Joel Morris

发表

CellMiner: a web-based suite of genomic and pharmacologic tools to explore transcript and drug patterns in the NCI-60 cell line set.

K. Kohn, W. Reinhold, Y. Pommier, 2012, Cancer research.

Comprehensive characterization of the Published Kinase Inhibitor Set

John P. Overington, D. J. Price, N. Sepetov, 2016, Nature Biotechnology.

Stereospecific PARP Trapping by BMN 673 and Comparison with Olaparib and Rucaparib

Y. Pommier, Joel Morris, J. Doroshow, 2013, Molecular Cancer Therapeutics.

Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression.

A. Monks, Dmitriy Sonkin, Joel Morris, 2016, Journal of the National Cancer Institute.

The effect of intramural delivery of polymeric nanoparticles loaded with the antiproliferative 2-aminochromone U-86983 on neointimal hyperplasia development in balloon-injured porcine coronary arteries

R. Levy, Joel Morris, V. Labhasetwar, 1997 .

Bromodomain and hedgehog pathway targets in small cell lung cancer.

A. Monks, Joel Morris, B. Teicher, 2016, Cancer letters.

Short-acting 5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as orally-active calcium-sensing receptor antagonists.

Daniel P. Walker, A. Kalgutkar, Joel Morris, 2009, Bioorganic & medicinal chemistry letters.

Small cell lung carcinoma cell line screen of etoposide/carboplatin plus a third agent

Dmitriy Sonkin, L. Rubinstein, Joel Morris, 2017, Cancer medicine.

Contribution of Leukotriene B4 to Airway Inflammation and the Effect of Antagonists

Joel Morris, F. Sun, B. Taylor, 1991, Annals of the New York Academy of Sciences.

Novel Molecules That Antagonize Leukotriene B4 Binding to Neutrophils

Joel Morris, R. Gorman, D. Wishka, 1988, Annals of the New York Academy of Sciences.

Synthesis of novel antagonists of leukotriene B4

Joel Morris, D. Wishka, 1988 .

Synthesis and biological activity of a potent antiplatelet 7-aminofurochromone

Joel Morris, C. Benjamin, R. Gorman, 1994 .

A Cyclodehydration Route to 2-Aminochromones

Joel Morris, D. Wishka, Yue Fang, 1994 .

Abstract CN05-01: PARP inhibitors: Trapping of PARP and rational for combinations.

Y. Pommier, Joel Morris, J. Doroshow, 2013 .

The total synthesis of the polyether antibiotic X-206

Joel Morris, S. Bender, Davidr . Evans, 1988 .

Stereoselective Synthesis of Furo[2,3-c]pyridine Pyrimidine Thioethers, A New Class of Potent HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors

Joel Morris, W. Watt, D. Wishka, 1998 .

Reaction of Phosgeniminium Salts with Enolates Derived from Lewis Acid Complexes of 2'-Hydroxypropiophenones and Related beta-Diketones.

Joel Morris, D. Wishka, G. P. Luke, 1996, The Journal of organic chemistry.

A novel synthesis of 2-aminochromones via phosgeniminium salts

Joel Morris, D. Wishka, Yue Fang, 1992 .

Discovery and synthesis of novel 4-aminopyrrolopyrimidine Tie-2 kinase inhibitors for the treatment of solid tumors.

Tracey Clark, Matthew D. Wessel, R. D. Connell, 2013, Bioorganic & medicinal chemistry letters.

Identification of phenylisoxazolines as novel and viable antibacterial agents active against Gram-positive pathogens.

L. Wienkers, Joel Morris, W. Watt, 2003, Journal of medicinal chemistry.

TITANIUM AND BORON MEDIATED ALDOL REACTIONS OF BETA -HYDROXY KETONES

Joel Morris, G. P. Luke, 1995 .

Total synthesis of pretyrosine (arogenate)

Joel Morris, S. Danishefsky, L. Clizbe, 1981 .

A new synthesis of phosphasteroids employing the McCormack cycloaddition for construction of the D-ring

L. D. Quin, Joel Morris, C. Symmes, 1977 .

The development of β-selective glycosylation reactions with benzyl substituted 2-deoxy-1,4-dithio-D-erythro-pentofuranosides: enabling practical multi-gram syntheses of 4'-Thio-2'-deoxycytidine (T-dCyd) and 5-aza-4’-thio-2’-deoxycytidine (aza-T-dCyd) to support clinical development

Joel Morris, B. Teicher, D. Wishka, 2020, Nucleosides, nucleotides & nucleic acids.

NCI-60 Whole Exome Sequencing and Pharmacological CellMiner Analyses

P. Meltzer, K. Kohn, W. Reinhold, 2014, PloS one.

Design of selective, ATP-competitive inhibitors of Akt.

Tracey Clark, Matthew Marx, Blaise Lippa, 2010, Journal of medicinal chemistry.

Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression

A. Monks, Joel Morris, B. Teicher, 2015, Molecular Cancer Therapeutics.

Achieving selectivity between highly homologous tyrosine kinases: a novel selective erbB2 inhibitor.

A. Mathiowetz, L. Pustilnik, Joel Morris, 2003, Biochemical and biophysical research communications.

ATR inhibitors VE-821 and VX-970 sensitize cancer cells to topoisomerase i inhibitors by disabling DNA replication initiation and fork elongation responses.

Y. Pommier, R. Guha, Joel Morris, 2014, Cancer research.

Discovery and pharmacologic characterization of CP-724,714, a selective ErbB2 tyrosine kinase inhibitor.

R. D. Connell, L. Pustilnik, Joel Morris, 2007, Cancer research.

Rationale for Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Combination Therapy with Camptothecins or Temozolomide Based on PARP Trapping versus Catalytic Inhibition

James H. Doroshow, Yves Pommier, Shunichi Takeda, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Asymmetric Syntheses and Absolute Stereochemistry of 5,6-Dihydro-α-pyrones, A New Class of Potent HIV Protease Inhibitors

Joel Morris, W. Watt, K. Romines, 1997 .

Asymmetric Syntheses and Absolute Stereochemistry of 5,6‐Dihydro‐α‐pyrones, a New Class of Potent HIV Protease Inhibitors.

Joel Morris, W. Watt, K. Romines, 1997 .

Cancer Biology and Signal Transduction Stereospeci fi c PARP Trapping by BMN 673 and Comparison with Olaparib and Rucaparib

Y. Pommier, Joel Morris, J. Doroshow, 2014 .

Rationale for PARP inhibitors in combination therapy with camptothecins or temozolomide based on PARP trapping versus catalytic inhibition

Y. Pommier, Joel Morris, J. Doroshow, 2014 .

Synthesis and structure based optimization of novel Akt inhibitors.

Tracey Clark, Blaise Lippa, J. Pandit, 2008, Bioorganic & medicinal chemistry letters.

Discovery of novel isothiazole inhibitors of the TrkA kinase: structure-activity relationship, computer modeling, optimization, and identification of highly potent antagonists.

Matthew D. Wessel, Joel Morris, M. Wessel, 2006, Bioorganic & medicinal chemistry letters.

F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd

Joel Morris, B. Teicher, M. Kunkel, 2021, Molecular Cancer Therapeutics.

Characterization of acute biliary hyperplasia in Fisher 344 rats administered the indole-3-carbinol analog, NSC-743380.

John R. Hamre, Joel Morris, B. Fang, 2014, Toxicology and applied pharmacology.

Discovery tactics to mitigate toxicity risks due to reactive metabolite formation with 2-(2-hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3h)-one derivatives, potent calcium-sensing receptor antagonists and clinical candidate(s) for the treatment of osteoporosis.

Daniel P. Walker, J. Bauman, A. Kalgutkar, 2010, Chemical research in toxicology.

PDFlib PLOP: PDF Linearization, Optimization, Protection Page inserted by evaluation version

Joel Morris, A. Herman, B. Taylor, 2002 .

Substituent effects on the antibacterial activity of nitrogen-carbon-linked (azolylphenyl)oxazolidinones with expanded activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.

Joel Morris, D. Anderson, M. Genin, 2000, Journal of medicinal chemistry.

Antibody-Drug Conjugate Targets, Drugs and Linkers.

Joel Morris, B. Teicher, 2022, Current cancer drug targets.

Targeting delavirdine/atevirdine resistant HIV-1: identification of (alkylamino)piperidine-containing bis(heteroaryl)piperazines as broad spectrum HIV-1 reverse transcriptase inhibitors.

Joel Morris, D. B. Evans, S. Sharma, 1996, Journal of medicinal chemistry.

Reaction of Phosgeniminium Salts with Enolates Derived from Lewis Acid Complexes of 2′-Hydroxypropiophenones and Related β-Diketones.

Joel Morris, D. Wishka, G. P. Luke, 1996 .

Total synthesis of dl-tazettine and 6a-epipretazettine: a formal synthesis of dl-pretazettine. Some observations on the relationship of 6a-epipretazettine and tazettine

Joel Morris, S. Danishefsky, G. Mullen, 1982 .