P. Moss

P. Moss, S. Mackinnon, K. Peggs, 2003, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

Clonality in Healthy Elderly Individuals CD8 T Cell Repertoire Toward Greater Cytomegalovirus Seropositivity Drives the

P. Moss, J. Ainsworth, N. Khan, 2002 .

Developments in the treatment of post-transplant viral disease.

P. Moss, 2001, Best practice & research. Clinical haematology.

HLA class I-minor histocompatibility antigen tetramers select cytotoxic T cells with high avidity to the natural ligand.

P. Moss, T. Mutis, G. Gillespie, 2000, The hematology journal : the official journal of the European Haematology Association.

Primary care management of early stage chronic lymphocytic leukaemia is safe and effective.

P. Moss, P. Hazlewood, G. Pratt, 2015, QJM : monthly journal of the Association of Physicians.

Hypovitaminosis-D and EBV: no interdependence between two MS risk factors in a healthy young UK autumn cohort

P. Moss, G. Giovannoni, J. Kuhle, 2014, Multiple sclerosis.

CD4+CD28- T cell expansion in granulomatosis with polyangiitis (Wegener's) is driven by latent cytomegalovirus infection and is associated with an increased risk of infection and mortality.

P. Moss, C. Savage, I. Bajema, 2011, Arthritis and rheumatism.

Cytomegalovirus infection is a risk factor for venous thromboembolism in ANCA-associated vasculitis

P. Moss, D. Bunch, L. Harper, 2022, Arthritis Research & Therapy.

Subclinical Reactivation of Cytomegalovirus Drives CD4+CD28null T-Cell Expansion and Impaired Immune Response to Pneumococcal Vaccination in Antineutrophil Cytoplasmic Antibody–Associated Vasculitis

P. Moss, S. Faustini, C. Ferro, 2018, The Journal of infectious diseases.

Robust antibody responses in 70–80-year-olds 3 weeks after the first or second doses of Pfizer/BioNTech COVID-19 vaccine, United Kingdom, January to February 2021

P. Moss, H. Whitaker, S. Ladhani, 2021, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

Adenovirus infections following allogeneic stem cell transplantation: incidence and outcome in relation to graft manipulation, immunosuppression, and immune recovery.

C. Fegan, P. Moss, V. Mautner, 2002, Blood.

Defective monocyte enzymatic function and an inhibitory immune phenotype in HIV-exposed uninfected African infants in the era of highly active anti-retroviral therapy

P. Moss, R. Heyderman, E. Nastouli, 2021, medRxiv.

Asymptomatic Primary Infection with Epstein-Barr Virus: Observations on Young Adult Cases

P. Borrow, P. Moss, A. Rickinson, 2017, Journal of Virology.

The emerging role of cytomegalovirus in driving immune senescence: a novel therapeutic opportunity for improving health in the elderly.

P. Moss, 2010, Current opinion in immunology.

Apoptotic resistance to ionizing radiation in pediatric B-precursor acute lymphoblastic leukemia frequently involves increased NF-kappaB survival pathway signaling.

T. Stankovic, P. Moss, A. Taylor, 2004, Blood.

A phase I trial of the PARP inhibitor olaparib in patients with relapsed or refractory Chronic Lymphocytic Leukaemia, T-Prolymphocytic Leukaemia or Mantle Cell Lymphoma

A. Pettitt, M. Dyer, T. Stankovic, 2018 .

Mutation status of the residual ATM allele is an important determinant of the cellular response to chemotherapy and survival in patients with chronic lymphocytic leukemia containing an 11q deletion.

R. Siebert, M. Dyer, T. Stankovic, 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

University of Spontaneous CD4(+) and CD8(+) T-cell responses directed against cancer testis antigens are present in the peripheral blood of testicular cancer patients

P. Moss, P. Hutton, E. Porfiri, 2017 .

Cytomegalovirus infection is associated with an increase in systolic blood pressure in older individuals

Stuart J. Ritchie, I. Deary, J. Starr, 2016, QJM : monthly journal of the Association of Physicians.

Monocyte-Derived Dendritic Cells Receptor and Its Ligand in Human Differential Regulation of Vitamin

P. Moss, A. Eliopoulos, Evans, 2003 .

Research Ageing is associated with a decline in peripheral blood CD56 bright NK cells

P. Moss, N. Khan, L. Nayak, 2006 .

Poor functional antibody responses are present in nearly all patients with chronic lymphocytic leukaemia, irrespective of total IgG concentration, and are associated with increased risk of infection

M. Drayson, P. Moss, P. Hazlewood, 2015, British journal of haematology.

Donor KIR Genotype Does Not Affect VZV Reactivation after Allogeneic Haematopoietic Stem Cell Transplantation.

C. Craddock, P. Moss, S. Nagra, 2005 .

Variations in ATM protein expression during normal lymphoid differentiation and among B-cell-derived neoplasias.

T. Stankovic, G. Stewart, C. Fegan, 2003, The American journal of pathology.

of The role of allogeneic stem cell transplantation in the management of acute myeloid leukaemia

C. Craddock, P. Moss, R. Malladi, 2019 .

Impact of Cytomegalovirus on Long-term Mortality and Cancer Risk After Organ Transplantation

P. Moss, J. Neuberger, P. Johnson, 2015, Transplantation.

ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells.

T. Stankovic, G. Stewart, P. Moss, 2016, Blood.

Analysis of ZAP70 expression in adult acute lymphoblastic leukaemia by real time quantitative PCR

P. Moss, M. Griffiths, A. Bell, 2012, Molecular Cytogenetics.

Neoplastic plasma cells generate an inflammatory environment within bone marrow and markedly alter the distribution of T cells between lymphoid compartments

P. Moss, O. Goodyear, S. Basu, 2017, Oncotarget.

transplantation cytomegalovirus reactivation following T-cell replete stem cell genotype has a major influence on the rate of KIR Donor

C. Craddock, C. Fegan, P. Moss, 2012 .

Clostn'ch'um perfringens Enterotoxl- is a Superantigen Reactive with Human T Cell Receptors V136.9 and V1322

P. Moss, P. Bowness, H. Tranter, 1992 .

Differential regulation of vitamin D receptor and its ligand in human dendritic cells: A paracrine mechanism for regulation of antigen presentation

P. Moss, M. Hewison, R. Chakraverty, 2003 .

NK cells produce high levels of IL‐10 early after allogeneic stem cell transplantation and suppress development of acute GVHD

C. Craddock, P. Moss, S. Nagra, 2017, European journal of immunology.

ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele

M. Dyer, T. Stankovic, C. Fegan, 2012, Haematologica.

damage response and unrepaired chromosome damage leukemia occurs in pregerminal center cells and results in defective deficient B-cell chronic lymphocytic - Ataxia telangiectasia mutated

T. Stankovic, G. Stewart, P. Byrd, 2013 .

CD8+ T-cell immunity against cancer-testis antigens develops following allogeneic stem cell transplantation and reveals a potential mechanism for the graft-versus-leukemia effect

C. Craddock, P. Moss, K. Piper, 2010, Haematologica.

Extended interval BNT162b2 vaccination enhances peak antibody generation in older people

P. Moss, R. Bruton, K. Brown, 2021, medRxiv.

Cytomegalovirus‐Associated CD4+CD28null Cells in NKG2D‐Dependent Glomerular Endothelial Injury and Kidney Allograft Dysfunction

P. Moss, R. Borrows, L. Harper, 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

Characterization of CMV-specific CD4+ T-cell reconstitution following stem cell transplantation through the use of HLA Class II-peptide tetramers identifies patients at high risk of recurrent CMV reactivation

C. Craddock, P. Moss, A. Pachnio, 2015, Haematologica.

Mixed chimerism established by hematopoietic stem cell transplantation is maintained by host and donor T regulatory cells.

C. Craddock, P. Moss, S. Nagra, 2019, Blood advances.

Chapter 28 History and d evelopment of m olecular b iology

P. Moss, 2010 .

CMV infection of human sinusoidal endothelium regulates hepatic T cell recruitment and activation.

P. Badenhorst, P. Moss, C. Weston, 2015, Journal of hepatology.

Direct observations of the kinetics of migrating T cells suggest active retention by endothelial cells with continual bidirectional migration

P. Moss, C. Buckley, G. Nash, 2008, Journal of leukocyte biology.

CXCL10-CXCR3 interactions play an important role in the pathogenesis of acute graft-versus-host disease in the skin following allogeneic stem-cell transplantation.

C. Craddock, P. Moss, K. Piper, 2007, Blood.

Cytomegalovirus infection does not impact on survival or time to first treatment in patients with chronic lymphocytic leukemia

J. Cerhan, T. Shanafelt, S. Slager, 2016, American journal of hematology.

Recruitment mechanisms of primary and malignant B cells to the human liver

P. Moss, C. Weston, G. Reynolds, 2012, Hepatology.

Health state utilities for chronic lymphocytic leukemia: importance of prolonging progression-free survival

P. Moss, A. Lloyd, K. Samanta, 2015, Leukemia & lymphoma.

Cytomegalovirus seropositivity is independently associated with cardiovascular disease in non-dialysis dependent chronic kidney disease.

P. Moss, P. Cockwell, C. Ferro, 2019, QJM : monthly journal of the Association of Physicians.

Origin and subset distribution of peripheral blood dendritic cells in patients with chronic graft-versus-host disease1

C. Craddock, P. Moss, P. Mahendra, 2003, Transplantation.

University of Birmingham NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma

T. Stankovic, P. Moss, Z. Rudzki, 2017 .

Valaciclovir to prevent Cytomegalovirus mediated adverse modulation of the immune system in ANCA-associated vasculitis (CANVAS): study protocol for a randomised controlled trial

P. Moss, P. Nightingale, L. Harper, 2016, Trials.

Study Protocol: Understanding SARS-Cov-2 infection, immunity and its duration in care home residents and staff in England (VIVALDI)

J. Farrar, A. Copas, P. Moss, 2021, Wellcome open research.

immunosuppression, and immune recovery incidence and outcome in relation to graft manipulation, Adenovirus infections following allogeneic stem cell transplantation:

C. Fegan, P. Moss, V. Mautner, 2013 .

Adenovirus Infections in Stem Cell Transplant Recipients: Recent Developments in Understanding of Pathogenesis, Diagnosis and Management

P. Moss, V. Mautner, D. Milligan, 2004, Leukemia & lymphoma.

Memory B-cell reconstitution following allogeneic hematopoietic stem cell transplantation is an EBV-associated transformation event.

C. Craddock, P. Moss, S. Nagra, 2015, Blood.

Greatly reduced risk of EBV reactivation in rituximab-experienced recipients of alemtuzumab-conditioned allogeneic HSCT

C. Craddock, P. Moss, S. Nagra, 2016, Bone Marrow Transplantation.

The role of allogeneic stem cell transplantation in the management of acute myeloid leukaemia: a triumph of hope and experience

C. Craddock, P. Moss, R. Malladi, 2019, British journal of haematology.

The UPTAKE study: a cross-sectional survey examining the insights and beliefs of the UK population on COVID-19 vaccine uptake and hesitancy

P. Moss, S. Basu, Aditi Kumar, 2021, BMJ Open.

Covid-19 infection in therapy-naive patients with B-cell chronic lymphocytic leukemia

P. Moss, G. Pratt, S. Paneesha, 2020, Leukemia Research.

Biology and management of relapsed acute myeloid leukaemia

C. Craddock, P. Moss, D. Grimwade, 2005, British journal of haematology.

Perturbation of the normal immune system in patients with CLL.

P. Moss, F. Forconi, 2015, Blood.

Direct visualization of cytomegalovirus-specific T-cell reconstitution after allogeneic stem cell transplantation.

C. Craddock, P. Moss, J. Ainsworth, 2001, Blood.

The cellular immunotherapy of viral infection

C. Craddock, P. Moss, M. Cobbold, 2003, Transfusion medicine.

Cytomegalovirus viral load within blood increases markedly in healthy people over the age of 70 years

P. Moss, M. Griffiths, G. Pratt, 2016, Immunity & Ageing.

Immunosenescence and Cytomegalovirus: where do we stand after a decade?

P. Griffiths, P. Moss, G. Pawelec, 2010, Immunity & Ageing.

Antibody responses after first and second Covid-19 vaccination in patients with chronic lymphocytic leukaemia

P. Moss, R. Bruton, S. Faustini, 2021, Blood Cancer Journal.

Herpesvirus-Specific CD8 T Cell Immunity in Old Age: Cytomegalovirus Impairs the Response to a Coresident EBV Infection1

P. Moss, R. Khanna, N. Khan, 2004, The Journal of Immunology.

High Expression of CD 95 a Congenitally Aged Immune System with Classical Ataxia Telangiectasia Patients Have and

P. Moss, A. Taylor, V. Srinivasan, 2012 .

Maternal effector T cells within decidua: The adaptive immune response to pregnancy?

P. Moss, M. Kilby, D. Lissauer, 2017, Placenta.

Immunodeficiency and immunotherapy in multiple myeloma

P. Moss, O. Goodyear, G. Pratt, 2007, British journal of haematology.

The polycomb group proteins, BMI-1 and EZH2, are tumour-associated antigens

P. Moss, G. Reynolds, D. Adams, 2006, British Journal of Cancer.

Spontaneous CD4+ and CD8+ T‐cell responses directed against cancer testis antigens are present in the peripheral blood of testicular cancer patients

P. Moss, P. Hutton, E. Porfiri, 2017, European journal of immunology.

Acyclovir Therapy Reduces the CD4+ T Cell Response against the Immunodominant pp65 Protein from Cytomegalovirus in Immune Competent Individuals

P. Moss, A. Pachnio, Jusnara Begum, 2015, PloS one.

InfectionMice with Latent Cytomegalovirus Development of Immune Senescence in Antiviral Therapy Can Reverse the

P. Moss, S. Lauder, A. Pachnio, 2014 .

Antiviral Therapy Can Reverse the Development of Immune Senescence in Elderly Mice with Latent Cytomegalovirus Infection

P. Moss, C. Sweet, S. Lauder, 2012, Journal of Virology.

Infection Elderly Mice with Latent Cytomegalovirus Development of Immune Senescence in Antiviral Therapy Can Reverse the

Clive, P. Moss, S. Lauder, 2012 .

The Cytomegalovirus-Specific CD4+ T-Cell Response Expands with Age and Markedly Alters the CD4+ T-Cell Repertoire

P. Moss, N. Khan, R. Bruton, 2007, Journal of Virology.

USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status.

T. Stankovic, G. Stewart, P. Moss, 2017, Blood.

USP 7 inhibition alters homologous recombination repair and targets CLL cells independent of ATM / p 53 functional status Running title : USP 7 INHIBITION TARGETS ATM AND P 53 DEFECTIVE CLL

Shankara, T. Stankovic, G. Stewart, 2017 .

lymphoid tumor cells in vitro and in vivo -deficient ATM The PARP inhibitor olaparib induces significant killing of

M. Dyer, T. Stankovic, P. Moss, 2012 .

The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.

M. Dyer, T. Stankovic, P. Moss, 2010, Blood.

A novel CDK inhibitor, CYC202 (R-roscovitine), overcomes the defect in p53-dependent apoptosis in B-CLL by down-regulation of genes involved in transcription regulation and survival.

David P Lane, T. Stankovic, C. Fegan, 2005, Blood.

Microarray analysis reveals that TP53- and ATM-mutant B-CLLs share a defect in activating proapoptotic responses after DNA damage but are distinguished by major differences in activating prosurvival responses.

T. Stankovic, G. Stewart, P. Byrd, 2004, Blood.

Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD / SCID mice

T. Stankovic, G. Stewart, P. Byrd, 2002 .

Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia

T. Stankovic, G. Stewart, P. Byrd, 1999, The Lancet.

Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL.

T. Stankovic, P. Moss, A. Taylor, 2019, Blood.

NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma

T. Stankovic, P. Moss, Z. Rudzki, 2016, Oncotarget.

T cell responses to d-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes

Paul Wordsworth, P. Moss, N. Willcox, 1999, Journal of Neuroimmunology.

Systematic study of human αβ T cell receptor V segments shows allelic variations resulting in a large number of distinct T cell receptor haplotypes

P. Moss, C. Julier, R. Harding, 1993 .

Variation in human T cell receptor Vβ and Jβ repertoire: analysis using anchor polymerase chain reaction

J. Bell, P. Moss, W. Rosenberg, 1992 .

Influenza Virus Lung Infection Protects from Respiratory Syncytial Virus–Induced Immunopathology

Gerhard Walzl, Paul Moss, P. Moss, 2000, The Journal of experimental medicine.

dendritic cells repertoire diversity following in vitro restimulation by antigen-pulsed specific CD8+ T-cell - Characterization of human cytomegalovirus peptide

P. Moss, S. Mackinnon, K. Peggs, 2013 .

CD117 (c-Kit) Is Expressed During CD8+ T Cell Priming and Stratifies Sensitivity to Apoptosis According to Strength of TCR Engagement

P. Moss, J. Zuo, G. Frumento, 2019, Front. Immunol..

Large clonal expansions of CD8+ T cells in acute infectious mononucleosis

J. Bell, A. McMichael, P. Moss, 1996, Nature Medicine.

Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia.

P. Vyas, C. Craddock, T. Stankovic, 2010, Blood.

Characterization of the human T cell receptor α‐chain repertoire and demonstration of a genetic influence on Vα usage

J. Bell, P. Moss, E. Zintzaras, 1993, European journal of immunology.

Checkpoint Inhibition in Hodgkin Lymphoma: Time to Check at Which Point to Use It

P. Moss, 2016 .

NK cells in pancreatic cancer demonstrate impaired cytotoxicity and a regulatory IL-10 phenotype

Rachel M. Brown, P. Moss, G. Middleton, 2020, Oncoimmunology.

The number of cytomegalovirus-specific CD4+ T cells is markedly expanded in patients with B-cell chronic lymphocytic leukemia and determines the total CD4+ T-cell repertoire.

C. Fegan, P. Moss, L. Billingham, 2010, Blood.

Vaccine effectiveness of the first dose of ChAdOx1 nCoV-19 and BNT162b2 against SARS-CoV-2 infection in residents of long-term care facilities in England (VIVALDI): a prospective cohort study

A. Copas, P. Moss, C. Fuller, 2021, The Lancet Infectious Diseases.

Human CD34+ hematopoietic progenitor cells hyperacetylate core histones in response to sodium butyrate, but not trichostatin A.

B. Turner, P. Moss, H. Travers, 2002, Experimental cell research.

CMV and Immunosenescence: from basics to clinics

V. Appay, P. Moss, G. Pawelec, 2012, Immunity & Ageing.

Genotypic analysis of two hypervariable human cytomegalovirus genes

P. Moss, T. Schulz, A. Davison, 2008, Journal of medical virology.

B cells immortalized by a mini-Epstein-Barr virus encoding a foreign antigen efficiently reactivate specific cytotoxic T cells.

P. Moss, B. Wollenberg, N. Khan, 2002, Blood.

Post-transplant T cell chimerism predicts graft versus host disease but not disease relapse in patients undergoing an alemtuzumab based reduced intensity conditioned allogeneic transplant.

C. Craddock, P. Moss, S. Nagra, 2013, Leukemia research.

CXCL 10-CXCR 3 interactions play an important role in the pathogenesis of acute graft-versus-host disease in the skin following allogeneic stem-cell transplantation

C. Craddock, P. Moss, K. Piper, 2007 .

Functional Heterogeneity and High Frequencies of Cytomegalovirus-Specific CD8+ T Lymphocytes in Healthy Seropositive Donors

J. Bell, V. Appay, P. Moss, 2000, Journal of Virology.

Virus-specific cytotoxic T lymphocytes differentially express cell-surface leukocyte immunoglobulin-like receptor-1, an inhibitory receptor for class I major histocompatibility complex molecules.

P. Moss, N. Khan, A. Rickinson, 2005, The Journal of infectious diseases.

Azacitidine augments expansion of regulatory T cells after allogeneic stem cell transplantation in patients with acute myeloid leukemia (AML).

P. Vyas, C. Craddock, P. Moss, 2012, Blood.

Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.

P. Moss, C. O'Callaghan, Ayman Antoun, 2010, Human immunology.

Cellular immunotherapy for viral infection after HSC transplantation

P. Moss, A. Rickinson, 2005, Nature Reviews Immunology.

CD8(+) T-cell immunity to cytomegalovirus.

P. Moss, N. Khan, 2004, Human immunology.

High frequency of cytomegalovirus-specific cytotoxic T-effector cells in HLA-A*0201-positive subjects during multiple viral coinfections.

D. Nixon, X. Jin, S. Bonhoeffer, 2000, The Journal of infectious diseases.

Decay Kinetics of Human Immunodeficiency Virus-Specific Effector Cytotoxic T Lymphocytes after Combination Antiretroviral Therapy

M. Nowak, D. Ho, Y. Cao, 1999, Journal of Virology.

Very early lineage-specific chimerism after reduced intensity stem cell transplantation is highly predictive of clinical outcome for patients with myeloid disease.

C. Craddock, P. Moss, S. Nagra, 2019, Leukemia research.

Systematic analysis of infectious disease outcomes by age shows lowest severity in school-age children

P. Moss, J. Glynn, 2020, Scientific Data.

Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition

P. van Endert, S. Tenzer, H. Schild, 2009, Proceedings of the National Academy of Sciences.

Safety and Efficacy of Antiviral Therapy for Prevention of Cytomegalovirus Reactivation in Immunocompetent Critically Ill Patients: A Randomized Clinical Trial

P. Moss, J. Bion, A. Owen, 2017, JAMA internal medicine.

A first-in-human phase 1 trial to evaluate the safety and immunogenicity of the candidate tuberculosis vaccine MVA85A-IMX313, administered to BCG-vaccinated adults

P. Moss, H. McShane, A. Lawrie, 2016, Vaccine.

A Phase I, Open-Label Trial, Evaluating the Safety and Immunogenicity of Candidate Tuberculosis Vaccines AERAS-402 and MVA85A, Administered by Prime-Boost Regime in BCG-Vaccinated Healthy Adults

P. Moss, B. Landry, H. McShane, 2015, PloS one.

Cytomegalovirus-Specific T Cells Restricted by HLA-Cw*0702 Increase Markedly with Age and Dominate the CD8+ T-Cell Repertoire in Older People

P. Moss, S. Riddell, Louise Hosie, 2017, Front. Immunol..

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA–peptide tetramers

C. Craddock, P. Moss, L. Billingham, 2005, The Journal of experimental medicine.

Peptide anchor residue glycosylation: effect on class I major histocompatibility complex binding and cytotoxic T lymphocyte recognition

R. Dwek, T. Elliott, A. McMichael, 1995, European journal of immunology.

Cytomegalovirus is associated with depression and anxiety in older adults

D. Carroll, P. Moss, N. Khan, 2008, Brain, Behavior, and Immunity.

Anticytomegalovirus antibody titres are not associated with caregiving burden in younger caregivers.

P. Moss, J. Lord, S. Gallagher, 2015, British journal of health psychology.

A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding

P. Moss, R. Malladi, M. Davey, 2017, Science Signaling.

Decidual T Cells Exhibit a Highly Differentiated Phenotype and Demonstrate Potential Fetal Specificity and a Strong Transcriptional Response to IFN

P. Moss, M. Kilby, A. Beggs, 2017, The Journal of Immunology.

PD-1 is imprinted on cytomegalovirus-specific CD4+ T cells and attenuates Th1 cytokine production whilst maintaining cytotoxicity

P. Moss, G. Pratt, J. Zuo, 2021, PLoS pathogens.

Cord Blood T Cells Retain Early Differentiation Phenotype Suitable for Immunotherapy After TCR Gene Transfer to Confer EBV Specificity

P. Moss, P. Lansdorp, S. Lee, 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

HIV patients on antiretroviral therapy have high frequencies of CD8 T cells specific for Immediate Early protein-1 of cytomegalovirus

P. Moss, N. Khan, P. Price, 2005, AIDS.

A rare complication of bone marrow aspiration and trephine biopsy: Staphylococcus aureus osteomyelitis and septicaemia

P. Moss, G. Pratt, Muhammad Khakwani, 2018, British journal of haematology.

Memory T Cells Constitute a Subset of the Human CD8+CD45RA+ Pool with Distinct Phenotypic and Migratory Characteristics1

P. Moss, D. Adams, M. Salmon, 2001, The Journal of Immunology.

Cytomegalovirus Seropositivity Is Associated with Increased Arterial Stiffness in Patients with Chronic Kidney Disease

P. Moss, J. Townend, R. Steeds, 2013, PloS one.

C. Cooper, P. Moss, J. Lord, 2012, Aging cell.

Serum Free Light Chain Levels Post Allogeneic Stem Cell Transplantation Are Associated With Improved Overall Survival In Patients With Acute Myeloid Leukemia

C. Craddock, P. Moss, R. Malladi, 2013 .

Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts

T. Stankovic, P. Moss, M. Griffiths, 2017, Oncotarget.

Differential pattern of CD4+ and CD8+ T-cell immunity to MAGE-A1/A2/A3 in patients with monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma.

P. Moss, K. Piper, O. Goodyear, 2008, Blood.

The CD4+ T-cell response to adenovirus is focused against conserved residues within the hexon protein.

P. Moss, V. Mautner, D. Onion, 2007, The Journal of general virology.

Adoptive cellular therapy for early cytomegalovirus infection after allogeneic stem-cell transplantation with virus-specific T-cell lines

P. Moss, S. Mackinnon, K. Peggs, 2003, The Lancet.

Differential Regulation of Vitamin D Receptor and Its Ligand in Human Monocyte-Derived Dendritic Cells1

Aristides G. Eliopoulos, Ronjon Chakraverty, P. Moss, 2003, The Journal of Immunology.

Allelic polymorphism of human T-cell receptor V alpha gene segments

J. Bell, P. Moss, R. Harding, 2004, Immunogenetics.

T Cell Recognition Patterns of Immunodominant Cytomegalovirus Antigens in Primary and Persistent Infection

P. Moss, N. Khan, R. Bruton, 2007, The Journal of Immunology.

Structural and energetic evidence for highly peptide-specific tumor antigen targeting via allo-MHC restriction

P. Moss, A. Rickinson, H. Stauss, 2011, Proceedings of the National Academy of Sciences.

CD4+ T cells specific for glycoprotein B from cytomegalovirus exhibit extreme conservation of T-cell receptor usage between different individuals.

P. Moss, R. Khanna, N. Khan, 2008, Blood.

TALEN-mediated genetic inactivation of the glucocorticoid receptor in cytomegalovirus-specific T cells.

P. Moss, S. Quezada, K. Peggs, 2015, Blood.

Identification of Cytomegalovirus-Specific Cytotoxic T Lymphocytes In Vitro Is Greatly Enhanced by the Use of Recombinant Virus Lacking the US2 to US11 Region or Modified Vaccinia Virus Ankara Expressing Individual Viral Genes

P. Moss, N. Khan, M. Cobbold, 2005, Journal of Virology.

Response to a Coresident EBV Infection Old Age: Cytomegalovirus Impairs the Herpesvirus-Specific CD8 T Cell Immunity in

P. Moss, R. Khanna, N. Khan, 2004 .

Impaired direct priming of CD8 T cells by donor-derived cytomegalovirus following kidney transplantation.

P. Moss, R. Borrows, A. Rahbar, 2013, Journal of the American Society of Nephrology : JASN.

‘From immunosenescence to immune modulation’: a re-appraisal of the role of cytomegalovirus as major regulator of human immune function

P. Moss, 2019, Medical Microbiology and Immunology.

‘From immunosenescence to immune modulation’: a re-appraisal of the role of cytomegalovirus as major regulator of human immune function

P. Moss, 2019, Medical Microbiology and Immunology.

Report from the second cytomegalovirus and immunosenescence workshop

S. J. Griffiths, D. Melzer, P. Klenerman, 2011, Immunity & Ageing.

DNA fusion vaccines induce epitope-specific cytotoxic CD8(+) T cells against human leukemia-associated minor histocompatibility antigens.

P. Moss, K. Piper, J. Rice, 2006, Cancer research.

antigen efficiently reactivate specific cytotoxic T cells Epstein-Barr virus encoding a foreign - B cells immortalized by a mini

P. Moss, B. Wollenberg, N. Khan, 2013 .

Cytomegalovirus‐seropositivity has a profound influence on the magnitude of major lymphoid subsets within healthy individuals

P. Moss, L. Nayak, A. McLarnon, 2009, Clinical and experimental immunology.

Chronic lymphocytic leukaemia cells drive the global CD4+ T cell repertoire towards a regulatory phenotype and leads to the accumulation of CD4+ forkhead box P3+ T cells

P. Moss, K. Piper, N. Khan, 2011, Clinical and experimental immunology.

Phenotypic and Migratory Characteristics Pool with Distinct + CD 45 RA + Human CD 8 Memory T Cells Constitute a Subset of the

P. Moss, M. Salmon, A. Rickinson, 2001 .

Phase I Trial Evaluating the Safety and Immunogenicity of Candidate TB Vaccine MVA85A, Delivered by Aerosol to Healthy M.tb-Infected Adults

F. Gleeson, P. Moss, H. McShane, 2021, Vaccines.

Persistent viral infection in humans can drive high frequency low‐affinity T‐cell expansions

P. Moss, N. Khan, M. Cobbold, 2010, Immunology.

The number of CD56dim NK cells in the graft has a major impact on risk of disease relapse following allo-HSCT.

C. Craddock, P. Moss, R. Malladi, 2017, Blood advances.

Dominant responses with conservation of T-cell receptor usage in the CD8+ T-cell recognition of a cancer testis antigen peptide presented through HLA-Cw7 in patients with multiple myeloma

P. Moss, O. Goodyear, G. Pratt, 2011, Cancer Immunology, Immunotherapy.

The Cellular Localization of Human Cytomegalovirus Glycoprotein Expression Greatly Influences the Frequency and Functional Phenotype of Specific CD4+ T Cell Responses

P. Moss, J. Zuo, Gordon B Ryan, 2015, The Journal of Immunology.

Elevated HbA1c levels and the accumulation of differentiated T cells in CMV+ individuals

J. Dowd, V. Burns, P. Moss, 2015, Diabetologia.

Azacitidine for the treatment of steroid-refractory chronic graft-versus-host disease: the results of the phase II AZTEC clinical trial

C. Craddock, P. Moss, S. Siddique, 2021, Bone Marrow Transplantation.

Clonal populations of CD4+ and CD8+ T cells in patients with multiple myeloma and paraproteinemia.

P. Moss, H. Reyburn, J. Bell, 1996, Blood.

Clonal populations of T-cells in patients with B-cell malignancies.

P. Moss, G. Gillespie, 1997, Leukemia & lymphoma.

myeloma and paraproteinemia Clonal populations of CD4+ and CD8+ T cells in patients with multiple

P. Moss, H. Reyburn, G. Gillespie, 2011 .

A phase I trial evaluating the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime – MVA85A boost in healthy UK adults

P. Moss, H. McShane, M. O’Shea, 2019, Vaccine.

CD4+CD28– T-cell expansions in ANCA-associated vasculitis and association with arterial stiffness: baseline data from a randomised controlled trial

P. Moss, L. Harper, M. Morgan, 2015, The Lancet.

homing phenotype within the human bone marrow Selective accumulation of virus-specific CD8+ T cells with unique

P. Moss, K. Piper, N. Khan, 2013 .

Selective accumulation of virus-specific CD8+ T cells with unique homing phenotype within the human bone marrow.

P. Moss, K. Piper, N. Khan, 2008, Blood.

Homeostatic Cytokines Drive Epigenetic Reprogramming of Activated T Cells into a “Naive-Memory” Phenotype

P. Moss, Z. Nagy, G. Anderson, 2020, iScience.

Long-Term Ibrutinib Therapy Reverses CD8+ T Cell Exhaustion in B Cell Chronic Lymphocytic Leukaemia

T. Stankovic, P. Moss, G. Pratt, 2019, Front. Immunol..

Seropositivity for CMV and IL-6 levels are associated with grip strength and muscle size in the elderly

I. Deary, M. Bastin, J. Starr, 2013, Immunity & Ageing.

Higher serological responses and increased vaccine effectiveness demonstrate the value of extended vaccine schedules in combatting COVID-19 in England

P. Moss, H. Whitaker, N. Andrews, 2021, medRxiv.

Study Protocol: Understanding SARS-Cov-2 infection, immunity and its duration in care home residents and staff in England (VIVALDI).

J. Farrar, A. Copas, P. Moss, 2020, Wellcome open research.

A multi‐centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T‐prolymphocytic leukaemia or mantle cell lymphoma

A. Pettitt, M. Dyer, T. Stankovic, 2018, British journal of haematology.

“The ancient and the new”: is there an interaction between cytomegalovirus and SARS-CoV-2 infection?

P. Moss, 2020, Immunity & Ageing.

Intercellular adhesion molecule-1 expression in endothelial cells is activated by cytomegalovirus immediate early proteins.

P. Moss, 1999, Transplantation.

Mimicry Not Replacement: Molecular Engineering Transforms the Outlook in Hemophilia A

Paul Moss, P. Moss, 2018 .

Cytomegalovirus drives Vδ2neg γδ T cell inflation in many healthy virus carriers with increasing age

P. Moss, N. Khan, S. Christmas, 2014, Clinical and experimental immunology.

Progesterone promotes maternal–fetal tolerance by reducing human maternal T‐cell polyfunctionality and inducing a specific cytokine profile

P. Moss, M. Kilby, S. Eldershaw, 2015, European journal of immunology.

Incidence of SARS-CoV-2 infection according to baseline antibody status in staff and residents of 100 long-term care facilities (VIVALDI): a prospective cohort study

A. Copas, P. Moss, C. Fuller, 2021, The Lancet Healthy Longevity.

PALB2 variant status in hematological malignancies – a potential therapeutic target?

T. Stankovic, G. Stewart, P. Byrd, 2019, Leukemia & lymphoma.

Cytomegalovirus and Human Immune System Aging

P. Moss, 2019, Encyclopedia of Gerontology and Population Aging.

Sociodemographic factors associated with IgG and IgM seroprevalence for human cytomegalovirus infection in adult populations of Pakistan: a seroprevalence survey

P. Moss, E. Lalani, A. Siddiqui, 2016, BMC Public Health.

Optimization of a Human Bacille Calmette-Guérin Challenge Model: A Tool to Evaluate Antimycobacterial Immunity

P. Moss, H. McShane, S. Harris, 2015, The Journal of infectious diseases.

The UPTAKE study: implications for the future of COVID-19 vaccination trial recruitment in UK and beyond

P. Moss, S. Basu, Aditi Kumar, 2021, Trials.

Incidence of SARS-CoV-2 infection according to baseline antibody status in staff and residents of 100 Long Term Care Facilities (VIVALDI study)

A. Copas, P. Moss, C. Fuller, 2021, medRxiv.

Single Vaccination with BNT162b2 or ChAdOx1 in Older People Induces Equivalent Antibody Generation but Enhanced Cellular Responses after ChAdOx1

P. Moss, R. Bruton, S. Faustini, 2021, SSRN Electronic Journal.

Sequence analysis of the human αβ T-cell receptor CDR3 region

J. Bell, P. Moss, 2004, Immunogenetics.

Covid-19 infection in therapy-naive patients with B-cell chronic lymphocytic leukemia

P. Moss, G. Pratt, S. Paneesha, 2020, Leukemia Research.

The genotype of RAET1L (ULBP6), a ligand for human NKG2D (KLRK1), markedly influences the clinical outcome of allogeneic stem cell transplantation

P. Moss, R. Salama, G. Pratt, 2012, British journal of haematology.

CAR-T Comes to the Rescue: Cell Therapy Makes 2018 Headlines in the Management of Relapsed Large B-cell Lymphoma

P. Moss, 2018, The Hematologist.

Transplant Donor KIR Genotype Influences the Rate of CMV Reactivation Following T-Replete Stem Cell Transplantation.

C. Craddock, C. Fegan, P. Moss, 2004 .

Cellular immune responses to influenza.

P. Moss, 2003, Developments in biologicals.

T Cell Protocols: Development and Activation.

P. Moss, 2001 .

History and development of molecular biology

P. Moss, 2019, Molecular Hematology 4e.

CD52/GPI- T-Cells Are Enriched for Alloreactive Specificity and Predict Acute Graft-Versus-Host-Disease After Stem Cell Transplantation.

C. Craddock, P. Moss, R. Malladi, 2021, Transplantation and Cellular Therapy.

ES02.03  Principles of immunotherapy

P. Moss, 2004, Vox Sanguinis.

Phenotypic analysis of antigen-specific T lymphocytes. Science. 1996. 274: 94-96.

Mark M. Davis, J. Bell, P. Goulder, 2011, Journal of immunology.

Profile of maternal CD4 T-cell effector function during normal pregnancy and in women with a history of recurrent miscarriage.

P. Moss, M. Kilby, O. Goodyear, 2014, Clinical science.

The number of human peripheral blood CD4+ CD25high regulatory T cells increases with age

P. Moss, N. Khan, L. Nayak, 2005, Clinical and experimental immunology.

Cytomegalovirus seropositivity is independently associated with cardiovascular disease in non-dialysis dependent chronic kidney disease.

P. Moss, P. Cockwell, C. Ferro, 2020, QJM : monthly journal of the Association of Physicians.

A disease-linked ULBP6 polymorphism inhibits NKG2D-mediated target cell killing by enhancing the stability of NKG2D ligand binding

P. Moss, R. Malladi, M. Davey, 2017, Science Signaling.

University of Birmingham Analysis of the effects of stromal cells on the migration of lymphocytes into and through inflamed tissue using 3-D culture models

P. Moss, G. Nash, G. Rainger, 2014 .

Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma

P. Moss, S. Basu, A. Filer, 2016, Leukemia.

Human Cytomegalovirus: a neglected public health area of significant relevance to women, the foetus and new born. Time for action!

P. Moss, E. Lalani, A. Siddiqui, 2017, JPMA. The Journal of the Pakistan Medical Association.

T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice

T. Stankovic, P. Moss, A. Taylor, 2015, Disease Models & Mechanisms.

Control Of Cytomegalovirus Reactivation Post Stem Cell Transplantation Is Mediated By Simultaneous Reconstitution Of CD4+ and CD8+ CMV-Specific T Cells

C. Craddock, P. Moss, A. Pachnio, 2013 .

Systematic study of human alpha beta T cell receptor V segments shows allelic variations resulting in a large number of distinct T cell receptor haplotypes.

P. Moss, C. Julier, R. Harding, 1993, European journal of immunology.