H. Ding

发表

Genome-wide DNA methylation analysis reveals novel epigenetic changes in chronic lymphocytic leukemia

Gerald L. Arthur, Dong Xu, Jimei Liu, 2012, Epigenetics.

H. Ding, D. Fisher, 1998, Critical reviews in oncogenesis.

Antibiotic drug tigecycline reduces neuroblastoma cells proliferation by inhibiting Akt activation in vitro and in vivo

H. Ding, H. Cui, Xi Zhong, 2016, Tumor Biology.

Interleukin Enhancer-Binding Factor 3 Promotes Breast Tumor Progression by Regulating Sustained Urokinase-Type Plasminogen Activator Expression

Shuang Huang, H. Ding, Yiyu Lu, 2012, Oncogene.

Internal Ribosome Entry Site-Based Bicistronic In Situ Reporter Assays for Discovery of Transcription-Targeted Lead Compounds.

Xiaoguang Chen, H. Ding, Shi-Yong Sun, 2015, Chemistry & biology.

Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression

H. Ding, Mallikarjun Patil, Z. Dong, 2013, Cell cycle.

Bif-1 Interacts with Prohibitin-2 to Regulate Mitochondrial Inner Membrane during Cell Stress and Apoptosis.

H. Ding, Xiao-Ming Yin, R. Rafikov, 2019, Journal of the American Society of Nephrology : JASN.

Loss of negative feedback control of nuclear factor-kappaB2 activity in lymphocytes leads to fatal lung inflammation.

H. Ding, H. Cui, Zhe Wang, 2010, The American journal of pathology.

Cardiovascular , Pulmonary and Renal Pathology Loss of Negative Feedback Control of Nuclear Factor-B 2 Activity in Lymphocytes Leads to Fatal Lung Inflammation

H. Ding, H. Cui, Zhe Wang, 2010 .

H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growth

Huidong Shi, H. Ding, M. Grinstaff, 2022, Oncogene.

Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction

Shuang Huang, H. Ding, Xiao-Ming Yin, 2016, Autophagy.

Triple negative breast cancer development can be selectively suppressed by sustaining an elevated level of cellular cyclic AMP through simultaneously blocking its efflux and decomposition

Shuang Huang, H. Ding, S. Su, 2016, Oncotarget.

Constitutive Production of NF-κB2 p52 Is Not Tumorigenic but Predisposes Mice to Inflammatory Autoimmune Disease by Repressing Bim Expression*

H. Ding, Zhe Wang, Baochun Zhang, 2008, Journal of Biological Chemistry.

Stimulation of RNA polymerase II elongation by chromosomal protein HMG-14.

H. Ding, U. Hansen, M. Bustin, 1994, Science.

Linking of N-Myc to Death Receptor Machinery in Neuroblastoma Cells*

H. Ding, H. Cui, Tai Li, 2005, Journal of Biological Chemistry.

The CPLANE protein Intu protects kidneys from ischemia-reperfusion injury by targeting STAT1 for degradation

Shuang Huang, H. Ding, Guangyu Wu, 2018, Nature Communications.

NF-κB2 Is Required for the Control of Autoimmunity by Regulating the Development of Medullary Thymic Epithelial Cells*

H. Ding, P. Peterson, Zhe Wang, 2006, Journal of Biological Chemistry.

NF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis.

H. Ding, Zhe Wang, E. Tsitsikov, 2007, Blood.

A Negative Regulatory Role for RKIP in Breast Cancer Immune Response

R. Trumbly, H. Ding, K. Yeung, 2022, Cancers.

MYCN and Metabolic Reprogramming in Neuroblastoma

H. Ding, M. Bansal, Anamika Gupta, 2022, Cancers.

NF- (cid:1) B2 mutation targets TRAF1 to induce lymphomagenesis

H. Ding, Zhe Wang, E. Tsitsikov, 2007 .

Na/K-ATPase Mimetic pNaKtide Peptide Inhibits the Growth of Human Cancer Cells*

H. Ding, H. Cui, Jiang Tian, 2011, The Journal of Biological Chemistry.

PRMT1 promotes neuroblastoma cell survival through ATF5. Oncogenesis,

H. Ding, J. Hansen, Chao Wu, 2020 .

Phox2B correlates with MYCN and is a prognostic marker for neuroblastoma development.

Q. Xia, H. Ding, H. Cui, 2015, Oncology letters.

Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation

H. Ding, Ella L. Kim, H. Cui, 2013, Oncogene.

Leflunomide Reduces Proliferation and Induces Apoptosis in Neuroblastoma Cells In Vitro and In Vivo

Z. Xiang, H. Ding, H. Cui, 2013, PloS one.

in renal tubular cells mTOR contributes to ER stress and associated apoptosis

Shuang Huang, H. Ding, Z. Dong, 2016 .

mTOR contributes to ER stress and associated apoptosis in renal tubular cells.

Shuang Huang, H. Ding, Z. Dong, 2015, American journal of physiology. Renal physiology.

G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes

Huidong Shi, H. Ding, M. Grinstaff, 2022, Journal for ImmunoTherapy of Cancer.

p53 mediates DNA damaging drug-induced apoptosis through a caspase-9-dependent pathway in SH-SY5Y neuroblastoma cells.

H. Ding, H. Cui, A. Schroering, 2002, Molecular cancer therapeutics.

BMP4 and Neuregulin regulate the direction of mouse neural crest cell differentiation

H. Ding, H. Cui, Wanhong Liu, 2019, Experimental and therapeutic medicine.

A novel Lozenge gene in silkworm, Bombyx mori regulates the melanization response of hemolymph.

H. Ding, H. Cui, Juan Tan, 2015, Developmental and comparative immunology.

Bcl2 Regulation by the Melanocyte Master Regulator Mitf Modulates Lineage Survival and Melanoma Cell Viability

Sridhar Ramaswamy, Todd R. Golub, David E. Fisher, 2002, Cell.

ATF3 promotes erastin-induced ferroptosis by suppressing system Xc–

T. Du, H. Ding, Junran Zhang, 2019, Cell Death & Differentiation.

Glycine decarboxylase is a transcriptional target of MYCN required for neuroblastoma cell proliferation and tumorigenicity

H. Ding, Bingwei Ye, Jan van Riggelen, 2019, Oncogene.

Cyclin-dependent kinase 2 is an ideal target for ovary tumors with elevated cyclin E1 expression

Shuang Huang, H. Ding, Yiyu Lu, 2015, Oncotarget.

PRMT1 promotes neuroblastoma cell survival through ATF5

H. Ding, J. Hansen, Chao Wu, 2020, Oncogenesis.

The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation.

Yunhong Zha, Erhu Zhao, Shuang Huang, 2013, Cell metabolism.

Alleviation of histone H1-mediated transcriptional repression and chromatin compaction by the acidic activation region in chromosomal protein HMG-14

H. Ding, U. Hansen, M. Bustin, 1997, Molecular and cellular biology.

Loss of ATF3 Promotes Akt Activation and Prostate Cancer Development in a Pten Knockout Mouse Model

Tsonwin Hai, H. Ding, Ziyan Wang, 2014, Oncogene.

Loss of ATF3 Promotes Hormone-induced Prostate Carcinogenesis and the Emergence of CK5+CK8+ Epithelial Cells

Tsonwin Hai, H. Ding, Ziyan Wang, 2015, Oncogene.

Induction of apoptosis in cancer: new therapeutic opportunities

H. Ding, D. Fisher, 2002, Annals of medicine.

HOXC9 links cell-cycle exit and neuronal differentiation and is a prognostic marker in neuroblastoma.

B. McCarthy, H. Ding, H. Cui, 2011, Cancer research.

Tumor and Stem Cell Biology HOXC 9 Links Cell-Cycle Exit and Neuronal Differentiation and Is a Prognostic Marker in Neuroblastoma

B. McCarthy, H. Ding, H. Cui, 2011 .

Essential Role for Caspase-8 in Transcription-independent Apoptosis Triggered by p53*

J. Blenis, Junying Yuan, H. Ding, 2000, The Journal of Biological Chemistry.

MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development.

H. Ding, H. Cui, W. Maltese, 2009, The American journal of pathology.

DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma

H. Ding, R. Versteeg, J. Koster, 2021, bioRxiv.

Therapeutic targeting of both dihydroorotate dehydrogenase and nucleoside transport in MYCN-amplified neuroblastoma

H. Ding, Z. Dong, Chunhong Yan, 2021, Cell Death & Disease.

Metabolic reprogramming by MYCN confers dependence on the serine-glycine-one-carbon biosynthetic pathway.

O. Fiehn, Jeong-Hyeon Choi, H. Ding, 2019, Cancer research.

MEIS2 is essential for neuroblastoma cell survival and proliferation by transcriptional control of M-phase progression

Jeong-Hyeon Choi, H. Ding, S. Huang, 2014, Cell Death and Disease.

HOXC9 directly regulates distinct sets of genes to coordinate diverse cellular processes during neuronal differentiation

Shuang Huang, Huidong Shi, Jeong-Hyeon Choi, 2013, BMC Genomics.

Award Number: W81XWH-12-1-0613 TITLE: HOXC9-Induced Differentiation in Neuroblastoma Development PRINCIPAL INVESTIGATOR:

H. Ding, 2013 .

Functional Dissection of HOXD Cluster Genes in Regulation of Neuroblastoma Cell Proliferation and Differentiation

Yunhong Zha, Shuang Huang, Liqun Yang, 2012, PloS one.

Histone demethylase KDM6B has an anti-tumorigenic function in neuroblastoma by promoting differentiation

H. Ding, H. Cui, Z. Dong, 2019, Oncogenesis.

ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction

H. Ding, Junran Zhang, Chunhong Yan, 2021, Cell reports.

COP1 and GSK3β cooperate to promote c-Jun degradation and inhibit breast cancer cell tumorigenesis.

Jiahuai Han, Shuang Huang, H. Ding, 2013, Neoplasia.

Signaling by p38 MAPK Stimulates Nuclear Localization of the Microprocessor Component p68 for Processing of Selected Primary MicroRNAs

Shuang Huang, H. Ding, S. Su, 2013, Science Signaling.

Cyclin E1 is a common target of BMI1 and MYCN and a prognostic marker for neuroblastoma progression

Shuang Huang, H. Ding, H. Cui, 2011, Oncogene.

Bmi-1 Regulates the Differentiation and Clonogenic Self-renewal of I-type Neuroblastoma Cells in a Concentration-dependent Manner*

H. Ding, H. Cui, Jun Ma, 2006, Journal of Biological Chemistry.

ATF3 Deficiency Promotes Genome Instability and Spontaneous Tumorigenesis in Mice

Tsonwin Hai, H. Ding, Bilian Jin, 2017, Oncogene.

The Stress-responsive Gene ATF3 Regulates the Histone Acetyltransferase Tip60

H. Ding, Yi Tang, Junran Zhang, 2015, Nature Communications.

KDM4C and ATF4 Cooperate in Transcriptional Control of Amino Acid Metabolism.

Shuang Huang, Jeong-Hyeon Choi, H. Ding, 2016, Cell reports.

KDM 4 C and ATF 4 Coopera te in Transcriptional Control of Amino Acid Metabolism Graphical

Shuang Huang, Jeong-Hyeon Choi, H. Ding, 2022 .

Bmi-1 is essential for the tumorigenicity of neuroblastoma cells.

Hongjuan Cui, Jun Ma, Tai Li, 2007, The American journal of pathology.

Homeobox C9 suppresses Beclin1-mediated autophagy in glioblastoma by directly inhibiting the transcription of death-associated protein kinase 1.

H. Ding, H. Cui, Wen Liu, 2016, Neuro-oncology.

SHOX2 is a direct miR-375 target and a novel epithelial-to-mesenchymal transition inducer in breast cancer cells.

Shuang Huang, Huidong Shi, H. Ding, 2014, Neoplasia.

Epithelial-Mesenchymal Transition of Ovarian Cancer Cells Is Sustained by Rac1 through Simultaneous Activation of MEK1/2 and Src Signaling Pathways

Shuang Huang, H. Ding, S. Su, 2016, Oncogene.

Transcriptional Profiling Reveals a Common Metabolic Program in High-Risk Human Neuroblastoma and Mouse Neuroblastoma Sphere-Forming Cells.

Shuang Huang, Jeong-Hyeon Choi, H. Ding, 2016, Cell reports.

Yuan et al. DNA methylation in AKI

Lirong Pei, Shuang Huang, Huidong Shi, 2018 .

DNA methylation protects against cisplatin-induced kidney injury by regulating specific genes including interferon regulatory factor 8.

Lirong Pei, Shuang Huang, Huidong Shi, 2018 .

p53, Caspase 8, and Regulation of Apoptosis After Ionizing Radiation

H. Ding, D. Fisher, 2001, Journal of pediatric hematology/oncology.

NF-κB2 mutation targets TRAF1 to induce lymphomagenesis

H. Ding, Zhe Wang, E. Tsitsikov, 2007 .

p53/microRNA-214/ULK1 axis impairs renal tubular autophagy in diabetic kidney disease.

H. Ding, Z. Dong, C. Mei, 2020, The Journal of clinical investigation.

1National Cancer Institute, NIH. Research Associates and Howard Temin Award CA-78534 from Supported in part by a grant from the Ohio Cancer Cells 1 a Caspase-9-dependent Pathway in SH-SY5Y Neuroblastoma p53 Mediates DNA Damaging Drug-induced Apoptosis through

H. Ding, H. Cui, A. Schroering, 2013 .

p 53 Mediates DNA Damaging Drug-induced Apoptosis through a Caspase-9-dependent Pathway in SH-SY 5 Y Neuroblastoma Cells 1

H. Ding, H. Cui, A. Schroering, 2002 .

Transcriptional Regulation of Stem Cell and Cancer Stem Cell Metabolism

H. Ding, Bingwei Ye, A. Alptekin, 2017, Current Stem Cell Reports.

NF-κB2 p100 is a pro-apoptotic protein with anti-oncogenic function

William Arbuthnot Sir Lane, H. Ding, D. Fisher, 2002, Nature Cell Biology.

Competitive ubiquitination activates the tumor suppressor p53

T. Du, H. Ding, Junran Zhang, 2019, Cell Death & Differentiation.

The Stress-responsive Gene ATF3 Mediates Dichotomous UV Responses by Regulating the Tip60 and p53 Proteins*

H. Ding, Qi-En Wang, Junran Zhang, 2016, The Journal of Biological Chemistry.

Oncogene-dependent Regulation of Caspase Activation by p53 Protein in a Cell-free System*

H. Ding, D. Fisher, S. Rowan, 1998, The Journal of Biological Chemistry.

Nestin expression defines both glial and neuronal progenitors in postnatal sympathetic ganglia

H. Ding, H. Cui, W. Gunning, 2008, The Journal of comparative neurology.

Genome-wide analysis of HOXC9-induced neuronal differentiation of neuroblastoma cells

Jeong-Hyeon Choi, H. Ding, E. Kitamura, 2014, Genomics data.

GATA3 regulation of human neuroblastoma stem cell activity

H. Ding, Huilin Shi, 2009 .

HOXC8-Dependent Cadherin 11 Expression Facilitates Breast Cancer Cell Migration through Trio and Rac.

Shuang Huang, H. Ding, S. Su, 2011, Genes & cancer.

The CPLANE protein Intu protects kidneys from ischemia-reperfusion injury by targeting STAT1 for degradation

Shuang Huang, H. Ding, Guangyu Wu, 2018, Nature Communications.

Tubular cell senescence promotes maladaptive kidney repair and chronic kidney disease after cisplatin nephrotoxicity

H. Ding, Z. Dong, M. Livingston, 2023, JCI insight.

NF-κB2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors

M. Elsalanty, B. McCarthy, H. Ding, 2012, BMC Cancer.

NF-κB2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors

M. Elsalanty, B. McCarthy, H. Ding, 2012, BMC Cancer.

NF-kappa B2 p100 is a pro-apoptotic protein with anti-oncogenic function.

William Arbuthnot Sir Lane, H. Ding, D. Fisher, 2002, Nature cell biology.

Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma

H. Ding, S. Sudarshan, Kebin Liu, 2023, Cancer Research.

Nek1 interacts with Ku80 to assist chromatin loading of replication factors and S-phase progression

H. Ding, Mallikarjun Patil, Z. Dong, 2013, Cell cycle.

ATF3 Deficiency Promotes Genome Instability and Spontaneous Tumorigenesis in Mice

Tsonwin Hai, H. Ding, Bilian Jin, 2017, Oncogene.