S. Ong

发表

GUItars: A GUI Tool for Analysis of High-Throughput RNA Interference Screening Data

Asli N. Goktug, S. Ong, Taosheng Chen, 2012, PloS one.

Blocking an N-terminal acetylation–dependent protein interaction inhibits an E3 ligase

Asli N. Goktug, J. Harper, J. Paulo, 2017, Nature chemical biology.

Pregnane X Receptor in Drug Development

S. Ong, Taosheng Chen, S. Chai, 2011 .

Role of CAR and PXR in xenobiotic sensing and metabolism

S. Ong, Taosheng Chen, S. Chai, 2012, Expert opinion on drug metabolism & toxicology.

Identification and characterization of phosphorylation sites within the pregnane X receptor protein.

S. Ong, Taosheng Chen, Junmin Peng, 2014, Biochemical pharmacology.

Multikinase Inhibitors Induce Cutaneous Toxicity through OAT6-Mediated Uptake and MAP3K7-Driven Cell Death.

M. Maitland, S. Ong, Taosheng Chen, 2016, Cancer research.

The SH3 Domain of Lck Modulates T-Cell Receptor-Dependent Activation of Extracellular Signal-Regulated Kinase through Activation of Raf-1

Bartek Rajwa, S. Ong, R. Geahlen, 2007, Molecular and Cellular Biology.

Cyclin-Dependent Kinase 4 Phosphorylates and Positively Regulates PAX3-FOXO1 in Human Alveolar Rhabdomyosarcoma Cells

S. Ong, Taosheng Chen, Lingling Liu, 2013, PloS one.

A phosphotyrosine switch regulates organic cation transporters

E. Isacoff, A. Sali, S. Ong, 2016, Nature Communications.

Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1.

S. Ong, Taosheng Chen, E. Schuetz, 2013, Toxicology and applied pharmacology.

Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2.

Asli N. Goktug, S. Ong, Taosheng Chen, 2014, The Biochemical journal.

Serine 350 of human pregnane X receptor is crucial for its heterodimerization with retinoid X receptor alpha and transactivation of target genes in vitro and in vivo.

S. Ong, Taosheng Chen, E. Schuetz, 2015, Biochemical pharmacology.

Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox.

Jie J. Zheng, D. Green, Chunxu Qu, 2017, Cancer research.

Mitigation of acute kidney injury by cell-cycle inhibitors that suppress both CDK4/6 and OCT2 functions

S. Ong, Taosheng Chen, A. Gibson, 2015, Proceedings of the National Academy of Sciences.

Transcription factor ZNF148 is a negative regulator of human muscle differentiation

S. Ong, Taosheng Chen, P. Thomas, 2017, Scientific Reports.

Regulation of Syk by Phosphorylation on Serine in the Linker Insert*

S. Ong, W. Tao, R. Geahlen, 2010, The Journal of Biological Chemistry.

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury

S. Cobb, S. Ong, Taosheng Chen, 2020, Nature Communications.

Regulation of OATP1B1 Function by Tyrosine Kinase–mediated Phosphorylation

S. Ong, Taosheng Chen, A. Gibson, 2021, Clinical Cancer Research.

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury

S. Cobb, S. Ong, Taosheng Chen, 2020, Nature Communications.