R. Uppoor

发表

In vivo drug‐drug interaction studies‐ A survey of all new molecular entities approved from 1987 to 1997

L. Lesko, P. Marroum, R. Uppoor, 2000, Clinical pharmacology and therapeutics.

The Use of Imaging in the Early Development of Neuropharmacological Drugs: A Survey of Approved NDAs

A G Sorensen, A. Sorensen, R. Uppoor, 2008, Clinical pharmacology and therapeutics.

An Innovative Pharmacometric Approach for the Simultaneous Analysis of Frequency, Duration and Severity of Migraine Events

R. Uppoor, M. Mehta, A. Pérez‐Pitarch, 2020, Pharmaceutical Research.

Biowaiver and Biopharmaceutics Classification System

Lawrence X. Yu, R. Uppoor, M. Mehta, 2014 .

Regulatory Considerations for Oral Extended Release Dosage Forms and in vitro (Dissolution)/in vivo (Bioavailability) Correlations

P. Marroum, R. Uppoor, 2004 .

Assessment of Similarity in Antipsychotic Exposure‐Response Relationships in Clinical Trials Between Adults and Adolescents With Acute Exacerbation of Schizophrenia

R. Uppoor, I. Younis, Hao Zhu, 2020, Journal of clinical pharmacology.

Application of Clinical Pharmacology Principles in Drug Development of Modified‐Release Products: Leveraging Exposure‐Response Information to Support Approval

R. Uppoor, M. Mehta, Mariam A. Ahmed, 2020, Journal of clinical pharmacology.

FIP/AAPS guidelines to dissolution/in vitro release testing of novel/special dosage forms

Cynthia K. Brown, John C. Kraemer, J. Crison, 2008, AAPS PharmSciTech.

Clinical Pharmacology in Drug Development for Rare Diseases in Neurology: Contributions and Opportunities

R. Uppoor, M. Mehta, S. Sabarinath, 2021, Clinical pharmacology and therapeutics.

Essential Pharmacokinetic Information for Drug Dosage Decisions: A Concise Visual Presentation in the Drug Label

N. Stockbridge, L. Lesko, R. Uppoor, 2011, Clinical pharmacology and therapeutics.

Improving Pediatric Dosing Through Pediatric Initiatives: What We Have Learned

Shiew-Mei Huang, R. Uppoor, D. Murphy, 2008, Pediatrics.

Development and Internal Validation of an In Vitro-in Vivo Correlation for a Hydrophilic Metoprolol Tartrate Extended Release Tablet Formulation

Patrick Marroum, P. Marroum, R. Uppoor, 1998, Pharmaceutical Research.

Evaluation of "external" predictability of an in vitro-in vivo correlation for an extended-release formulation containing metoprolol tartrate.

A S Hussain, L L Augsburger, P. Marroum, 2000, Journal of pharmaceutical sciences.

Use of Partial Area Under the Curve in Bioavailability or Bioequivalence Assessments: A Regulatory Perspective

Lei Zhang, R. Uppoor, R. Lionberger, 2021, Clinical pharmacology and therapeutics.

Partial Area Under the Curve: An Additional Pharmacokinetic Metric for Bioavailability and Bioequivalence Assessments

Lawrence X. Yu, R. Uppoor, Hao Zhu, 2014 .

Use of Partial Area under the Curve Metrics to Assess Bioequivalence of Methylphenidate Multiphasic Modified Release Formulations

Lawrence X. Yu, R. Uppoor, R. Lionberger, 2012, The AAPS Journal.

The Trend of Increasing Placebo Response and Decreasing Treatment Effect in Schizophrenia Trials Continues: An Update From the US Food and Drug Administration.

R. Uppoor, Hao Zhu, M. Gopalakrishnan, 2020, The Journal of clinical psychiatry.

Pharmacometric Bridging Approach for U.S. Food and Drug Administration Approval and Identification of Topiramate Dosing Regimen for Pediatric Patients 2-9 Years of Age With Epilepsy.

R. Uppoor, Yaning Wang, M. Mehta, 2019, Journal of pharmaceutical sciences.

Summary workshop report: biopharmaceutics classification system--implementation challenges and extension opportunities.

Mei-Ling Chen, Guohua Zhang, Lawrence X. Yu, 2004, Journal of pharmaceutical sciences.

In vitro metabolic interaction studies: Experience of the Food and Drug Administration

Patrick Marroum, L. Lesko, P. Marroum, 1999, Clinical pharmacology and therapeutics.

Impact of pharmacometrics on drug approval and labeling decisions: A survey of 42 new drug applications

Yaning Wang, Jogarao V. S. Gobburu, P. Marroum, 2005, The AAPS Journal.

Exposure–response analyses of blood pressure and heart rate changes for methylphenidate in healthy adults

R. Uppoor, Hao Zhu, Yaning Wang, 2017, Journal of Pharmacokinetics and Pharmacodynamics.

Association of End Point Definition and Randomized Clinical Trial Duration in Clinical Trials of Schizophrenia Medications.

R. Uppoor, Hao Zhu, M. Gopalakrishnan, 2020, JAMA psychiatry.

Effect of Ethanol on Opioid Drug Permeability Through Caco-2 Cell Monolayers

M. Khan, R. Uppoor, C. D. Ellison, 2008, The AAPS Journal.

Extrapolation of Efficacy from Adults to Pediatric Patients of Drugs for Treatment of Partial Onset Seizures: A Regulatory Perspective

B. Dunn, R. Uppoor, E. Bastings, 2022, Clinical pharmacology and therapeutics.

Chapter 14 – Bioavailability and Bioequivalence*

Lawrence X. Yu, R. Uppoor, Hao Zhu, 2017 .

A Quantitative Justification of Similarity in Placebo Response Between Adults and Adolescents With Acute Exacerbation of Schizophrenia in Clinical Trials

R. Uppoor, Hao Zhu, M. Gopalakrishnan, 2019, Clinical pharmacology and therapeutics.

Extrapolation of Efficacy and Dose Selection in Pediatrics: A Case Example of Atypical Antipsychotics in Adolescents With Schizophrenia and Bipolar I Disorder

R. Uppoor, Hao Zhu, Yaning Wang, 2021, Journal of clinical pharmacology.

A Proposal of Conducting Bioequivalence Trials with Gastric pH Modulators for Two Oral Formulations Demonstrating Different Dissolution Profiles at Elevated pH

R. Uppoor, Hao Zhu, Yaning Wang, 2019, Clinical and Translational Science.