S. Altman

发表

Aptamers against pathogenic microorganisms

A. Davydova, M. Vorobjeva, D. Pyshnyi, 2015, Critical reviews in microbiology.

The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme

N. Pace, T. Marsh, S. Altman, 1983, Cell.

A view of RNase P.

S. Altman, 2007, Molecular bioSystems.

RNase P cleaves the adenine riboswitch and stabilizes pbuE mRNA in Bacillus subtilis.

S. Altman, E. Seif, 2008, RNA.

Novel reactions of RNAase P with a tRNA-like structure in turnip yellow mosaic virus RNA

S. Altman, C. Guerrier-Takada, A. Belkum, 1988, Cell.

Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity

Alexander V. Tyakht, S. Altman, M. Dubina, 2017, Proceedings of the National Academy of Sciences.

RNA therapeutics: beyond RNA interference and antisense oligonucleotides

A. Krainer, S. Altman, R. Kole, 2012, Nature Reviews Drug Discovery.

Twenty years

S. Altman, 2015, RNA.

Coordinate inhibition of expression of several genes for protein subunits of human nuclear RNase P

S. Altman, E. Kovrigina, D. Wesolowski, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Peptide Conjugated Morpholinos for Management of The Huanglongbing Pathosystem.

S. Altman, W. Hunter, A. Sandoval-Mojica, 2020, Pest management science.

Properties of purified ribonuclease P from Escherichia coli.

S. Altman, R. Kole, 1981, Biochemistry.

Analysis of the functional role of conserved residues in the protein subunit of ribonuclease P from Escherichia coli.

D. Landsman, S. Altman, A. Baxevanis, 1997, Journal of molecular biology.

Requirements for cleavage by a modified RNase P of a small model substrate.

S. Altman, F. Liu, F. Liu, 1996, Nucleic acids research.

E. coli RNAase P has a required RNA component in vivo

S. Altman, R. Kole, B. Stark, 1980, Cell.

Aspects of biochemical catalysis

S. Altman, 1984, Cell.

Reconstitution of RNAase P activity using inactive subunits from E. coli and HeLa cells

S. Altman, H. Gold, 1986, Cell.

Selection and characterization of randomly produced mutants in the gene coding for M1 RNA.

S. Altman, N. Lumelsky, S. Altman, 1988, Journal of molecular biology.

Site-specific cleavage by metal ion cofactors and inhibitors of M1 RNA, the catalytic subunit of RNase P from Escherichia coli.

S. Altman, S. Kazakov, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Important 2'-hydroxyl groups in model substrates for M1 RNA, the catalytic RNA subunit of RNase P from Escherichia coli.

S. Altman, J. Perreault, S. Altman, 1992, Journal of molecular biology.

RNA enzyme-directed gene therapy.

S. Altman, S. Altman, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide sequences of the RNA subunit of RNase P from several mammals.

S. Altman, R. S. Puranam, D. Wesolowski, 1993, Genomics.

Large deletion mutants of Escherichia coli tRNATyr1.

S. Altman, G. McCorkle, G. McCORKLE, 1982, Journal of molecular biology.

Purification and characterization of Rpp25, an RNA-binding protein subunit of human ribonuclease P.

S. Altman, C. Guerrier-Takada, V. Gopalan, 2002, RNA.

Protein-RNA interactions in the subunits of human nuclear RNase P.

S. Altman, C. Guerrier-Takada, T. Jiang, 2001, RNA.

Separation of E. coli tRNA-Tyr precursor RNA from E. coli tRNA by hydroxyapatite chromatography.

S. Altman, B. Stark, 1974, Analytical biochemistry.

Identification of tRNA precursor molecules made by phage T4.

B. Barrell, J. Seidman, S. Altman, 1973, Nature: New biology.

Function and subnuclear distribution of Rpp21, a protein subunit of the human ribonucleoprotein ribonuclease P.

S. Altman, C. Guerrier-Takada, N. Jarrous, 2001, RNA.

An E. coli gene coding for a protamine-like protein

S. Altman, P. Model, G. Dixon, 1981, Cell.

In vitro processing of B. mori transfer RNA precursor molecules

S. Altman, R. Garber, 1979, Cell.

Inactivation of gene expression using ribonuclease P and external guide sequences.

S. Altman, C. Guerrier-Takada, 2000, Methods in enzymology.

Novel Peptide Conjugates of Modified Oligonucleotides for Inhibition of Bacterial RNase P

A. Davydova, D. Pyshnyi, S. Altman, 2019, Front. Pharmacol..

[Modified Oligonucleotides for Guiding RNA Cleavage Using Bacterial RNase P].

A. Davydova, M. Vorobjeva, D. Pyshnyi, 2018, Molekuliarnaia biologiia.

Modified Oligonucleotides for Guiding RNA Cleavage Using Bacterial RNase P

A. Davydova, M. Vorobjeva, D. Pyshnyi, 2018, Molecular Biology.

An Open Letter to Elias Zerhouni

Jeffrey W. Roberts, N. Cozzarelli, C. Yanofsky, 2005, Science.

Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells

I. V. Chernikov, D. Pyshnyi, S. Altman, 2021, Molecular therapy. Nucleic acids.

My Life in Science

S. Altman, 2001, Nature Medicine.

Reconstitution of RNase P activity from inactive RNA and protein.

S. Altman, R. Kole, 1979, Proceedings of the National Academy of Sciences of the United States of America.

A noncoding RNA in Saccharomyces cerevisiae is an RNase P substrate.

S. Altman, Li Yang, 2007, RNA.

M1 RNA with large terminal deletions retains its catalytic activity

S. Altman, C. Guerrier-Takada, 1986, Cell.

Ribonuclease P. Postscript.

S. Altman, 1990, The Journal of biological chemistry.

Targeted cleavage of mRNA by human RNase P.

S. Altman, E. Hwang, Y. Yuan, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Enzymatic Cleavage of RNA by RNA (Nobel Lecture)

S. Altman, 1990 .

Inhibition of viral gene expression by the catalytic RNA subunit of RNase P from Escherichia coli.

S. Altman, F. Liu, F. Liu, 1995, Genes & development.

Multiple binding modes of substrate to the catalytic RNA subunit of RNase P from Escherichia coli.

D. P. Pomeranz Krummel, S. Altman, 1999, RNA.

A physical assay for and kinetic analysis of the interactions between M1 RNA and tRNA precursor substrates.

S. Altman, C. Guerrier-Takada, 1993, Biochemistry.

M1 RNA, the RNA subunit of Escherichia coli ribonuclease P, can undergo a pH-sensitive conformational change.

S. Altman, C. Guerrier-Takada, 1986, Biochemistry.

Identification of a ribonuclease P-like activity from human KB cells

R. Koski, S. Altman, A. Bothwell, 1976, Cell.

Partial purification and properties of an endoribonuclease isolated from human KB cells.

S. Altman, A. Bothwell, 1975, The Journal of biological chemistry.

Isolation of tyrosine tRNA precursor molecules.

S. Altman, 1971, Nature: New biology.

Tightly Regulated Gene Expression System in Salmonella enterica Serovar Typhimurium

S. Altman, C. Guerrier-Takada, J. Galán, 2002, Journal of bacteriology.

Inhibition of expression of virulence genes of Yersinia pestis in Escherichia coli by external guide sequences and RNase P.

S. Altman, M. Izadjoo, J. Ko, 2008, RNA.

Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency.

S. Altman, V. Vlassov, A. Fokina, 2020, Proceedings of the National Academy of Sciences of the United States of America.

Kinetics and intermediates in the intracellular synthesis of bacteriophage T4 deoxyribonucleic acid.

S. Altman, L. Lerman, 1970, Journal of molecular biology.

Inactivation of expression of several genes in a variety of bacterial species by EGS technology

S. Altman, G. Shan, N. Shen, 2009, Proceedings of the National Academy of Sciences.

Biosynthesis of transfer RNA in Escherichia coli

S. Altman, 1975, Cell.

Antibodies in human serum that precipitate ribonuclease P.

S. Altman, J. Craft, J. Hardin, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Evidence for preferential breakage of the minus strand of phi-X174 replicative form DNA by a T4-induced endonuclease.

S. Altman, D. Denhardt, 1970, Biochimica et biophysica acta.

Multiple cis-acting elements are required for RNA polymerase III transcription of the gene encoding H1 RNA, the RNA component of human RNase P.

G. Hannon, T. Nilsen, S. Altman, 1991, The Journal of biological chemistry.

Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties

S. Altman, V. Vlassov, A. Fokina, 2019, Proceedings of the National Academy of Sciences.

Tyrosine tRNA precursor molecule polynucleotide sequence.

S. Altman, J. Smith, Sidney Altman, 1971, Nature: New biology.

A specific endoribonuclease, RNase P, affects gene expression of polycistronic operon mRNAs

S. Altman, Yong Li, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Model substrates for an RNA enzyme.

S. Altman, C. Guerrier-Takada, W. McClain, 1987, Science.

Ribonuclease P: an enzyme with an essential RNA component.

R Kole, S. Altman, R. Kole, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Purification and properties of a specific Escherichia coli ribonuclease which cleaves a tyrosine transfer ribonucleic acid presursor.

S. Altman, J. Smith, H. Robertson, 1972, The Journal of biological chemistry.

TRANSFER RNA PROCESSING AND GENE REGULATION

S. Altman, R. Reed, C. Guerrier-Takada, 1982 .

Ribonuclease P

S. Altman, 2011, Philosophical Transactions of the Royal Society B: Biological Sciences.

External guide sequences for an RNA enzyme.

S. Altman, A. C. Forster, 1990, Science.

Mapping RNA-protein interactions in ribonuclease P from Escherichia coli using electron paramagnetic resonance spectroscopy.

S. Altman, H. Kühne, G. Brudvig, 1999, Biochemistry.

Transfer RNA: Structure, properties, and recognition. Monograph 9A P. Schimmel, D. Söll and J. Abelson, eds. New York: Cold Spring Harbor Laboratory. 624 pp. $60.00

S. Altman, 1980, Cell.

Ribonuclease P as a snRNP

S. Altman, H. Gold, M. Bartkiewicz, 1988 .

Modified Oligonucleotides for Guiding RNA Cleavage Using Bacterial RNase P

A. Davydova, M. Vorobjeva, D. Pyshnyi, 2018, Molecular Biology.

Targeted cleavage of mRNA in vitro by RNase P from Escherichia coli.

S. Altman, C. Guerrier-Takada, Y. Li, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Structure and transcription of a human gene for H1 RNA, the RNA component of human RNase P

M. Baer, T. W. Nilsen, C. Costigan, 1990, Nucleic Acids Res..

Inhibition of the expression of the human RNase P protein subunits Rpp21, Rpp25, Rpp29 by external guide sequences (EGSs) and siRNA.

S. Altman, Haifeng Zhang, 2004, Journal of molecular biology.

Autoantigenic properties of some protein subunits of catalytically active complexes of human ribonuclease P.

S. Altman, C. Guerrier-Takada, C. Hoog, 1998, RNA.

Characterization of an RNase P activity from HeLa cell mitochondria. Comparison with the cytosol RNase P activity.

S. Altman, C. Guerrier-Takada, G. Attardi, 1985, The Journal of biological chemistry.

In search of RNase P RNA from microbial genomes.

S. Altman, Yong Li, 2004, RNA.

Characterization of two scleroderma autoimmune antigens that copurify with human ribonuclease P.

V. Štolc, S. Altman, P. Eder, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Varieties of RNase P: a nomenclature problem?

S. Altman, V. Gopalan, A. Vioque, 2000, RNA.

Rpp1, an essential protein subunit of nuclear RNase P required for processing of precursor tRNA and 35S precursor rRNA in Saccharomyces cerevisiae.

V. Štolc, S. Altman, 1997, Genes & development.

S. Altman, A. C. Forster, 1990, Cell.

Recent studies of ribonuclease P

S. Altman, S. Talbot, L. Kirsebom, 1993, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Partial reconstitution of human RNase P in HeLa cells between its RNA subunit with an affinity tag and the intact protein components.

S. Altman, Yong Li, 2002, Nucleic acids research.

A protein subunit of human RNase P, Rpp14, and its interacting partner, OIP2, have 3′→5′ exoribonuclease activity

S. Altman, T. Jiang, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Protein-protein interactions with subunits of human nuclear RNase P.

S. Altman, T. Jiang, Sidney Altman, 2001, Proceedings of the National Academy of Sciences of the United States of America.

A subunit of human nuclear RNase P has ATPase activity.

S. Altman, Y. Li, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Human ribonuclease P.

S. Altman, N. Jarrous, 2001, Methods in enzymology.

Localization in the Nucleolus and Coiled Bodies of Protein Subunits of the Ribonucleoprotein Ribonuclease P

S. Altman, J. Wolenski, N. Jarrous, 1999, The Journal of cell biology.

Rpp14 and Rpp29, two protein subunits of human ribonuclease P.

S. Altman, N. Jarrous, P. Eder, 1999, RNA.

Artificial regulation of gene expression in Escherichia coli by RNase P.

S. Altman, C. Guerrier-Takada, Y. Li, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Identification and characterization of an RNA molecule that copurifies with RNase P activity from HeLa cells.

S. Altman, H. Gold, M. Bartkiewicz, 1989, Genes & development.

Rpp2, an essential protein subunit of nuclear RNase P, is required for processing of precursor tRNAs and 35S precursor rRNA in Saccharomyces cerevisiae.

V. Štolc, S. Altman, A. Katz, 1998, Proceedings of the National Academy of Sciences of the United States of America.

The RNA Subunit of Ribonuclease P from the Zebrafish, Danio rerio*

Ashok Srinivasan, M. Fishman, S. Altman, 1996, The Journal of Biological Chemistry.

An immunological determinant of RNase P protein is conserved between Escherichia coli and humans.

S. Altman, M. Mamula, J. Craft, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Nucleotide sequence of the gene encoding the RNA subunit (M1 RNA) of ribonuclease P from Escherichia coli

Sidney Altman, S. Altman, C. Guerrier-Takada, 1982, Cell.

Structure and Function of Bacterial RNase P

S. Altman, C. Guerrier-Takada, N. Lumelsky, 1989 .

Effective inhibition of influenza virus production in cultured cells by external guide sequences and ribonuclease P.

S. Altman, D. Plehn-Dujowich, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Biosynthesis of Transfer RN

S. Altman, V. Daniel, 1981 .

The RNA-Protein World.

S. Altman, 2013, RNA.

Identification and Functional Analysis of the Primary Pantothenate Transporter, PfPAT, of the Human Malaria Parasite Plasmodium falciparum*

Choukri Ben Mamoun, S. Altman, Niseema D. Pachikara, 2013, The Journal of Biological Chemistry.

Ribonuclease P: an enzyme with a catalytic RNA subunit.

S. Altman, S. Altman, 1989, Advances in enzymology and related areas of molecular biology.

Nucleotide modification in vitro of the precursor of transfer RNA of Escherichia coli.

D. Söll, S. Altman, K. P. Schaefer, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Identification of an ochre-suppressing anticodon.

S. Brenner, S. Altman, J. Smith, 1971, Journal of molecular biology.

Liquid drop of DNA libraries reveals total genome information

S. Altman, K. Severinov, S. Terekhov, 2020, Proceedings of the National Academy of Sciences.

Inhibition of gene expression by RNase P.

S. Altman, E. W. Lundblad, 2010, New biotechnology.

Characterization of RNase P from Thermotoga maritima.

S. Altman, D. Lazarev, R. Paul, 2001, Nucleic acids research.

The origin of life, “the World of RNA,” and the problem of antibiotic resistance

Sidney Altman, S. Altman, 2017, Herald of the Russian Academy of Sciences.

Masters of DNA

S. Altman, 2005, Journal of Biological Chemistry.

Substrate recognition by human RNase P: identification of small, model substrates for the enzyme.

S. Altman, Y. Yuan, 1995, The EMBO journal.

RNA precursor molecules and ribonucleases in E. coli

S. Altman, H. Robertson, 1973, Molecular and Cellular Biochemistry.

Enzymatic cleavage of RNA by RNA

Sidney Altman, S. Altman, 1986 .

RNA-processing Nucleases

S. Altman, C. Guerrier-Takada, H. Robertson, 1982 .

Ultrahigh-throughput functional profiling of microbiota communities

S. Altman, K. Severinov, A. Samoilov, 2018, Proceedings of the National Academy of Sciences.

Regulated expression of functional external guide sequences in mammalian cells using a U6 RNA polymerase III promoter.

S. Altman, E. Kovrigina, Li Yang, 2005, RNA.

A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding

B. Turk, S. Altman, G. Bourenkov, 2020, Science Advances.

A peptide-morpholino oligomer conjugate targeting Staphylococcus aureus gyrA mRNA improves healing in an infected mouse cutaneous wound model.

Sidney Altman, Alexander Stojadinovic, S. Altman, 2013, International journal of pharmaceutics.

Effects of 9-aminoacridine on bacteriophage T4 deoxyribonucleic acid synthesis.

S. Altman, L. Lerman, 1970, Journal of Molecular Biology.

9-Aminoacridine mutagenesis of bacteriophage T4 intracellular DNA

S. Altman, V. Warner, 1975, Molecular and General Genetics MGG.

A T4-induced endonuclease which attacks T4 DNA.

S. Altman, M. Meselson, 1970, Proceedings of the National Academy of Sciences of the United States of America.

Evidence for helical unwinding of an RNA substrate by the RNA enzyme RNase P: use of an interstrand disulfide crosslink in substrate.

D. P. Pomeranz Krummel, O. Kent, S. Altman, 2000, Journal of molecular biology.

Transfer RNA processing enzymes

S. Altman, 1981, Cell.

Specific interactions in RNA enzyme-substrate complexes.

S. Altman, C. Guerrier-Takada, N. Lumelsky, 1989, Science.

Elucidation of structure-function relationships in the protein subunit of bacterial RNase P using a genetic complementation approach.

S. Altman, V. Gopalan, M. Jovanović, 2002, Nucleic acids research.

Context effects on nonsense codon suppression in Escherichia coli.

S. Altman, S. Feinstein, Sheldon I. Feinstein, 1978, Genetics.

The road to RNase P

S. Altman, 2000, Nature Structural Biology.

Role in translation of a triple tandemly repeated sequence in the 5'-untranslated region of human thymidylate synthase mRNA.

S. Altman, T. Seno, D. Ayusawa, 1987, Nucleic acids research.

Metal ion requirements and other aspects of the reaction catalyzed by M1 RNA, the RNA subunit of ribonuclease P from Escherichia coli.

S. Altman, C. Guerrier-Takada, L. C. Allen, 1986, Biochemistry.

Disruption of type III secretion in Salmonella enterica serovar Typhimurium by external guide sequences.

S. Altman, Haifeng Zhang, J. Galán, 2004, Nucleic acids research.

Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum

Choukri Ben Mamoun, S. Altman, D. Wesolowski, 2012, Proceedings of the National Academy of Sciences.

Kinetics of the processing of the precursor to 4.5 S RNA, a naturally occurring substrate for RNase P from Escherichia coli.

S. Altman, K. Peck-Miller, S. Altman, 1991, Journal of molecular biology.

RNase P cleaves transient structures in some riboswitches.

S. Altman, C. Guerrier-Takada, D. Wesolowski, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Catalytic activity of an RNA molecule prepared by transcription in vitro.

S. Altman, C. Guerrier-Takada, S Altman, 1984, Science.

Basic peptide-morpholino oligomer conjugate that is very effective in killing bacteria by gene-specific and nonspecific modes

Sidney Altman, S. Altman, Neeru Gandotra, 2011, Proceedings of the National Academy of Sciences.

Human RNase P ribonucleoprotein is required for formation of initiation complexes of RNA polymerase III

S. Altman, N. Jarrous, D. Wesolowski, 2015, Nucleic acids research.

Coding properties of an ochre-suppressing derivative of Escherichia coli tRNAITyr.

S. Altman, S. Feinstein, 1977, Journal of molecular biology.

Endoribonuclease activity associated with animal RNA viruses

S. Altman, D. Kolakofsky, 1978, Journal of virology.

Inhibition of Escherichia coli viability by external guide sequences complementary to two essential genes

S. Altman, C. Guerrier-Takada, D. Wesolowski, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Protein-RNA interactions in the RNase P holoenzyme from Escherichia coli.

S. Altman, A. Vioque, J. Arnez, 1988, Journal of molecular biology.

Veal heart ribonuclease P has an essential RNA component.

S. Altman, C. Guerrier-Takada, E. Akaboshi, 1980, Biochemical and biophysical research communications.

Differential effects of mutations in the protein and RNA moieties of RNase P on the efficiency of suppression by various tRNA suppressors.

S. Altman, L. Kirsebom, M. Baer, 1988, Journal of molecular biology.

Structure in solution of M1 RNA, the catalytic subunit of ribonuclease P from Escherichia coli.

S. Altman, C. Guerrier-Takada, S Altman, 1984, Biochemistry.

14 tRNA Processing Enzymes from Escherichia coli

S. Altman, R. Kole, 1982 .

RNA binding properties of conserved protein subunits of human RNase P

S. Altman, N. Jarrous, D. Wesolowski, 2011, Nucleic acids research.

Mapping RNA-protein interactions in ribonuclease P from Escherichia coli using disulfide-linked EDTA-Fe.

S. Altman, V. Gopalan, R. Fox, 2000, Journal of molecular biology.

Verification of phylogenetic predictions in vivo and the importance of the tetraloop motif in a catalytic RNA.

D. P. Pomeranz Krummel, S. Altman, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Gel retardation analysis of the interaction between C5 protein and M1 RNA in the formation of the ribonuclease P holoenzyme from Escherichia coli.

S. Altman, S. Talbot, S. Altman, 1994, Biochemistry.

Nucleotide sequence and in vitro processing of a precursor molecule to Escherichia coli 4.5 S RNA.

S. Altman, A. Bothwell, R. Garber, 1976, The Journal of biological chemistry.

History of RNase P and Overview of Its Catalytic Activity

S. Altman, 2010 .

Site-directed mutagenesis of M1 RNA, the RNA subunit of Escherichia coli ribonuclease P. The effects of an addition and small deletions on catalytic function.

S. Altman, N. Lawrence, 1986, Journal of molecular biology.

Preparation and characterization of RNase P from Escherichia coli.

S. Altman, C. Guerrier-Takada, A. Vioque, 1990, Methods in enzymology.

Reaction in vitro of some mutants of RNase P with wild-type and temperature-sensitive substrates.

S. Altman, L. Kirsebom, 1989, Journal of molecular biology.

Kinetic and thermodynamic analysis of RNA-protein interactions in the RNase P holoenzyme from Escherichia coli.

S. Altman, S. Talbot, S. Altman, 1994, Biochemistry.

Cleavage of tRNA precursors by the RNA subunit of E. coli ribonuclease P (M1 RNA) is influenced by 3′-proximal CCA in the substrates

S. Altman, C. Guerrier-Takada, W. McClain, 1984, Cell.

Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine

S. Brenner, S. Altman, 2002, Nature Medicine.

RNase P: Variations and Uses*

S. Altman, V. Gopalan, A. Vioque, 2002, The Journal of Biological Chemistry.

Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum

Choukri Ben Mamoun, S. Altman, Aprajita Garg, 2015, Proceedings of the National Academy of Sciences.

Characterization of RNA with unusual electrophoretic mobility from tissues of patients with Crohn's disease

A. West, S. Altman, U. Lundberg, 1995, FEBS letters.

6.08 – RNA Enzymes: Overview

S. Altman, 1999 .

Fluorescence properties of a tryptophan residue in an aromatic core of the protein subunit of ribonuclease P from Escherichia coli.

A. Fersht, S. Altman, G. Schreiber, 1997, Journal of molecular biology.

A catalytic RNA and its gene from Salmonella typhimurium.

S. Altman, M. Baer, S. Altman, 1985, Science.

Nobel lecture. Enzymatic cleavage of RNA by RNA.

S. Altman, 1990, Bioscience reports.

Recent Studies of RNase P

S. Altman, S. Talbot, L. Kirsebom, 1995 .

Selection of guide sequences that direct efficient cleavage of mRNA by human ribonuclease P.

S. Altman, Y. Yuan, S. Altman, 1994, Science.

Inactivation of expression of two genes in Saccharomyces cerevisiae with the external guide sequence methodology.

S. Altman, Xudong Cheng, J. Ko, 2011, RNA.

Catalysis by the RNA subunit of RNase P--a minireview.

S. Altman, C. Guerrier-Takada, N. Lumelsky, 1989, Gene.

Three-dimensional working model of M1 RNA, the catalytic RNA subunit of ribonuclease P from Escherichia coli.

E. Westhof, S. Altman, S. Altman, 1994, Proceedings of the National Academy of Sciences of the United States of America.

A trinucleotide can promote metal ion-dependent specific cleavage of RNA.

S. Altman, S. Kazakov, 1992, Proceedings of the National Academy of Sciences of the United States of America.

MicroRNAs: From Basic Science to Disease Biology

Sidney Altman, Victor R. Ambros, Krishnarao Appasani, 2009 .

The effect of a single, temperature-sensitive mutation on global gene expression in Escherichia coli.

S. Altman, Kyle Cole, Yong Li, 2003, RNA.

Processing of the precursor to the catalytic RNA subunit of RNase P from Escherichia coli.

S. Altman, U. Lundberg, 1995, RNA: A publication of the RNA Society.

Combined effect of a peptide–morpholino oligonucleotide conjugate and a cell-penetrating peptide as an antibiotic

Sidney Altman, S. Altman, Donna Wesolowski, 2013, Proceedings of the National Academy of Sciences.

Affinity chromatography with an immobilized RNA enzyme.

S. Altman, S Altman, A Vioque, 1986, Proceedings of the National Academy of Sciences of the United States of America.

The recognition by RNase P of precursor tRNAs.

S. Altman, U. RajBhandary, R. Reilly, 1988, Journal of Biological Chemistry.

Characterization in vitro of the defect in a temperature-sensitive mutant of the protein subunit of RNase P from Escherichia coli

S. Altman, D. Wesolowski, M. Baer, 1989, Journal of bacteriology.

Polarity effects in the lactose operon of Escherichia coli.

S. Altman, Yong Li, 2004, Journal of molecular biology.

Ultrahigh-throughput functional profiling of microbiota communities

S. Altman, K. Severinov, A. Samoilov, 2018, Proceedings of the National Academy of Sciences.

9 – Ribonuclease P

S. Altman, A. Vioque, 2001 .

1 – Cleavage of RNA by RNase P from Escherichia coli

S. Altman, C. Guerrier-Takada, N. Lumelsky, 1987 .

Differential evolution of substrates for an RNA enzyme in the presence and absence of its protein cofactor

S. Altman, Fenyong Liu, 1994, Cell.

The protein cofactor allows the sequence of an RNase P ribozyme to diversify by maintaining the catalytically active structure of the enzyme.

J. Kim, S. Altman, A. Kilani, 1997, RNA.

Mapping in three dimensions of regions in a catalytic RNA protected from attack by an Fe(II)-EDTA reagent.

E. Westhof, S. Altman, D. Wesolowski, 1996, Journal of molecular biology.

Reconstitution of enzymatic activity from fragments of M1 RNA.

S. Altman, C. Guerrier-Takada, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Protection from chemical modification of nucleotides in complexes of M1 RNA, the catalytic subunit of RNase P from E coli, and tRNA precursors.

S. Altman, D. Wesolowski, A. Knap, 1990, Biochimie.

Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum

Choukri Ben Mamoun, S. Altman, D. Wesolowski, 2012, Proceedings of the National Academy of Sciences.

Reconstitution of enzymatic activity from fragments of Ml RNA (RNA catalysis/RNA-RNA complementation/RNA-RNA interaction/RNase P)

S. Altman, C. Guerrier-Takada, 2016 .

A G43 to U43 mutation in E. coli tRNAtyrsu3+ which affects processing by RNase P.

S. Altman, C. Guerrier-Takada, P. Furdon, 1983, Nucleic acids research.

Identification of ribonuclease P activity from chick embryos.

S. Altman, E. J. Bowman, 1980, Biochimica et biophysica acta.

Aspects of RNase P Structure and Function

R. Koski, S. Altman, R. Kole, 1980 .

Characteristics of ribonuclease P from various organisms.

S. Altman, C. Guerrier-Takada, W. McClain, 1987, Cold Spring Harbor symposia on quantitative biology.

Rapid selection of accessible and cleavable sites in RNA by Escherichia coli RNase P and random external guide sequences

S. Altman, Gaoping Xiao, J. Ko, 2008, Proceedings of the National Academy of Sciences.

Common Courtesy

S. Altman, 1999, Science.

Catalysis by the RNA subunit of RNase P — a minireview**Presented at the Albany Conference on ‘RNA: Catalysis, Splicing, Evolution’, Rensselaerville, NY (U.S.A.) 22-25 September 1988.

S. Altman, C. Guerrier-Takada, N. Lumelsky, 1989 .

OLE RNA, an RNA motif that is highly conserved in several extremophilic bacteria, is a substrate for and can be regulated by RNase P RNA

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