C. H. Nielsen

发表

Twist1 Suppresses Senescence Programs and Thereby Accelerates and Maintains Mutant Kras-Induced Lung Tumorigenesis

P. Tamayo, C. Rudin, A. Sweet-Cordero, 2012, PLoS genetics.

Matrix-insensitive protein assays push the limits of biosensors in medicine

Boris Murmann, Sanjiv S Gambhir, Joseph C Liao, 2009, Nature Medicine.

New positron emission tomography (PET) radioligand for imaging σ-1 receptors in living subjects.

S. Gambhir, C. H. Nielsen, M. James, 2012, Journal of medicinal chemistry.

Positron Emission Tomography of 64Cu-DOTA-Rituximab in a Transgenic Mouse Model Expressing Human CD20 for Clinical Translation to Image NHL

A. Iagaru, S. Gambhir, M. Goris, 2012, Molecular Imaging and Biology.

Evaluation of σ-1 Receptor Radioligand 18F-FTC-146 in Rats and Squirrel Monkeys Using PET

D. M. Lyons, S. Gambhir, C. H. Nielsen, 2014, The Journal of Nuclear Medicine.

Site-specifically labeled 89Zr-DFO-trastuzumab improves immuno-reactivity and tumor uptake for immuno-PET in a subcutaneous HER2-positive xenograft mouse model

C. H. Nielsen, A. Kjaer, C. Christensen, 2019, Theranostics.

The Apolipoprotein M/S1P Axis Controls Triglyceride Metabolism and Brown Fat Activity.

C. H. Nielsen, B. Holst, A. Kjaer, 2018, Cell reports.

Uremia does not affect neointima formation in mice

C. H. Nielsen, A. Kjaer, I. Bot, 2017, Scientific Reports.

Quantitative PET imaging of PD-L1 expression in xenograft and syngeneic tumour models using a site-specifically labelled PD-L1 antibody

C. H. Nielsen, A. Kjaer, C. Christensen, 2019, European Journal of Nuclear Medicine and Molecular Imaging.

In vivo imaging of therapy response to a novel Pan-HER antibody mixture using FDG and FLT positron emission tomography

C. H. Nielsen, A. Kjaer, Mette Jensen, 2015, Oncotarget.

[64Cu]‐labelled trastuzumab: optimisation of labelling by DOTA and NODAGA conjugation and initial evaluation in mice

P. Højrup, C. H. Nielsen, Søren Heissel, 2015, Journal of labelled compounds & radiopharmaceuticals.

The Initial Cardiac Tissue Response to Cryopreserved Allogeneic Adipose Tissue-Derived Mesenchymal Stromal Cells in Rats with Chronic Ischemic Cardiomyopathy

J. Kastrup, C. H. Nielsen, A. Kjaer, 2021, International journal of molecular sciences.

A Titratable Two-Step Transcriptional Amplification Strategy for Targeted Gene Therapy Based on Ligand-Induced Intramolecular Folding of a Mutant Human Estrogen Receptor

S. Gambhir, C. H. Nielsen, I. Y. Chen, 2014, Molecular Imaging and Biology.

Quantitative PET Imaging of Tissue Factor Expression Using 18F-Labeled Active Site–Inhibited Factor VII

C. H. Nielsen, A. Kjaer, J. Madsen, 2016, The Journal of Nuclear Medicine.

Neodymium-140 DOTA-LM3

C. H. Nielsen, A. Kjær, K. Johnston, 2018 .

Neodymium-140 DOTA-LM3: Evaluation of an In Vivo Generator for PET with a Non-Internalizing Vector

C. H. Nielsen, A. Kjær, K. Johnston, 2017, Front. Med..

PET Imaging of Tissue Factor in Pancreatic Cancer Using 64Cu-Labeled Active Site–Inhibited Factor VII

C. H. Nielsen, A. Kjaer, J. Madsen, 2016, The Journal of Nuclear Medicine.

Tumor cell MT1-MMP is dispensable for osteosarcoma tumor growth, bone degradation and lung metastasis

C. H. Nielsen, S. V. van Putten, A. Kjaer, 2020, Scientific Reports.

Oxime Coupling of Active Site Inhibited Factor Seven with a Nonvolatile, Water-Soluble Fluorine-18 Labeled Aldehyde.

C. H. Nielsen, C. Behrens, A. Kjaer, 2019, Bioconjugate chemistry.

Affinity-Guided Conjugation to Antibodies for Use in Positron Emission Tomography.

C. H. Nielsen, K. Gothelf, A. Kjaer, 2019, Bioconjugate chemistry.

Combination of [177Lu]Lu-DOTA-TATE Targeted Radionuclide Therapy and Photothermal Therapy as a Promising Approach for Cancer Treatment: In Vivo Studies in a Human Xenograft Mouse Model

C. H. Nielsen, C. Christensen, J. Jørgensen, 2022, Pharmaceutics.

The use of dynamic nuclear polarization (13)C-pyruvate MRS in cancer.

C. H. Nielsen, A. Hansen, H. Johannesen, 2015, American journal of nuclear medicine and molecular imaging.

Bringing Radiotracing to Titanium-Based Antineoplastics: Solid Phase Radiosynthesis, PET and ex Vivo Evaluation of Antitumor Agent [(45)Ti](salan)Ti(dipic).

C. H. Nielsen, A. Kjær, A. I. Jensen, 2015, Journal of medicinal chemistry.

Monitoring CD8a+ T Cell Responses to Radiotherapy and CTLA-4 Blockade Using [64Cu]NOTA-CD8a PET Imaging

C. H. Nielsen, A. Kjaer, C. Christensen, 2020, Molecular Imaging and Biology.

MicroRNA-Regulated Non-Viral Vectors with Improved Tumor Specificity in an Orthotopic Rat Model of Hepatocellular Carcinoma

L. Hofmann, S. Gambhir, C. H. Nielsen, 2013, Gene Therapy.

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine.

M. Mann, D. Drucker, C. H. Nielsen, 2019, Cell metabolism.

CD4+ and CD8a+ PET imaging predicts response to novel PD-1 checkpoint inhibitor: studies of Sym021 in syngeneic mouse cancer models

C. H. Nielsen, A. Kjaer, C. Christensen, 2019, Theranostics.

A blood biomarker for monitoring response to anti-EGFR therapy.

Sharon S. Hori, S. Gambhir, C. H. Nielsen, 2018, Cancer biomarkers : section A of Disease markers.

Darolutamide Potentiates the Antitumor Efficacy of a PSMA-targeted Thorium-227 Conjugate by a Dual Mode of Action in Prostate Cancer Models

J. Karlsson, A. Schlicker, C. H. Nielsen, 2021, Clinical Cancer Research.

First-in-human uPAR PET: Imaging of Cancer Aggressiveness

C. H. Nielsen, S. Holm, A. Kjaer, 2015, Theranostics.

Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis

Xianlin Han, T. Hansen, O. Pedersen, 2018, Cell metabolism.

Targeted microbubbles for imaging tumor angiogenesis: assessment of whole-body biodistribution with dynamic micro-PET in mice.

Sanjiv S Gambhir, Zhen Cheng, Jürgen K Willmann, 2008, Radiology.

Immunostimulatory effects of targeted thorium-227 conjugates as single agent and in combination with anti-PD-L1 therapy

J. Karlsson, A. Schlicker, C. H. Nielsen, 2021, Journal for ImmunoTherapy of Cancer.

Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy

Ahmad Y. Sheikh, J. Willmann, C. H. Nielsen, 2010, Gene Therapy.

The apolipoprotein M/S1P axis controls triglyceride metabolism and brown fat activity

C. H. Nielsen, B. Holst, C. Christoffersen, 2018, Atherosclerosis.

Imaging gene expression in human mesenchymal stem cells: from small to large animals.

A. Yeung, P. Yock, J. Willmann, 2009, Radiology.

Hypoxia-Inducible Factor-1&agr; Expression in Macrophages Promotes Development of Atherosclerosis

C. H. Nielsen, C. Christoffersen, L. Nielsen, 2016, Arteriosclerosis, thrombosis, and vascular biology.

[68Ga]Ga-NODAGA-E[(cRGDyK)]2 and [64Cu]Cu-DOTATATE PET Predict Improvement in Ischemic Cardiomyopathy

C. H. Nielsen, T. Binderup, A. Ekblond, 2023, Diagnostics.

MRS in cancer

C. H. Nielsen, A. Hansen, H. Johannesen, 2015 .

Preclinical evaluation of Raman nanoparticle biodistribution for their potential use in clinical endoscopy imaging.

Robert Sinclair, Sanjiv S Gambhir, Zhen Cheng, 2011, Small.

Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

T. Hansen, O. Pedersen, N. Grarup, 2021, Cell.

PET imaging of tumor neovascularization in a transgenic mouse model with a novel 64Cu-DOTA-knottin peptide.

S. Gambhir, D. Felsher, P. Tran, 2010, Cancer research.

PET in vivo generators 134Ce and 140Nd on an internalizing monoclonal antibody probe

C. H. Nielsen, A. Kjær, A. Mazar, 2022, Scientific Reports.

First-in-Humans PET Imaging of Tissue Factor in Patients with Primary and Metastatic Cancers Using 18F-labeled Active-Site Inhibited Factor VII (18F-ASIS): Potential as Companion Diagnostic

C. H. Nielsen, A. Kjaer, C. Christensen, 2022, The Journal of Nuclear Medicine.

Site-Specific 64Cu Labeling of the Serine Protease, Active Site Inhibited Factor Seven Azide (FVIIai-N3), Using Copper Free Click Chemistry.

C. H. Nielsen, C. Behrens, A. Kjaer, 2017, Bioconjugate chemistry.

Cancer esearch rated Systems and Technologies Imaging of Tumor Neovascularization in a Transgenic R se Model with a Novel 64 Cu-DOTA-Knottin Peptide

S. Gambhir, D. Felsher, P. Tran, 2010 .

Cancer esearch rated Systems and Technologies Imaging of Tumor Neovascularization in a Transgenic R se Model with a Novel 64 Cu-DOTA-Knottin Peptide

S. Gambhir, D. Felsher, P. Tran, 2010 .