J. Villadsen

发表

Solution of differential equation models by polynomial approximation

J. Villadsen, M. Michelsen, 1978 .

Modeling isotopomer distributions in biochemical networks using isotopomer mapping matrices.

J. Villadsen, K. Schmidt, M. Carlsen, 1997, Biotechnology and bioengineering.

Solution of boundary-value problems by orthogonal collocation

W. E. Stewart, J. Villadsen, 1995 .

Bioreaction Engineering Principles

J. Nielsen, J. Villadsen, 1994, Springer US.

Solution of parabolic partial differential equations by a double collocation method

John Villadsen, J. Villadsen, J. P. Sørensen, 1969 .

A convenient computational procedure for collocation constants

J. Villadsen, M. Michelsen, J. Villadsen, 1972 .

Flux distributions in anaerobic, glucose-limited continuous cultures of Saccharomyces cerevisiae.

J. Nielsen, J. Nielsen, J. Villadsen, 1997, Microbiology.

Quantitative analysis of metabolic fluxes in Escherichia coli, using two-dimensional NMR spectroscopy and complete isotopomer models.

J. Nielsen, J. Villadsen, K. Schmidt, 1999, Journal of biotechnology.

Growth energetics and metabolic fluxes in continuous cultures of Penicillium chrysogenum.

J. Nielsen, J. Nielsen, J. Villadsen, 1996, Journal of biotechnology.

On-line study of fungal morphology during submerged growth in a small flow-through cell.

J. Nielsen, J. Villadsen, M. Carlsen, 1998, Biotechnology and bioengineering.

Isothermal reaction calorimeters—I. A literature review

J. Villadsen, L. Karlsen, 1987 .

Metabolic flux distributions in Penicillium chrysogenum during fed‐batch cultivations

J Villadsen, J. Nielsen, J. Villadsen, 1995, Biotechnology and bioengineering.

Asymptotic stability of a catalyst particle

J. Villadsen, M. Michelsen, S. Wedel, 1977 .

New Enzymes for Organic Synthesis

G. T. Tsao, T. Scheper, C. Wandrey, 1997 .

Dynamic investigation and modeling of the nitrogen cometabolism in Methylococcus capsulatus ( Bath)

Krist V Gernaey, John Villadsen, Christian Lieven, 2019, Biotechnology and bioengineering.

Determination of the phosphorylated sugars of the Embden-Meyerhoff-Parnas pathway in Lactococcus lactis using a fast sampling technique and solid phase extraction.

J. Villadsen, N. B. Jensen, K. V. Jokumsen, 1999, Biotechnology and bioengineering.

A robust liquid chromatographic method for measurement of medium components during penicillin fermentations

John Villadsen, J. Villadsen, L. H. Christensen, 1994 .

High exogenous concentrations of phenoxyacetic acid are crucial for a high penicillin V productivity in Penicillium chrysogenum.

J. Nielsen, J. Villadsen, C. Henriksen, 1998, Microbiology.

Kinetic studies on the carboxylation of 6-amino-penicillanic acid to 8-hydroxy-penillic acid

J. Nielsen, J. Villadsen, D. Schipper, 1997 .

Delay and dispersion in an in situ membrane probe for bioreactors

J. Villadsen, L. H. Christensen, J. Nielsen, 1991 .

Culture fluorescence measurements during batch and fed-batch cultivations with Penicillium chrysogenum

Jens Nielsen, John Villadsen, J. Nielsen, 1994 .

Bioreactors: Description and Modelling

J. Villadsen, J. Nielsen, 2001 .

Pellet Formation and Fragmentation in Submerged Cultures of Penicillium chrysogenum and Its Relation to Penicillin Production

J. Nielsen, J. Villadsen, M. Jacobsen, 1995, Biotechnology progress.

Kinetics and effectiveness factor for SO2 oxidation on an industrial vanadium catalyst

J. Villadsen, H. Livbjerg, 1972 .

A biochemically structured model for ethanol fermentation by Kluyveromyces marxianus: A batch fermentation and kinetic study.

G. Sin, J. Villadsen, V. Calabrò, 2011, Bioresource technology.

Modeling of Growth Kinetics

John Villadsen, Gunnar Lidén, J. Villadsen, 2003 .

Mixing by rotary jet heads: Indications of the benefits of head rotation under turbulent and transitional flow conditions

K. Gernaey, A. Nienow, J. Villadsen, 2008 .

Modelling of the protonophoric uncoupling by phenoxyacetic acid of the plasma membrane potential of Penicillium chrysogenum.

J Villadsen, J. Nielsen, J. Villadsen, 1998, Biotechnology and bioengineering.

Growth Kinetics of Cell Cultures

J. Nielsen, J. Villadsen, G. Lidén, 2011 .

Anaerobic and aerobic batch cultivations of Saccharomyces cerevisiae mutants impaired in glycerol synthesis

J. Nielsen, J. Villadsen, J. Nielsen, 2000, Yeast.

Chemicals from Metabolic Pathways

J. Nielsen, J. Villadsen, G. Lidén, 2011 .

Acoustic off-gas analyser for bioreactors: Precision, accuracy and dynamics of detection

J. Villadsen, U. Schulze, L. H. Christensen, 1995 .

Modeling and system identification of an unconventional bioreactor used for single cell protein production

B. Bequette, K. Gernaey, J. Villadsen, 2020, Chemical Engineering Journal.

Use of high-gradient magnetic fishing for reducing proteolysis during fermentation.

J. Villadsen, J. Brask, K. Ottow, 2012, Biotechnology journal.

Reflections on the aerobic fermentation stoichiometry of Crabtree positive yeasts.

J. Villadsen, S. Jørgensen, 2014, Biotechnology and bioengineering.

Modeling of Reaction Kinetics

J. Villadsen, J. Nielsen, 1994 .

The kinetics of penicillin‐V deacylation on an immobilized enzyme

J. Villadsen, L. Karlsen, P. Haagensen, 1983, Biotechnology and bioengineering.

Cyclization of α-aminoadipic acid into the δ-lactam 6-oxo-piperidine-2-carboxylic acid by Penicillium chrysogenum

J. Villadsen, C. Henriksen, J. Nielsen, 1998 .

Redox Balances and Consistency Check of Experiments

J. Villadsen, 2015 .

Production of optically pure d-lactate by Lactobacillus bulgaricus and purification by crystallisation and liquid/liquid extraction

J. Villadsen, S. Benthin, 1995, Applied Microbiology and Biotechnology.

System wide cofactor turnovers can propagate metabolic stability between pathways

J. Villadsen, Y. Guan, Y. Guan, 2016, Metabolic engineering communications.

Falsification of kinetic parameters by incorrect treatment of recirculation reactor data

J. Villadsen, S. Wedel, 1983 .

The effectiveness factor for an isothermal pellet with decreasing activity towards the pellet surface

J. Villadsen, 1976 .

The level of pyruvate-formate lyase controls the shift from homolactic to mixed-acid product formation in Lactococcus lactis

J. Villadsen, H. Israelsen, J. Arnau, 2002, Applied Microbiology and Biotechnology.

Dynamics of pyruvate metabolism in Lactococcus lactis.

B. Christensen, J. Villadsen, N. B. Jensen, 2001, Biotechnology and bioengineering.

Two Uptake Systems for Fructose in Lactococcus lactis subsp. cremoris FD1 Produce Glycolytic and Gluconeogenic Fructose Phosphates and Induce Oscillations in Growth and Lactic Acid Formation

J. Villadsen, J. Nielsen, S. Benthin, 1993, Applied and environmental microbiology.

Kinetics of Bio‐Reactions

J. Villadsen, 2015 .

Computer Controlled System for On-line Monitoring of a Fermentation Process

J. Villadsen, J. Nielsen, K. Nikolajsen, 1989 .

Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2‐oxoglutarate due to depletion of the NADPH pool

J. Nielsen, J. Villadsen, T. L. Nissen, 2001, Yeast.

Growth and α-amylase production by Aspergillus oryzae during continuous cultivations

J. Nielsen, J. Villadsen, M. Carlsen, 1996 .

Morphology and physiology of an α‐amylase producing strain of Aspergillus oryzae during batch cultivations

J. Nielsen, J. Villadsen, M. Carlsen, 2000, Biotechnology and bioengineering.

Oxidation of lactose to lactobionic acid by a Microdochium nivale carbohydrate oxidase: Kinetics and operational stability

John Villadsen, Mikkel Nordkvist, Per Munk Nielsen, 2007, Biotechnology and bioengineering.

Growth and Protein Formation of Recombinant Aspergillus: Utility of Morphological Characterization by Image Analysis

J. Nielsen, J. Villadsen, M. Carlsen, 1994 .

FIA for on‐line monitoring of important lactic acid fermentation variables

J Villadsen, J. Villadsen, K Nikolajsen, 1989, Biotechnology and bioengineering.

In-line flow injection analysis for monitoring lactic acid fermentations

John Villadsen, J. Villadsen, Karin Nikolajsen, 1988 .

Diffusion and reaction on spherical catalyst pellets: steady state- and local stability analysis

J. Villadsen, M. Michelsen, 1972 .

Enzyme Kinetics and Metabolic Control Analysis

J. Villadsen, G. Lidén, J. Nielsen, 2003 .

Numerical Methods in Chemical Reaction Engineering

J. Villadsen, 1981 .

Physiological effects of nitrogen starvation in an anaerobic batch culture of Saccharomyces cerevisiae.

J Villadsen, J. Nielsen, J. Villadsen, 1996, Microbiology.

An analysis of the multiplicity pattern of models for simultaneous diffusion, chemical reaction and absorption

J. Villadsen, P. Nielsen, 1985 .

A note on the multiplicity of the Weisz-Hicks problem for an arbitrary “geometry factor”

J. Villadsen, E. Ivanov, 1978 .

Models for strongly exothermic absorption and reaction in falling films

J. Villadsen, P. Nielsen, 1986 .

Absorption with exothermic reaction in a falling film column

J. Villadsen, P. Nielsen, 1983 .

Approximate solution of extended Graetz problem by orthogonal collocation

J. Villadsen, J. Villadsen, M. L. Michelson, 1976 .

The Graetz problem with axial heat conduction

John Villadsen, Michael L. Michelsen, J. Villadsen, 1974 .

Challenges and cul−de−sacs in reactor modelling

J. Villadsen, 1988 .

Influence of the Dissolved Oxygen Concentration on the Penicillin Biosynthetic Pathway in Steady‐State Cultures of Penicillium chrysogenum

Jens Nielsen, John Villadsen, Claus Maxel Henriksen, 1997 .

An automated glucose isomerase reactor system with online flow injection analyzers for monitoring of pH, glucose and fructose concentrations

J. Villadsen, J. Gram, Michael de Bang, 1990 .

Optimization of ethanol production in Saccharomyces cerevisiae by metabolic engineering of the ammonium assimilation.

J Villadsen, J. Nielsen, J. Nielsen, 2000, Metabolic engineering.

Oxidative phosphorylation revisited

J. Villadsen, S. Nath, 2015, Biotechnology and bioengineering.

On-line monitoring of glucose and penicillin by sequential injection analysis

John Villadsen, J. Villadsen, Jens Nielsen, 1996 .

Optimal fed-batch cultivation when mass transfer becomes limiting.

John Villadsen, K. Patil, J. Villadsen, 2007, Biotechnology and bioengineering.

Cyclization of α‐Aminoadipic Acid into the δ‐Lactam 6‐Oxo‐piperidine‐2‐carboxylic Acid by Penicillium chrysogenum

J. Villadsen, C. Henriksen, J. Nielsen, 1998 .

Determination of intracellular trehalose and glycogen in Saccharomyces cerevisiae.

J Villadsen, J. Villadsen, U. Schulze, 1995, Analytical biochemistry.

Synthesis and Posttranslational Regulation of Pyruvate Formate-Lyase in Lactococcus lactis

J. Villadsen, H. Israelsen, J. Arnau, 2000, Journal of bacteriology.

A computational technique for simulating the dynamic response of a flow injection analysis system

John Villadsen, Steven Howard Isaacs, J. Villadsen, 1992 .

Monitoring of substrates and products during fed-batch penicillin fermentations on complex media

John Villadsen, J. Villadsen, L. H. Christensen, 1991 .

Single cell protein production from C1 compounds.

J. Villadsen, L. Ekeroth, 1991, Biotechnology.

Glucose Metabolism in Lactococcus lactis MG1363 under Different Aeration Conditions: Requirement of Acetate To Sustain Growth under Microaerobic Conditions

J. Villadsen, N. B. Jensen, Mikkel Nordkvist, 2003, Applied and Environmental Microbiology.

Metabolic Behavior of Lactococcus lactis MG1363 in Microaerobic Continuous Cultivation at a Low Dilution Rate

J. Villadsen, N. B. Jensen, K. V. Jokumsen, 2001, Applied and Environmental Microbiology.

Modelling of microbial kinetics

John Villadsen, Jens Nielsen, J. Villadsen, 1992 .

Simulation of the vertical flow of a thin, wavy film using a finite-element method

J. Villadsen, P. Bach, 1984 .

Semi-on-line analysis for fast and precise monitoring of bioreaction processes.

J Villadsen, L H Christensen, J Marcher, 2000, Biotechnology and bioengineering.

Scale-Up of Bioprocesses

John Villadsen, Gunnar Lidén, Jens Nielsen, 2011 .

Anomeric specificity of glucose uptake systems in Lactococcus cremoris, Escherichia coli, and Saccharomyces cerevisiae: Mechanism, kinetics, and lmplications

J Villadsen, J. Nielsen, J. Villadsen, 1992, Biotechnology and bioengineering.

Experiments with Methyl-fluoro-phosphorylcholine-inhibited Cholinesterase.

J. Villadsen, E. Diczfalusy, L. G. Sillén, 1958 .

Simultaneous monitoring of glucose, lactic acid and penicillin by sequential injection analysis

John Villadsen, J. Villadsen, Jens Nielsen, 1995 .

Use of continuous lactose fermentation for ethanol production by Kluveromyces marxianus for verification and extension of a biochemically structured model.

G. Sin, J. Villadsen, S. Curcio, 2013, Bioresource technology.

Amino acid utilization by Lactococcus lactis subsp. cremoris FD1 during growth on yeast extract or casein peptone

J. Villadsen, S. Benthin, 1996 .

A novel technique based on 85Kr for quantification of gas—liquid mass transfer in bioreactors

J. Villadsen, J. Nielsen, A. G. Pedersen, 1994 .

Bioreactors : a chemical engineering perspective

John Villadsen, T. M. Leib, Carmo J. Pereira, 2001 .

Cellular Growth Reactions

J. Villadsen, J. Nielsen, 1994 .

Scale‐up of enzymatic production of lactobionic acid using the rotary jet head system

John Villadsen, Mikkel Nordkvist, Per Munk Nielsen, 2007, Biotechnology and bioengineering.

Expression of the Escherichia coli pntA andpntB Genes, Encoding Nicotinamide Nucleotide Transhydrogenase, in Saccharomyces cerevisiae and Its Effect on Product Formation during Anaerobic Glucose Fermentation

J. Nielsen, J. Villadsen, B. Hahn-Hägerdal, 1999, Applied and Environmental Microbiology.

Solution of partial differential equations systems by the moving finite element method

Alírio E. Rodrigues, John Villadsen, Carlos Sereno, 1992 .

The moving finite element method with polynomial approximation of any degree

Alírio E. Rodrigues, John Villadsen, Carlos Sereno, 1991 .

Lactic Acid Production

J. Villadsen, 2000 .

Distribution of D- and L-Amino Acids along the Chain of Poly-DL-Alanine.

J. Villadsen, E. Diczfalusy, L. G. Sillén, 1958 .

On the use of population balances

J. Villadsen, J. Villadsen, 1999 .

Theoretical foundation of cluster formation in supported liquid-phase catalysts

J. Villadsen, T. Christensen, T. T. Hansen, 1987 .

Sulfur dioxide oxidation on supported molten V2O5K2S2O7 catalyst: Influence of liquid diffusion resistance

K. Jensen, J. Villadsen, H. Livbjerg, 1976 .

Liquid Dispersion, Mass Transport, and Chemical Reaction in Supported Liquid Phase Catalysts for SO2Oxidation

J. Villadsen, B. Sørensen, H. Livbjerg, 1975 .

Quantification of intracellular metabolic fluxes from fractional enrichment and 13C-13C coupling constraints on the isotopomer distribution in labeled biomass components.

J Villadsen, K Schmidt, J. Villadsen, 1999, Metabolic engineering.

Biochemical Reaction Networks

Jens Nielsen, John Villadsen, Gunnar Lidén, 2011 .

Dual Reactor Investigation of SO2-Oxidation with a V2O5/K2S2O7 Catalyst

J. Villadsen, H. Livbjerg, Jesper L. Sørensen, 1988 .

Steady state operation of a dual-reactor system with liquid catalyst

J. Villadsen, H. Livbjerg, M. J. Peytz, 1982 .

SULFUR DIOXIDE OXIDATION ON SUPPORTED MOLTEN VANADIUM PENTOXIDE-POTASSIUM PYROSULFATE CATALYST. INFLUENCE OF LIQUID DIFFUSION RESISTANCE

K. Jensen, J. Villadsen, H. Livbjerg, 1977 .

A correction procedure for interparticle gradients in a laboratory catalytic recirculation reactor

J. Villadsen, H. Livbjerg, M. Pirjamali, 1973 .

Internal recirculation reactor for the oxidation of sulphur dioxide on vanadium catalysts

J. Villadsen, H. Livbjerg, 1971 .

Modeling dynamics of chemical reaction networks using electrical analogs: Application to autocatalytic reactions

J. Villadsen, S. Nath, 2022, Chemical Engineering Journal Advances.

Modeling fermentations with recombinant microorganisms: Formulation of a structured model

John Villadsen, Jens Nielsen, J. Nielsen, 1991, Biotechnology and bioengineering.

Population Balance Equations

J. Nielsen, J. Villadsen, G. Lidén, 2011 .

Structured modeling of a microbial system: III. Growth on mixed substrates

J. Nielsen, J. Villadsen, K. Nikolajsen, 1991, Biotechnology and bioengineering.

Elemental and Redox Balances

Jens Nielsen, John Villadsen, Gunnar Lidén, 2011 .

On the Optimal Design and Control of a Biodegradation Process with Substrate Inhibition Kinetics

John Villadsen, J. Villadsen, 1999 .

Optimization of a reactor assembly for the production of 6‐APA from penicillin‐V

J. Villadsen, L. Karlsen, 1984, Biotechnology and bioengineering.

Monitoring and control of fed-batch penicillin fermentation

Jens Nielsen, John Villadsen, Claus Lindvald Johansen, 1992 .

Flow-injection analysis of micromolar concentrations of glucose and lactate in fermentation media

John Villadsen, J. Villadsen, Jens Nielsen, 1992 .

Characterization and application of precise and robust flow-injection analysers for on-line measurement during fermentations

John Villadsen, J. Villadsen, Jens Nielsen, 1991 .

Application of flow-injection analysis in the on-line monitoring of sugars, lactic acid, protein and biomass during lactic acid fermentations

John Villadsen, J. Villadsen, Karin Nikolajsen, 1990 .

Mixing and mass transfer in a pilot scale U‐loop bioreactor

John Villadsen, K. Gernaey, J. Villadsen, 2017, Biotechnology and bioengineering.

Preparation and Characterization of Small Iron Particles Supported on MgO

J. Villadsen, J. Dumesic, S. Mørup, 1979 .

α-Amylase production in recombinant Aspergillus oryzae during fed-batch and continuous cultivations

Jens Nielsen, John Villadsen, J. Nielsen, 1998 .

Mixing and Mass Transfer in Industrial Bioreactors

J. Villadsen, 2015 .

Applying rotary jet heads for mixing and mass transfer in a forced recirculation tank reactor system

John Villadsen, Thomas Grotkjær, Mikkel Nordkvist, 2003 .

A simple and reliable method for the determination of cellular RNA content

Jens Nielsen, John Villadsen, J. Nielsen, 1991 .

Galactose Expulsion during Lactose Metabolism in Lactococcus lactis subsp. cremoris FD1 Due to Dephosphorylation of Intracellular Galactose 6-Phosphate

J. Villadsen, J. Nielsen, S. Benthin, 1994, Applied and environmental microbiology.

Different inhibition of Lactobacillus delbrueckii subsp. bulgaricus by D- and L-lactic acid : effects on lag phase, growth rate and cell yield

J. Villadsen, S. Benthin, 1995 .

Single-Cell Protein Production in a U-Loop Reactor

Sten Bay Jørgensen, John Bagterp Jørgensen, Dres Foged Olsen, 2010 .

Computer aided modelling of complex fermentation processes

John Villadsen, J. Villadsen, 1992 .

Morphologically Structured Models

J. Villadsen, J. Nielsen, 1994 .

Analysis of Reaction Rates

J. Villadsen, J. Nielsen, 1994 .

Thermodynamics of Bioreactions

John Villadsen, Gunnar Lidén, Jens Nielsen, 2011 .

Glucose/citrate cometabolism in Lactococcus lactis subsp. lactis biovar diacetylactis with impaired alpha-acetolactate decarboxylase.

J. Villadsen, D. Nilsson, C. Henriksen, 1999, Metabolic engineering.

Continuous cultivation of Penicillium chrysogenum. Growth on glucose and penicillin production.

J Villadsen, J. Nielsen, J. Villadsen, 1995, Journal of biotechnology.

Growth energetics of Lactococcus cremoris FD1 during energy-, carbon-, and nitrogen-limitation in steady state and transient cultures

J. Villadsen, U. Schulze, J. Nielsen, 1994 .

Transport of sugars via two anomer‐specific sites on mannose–phosphotransferase system in Lactococcus cremoris: In vivo study of mechanism, kinetics, and adaptation

J. Nielsen, J. Villadsen, S. Benthin, 1993, Biotechnology and bioengineering.

Thermodynamics and kinetics of lipase catalysed hydrolysis of oleyl oleate.

J. Villadsen, L. Pedersen, T. Rostrup-Nielsen, 2007, Journal of chemical technology and biotechnology.

Surface Tension of Liquid Mixtures. A Micro-Method Applied to the Systems: Chloroform-Carbon-tetrachloride, Benzene-Diphenylmethane, and Heptane-Hexadecane.

J. Villadsen, E. Diczfalusy, L. G. Sillén, 1958 .

Dynamics of ammonia uptake in nitrogen limited anaerobic cultures of Saccharomyces cerevisiae.

J. Villadsen, G. Lidén, U. Schulze, 1996, Journal of biotechnology.

Biochemical Reactions — A First Look

J. Nielsen, J. Villadsen, G. Lidén, 2003 .

Gas–Liquid Mass Transfer

J. Nielsen, J. Villadsen, G. Lidén, 2011 .

Structured modeling of a microbial system: I. A theoretical study of lactic acid fermentation

J Villadsen, J. Villadsen, J Nielsen, 1991, Biotechnology and bioengineering.

Kinetic studies of acid-inactivation of α-amylase from Aspergillus oryzae

J. Villadsen, M. Carlsen, J. Nielsen, 1996 .

13C tracer experiments and metabolite balancing for metabolic flux analysis: comparing two approaches

Sahm, J. Villadsen, K. Schmidt, 1998, Biotechnology and bioengineering.