T. Krugh

发表

Structural features and thermodynamics of the J4/5 loop from the Candida albicans and Candida dubliniensis group I introns.

Brent M. Znosko, D. Turner, S. Kennedy, 2004, Biochemistry.

The NMR structure of an internal loop from 23S ribosomal RNA differs from its structure in crystals of 50s ribosomal subunits.

D. Turner, S. Kennedy, T. Krugh, 2006, Biochemistry.

Proton Fourier transform nmr spectroscopy in H2O solutions on a JEOL PFT-100. The WEFT, SWEFT, and VASE pulse sequences

T. Krugh, W. C. Schaefer, 1975 .

Oligonucleotide and polynucleotide — drug complexes in solution as investigated by NMR

T. Krugh, 1981 .

Structural characterization of two interchangeable conformations of a 2-aminofluorene-modified DNA oligomer by NMR and energy minimization.

T. Krugh, L. Eckel, 1994, Biochemistry.

Proton fourier-transform NMR spectroscopy in H2O solutions

T. Krugh, E. Mooberry, 1975 .

NUCLEAR MAGNETIC RESONANCE STUDIES OF DRUG-NUCLEIC ACID COMPLEXES

T. Krugh, M. Nuss, 1979 .

A comparative study of ethidium bromide complexes with dinucleotides and DNA: direct evidence for intercalation and nucleic acid sequence preferences.

T. Krugh, C. Reinhardt, 1978, Biochemistry.

Ethidium bromide–dinucleotide complexes. Evidence for intercalation and sequence preferences in binding to double‐stranded nucleic acids

T. Krugh, S. Cramer, S. Cramer, 1975, Biopolymers.

Large-scale purification of synthetic oligonucleotides and carcinogen-modified oligodeoxynucleotides on a reverse-phase polystyrene (PRP-1) column.

T. Krugh, G. J. Huang, G. Huang, 1990, Analytical biochemistry.

Ethidium bromide complexes with self-complementary deoxytetranucleotides. Demonstration and discussion of sequence preferences in the intercalative binding of ethidium bromide.

T. Krugh, R. Kastrup, M. A. Young, 1978, Biochemistry.

Interaction of drugs with Z-DNA: cooperative binding of actinomycin D or actinomine to the left-handed forms of poly(dG-dC).poly(dG-dC) and poly(dG-m5dC).poly(dG-m5dC) reverses the conformation of the helix.

G. Walker, T. Krugh, M. Stone, 1985, Biochemistry.

Ethidium binding to left-handed (Z) DNAs results in regions of right-handed DNA at the intercalation site.

G. Walker, T. Krugh, M. Stone, 1985, Biochemistry.

Drug-DNA interactions

T. Krugh, 1994 .

Solution Structure of a Nonpolar, Non-Hydrogen-Bonded Base Pair Surrogate in DNA.

K. Guckian, T. Krugh, E. Kool, 2000, Journal of the American Chemical Society.

Solution structure of a DNA duplex containing a replicable difluorotoluene–adenine pair

K. Guckian, T. Krugh, E. Kool, 1998, Nature Structural Biology.

The antitumor agent mitoxantrone binds cooperatively to DNA: evidence for heterogeneity in DNA conformation.

T. Krugh, M. Carvlin, L. S. Rosenberg, 1986, Biochemistry.

Fluorescence-detected circular dichroism of ethidium bound to poly(dG-dC) and poly(dG-m5dC) under B- and Z-form conditions.

D. Turner, G. Walker, T. Krugh, 1986, Biochemistry.

Actinomycin D-mononucleotide interactions as studied by proton magnetic resonance.

T. Krugh, J. W. Neely, 1973, Biochemistry.

Tautomerism of the nucleoside antibiotic formycin, as studied by carbon-13 nuclear magnetic resonance.

T. Krugh, 1973, Journal of the American Chemical Society.

Two-dimensional NMR studies on the anthramycin-d(ATGCAT)2 adduct.

T. Krugh, M. Stone, D. Graves, 1989, Biochemistry.

Structure of the anthramycin-d(ATGCAT)2 adduct from one- and two-dimensional proton NMR experiments in solution.

T. Krugh, M. Stone, D. Graves, 1985, Biochemistry.

The reaction of anthramycin with DNA. Proton and carbon nuclear magnetic resonance studies on the structure of the anthramycin-DNA adduct.

T. Krugh, L. Hurley, D. Graves, 1984, The Journal of biological chemistry.

Actinomycin D-deoxydinucleotide interactions as a model for binding of the drug to deoxyribonucleic acid. Proton magnetic resonance results.

T. Krugh, J. W. Neely, 1973, Biochemistry.

9 – Spin-Label-Induced Nuclear Magnetic Resonance Relaxation Studies of Enzymes

T. Krugh, 1976 .

Evidence for sequence preferences in the intercalative binding of ethidium bromide to dinucleoside monophosphates.

T. Krugh, C. Reinhardt, 1975, Journal of molecular biology.

Anisotropies and Absolute Signs of the Indirect Spin–Spin Coupling Constants in 13CH3F

T. Krugh, R. Bernheim, 1970 .

Chemical shift anisotropies from nuclear magnetic resonance studies in liquid crystals

T. Krugh, R. Bernheim, 1967 .

Actinomycin D-deoxynucleotide complexes as models for the actinomycin D-DNA complex. The use of nuclear magnetic resonance to determine the stoichiometry and the geometry of the complexes.

T. Krugh, Y. C. Chen, 1975, Biochemistry.

7‐Amino‐actinomycin D complexes with deoxynucleotides as models for the binding of the drug to DNA

T. Krugh, S. K. Sengupta, J. Hook, 1979, Biopolymers.

Nuclear magnetic resonance studies of hydrogen bonded complexes of oligonucleotides in aqueous solution. I. pdG-dC and pdG-dT.

T. Krugh, M. A. Young, 1975, Biochemical and biophysical research communications.

Actinomycin D complexes with oligonucleotides as models for the binding of the drug to DNA. Paramagnetic induced relaxation experiments on drug-nucleic acid complexes.

T. Krugh, Y. Chiao, 1977, Biochemistry.

Hydrogen-bonded complexes of the ribodinucleoside monophosphates in aqueous solution. Proton magnetic resonance studies.

T. Krugh, J. Laing, M. A. Young, 1976, Biochemistry.

Proton magnetic resonance studies of double helical oligonucleotides. The effect of base sequence on the stability of deoxydinucleotide dimers.

T. Krugh, M. A. Young, 1975, Biochemistry.

Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics.

T. Krugh, B. Hingerty, S. Broyde, 1993, Biochemistry.

Adriamycin and daunorubicin bind in a cooperative manner to deoxyribonucleic acid.

T. Krugh, D. Graves, 1983, Biochemistry.

Association of actinomycin D and deoxyribodinucleotides as a model for binding of the drug to DNA.

T. Krugh, 1972, Proceedings of the National Academy of Sciences of the United States of America.

NMR structures of (rGCUGAGGCU)2 and (rGCGGAUGCU)2: probing the structural features that shape the thermodynamic stability of GA pairs.

D. Turner, S. Schroeder, S. Kennedy, 2007, Biochemistry.

Nuclear magnetic resonance spectroscopy and molecular modeling reveal that different hydrogen bonding patterns are possible for G.U pairs: one hydrogen bond for each G.U pair in r(GGCGUGCC)(2) and two for each G.U pair in r(GAGUGCUC)(2).

D. Turner, R. Kierzek, T. Krugh, 2000, Biochemistry.

Proximity of the nucleoside monophosphate and triphosphate binding sites on deoxyribonucleic acid polymerase.

T. Krugh, 1971, Biochemistry.

2–Aminofluorene modified DNA duplex exists in two interchangeable conformations

T. Krugh, L. Eckel, 1994, Nature Structural Biology.

N-acetoxy-2-acetylaminofluorene modification of a deoxyoligonucleotide duplex.

T. Krugh, D. Sanford, 1985, Nucleic acids research.

Equilibrium binding of carcinogens and antitumor antibiotics to DNA: site selectivity, cooperativity, allosterism

S. A. Winkle, T. R. Krugh, T. Krugh, 1981, Nucleic Acids Res..

Structural characterization of a (+)-trans-anti-benzo[a]pyrene-DNA adduct using NMR, restrained energy minimization, and molecular dynamics.

T. Krugh, M. Fountain, 1995, Biochemistry.

Structural features of a six-nucleotide RNA hairpin loop found in ribosomal RNA.

D. Turner, M. Serra, T. Krugh, 1996, Biochemistry.

Single-cell partition analysis--a direct fluorescence technique for examining ligand-macromolecule interactions.

T. Krugh, D. Graves, 1983, Analytical biochemistry.

Analysis of site-specific binding of (+/-)-anti-benzo[a]pyrene diol epoxide to restriction fragments of pBR322 DNA via photochemical mapping.

T. Krugh, K. Dittrich, 1991, Chemical research in toxicology.

Phosphorus-31 nuclear magnetic resonance studies of actinomycin D, ethidium bromide, and 9-aminoacridine complexes with dinucleotides.

T. Krugh, C. Reinhardt, 1977, Biochemistry.

Proton and 19F Magnetic Resonance of Partially Oriented Fluoromethanes

T. Krugh, D. J. Hoy, R. Bernheim, 1969 .

Resolution of electronic absorption bands and nucleotide binding processes in actinomycin D

T. Krugh, H. Auer, Y. Chiao, 1978 .

Proton magnetic resonance studies of actinomycin D complexes with mixtures of nucleotides as models for the binding of the drug to DNA.

T. Krugh, E. Mooberry, Y. Chiao, 1977, Biochemistry.

Measurement of relaxation times by the adiabatic half passage (T1ϱ) technique

T. Krugh, J. W. Neely, 1973 .

NMR reveals the absence of hydrogen bonding in adjacent UU and AG mismatches in an isolated internal loop from ribosomal RNA.

D. Turner, D. Mathews, T. Xia, 2007, Biochemistry.

On the cooperative and noncooperative binding of ethidium to DNA.

T. Krugh, L. S. Rosenberg, S. Winkle, 1982, Nucleic acids research.

Solution structure of an RNA internal loop with three consecutive sheared GA pairs.

Brent M. Znosko, Brent M Znosko, Scott D Kennedy, 2005, Biochemistry.

Spectroscopic Studies of Drug Nucleic Acid Complexes

T. Krugh, J. Hook, S. Lin, 1979 .

Daunorubicin and adriamycin facilitate actinomycin D binding to poly(dA–dT)·poly(dA–dT)

T. Krugh, M. A. Young, THOMAS R. KRUGH, 1977, Nature.

Structural characterization of a six-nucleotide RNA hairpin loop found in Escherichia coli, r(UUAAGU).

T. Krugh, Hong Zhang, Matthew A. Fountain, 2001, Biochemistry.