M. Kunkel

发表

Comprehensive characterization of the Published Kinase Inhibitor Set

John P. Overington, D. J. Price, N. Sepetov, 2016, Nature Biotechnology.

Cell‐free heterologous desensitization of adenylyl cyclase in S49 lymphoma cell membranes mediated by cAMP‐dependent protein kinase

S. Shenolikar, M. Kunkel, J. Friedman, 1989, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Activation of cAMP-dependent protein kinase is required for heterologous desensitization of adenylyl cyclase in S49 wild-type lymphoma cells.

M. Kunkel, J. Johnson, J. Friedman, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression.

A. Monks, Dmitriy Sonkin, Joel Morris, 2016, Journal of the National Cancer Institute.

Molecular Methods for Human Leukocyte Antigen Typing: Current Practices and Future Directions

D. Monos, M. Kunkel, J. Duke, 2016 .

Role of Protein Kinases in the Desensitization-Sensitization of β-Adrenergic Receptor and Prostaglandin Receptor Stimulation of Adenylyl Cyclase

M. Kunkel, R. Clark, J. Friedman, 1990 .

β‐Adrenergic receptor desensitization of wild‐type but not cyc lymphoma cells unmasked by submillimolar Mg2+

M. Kunkel, J. Johnson, J. Friedman, 1987, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inhibition of the epidermal growth factor receptor tyrosine kinase by PD153035 in human A431 tumors in athymic nude mice

M. Kunkel, W. Elliott, B. J. Roberts, 1995, Investigational New Drugs.

Mechanisms of inhibition of the thioredoxin growth factor system by antitumor 2-imidazolyl disulfides.

M. Kunkel, D. Kirkpatrick, G. Powis, 1998, Biochemical pharmacology.

Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

P. Meltzer, W. Reinhold, Y. Pommier, 2020, Clinical Epigenetics.

Antitumor activity of bis-indole derivatives.

M. Kunkel, H. Fiebig, L. Landi, 2008, Journal of medicinal chemistry.

3-Deoxy-D-myo-inositol 1-phosphate, 1-phosphonate, and ether lipid analogues as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth.

M. Kunkel, F. Nan, G. Powis, 1998, Journal of medicinal chemistry.

3Beta-hydroxy-6-aza-cholestane and related analogues as phosphatidylinositol specific phospholipase C (PI-PLC) inhibitors with antitumor activity.

Y. Li, M. Kunkel, G. Powis, 2000, Bioorganic & medicinal chemistry.

Structure-activity relationship of aza-steroids as PI-PLC inhibitors.

M. Kunkel, G. Powis, L. Zalkow, 2001, Bioorganic & medicinal chemistry.

Antitumor activity of substituted E-3-(3,4,5-trimethoxybenzylidene)-1,3-dihydroindol-2-ones1.

M. Kunkel, A. Andreani, M. Granaiola, 2006, Journal of medicinal chemistry.

Synthesis and Antitumor Activity of Guanylhydrazones from 6-(2,4-Dichloro-5-nitrophenyl)imidazo[2,1-b]thiazoles and 6-Pyridylimidazo[2,1-b]thiazoles1

M. Kunkel, L. Masotti, C. Stefanelli, 2006 .

Sarcoma Cell Line Screen of Oncology Drugs and Investigational Agents Identifies Patterns Associated with Gene and microRNA Expression

A. Monks, Joel Morris, B. Teicher, 2015, Molecular Cancer Therapeutics.

The dichotomy between disease phenotype databases and the implications for understanding complex diseases involving the major histocompatibility complex

D. Monos, M. Kunkel, P. Clark, 2015, International journal of immunogenetics.

Global Mapping of Transposon Location

David Gresham, Stephen C Pratt, Johannes Dapprich, 2006, PLoS genetics.

Single-Molecule Rapid Imaging of Linear Genomes in Nanochannel Array

A. Hastie, M. Kunkel, H. Cao, 2011 .

cDNA microarray analysis of multidrug resistance: doxorubicin selection produces multiple defects in apoptosis signaling pathways.

M. Kunkel, B. Futscher, S. Salmon, 2001, The Journal of pharmacology and experimental therapeutics.

Laminin‐5–mediated gene expression in human prostate carcinoma cells

M. Kunkel, A. Cress, G. T. Bowden, 2001, Molecular carcinogenesis.

Cell line-directed screening assay for inhibitors of thioredoxin reductase signaling as potential anti-cancer drugs.

M. Kunkel, D. Kirkpatrick, G. Powis, 1997, Anti-cancer drug design.

Parallel syntheses of disulfide inhibitors of the thioredoxin redox system as potential antitumor agents.

M. Kunkel, D. Kirkpatrick, G. Powis, 1999, Anti-cancer drug design.

Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages - strategies for data mining in support of therapeutic studies

Gurmeet Kaur, D. Newton, M. Mullendore, 2014, BMC Genomics.

Identification of an autostimulatory growth factor in the extracts and conditioned medium of GH3/C14 rat pituitary cells in culture.

M. Kunkel, D. Danielpour, D. Sirbasku, 1984, Endocrinology.

SNP-specific extraction of haplotype-resolved targeted genomic regions

D. Monos, M. Kunkel, D. Ferriola, 2008, Nucleic Acids Research.

Okadaic acid induces both augmentation and inhibition of beta 2-adrenergic stimulation of cAMP accumulation in S49 lymphoma cells.

S. Shenolikar, M. Kunkel, J. Friedman, 1993, The Journal of biological chemistry.

F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd

Joel Morris, B. Teicher, M. Kunkel, 2021, Molecular Cancer Therapeutics.

Redox active disulfides: the thioredoxin system as a drug target.

M. Kunkel, D. Kirkpatrick, G. Powis, 1997, Oncology research.

Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets

P. Meltzer, W. Reinhold, Y. Pommier, 2020, Clinical Epigenetics.