K. Rose

发表

Analytical biotechnology: Qualitative and semi-quantitative protein analysis: the gold rush is still on, but the dust is settling

K. Rose, 2004 .

A Stable Isotope Dilution Assay for the In Vivo Determination of Insulin Levels in Humans by Mass Spectrometry

K. Rose, A. Kippen, R. Offord, 1997, Diabetes.

In vitro and in silico processes to identify differentially expressed proteins

Patricia Rodriguez-Tomé, Eduardo Gonzalez-Couto, Catherine Jeandenans, 2004, Proteomics.

Characterization of five genes in the upper-pathway operon of TOL plasmid pWW0 from Pseudomonas putida and identification of the gene products

M. Wubbolts, S. Harayama, K. Timmis, 1989, Journal of bacteriology.

Toward a clinical molecular scanner for proteome research: parallel protein chemical processing before and during western blot.

D F Hochstrasser, D. Hochstrasser, K. Rose, 1999, Analytical chemistry.

Conformation-directed recombination of enzyme-activated peptide fragments: a simple and efficient means to protein engineering. Its use in the creation of cytochrome c analogues for structure-function studies.

K. Rose, A. Proudfoot, C. Wallace, 1989, The Journal of biological chemistry.

Purification and characterization of human interleukin‐1β expressed in recombinant Escherichia coli

P. Wingfield, J. Tavernier, K. Rose, 1986 .

Characterization of factors that direct transcription of rat ribosomal DNA

S. Smith, K. Rose, H. Yang-Yen, 1990, Molecular and cellular biology.

Stepwise Solid-Phase Synthesis of Polyamides as Linkers

K. Rose, J. Vizzavona, 1999 .

Molecular Scanner Development

D. Hochstrasser, K. Rose, W. Bienvenut, 2005 .

Construction of protein analogues by site-specific condensation of unprotected fragments.

K. Rose, R. Offord, H. Gaertner, 1992, Bioconjugate chemistry.

C-terminal peptide identification by fast atom bombardment mass spectrometry.

P. Wingfield, K. Rose, R. Offord, 1988, The Biochemical journal.

Characterization of new multimeric erythropoietin receptor agonists

K. Rose, O. Hartley, O. Vadas, 2008, Biopolymers.

Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1

N. Patel, K. Rose, A. Ahluwalia, 2017, Scientific Reports.

Elimination of free radionuclide by a chelating agent improves tumor-to-nontumor ratios following radioimmunotargeting with antibody labeled with 67Ga.

K. Rose, R. Offord, J. Ryser, 1998, Nuclear medicine and biology.

Characterization of two post-translationally processed forms of human serum retinol-binding protein: altered ratios in chronic renal failure.

J. Saurat, K. Rose, S. Jaconi, 1995, Journal of lipid research.

Des-(27-31)C-Peptide

P. Halban, K. Rose, S. Kahn, 1996, The Journal of Biological Chemistry.

Facile synthesis of homogeneous artificial proteins

K. Rose, 1994 .

Multivalency—a way to enhance binding avidities and bioactivity—preliminary applications to EPO

K. Rose, O. Vadas, 2007, Journal of peptide science : an official publication of the European Peptide Society.

Polyethyleneglycol-based chains of precise length for chemobodies

K. Rose, J. Vizzavona, 2002 .

Totally synthetic lipid-containing polyoxime peptide constructs are potent immunogens.

K. Rose, L. Brown, D. Jackson, 2000, Vaccine.

New cyclization reaction at the amino terminus of peptides and proteins.

K. Rose, W. Zeng, U. Burger, 1999, Bioconjugate chemistry.

Use of Fmoc-N-(2-hydroxy-4-methoxybenzyl)amino acids in peptide synthesis.

K. Rose, P. Regamey, W. Zeng, 2009, The journal of peptide research : official journal of the American Peptide Society.

Natural peptides as building blocks for the synthesis of large protein-like molecules with hydrazone and oxime linkages.

K. Rose, I. Chernushevich, K. Standing, 1996, Bioconjugate chemistry.

Polyoximes: A flexible approach for producing homogeneous artificial proteins

K. Rose, W. Zeng, D. C. Jackson, 1995 .

A synthetic peptide-based polyoxime vaccine construct of high purity and activity.

K. Rose, L. Brown, D. Jackson, 1995, Molecular immunology.

Site-specific religation of G-CSF fragments through a thioether bond.

K. Rose, R. Offord, H. Gaertner, 1994, Bioconjugate chemistry.

Facile identification by electrospray mass spectrometry of the insulin fragment A14-21-B17-30 produced by insulin proteinase.

K. Rose, R. Offord, R. Stöcklin, 1993, Rapid communications in mass spectrometry : RCM.

Positive and Negative Labeling of Human Proinsulin, Insulin, and C-Peptide with Stable Isotopes

K. Rose, R. Offord, R. Stöcklin, 2000 .

Development of a gas chromatography mass spectrometry assay for the two eosinophil chemotactic factors of anaphylaxis.

K. Rose, J. Priddle, A. Mallet, 1983, Biomedical mass spectrometry.

Purification and characterization of human interleukin‐1α produced in Escherichia coli

P. Wingfield, K. Rose, J. Dayer, 1987 .

High yield, site-specific coupling of N-terminally modified beta-lactamase to a proteolytically derived single-sulfhydryl murine Fab'.

K. Rose, R. Offord, J. J. Starling, 1994, Bioconjugate chemistry.

Covalent capture: a new tool for the purification of synthetic and recombinant polypeptides.

K. Rose, M. Villain, J. Vizzavona, 2001, Chemistry & biology.

Identification of radioactive insulin fragments liberated by insulin proteinase during the degradation of semisynthetic [3H]GlyA1]insulin and [3H]PheB1]insulin.

K. Rose, R. Offord, J. G. Davies, 1988, The Biochemical journal.

Identification by fast atom bombardment mass spectrometry of insulin fragments produced by insulin proteinase.

R. M. Jones, K. Rose, R. Offord, 1988, The Biochemical journal.

Purification of recA-based fusion proteins by immunoadsorbent chromatography. Characterization of a major antigenic determinant of Escherichia coli recA protein.

K. Rose, K. Glenn, M. Bittner, 1985, The Journal of biological chemistry.

Preparation of well-defined protein conjugates using enzyme-assisted reverse proteolysis.

R. M. Jones, K. Rose, R. Offord, 1991, Bioconjugate chemistry.

Preparation of a trivalent antigen-binding construct using polyoxime chemistry: improved biodistribution and potential for therapeutic application.

K. Rose, R. Offord, P. Schubiger, 1996, Cancer research.

Preparation and characterization of bovine growth hormones produced in recombinant Escherichia coli.

P. Wingfield, K. Rose, G. Buell, 1987, The Biochemical journal.

Affinity technique for the isolation of polypeptides containing arginine modified with cyclohexane-1,2-dione, and their analysis by combined gas-liquid chromatography-mass spectrometry

K. Rose, R. Offord, J. Priddle, 1981 .

Protein conjugates of defined structure: synthesis and use of a new carrier molecule.

K. Rose, R. Offord, Cynthia L. Nichols, 1993, Bioconjugate chemistry.

Short-term insulin-induced glycogen formation in primary hepatocytes as a screening bioassay for insulin action.

K. Rose, A. Kippen, R. Offord, 1998, Analytical biochemistry.

Characterization ofFactors ThatDirect Transcription of

S. Smith, K. Rose, H. Yang-Yen, 1990 .

Preparation and analysis of the nucleocapsid proteins of vesicular stomatitis virus and sendai virus, and analysis of the sendai virus leader-NP gene region.

K. Rose, C. Giorgi, D. Kolakofsky, 1984, The Journal of general virology.

Analysis oftheSendai Virus M GeneandProtein

K. Rose, C. Giorgi, L. Roux, 1984 .

Colon carcinoma immunoscintigraphy by monoclonal anti-CEA antibody labeled with gallium-67-aminooxyacetyldeferroxamine.

R. M. Jones, K. Rose, A. Kurt, 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Characterization of recombinant-derived granulocyte-colony stimulating factor (G-CSF).

G. Turcatti, P. Wingfield, K. Rose, 1988, The Biochemical journal.

[mono[125I]iodo-Tyr10,MetO17]-vasoactive intestinal polypeptide. Preparation, characterization, and use for radioimmunoassay and receptor binding.

P. Magistretti, K. Rose, G. J. Hughes, 1986, The Journal of biological chemistry.

Chemo-enzymic backbone engineering of proteins. Site-specific incorporation of synthetic peptides that mimic the 64-74 disulfide loop of granulocyte colony-stimulating factor.

K. Rose, R. Offord, H. Gaertner, 1994, The Journal of biological chemistry.

Site-specific conjugation of an enzyme and an antibody fragment.

K. Rose, D. Blakey, R. Offord, 1994, Bioconjugate chemistry.

The secalosides, novel tumor cell growth inhibitory glycosides from a pollen extract.

C. Fankhauser, K. Rose, F. Sirotnak, 1997, Journal of natural products.

Purification and characterization of a methionine-specific aminopeptidase from Salmonella typhimurium.

G. Turcatti, P. Wingfield, K. Rose, 1989, European journal of biochemistry.

Redesigning metabolic routes: manipulation of TOL plasmid pathway for catabolism of alkylbenzoates.

K. Timmis, J. Ramos, K. Rose, 1987, Science.

Isolation and characterization of a cyclic hydroxamic acid from a pollen extract, which inhibits cancerous cell growth in vitro.

K. Rose, F. Habib, U. Burger, 1995, Journal of medicinal chemistry.

Enzymatic semisynthesis of insulin specifically labelled with tritium at position B-30.

K. Rose, R. Offord, C. Bradshaw, 1987, Protein engineering.

Amino acid sequence determination by g.l.c.--mass spectrometry of permethylated peptides. Optimization of the formation of chemical derivatives at the 2-10 nmol level.

K. Rose, R. Offord, M. Simona, 1983, The Biochemical journal.

Development of an Isotope Dilution Assay for Precise Determination of Insulin, C-peptide, and Proinsulin Levels in Non-diabetic and Type II Diabetic Individuals with Comparison to Immunoassay*

K. Rose, A. Kippen, R. Offord, 1997, The Journal of Biological Chemistry.

Revised amino acid sequence of pancreatic spasmolytic polypeptide exhibits greater similarity with an inducible pS2 peptide found in a human breast cancer cell line.

K. Rose, L. Thim, L. Savoy, 1989, Biochimica et biophysica acta.

Chromatofocusing of N-terminally processed forms of proteins. Isolation and characterization of two forms of interleukin-1 beta and of bovine growth hormone.

P. Wingfield, K. Rose, P. Graber, 1987, Journal of chromatography.

A new mass-spectrometric C-terminal sequencing technique finds a similarity between gamma-interferon and alpha 2-interferon and identifies a proteolytically clipped gamma-interferon that retains full antiviral activity.

K. Rose, R. Offord, D. Thatcher, 1983, The Biochemical journal.

Discovery of proteins related to coronary artery disease using industrial-scale proteomics analysis of pooled plasma.

Denis Hochstrasser, Peter Sinnaeve, Jacky Vonderscher, 2006, American heart journal.

Industrial‐scale proteomics: From liters of plasma to chemically synthesized proteins

D. Hochstrasser, A. Bairoch, J. Colinge, 2004, Proteomics.

Insulin proteinase liberates from glucagon a fragment known to have enhanced activity against Ca2+ + Mg2+-dependent ATPase.

G. Turcatti, K. Rose, R. Offord, 1988, The Biochemical journal.

Characterization of human interleukin 2 derived from Escherichia coli.

K. Rose, S. Liang, C. Liang, 1985, The Biochemical journal.

Fructose-1,6-bisphosphate aldolase from Drosophila melanogaster: primary structure analysis, secondary structure prediction, and comparison with vertebrate aldolases.

K. Rose, A. Honegger, O. Brenner-Holzach, 1988, Archives of biochemistry and biophysics.

Simple and effective direct coupling for gas chromatography-mass spectrometry on the MS 50 mass spectrometer

K. Rose, 1983 .

Amino acid sequence determination by gas chromatography—mass spectrometry of permethylated peptides

A. Bairoch, K. Rose, R. Offord, 1983 .

A mass-spectrometric method for the estimation of the ratio of gamma-carboxyglutamic acid to glutamic acid at specific sites in proteins. Application to the N-terminal region of bovine prothrombin.

K. Rose, R. Offord, J. Priddle, 1980, The Biochemical journal.

Overview of the Characterization of Recombinant Proteins

P. Wingfield, K. Rose, N. Denslow, 1995, Current protocols in protein science.

Analysis of the Sendai virus M gene and protein

K. Rose, C. Giorgi, D. Kolakofsky, 1984, Journal of virology.

Sequence determination of the Sendai virus fusion protein gene.

K. Rose, C. Giorgi, D. Kolakofsky, 1985, The Journal of general virology.

Partial characterization of natural and recombinant human soluble CD23.

G. Turcatti, K. Rose, P. Regamey, 1992, The Biochemical journal.

Determining the Identity and Structure of Recombinant Proteins

K. Rose, P. Righetti, N. Denslow, 1996, Current protocols in protein science.

Effective depletion of albumin using a new peptide‐based affinity medium

L. Bougueleret, K. Rose, T. Baussant, 2005, Proteomics.

Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1

N. Patel, K. Rose, A. Ahluwalia, 2017, Scientific Reports.

Rapid preparation of human insulin and insulin analogues in high yield by enzyme-assisted semi-synthesis.

K. Rose, R. Offord, H. De Pury, 1983, The Biochemical journal.

The preparation of porcine (Tyr-A14-2H) insulin and its characterization by mass spectrometry.

K. Rose, P. Vuagnat, K. Kovács, 1988, Protein engineering.

Characterization ofFiveGenesintheUpper-Pathway Operonof TOLPlasmid pWWO fromPseudomonas putida and Identification oftheGeneProducts

M. Wubbolts, S. Harayama, K. Rose, 1989 .

A novel derivative of the chelon desferrioxamine for site‐specific conjugation to antibodies

K. Rose, R. Offord, J. Ryser, 1989, International journal of cancer.

A novel method for the rational construction of well-defined immunogens: the use of oximation to conjugate cholera toxin B subunit to a peptide-polyoxime complex.

K. Rose, R. Offord, W. Zeng, 2003, Bioconjugate chemistry.

Characterization of human and mouse granulocyte-macrophage-colony-stimulating factors derived from Escherichia coli.

P. Wingfield, K. Rose, M. Simona, 1987, The Biochemical journal.

Cysteine-reactive covalent capture tags for enrichment of cysteine-containing peptides.

K. Rose, L. Dayon, Jean-Charles Sanchez, 2009, Rapid communications in mass spectrometry : RCM.

Enrichment of N-terminal cysteinyl-peptides by covalent capture.

K. Rose, L. Dayon, Jean-Charles Sanchez, 2009, Journal of proteomics.

Site-specific modification of a fragment of a chimeric monoclonal antibody using reverse proteolysis.

K. Rose, R. Offord, I. Fisch, 1992, Bioconjugate chemistry.

Reverse proteolysis as a means of introducing non-coded changes into proteins

K. Rose, R. Offord, H. Gaertner, 1993 .

PRESS-STUD PROTEIN CONJUGATES

K. Rose, R. Offord, S. Pochon, 1987 .