L. Le

发表

Crizotinib in ROS 1-Rearranged Non – Small-Cell Lung Cancer

Jeffrey W. Clark, A. Iafrate, A. Shaw, 2014 .

Crizotinib in ROS1-rearranged non-small-cell lung cancer.

Jeffrey W. Clark, A. Iafrate, A. Shaw, 2014, The New England journal of medicine.

Anchored multiplex PCR for targeted next-generation sequencing

A. Iafrate, W. Pao, J. Engelman, 2014, Nature Medicine.

Standardized decision support in next generation sequencing reports of somatic cancer variants

Rodrigo Dienstmann, Fei Dong, Long P Le, 2014, Molecular oncology.

Health Care Infrastructure for Financially Sustainable Clinical Genomics.

Jeffrey A. Golden, H. Rehm, A. Iafrate, 2016, The Journal of molecular diagnostics : JMD.

Diagnostic Value of MAML2 Rearrangements in Mucoepidermoid Carcinoma

Cameron R. Smith, Lauren L. Ritterhouse, A. Iafrate, 2022, International journal of molecular sciences.

Clinically Integrated Molecular Diagnostics in Adenoid Cystic Carcinoma

A. Iafrate, D. Dias-Santagata, L. Le, 2019, The oncologist.

Apocrine-Eccrine Carcinomas: Molecular and Immunohistochemical Analyses

A. Iafrate, M. Mihm, D. Dias-Santagata, 2012, PloS one.

Detection of Dual IDH1 and IDH2 Mutations by Targeted Next-Generation Sequencing in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

Mia Y. Platt, A. Iafrate, S. Yip, 2015, The Journal of molecular diagnostics : JMD.

BRAF V600E status adds incremental value to current risk classification systems in predicting papillary thyroid carcinoma recurrence.

L. Le, G. Daniels, S. Parangi, 2012, Surgery.

Proliferative Nodules Arising Within Congenital Melanocytic Nevi: A Histologic, Immunohistochemical, and Molecular Analyses of 43 Cases

M. Mihm, P. Kapur, D. Rakheja, 2011, The American journal of surgical pathology.

Clinicopathological and molecular features of SF3B1-mutated myeloproliferative neoplasms.

A. Iafrate, W. Wong, D. Dias-Santagata, 2019, Human pathology.

β-Catenin mutation status and outcomes in sporadic desmoid tumors.

Andrew, A. Iafrate, B. Yeap, 2013, The oncologist.

Durable Clinical Response to Entrectinib in NTRK1-Rearranged Non-Small Cell Lung Cancer

Manish B. Patel, A. Iafrate, A. Drilon, 2015, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

Identification of insertions in PTEN and TP53 in anaplastic thyroid carcinoma with angiogenic brain metastasis.

D. Dias-Santagata, L. Le, Zongli Zheng, 2015, Endocrine-related cancer.

Targeted Informatics for Optimal Detection, Characterization, and Quantification of FLT3 Internal Tandem Duplications Across Multiple Next-Generation Sequencing Platforms

Annette S. Kim, Danielle K. Manning, L. Le, 2020, The Journal of Molecular Diagnostics : JMD.

Cytomorphologic characteristics of next-generation sequencing-positive bile duct brushing specimens.

A. Iafrate, L. Le, J. Dudley, 2020, Journal of the American Society of Cytopathology.

Targeted Informatics for Optimal Detection, Characterization, and Quantification of FLT3 Internal Tandem Duplications Across Multiple Next-Generation Sequencing Platforms

Annette S. Kim, Danielle K. Manning, L. Le, 2020, The Journal of molecular diagnostics : JMD.

Morphologic Overlap Between Inflammatory Myofibroblastic Tumor and IgG4-related Disease: Lessons From Next-generation Sequencing

L. Le, V. Deshpande, I. Chebib, 2018, The American journal of surgical pathology.

Feasibility of Ultra-High-Throughput Functional Screening of Melanoma Biopsies for Discovery of Novel Cancer Drug Combinations

Adam A. Friedman, D. Neuberg, L. Trippa, 2017, Clinical Cancer Research.

Microcystic Adnexal Carcinoma Versus Desmoplastic Trichoepithelioma: A Comparative Study

L. Le, M. Hoang, A. Nguyen, 2013, The American Journal of dermatopathology.

Next‐generation sequencing adds value to the preoperative diagnosis of pancreatic cysts

A. Iafrate, L. Le, J. Dudley, 2017, Cancer cytopathology.

FLT3 inhibitor-induced neutrophilic dermatosis.

L. Le, M. Levis, A. Fathi, 2013, Blood.

Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer

Lauren L. Ritterhouse, G. Getz, S. Digumarthy, 2016 .

Molecular Mechanisms of Resistance to First- and Second-Generation ALK Inhibitors in ALK-Rearranged Lung Cancer.

Lauren L. Ritterhouse, G. Getz, S. Digumarthy, 2016, Cancer discovery.

Case records of the Massachusetts General Hospital. Case 24-2014. A 27-year-old man with severe osteoporosis and multiple bone fractures.

L. Le, A. Lin, M. Mannstadt, 2014, The New England journal of medicine.

Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.

G. Getz, A. Iafrate, J. Engelman, 2016, The New England journal of medicine.

Detection of Dual IDH 1 and IDH 2 Mutations by Targeted Next-Generation Sequencing in Acute

Mia Y. Platt, A. Iafrate, S. Yip, 2015 .

Malignant Neurocristic Hamartoma: A Tumor Distinct From Conventional Melanoma and Malignant Blue Nevus

M. Mihm, D. Dias-Santagata, L. Le, 2011, The American journal of surgical pathology.

MDM2 oncogene as a target for cancer therapy: An antisense approach.

L. Le, S. Agrawal, H. Wang, 1999, International journal of oncology.

Clinicopathologic Features of Non-Small-Cell Lung Cancer Harboring an NTRK Gene Fusion.

A. Iafrate, A. Drilon, M. Mino‐Kenudson, 2017, JCO precision oncology.

Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma.

Rebecca A Betensky, Matija Snuderl, David N Louis, 2011, Cancer cell.

Genotyping Cancer-Associated Genes in Chordoma Identifies Mutations in Oncogenes and Areas of Chromosomal Loss Involving CDKN2A, PTEN, and SMARCB1

L. Garraway, A. Iafrate, L. Macconaill, 2014, PloS one.

Germline mutations in oncogene-induced senescence pathways are associated with multiple sessile serrated adenomas.

L. Le, N. Bardeesy, D. Chung, 2014, Gastroenterology.

Molecular classification of MYC-driven B-cell lymphomas by targeted gene expression profiling of fixed biopsy specimens.

S. Monti, D. Neuberg, P. D. Dal Cin, 2015, The Journal of molecular diagnostics : JMD.

KIF13B-NRG1 Gene Fusion and KRAS Amplification in a Case of Natural Progression of Lung Cancer

A. Iafrate, L. Le, J. Lennerz, 2017, International journal of surgical pathology.

Acquired Resistance to Crizotinib in NSCLC with MET Exon 14 Skipping

Jeffrey W. Clark, L. Sequist, J. Engelman, 2016, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.

MET Exon 14 Skipping in Non-Small Cell Lung Cancer.

Martin J. Aryee, Zhongming Zhao, A. Iafrate, 2016, The oncologist.

Analytical Validation of the Next-Generation Sequencing Assay for a Nationwide Signal-Finding Clinical Trial: Molecular Analysis for Therapy Choice Clinical Trial.

Lisa M McShane, Robin D Harrington, Chih-Jian Lih, 2017, The Journal of molecular diagnostics : JMD.

Design of a Genomics Curriculum: Competencies for Practicing Pathologists.

L. Le, S. Boyd, K. Voelkerding, 2015, Archives of pathology & laboratory medicine.

Impact of EML4-ALK Variant on Resistance Mechanisms and Clinical Outcomes in ALK-Positive Lung Cancer.

A. Iafrate, P. Stephens, A. Shaw, 2018, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Crizotinib in ROS 1-Rearranged Non – Small-Cell Lung Cancer

Jeffrey W. Clark, A. Iafrate, A. Shaw, 2014 .

Clinical Validation of a Cell-Free DNA Gene Panel.

Julie M. Batten, A. Iafrate, P. Brastianos, 2019, The Journal of molecular diagnostics : JMD.

Clinical Utility of Rapid EGFR Genotyping in Advanced Lung Cancer

Julie M. Batten, S. Digumarthy, A. Iafrate, 2018, JCO precision oncology.

Next-Generation Sequencing and Fluorescence in Situ Hybridization Have Comparable Performance Characteristics in the Analysis of Pancreaticobiliary Brushings for Malignancy.

Thomas O. McDonald, Julie M. Batten, A. Iafrate, 2016, The Journal of molecular diagnostics : JMD.

Impact of next-generation sequencing on the clinical diagnosis of pancreatic cysts.

A. Iafrate, M. Mino‐Kenudson, D. Dias-Santagata, 2016, Gastrointestinal endoscopy.

Artificial Intelligence Approach for Variant Reporting

Jochen K. Lennerz, Maciej Pacula, Michael G. Zomnir, 2018, JCO clinical cancer informatics.

Clinical and radiographic response following targeting of BCAN-NTRK1 fusion in glioneuronal tumor

A. Iafrate, D. Cahill, P. Brastianos, 2017, npj Precision Oncology.

EZH2 Codon 641 Mutations are Common in BCL2-Rearranged Germinal Center B Cell Lymphomas

N. Harris, A. Iafrate, B. Bernstein, 2011, PloS one.

Recurrent Chromosomal Copy Number Alterations in Sporadic Chordomas

Julie M. Batten, R. Xavier, A. Iafrate, 2011, PloS one.

Novel and established EWSR1 gene fusions and associations identified by next generation sequencing and fluorescence in-situ hybridization.

A. Iafrate, M. Rivera, D. Dias-Santagata, 2019, Human pathology.

Aleukemic cutaneous myeloid sarcoma

L. Le, S. Kraft, R. Nazarian, 2013, Journal of cutaneous pathology.

Diffuse large B-cell lymphoma with concurrent high MYC and BCL2 expression shows evidence of active B-cell receptor signaling by quantitative immunofluorescence

L. Le, A. Bogusz, Richard H. G. Baxter, 2017, PloS one.

Colorectal cancer in Crohn’s colitis is comparable to sporadic colorectal cancer

Julie M. Batten, D. Park, A. Iafrate, 2016, International Journal of Colorectal Disease.

Recurrent PROC and novel PROS1 mutations in Vietnamese patients diagnosed with idiopathic deep venous thrombosis

L. Le, H. A. Vu, M. D. Do, 2020, International journal of laboratory hematology.

MET Amplification in Esophageal Squamous Carcinoma

A. Iafrate, L. Le, J. Lennerz, 2018, International journal of surgical pathology.

Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor-Positive Breast Cancer.

Maristela L Onozato, A. Iafrate, M. Onozato, 2017, Cancer discovery.

A Nanopore Sequencing-Based Assay for Rapid Detection of Gene Fusions.

A. Iafrate, L. Le, W. Jeck, 2019, The Journal of molecular diagnostics : JMD.

Acinar Cystadenoma of the Pancreas: A Clinicopathologic Study of 10 Cases Including Multilocular Lesions With Mural Nodules

K. Badizadegan, L. Le, V. Deshpande, 2012, The American journal of surgical pathology.

Inactivation of the tumor suppressor WTX in a subset of pediatric tumors

A. Iafrate, M. Rivera, Yunqing Ma, 2014, Genes, chromosomes & cancer.

Identification of oncogenic mutations and gene fusions in the follicular variant of papillary thyroid carcinoma.

Samuel E. Donovan, A. Iafrate, D. Dias-Santagata, 2014, The Journal of clinical endocrinology and metabolism.

Digital media archive for gross pathology images based on open-source tools and Fast Healthcare Interoperability Resources (FHIR)

L. Le, Emilio Madrigal, 2021, Modern Pathology.

t(4;12)(q12;p13) ETV6-rearranged AML without eosinophilia does not involve PDGFRA: relevance for imatinib insensitivity

A. Iafrate, P. D. Dal Cin, D. Dias-Santagata, 2021, Blood advances.