIC Journal of Biological Inorganic Chemistry.

Conformation gating as a mechanism for enzyme specificity.

J. Mccammon, Huan‐Xiang Zhou, S. Wlodek, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Conformational Heterogeneity Of The M2 Proton Channel: A Model For Channel Activation

Huan‐Xiang Zhou, T. Cross, M. Yi, 2009 .

Electrostatic recognition and induced fit in the kappa-PVIIA toxin binding to Shaker potassium channel.

Huan-Xiang Zhou, Feng Dong, Huan‐Xiang Zhou, 2005, Journal of the American Chemical Society.

The dependence of electrostatic solvation energy on dielectric constants in Poisson-Boltzmann calculations.

Huan‐Xiang Zhou, Harianto Tjong, 2006, The Journal of chemical physics.

Blind prediction of interfacial water positions in CAPRI

Julie C. Mitchell, Jeffrey J. Gray, H. Wolfson, 2014, Proteins.

Application of Biased Metropolis Algorithms: From protons to proteins

Huan-Xiang Zhou, Bernd A. Berg, Alexei Bazavov, 2010, Math. Comput. Simul..

On the calculation of diffusive reaction rates using Brownian dynamics simulations

Huan-Xiang Zhou, Huan‐Xiang Zhou, 1990 .

Nonadditive effects of mixed crowding on protein stability

Huan-Xiang Zhou, Huan‐Xiang Zhou, J. Batra, 2009, Proteins.