F. Bressolle

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Plasma and salivary pharmacokinetics of 5-fluorouracil (5-FU) in patients with metastatic colorectal cancer receiving 5-FU bolus plus continuous infusion with high-dose folinic acid.

J. M. Joulia, F. Pinguet, M. Ychou, 1999, European journal of cancer.

A LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY METHOD FOR THE SIMULTANEOUS DETERMINATION OF CAPECITABINE, 5′-DEOXY-5-FLUOROCYTIDINE, 5′-DEOXY-5-FLUOROURIDINE, 5-FLUOROURACIL, AND 5-FLUORODIHYDROURACIL IN HUMAN PLASMA

F. Pinguet, M. Ychou, F. Bressolle, 2010 .

Combination paclitaxel and vinorelbine therapy: in vitro cytotoxic interactions and dose-escalation study in breast cancer patients previously exposed to anthracyclines.

S. Culine, F. Pinguet, F. Bressolle, 1999, International journal of oncology.

Characterization of a new anticancer agent, EAPB0203, and its main metabolites: nuclear magnetic resonance and liquid chromatography-mass spectrometry studies.

F. Bressolle, C. Enjalbal, B. Banaigs, 2012, Analytical chemistry.

Quantitation of imidazo[1,2-a]quinoxaline derivatives in human and rat plasma using LC/ESI-MS.

F. Pinguet, F. Bressolle, I. Solassol, 2009, Journal of separation science.

Methyl-beta-cyclodextrin and doxorubicin pharmacokinetics and tissue concentrations following bolus injection of these drugs alone or together in the rabbit.

J. M. Joulia, F. Pinguet, F. Bressolle, 1999, International journal of pharmaceutics.

Antiproliferative effect of methyl-beta-cyclodextrin in vitro and in human tumour xenografted athymic nude mice.

F. Pinguet, F. Bressolle, P. Grosse, 1998, British Journal of Cancer.

High-performance liquid chromatographic assay for methyl-beta-cyclodextrin in plasma and cell lysate.

J. M. Joulia, F. Pinguet, C. Astre, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Methyl-β-cyclodextrin in HL-60 parental and multidrug-resistant cancer cell lines: effect on the cytotoxic activity and intracellular accumulation of doxorubicin

F. Pinguet, F. Bressolle, P. Grosse, 1997, Cancer Chemotherapy and Pharmacology.

Cyclodextrins and enantiomeric separations of drugs by liquid chromatography and capillary electrophoresis: basic principles and new developments.

F. Bressolle, M. Audran, J. Vallon, 1996, Journal of chromatography. B, Biomedical applications.

Sensitive HPLC-fluorescence method for irinotecan and four major metabolites in human plasma and saliva: application to pharmacokinetic studies.

S. Culine, F. Pinguet, M. Ychou, 2003, Clinical chemistry.

Methotrexate pharmacokinetics in childhood acute lymphoblastic leukaemia: a prognostic value ?

F. Bressolle, G. Margueritte, J. Daures, 2011, Journal of clinical pharmacy and therapeutics.

Moxisylyte: A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in impotence

F. Bressolle, C. Marquer, 1998, Fundamental & clinical pharmacology.

Liquid chromatography-electrospray mass spectrometry determination of carbamazepine, oxcarbazepine and eight of their metabolites in human plasma.

F. Bressolle, D. Hillaire‐buys, H. Peyrière, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Bayesian estimate of vinorelbine pharmacokinetic parameters in elderly patients with advanced metastatic cancer.

S. Culine, F. Pinguet, C. Astre, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Individual 5-FU dose adaptation in metastatic colorectal cancer: results of a phase II study using a bimonthly pharmacokinetically intensified LV5FU2 regimen

F. Pinguet, M. Ychou, J. Duffour, 2003, Cancer Chemotherapy and Pharmacology.

Metabolism and Pharmacokinetics of EAPB0203 and EAPB0503, Two Imidazoquinoxaline Compounds Previously Shown to Have Antitumoral Activity on Melanoma and T-Lymphomas

F. Pinguet, F. Bressolle, J. Cooper, 2010, Drug Metabolism and Disposition.

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F. Pinguet, F. Bressolle, J. Cooper, 2010 .

Rapid resolution liquid chromatography-mass spectrometry determination of SAR97276 in monkey matrices. Pharmacokinetics in rhesus monkey infected by Plasmodium cynomolgi.

H. Vial, F. Bressolle, C. Kocken, 2009, Journal of pharmaceutical and biomedical analysis.

Quantitation of SAR97276 in mouse tissues by rapid resolution liquid chromatography-mass spectrometry.

H. Vial, F. Bressolle, Florence Gattacceca, 2009, Journal of separation science.

Quantitative analysis of a bis-thiazolium antimalarial compound, SAR97276, in mouse plasma and red blood cell samples, using liquid chromatography mass spectrometry.

H. Vial, F. Bressolle, D. Margout, 2008, Journal of pharmaceutical and biomedical analysis.

Pharmacological Properties of a New Antimalarial Bisthiazolium Salt, T3, and a Corresponding Prodrug, TE3

H. Vial, F. Bressolle, O. Nicolas, 2005, Antimicrobial Agents and Chemotherapy.

Stability of ready-to-use temsirolimus infusion solution (100mg/L) in polypropylene containers under different storage conditions.

F. Pinguet, F. Bressolle, I. Solassol, 2012, Annales pharmaceutiques francaises.

Determination of perfluorodecalin and perfluoro-N-methylcyclohexylpiperidine in rat blood by gas chromatography-mass spectrometry.

F. Bressolle, M. Audran, M. Krafft, 2000, Journal of chromatography. B, Biomedical sciences and applications.

Distribution of ibogaine and noribogaine in a man following a poisoning involving root bark of the Tabernanthe iboga shrub.

F. Bressolle, E. Baccino, O. Mathieu, 2006, Journal of analytical toxicology.

Population pharmacokinetics of cisplatin in patients with advanced ovarian cancer during intraperitoneal hyperthermia chemotherapy.

F. Bressolle, F. Gilly, M. Guillaumont, 2002, Anticancer research.

Biodistribution of doxorubicin-alkylated poly(L-lysine citramide imide) conjugates in an experimental model of peritoneal carcinomatosis after intraperitoneal administration.

F. Pinguet, F. Bressolle, P. Colombo, 2007, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Pharmacokinetics of high-dose intravenous melphalan in patients undergoing peripheral blood hematopoietic progenitor-cell transplantation.

S. Culine, F. Pinguet, C. Astre, 1997, Anticancer Research.

Inter- and Intraindividual Variabilities in Pharmacokinetics of Fentanyl After Repeated 72-Hour Transdermal Applications in Cancer Pain Patients

S. Culine, F. Pinguet, F. Bressolle, 2005, Therapeutic drug monitoring.

A liquid chromatography-mass spectrometry assay for simultaneous determination of two antimalarial thiazolium compounds in human and rat matrices.

H. Vial, F. Bressolle, D. Margout, 2008, Journal of pharmaceutical and biomedical analysis.

Clozapine and Metabolite Concentrations during Treatment of Patients with Chronic Schizophrenia

F. Bressolle, J. Kinowski, F. Bressolle, 1999, Journal of clinical pharmacology.

New imidazo[1,2-a]quinoxaline derivatives: synthesis and in vitro activity against human melanoma.

F. Pinguet, F. Bressolle, S. Khier, 2009, European journal of medicinal chemistry.

In vitro cytotoxic effect of melphalan and pilot phase II study in hormone-refractory prostate cancer.

S. Culine, F. Pinguet, F. Bressolle, 2006, Anticancer research.

Stability of the ready-to-use solutions of eribulin for intravenous infusion.

F. Pinguet, F. Bressolle, S. Poujol, 2012, Annales pharmaceutiques francaises.

A phase I and pharmacokinetic study of melphalan using a 24-hour continuous infusion in patients with advanced malignancies.

S. Culine, F. Pinguet, C. Astre, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Quantitative determination of rocuronium in human plasma by liquid chromatography-electrospray ionization mass spectrometry.

F. Bressolle, C. Enjalbal, M. Audran, 2001, Journal of chromatography. A.

Pharmacokinetic‐Pharmacodynamic Modeling of Atracurium in Intensive Care Patients

F. Bressolle, M. Audran, J. Lefrant, 2001, Journal of clinical pharmacology.

High-performance liquid chromatographic method for the determination of atracurium and laudanosine in human plasma. Application to pharmacokinetics.

F. Bressolle, M. Audran, J. Lefrant, 1999, Journal of chromatography. B, Biomedical sciences and applications.

Determination of clozapine and its major metabolites in human plasma and red blood cells by high-performance liquid chromatography with ultraviolet absorbance detection.

F. Bressolle, J. Kinowski, R. Aznar, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Simple high-performance liquid chromatographic separation of oxazepam and its diastereoisomeric glucuronides in serum. Applications in a pharmacokinetic study in sheep.

F. Bressolle, M. Gagnieu, J. Vallon, 1996, Journal of chromatography. B, Biomedical applications.

SENSITIVE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC FLUORESCENCE DETERMINATION OF TOPOTECAN IN HUMAN PLASMA AND PAROTID SALIVA

F. Pinguet, C. Astre, F. Bressolle, 2000 .

A limited sampling strategy to estimate the pharmacokinetic parameters of irinotecan and its active metabolite, SN-38, in patients with metastatic digestive cancer receiving the FOLFIRI regimen.

F. Pinguet, M. Ychou, J. Duffour, 2007, Oncology reports.

Multiple-dose pharmacokinetics of clozapine in patients with chronic schizophrenia.

F. Bressolle, J. Kinowski, F. Bressolle, 1998, Journal of clinical psychopharmacology.

High-performance liquid chromatographic determination of fluconazole in plasma.

F. Bressolle, M. Cociglio, R. Alric, 1996, Journal of chromatography. B, Biomedical applications.

Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials.

H. Vial, F. Bressolle, T. Durand, 2019, Bioorganic & medicinal chemistry letters.

In vitro and in vivo anti-tumoral activities of imidazo[1,2-a]quinoxaline, imidazo[1,5-a]quinoxaline, and pyrazolo[1,5-a]quinoxaline derivatives.

F. Pinguet, F. Bressolle, P. Bonnet, 2008, Bioorganic & medicinal chemistry.

Determination of 5-fluorouracil and its main metabolites in plasma by high-performance liquid chromatography: application to a pharmacokinetic study.

J. M. Joulia, F. Pinguet, C. Astre, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Thin layer chromatography reflectometric determination of benzoic and sorbic acids in fruit beverages.

F. Bressolle, B. Mandrou, 1980, Journal - Association of Official Analytical Chemists.

Arsenic speciation in humans and food products: a review.

F. Bressolle, J. Vallon, L. Benramdane, 1999, Journal of chromatographic science.

Validation of liquid chromatographic and gas chromatographic methods. Applications to pharmacokinetics.

F. Bressolle, M. Audran, M Audran, 1996, Journal of chromatography. B, Biomedical applications.

Simultaneous determination of dexamethasone and 6 beta-hydroxydexamethasone in urine using solid-phase extraction and liquid chromatography: applications to in vivo measurement of cytochrome P450 3A4 activity.

S. Culine, F. Pinguet, F. Bressolle, 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Problems and applications of reversed-phase thin-layer chromatography

A. Siouffi, G. Guiochon, F. Bressolle, 1979 .

Stability of amphotericin B and nystatin in antifungal mouthrinses containing sodium hydrogen carbonate.

F. Pinguet, F. Bressolle, I. Solassol, 2006, Journal of pharmaceutical and biomedical analysis.

Liquid chromatography-electrospray mass spectrometry determination of free and total concentrations of ropivacaine in human plasma.

F. Bressolle, C. Dadure, D. Hillaire‐buys, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

High-performance liquid chromatographic determination of granisetron in human plasma.

F. Pinguet, C. Astre, F. Bressolle, 1996, Journal of chromatography. B, Biomedical applications.

High-performance liquid chromatographic assay for minocycline in human plasma and parotid saliva.

F. Bressolle, M. Audran, G. Bougard, 2000, Journal of chromatography. B, Biomedical sciences and applications.

Inter- and intra-individual variability in transdermal fentanyl absorption in cancer pain patients.

S. Culine, F. Pinguet, C. Astre, 2005, Oncology reports.

Stability indicating assay for dipyrone. Part II. Separation and quantitative determination of dipyrone and its degradation products by high-performance liquid chromatography.

F. Bressolle, H. Fabre, B. Mandrou, 1982, The Analyst.

Stability indicating assay for dipyrone. Part I. Separation and quantitative determination of dipyrone and its degradation products by thin-layer chromatography.

F. Bressolle, H. Fabre, B. Mandrou, 1982, The Analyst.

Influence of the schedule of exposure on the cytotoxic effect of melphalan on human 8226 and A2780 cells.

S. Culine, F. Pinguet, C. Astre, 1999, European journal of cancer.

In vitro modulation of doxorubicin and docetaxel antitumoral activity by methyl-beta-cyclodextrin.

F. Pinguet, F. Bressolle, P. Grosse, 1998, European journal of cancer.

Phase II study of melphalan as a single-agent infused over a 24-hour period with individual adapted dosing in patients with recurrent epithelial ovarian cancer.

S. Culine, F. Pinguet, F. Bressolle, 2006, Oncology reports.

Bayesian Parameter Estimates of Nelfinavir and Its Active Metabolite, Hydroxy-tert-Butylamide, in Infants Perinatally Infected with Human Immunodeficiency Virus Type 1

C. Giaquinto, F. Bressolle, R. Gomeni, 2005, Antimicrobial Agents and Chemotherapy.

Pharmacokinetics of artesunate in the domestic pig.

F. Bressolle, V. Sinou, D. Parzy, 2008, The Journal of antimicrobial chemotherapy.

High-performance liquid chromatographic determination of tazobactam and piperacillin in human plasma and urine.

F. Bressolle, M. Audran, P. Grosse, 1996, Journal of chromatography. B, Biomedical applications.

High-performance liquid chromatographic determination of the conjugate metabolites of moxisylyte in human plasma and urine.

F. Bressolle, C. Marquer, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Determination of nalbuphine in human plasma by high-performance liquid chromatography with electrochemical detection. Application to a pharmacokinetic study.

F. Bressolle, M. Audran, J. Kinowski, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Population pharmacokinetics of melphalan, infused over a 24-hour period, in patients with advanced malignancies

Françoise Bressolle, S. Culine, F. Pinguet, 2004, Cancer Chemotherapy and Pharmacology.

Pharmacokinetics and pharmacodynamics of recombinant human erythropoietin in athletes. Blood sampling and doping control.

F. Bressolle, M. Audran, J. Chanal, 2003, British journal of clinical pharmacology.

Pharmacokinetics and haematological parameters of recombinant human erythropoietin after subcutaneous administrations in horses.

F. Bressolle, M. Audran, R. Gareau, 1996, Biopharmaceutics & drug disposition.

A quantitative liquid chromatography tandem mass spectrometry method for metabolomic analysis of Plasmodium falciparum lipid related metabolites.

H. Vial, F. Bressolle, Sébastien Besteiro, 2012, Analytica chimica acta.

Pharmacology of EAPB0203, a novel imidazo[1,2-a]quinoxaline derivative with anti-tumoral activity on melanoma.

F. Pinguet, F. Bressolle, J. Cooper, 2010, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

High-performance liquid chromatographic assay for melphalan in human plasma. Application to pharmacokinetic studies.

J. M. Joulia, F. Pinguet, C. Astre, 1996, Journal of chromatography. B, Biomedical applications.

Study of the Performances of Thin Layer Chromatography. IV—Optimization of Experimental Conditions

A. Siouffi, G. Guiochon, F. Bressolle, 1979 .

Pharmacokinetics and pharmacodynamics of irinotecan and its metabolites from plasma and saliva data in patients with metastatic digestive cancer receiving Folfiri regimen

F. Pinguet, M. Ychou, J. Duffour, 2006, Cancer Chemotherapy and Pharmacology.

Salivary and plasma pharmacokinetics of topotecan in patients with metastatic epithelial ovarian cancer.

S. Culine, F. Pinguet, C. Astre, 2001, European journal of cancer.

Intraperitoneal administration of novel doxorubicin loaded polymeric delivery systems against peritoneal carcinomatosis: experimental study in a murine model of ovarian cancer.

F. Pinguet, F. Bressolle, P. Colombo, 2011, Gynecologic oncology.

Validation of an inductively coupled plasma-mass spectrometry method to quantify tungsten in human plasma. Determination of percentage binding to plasma proteins.

F. Bressolle, P. Poucheret, S. Le Lamer-Déchamps, 2003, Clinica chimica acta; international journal of clinical chemistry.

Assay method for the carboxylic acid metabolite of clopidogrel in human plasma by gas chromatography-mass spectrometry.

F. Bressolle, J. Necciari, P. Lagorce, 1998, Journal of chromatography. B, Biomedical sciences and applications.

Pharmacokinetic properties and metabolism of a new potent antimalarial N-alkylamidine compound, M64, and its corresponding bioprecursors.

H. Vial, F. Bressolle, Florence Gattacceca, 2011, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

HPLC with UV or mass spectrometric detection for quantifying endogenous uracil and dihydrouracil in human plasma.

F. Pinguet, F. Bressolle, R. Švobaitė, 2008, Clinical chemistry.

Structural characterization of in vitro metabolites of the new anticancer agent EAPB0503 by liquid chromatography-tandem mass spectrometry.

F. Bressolle, C. Enjalbal, I. Solassol, 2014, Journal of pharmaceutical and biomedical analysis.

Quantification of antimalarial bisthiazolium compounds and their neutral bioprecursors in plasma by liquid chromatography-electrospray mass spectrometry.

H. Vial, F. Bressolle, O. Nicolas, 2005, Clinical Chemistry.

Prodrugs of bisthiazolium salts are orally potent antimalarials.

H. Vial, F. Bressolle, O. Nicolas, 2004, Proceedings of the National Academy of Sciences of the United States of America.

A limited-sampling strategy to estimate individual pharmacokinetic parameters of vinorelbine in elderly patients with advanced metastatic cancer

Françoise Bressolle, S. Culine, F. Pinguet, 2002, Anti-cancer drugs.

Effects of erythropoietin administration in training athletes and possible indirect detection in doping control.

F. Bressolle, S. Matecki, M. Audran, 1999, Medicine and science in sports and exercise.

Clinical Impact of Intensified 5-Fluorouracil-Based Chemotherapy Using a Prospective Pharmacokinetically-Guided Dosing Approach: Comparative Study in Elderly and Non-Elderly Patients with Metastatic Colorectal Cancer

F. Pinguet, M. Ychou, J. Duffour, 2010 .

Quantitation of ibogaine and 12-hydroxyibogamine in human plasma by liquid chromatography with fluorimetric detection.

F. Bressolle, V. Briedis, D. Margout, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Liquid Chromatography-Electrospray Mass Spectrometry Determination of Ibogaine and 12-Hydroxy-Ibogamine in Human Urine

F. Bressolle, H. Breton, J. Mathieu-Daudé, 2006 .

Liquid chromatography-electrospray mass spectrometry determination of ibogaine and noribogaine in human plasma and whole blood. Application to a poisoning involving Tabernanthe iboga root.

F. Bressolle, O. Mathieu, H. Breton, 2006, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

High-performance liquid chromatographic determination of vinorelbine in human plasma and blood: application to a pharmacokinetic study.

F. Pinguet, C. Astre, F. Bressolle, 2000, Journal of chromatography. B, Biomedical sciences and applications.

Circadian rhythm of 5-fluorouracil population pharmacokinetics in patients with metastatic colorectal cancer

J. M. Joulia, F. Pinguet, M. Ychou, 1999, Cancer Chemotherapy and Pharmacology.

Individual 5FU-dose adaptation schedule using bimonthly pharmacokinetically modulated LV5FU2 regimen: a feasibility study in patients with advanced colorectal cancer.

J. M. Joulia, F. Pinguet, M. Ychou, 1999, Anticancer Research.

Liquid Chromatography‐Electrospray Mass Spectrometry Determination of Imatinib and Its Main Metabolite, N‐Desmethyl‐Imatinib in Human Plasma

F. Pinguet, C. Astre, F. Bressolle, 2006 .

Blood and plasma pharmacokinetics of vinorelbine in elderly patients with advanced metastatic cancer

S. Culine, F. Pinguet, C. Astre, 2001, Cancer Chemotherapy and Pharmacology.

Pharmacokinetics of 5-fluorouracil (5-FUra) in patients with metastatic colorectal cancer receiving 5-FUra bolus plus continuous infusion with high dose folinic acid (LV5FU2).

J. M. Joulia, F. Pinguet, M. Ychou, 1997, Anticancer research.

Quantitation of Melphalan in Human Plasma by Liquid Chromatography and Solid Phase Extraction: Application to Pharmacokinetic Study

S. Culine, F. Pinguet, F. Bressolle, 2004 .

High-performance liquid chromatographic determination of cefepime in human plasma and in urine and dialysis fluid using a column-switching technique.

F. Bressolle, J. Lefrant, J. Kinowski, 2001, Journal of chromatography. B, Biomedical sciences and applications.

Assay method for the perfluorooctyl bromide (perflubron) in rat blood by gas chromatography-mass spectrometry.

F. Bressolle, M. Audran, M. Krafft, 1999, Journal of chromatography. B, Biomedical sciences and applications.