D. J. Heard

发表

Inroads to Predict in Vivo Toxicology—An Introduction to the eTOX Project

M. Cases, F. Sanz, K. Briggs, 2012, International journal of molecular sciences.

Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion.

A. Zell, P. Couttet, D. Schübeler, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Both Arabidopsis TATA binding protein (TBP) isoforms are functionally identical in RNA polymerase II and III transcription in plant cells: evidence for gene‐specific changes in DNA binding specificity of TBP.

W. Filipowicz, D. J. Heard, T. Kiss, 1993, The EMBO journal.

Epigenomics – Impact for Drug Safety Sciences

P. Couttet, D. J. Heard, O. Grenet, 2012 .

An upstream U-snRNA gene-like promoter is required for transcription of the Arabidopsis thaliana 7SL RNA gene.

W. Filipowicz, D. J. Heard, K. Palme, 1995, Nucleic acids research.

GCG Database Searching

David J. Heard, D. J. Heard, 2003 .

hTAF(II)68, a novel RNA/ssDNA‐binding protein with homology to the pro‐oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II.

P. Chambon, D. J. Heard, L. Tora, 1996, The EMBO journal.

Investigative safety science as a competitive advantage for Pharma

David J Heard, Michael Merz, Pierre Moulin, 2012, Expert opinion on drug metabolism & toxicology.

Human ERRgamma, a third member of the estrogen receptor-related receptor (ERR) subfamily of orphan nuclear receptors: tissue-specific isoforms are expressed during development and in the adult.

D. J. Heard, H. Vissing, P. L. Nørby, 2000, Molecular endocrinology.

SUG1, a Putative Transcriptional Mediator and Subunit of the PA700 Proteasome Regulatory Complex, Is a DNA Helicase*

P. Chambon, D. J. Heard, J. Egly, 1997, The Journal of Biological Chemistry.

Computational methods for early predictive safety assessment from biological and chemical data

Meir Glick, Florian Nigsch, Ben Cornett, 2011, Expert opinion on drug metabolism & toxicology.

The Putative Cofactor TIF1α Is a Protein Kinase That Is Hyperphosphorylated upon Interaction with Liganded Nuclear Receptors*

P. Chambon, R. Losson, D. J. Heard, 1998, The Journal of Biological Chemistry.

Toxicology ontology perspectives.

Imran Shah, Janna Hastings, Olga Tcheremenskaia, 2012, ALTEX.