Ka-Ho Leung

发表

A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag+ ions based on the exonuclease III-mediated digestion of C-Ag+-C DNA.

Modi Wang, Ka-Ho Leung, Sheng Lin, 2014, Journal of materials chemistry. B.

In silico screening of quadruplex-binding ligands.

Dik-Lung Ma, Daniel Shiu-Hin Chan, Chung-Hang Leung, 2012, Methods.

Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe† †Electronic supplementary information (ESI) available: Compound characterisation and supplementary data. See DOI: 10.1039/c4sc03319a Click here for additional data file.

Sheng Lin, Dik-Lung Ma, Chung-Hang Leung, 2014, Chemical science.

A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase

Hui Yang, Dik-Lung Ma, Daniel Shiu-Hin Chan, 2013 .

Structure-Based Approaches Targeting Oncogene Promoter G-Quadruplexes

Ka-Ho Leung, D. Chan, C. Leung, 2013 .

Pharmacophore modeling for the identification of small-molecule inhibitors of TACE.

Ka-Ho Leung, Sheng Lin, D. Chan, 2015, Methods.

Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening.

Modi Wang, Ka-Ho Leung, Sheng Lin, 2015, Methods.

Application of a DNA-based luminescence switch-on method for the detection of mercury(II) ions in water samples from Hong Kong

Ka-Ho Leung, D. Chan, C. Leung, 2012 .

An oligonucleotide-based switch-on luminescent probe for the detection of kanamycin in aqueous solution

Ka-Ho Leung, D. Chan, C. Leung, 2013 .

Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme.

Ka-Ho Leung, Sheng Lin, D. Chan, 2015, Methods.

Biological Applications of Supramolecular Coordination Complexes

Ka-Ho Leung, C. Leung, Dik‐Lung Ma, 2017 .

An oligonucleotide-based label-free luminescent switch-on probe for RNA detection utilizing a G-quadruplex-selective iridium(III) complex.

Ka-Ho Leung, D. Chan, C. Leung, 2014, Nanoscale.

Label-free luminescent switch-on detection of endonuclease IV activity using a G-quadruplex-selective iridium(III) complex.

Ka-Ho Leung, D. Chan, C. Leung, 2013, ACS applied materials & interfaces.

Detection of base excision repair enzyme activity using a luminescent G-quadruplex selective switch-on probe.

Ka-Ho Leung, D. Chan, C. Leung, 2013, Chemical communications.

Recent advances in luminescent heavy metal complexes for sensing

Ka-Ho Leung, D. Chan, C. Leung, 2012 .

Discovery of a natural product inhibitor targeting protein neddylation by structure-based virtual screening.

Dik-Lung Ma, Daniel Shiu-Hin Chan, Chung-Hang Leung, 2012, Biochimie.

Bioactive luminescent transition-metal complexes for biomedical applications.

Dik-Lung Ma, Daniel Shiu-Hin Chan, Chung-Hang Leung, 2013, Angewandte Chemie.

Epigenetic modulation by inorganic metal complexes

Ka-Ho Leung, C. Leung, Dik‐Lung Ma, 2016 .

Label-free luminescent oligonucleotide-based probes.

Ka-Ho Leung, D. Chan, C. Leung, 2013, Chemical Society reviews.

A luminescent G-quadruplex switch-on probe for the highly selective and tunable detection of cysteine and glutathione.

Ka-Ho Leung, D. Chan, C. Leung, 2013, Chemical communications.

A label-free G-quadruplex-based switch-on fluorescence assay for the selective detection of ATP.

Hui Yang, Dik-Lung Ma, Daniel Shiu-Hin Chan, 2012, The Analyst.

An iridium(iii)-based irreversible protein–protein interaction inhibitor of BRD4 as a potent anticancer agent† †Electronic supplementary information (ESI) available: Synthetic methods, characterization and biological assays details. See DOI: 10.1039/c5sc02321a Click here for additional data file.

Ka-Ho Leung, C. Leung, Dik‐Lung Ma, 2015, Chemical science.

Antagonizing STAT3 dimerization with a rhodium(III) complex.

Ka-Ho Leung, D. Chan, C. Leung, 2014, Angewandte Chemie.

Label-free sensing of pH and silver nanoparticles using an "OR" logic gate.

Ka-Ho Leung, D. Chan, C. Leung, 2012, Analytica chimica acta.

Structure-based design of flavone derivatives as c-myc oncogene down-regulators.

Dik-Lung Ma, Daniel Shiu-Hin Chan, Chung-Hang Leung, 2013, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

A highly sensitive G-quadruplex-based luminescent switch-on probe for the detection of polymerase 3'-5' proofreading activity.

Ka-Ho Leung, D. Chan, C. Leung, 2013, Methods.

Antagonism of mTOR Activity by a Kinetically Inert Rhodium(III) Complex.

Ka-Ho Leung, D. Chan, C. Leung, 2014, ChemPlusChem.

Label-free detection of sub-nanomolar lead(II) ions in aqueous solution using a metal-based luminescent switch-on probe.

Ka-Ho Leung, D. Chan, C. Leung, 2013, Biosensors & bioelectronics.

Determination of cell metabolite VEGF₁₆₅ and dynamic analysis of protein-DNA interactions by combination of microfluidic technique and luminescent switch-on probe.

Jin-Ming Lin, Sheng Lin, Dik-Lung Ma, 2016, Biosensors & bioelectronics.

Label-Free Luminescent Oligonucleotide-Based Probes

Ka-Ho Leung, D. Chan, C. Leung, 2013 .

Current advancements in Aβ luminescent probes and inhibitors of Aβ aggregation.

Ka-Ho Leung, D. Chan, C. Leung, 2012, Current Alzheimer research.

A highly selective G-quadruplex-based luminescent switch-on probe for the detection of nanomolar strontium(II) ions in sea water

Ka-Ho Leung, D. Chan, C. Leung, 2012 .

Development of an Aptamer-Based Sensing Platform for Metal Ions, Proteins, and Small Molecules through Terminal Deoxynucleotidyl Transferase Induced G-Quadruplex Formation.

Chao Yang, Dik-Lung Ma, Chung-Hang Leung, 2015, ACS applied materials & interfaces.

A colorimetric chemosensor for Cu2+ ion detection based on an iridium(III) complex

Modi Wang, Ka-Ho Leung, Sheng Lin, 2014, Scientific Reports.

Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe

Ka-Ho Leung, Sheng Lin, C. Leung, 2014, Chemical science.

Label-free luminescence switch-on detection of T4 polynucleotide kinase activity using a G-quadruplex-selective probe.

Wei Wang, Dik-Lung Ma, Daniel Shiu-Hin Chan, 2014, Chemical communications.

Label-free luminescent switch-on detection of endonuclease IV activity using a G-quadruplex-selective iridium(III) complex.

Ka-Ho Leung, D. Chan, C. Leung, 2013, ACS applied materials & interfaces.

A Label-Free Luminescent Switch-On Assay for ATP Using a G-Quadruplex-Selective Iridium(III) Complex

Modi Wang, Ka-Ho Leung, D. Chan, 2013, PloS one.

Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening.

Modi Wang, Ka-Ho Leung, Sheng Lin, 2015, Methods.

Discovery of deoxyvasicinone derivatives as inhibitors of NEDD8-activating enzyme.

Ka-Ho Leung, Sheng Lin, D. Chan, 2015, Methods.