Zhong-Chang Wang

发表

Design, synthesis, biological evaluation and molecular modeling of dihydropyrazole sulfonamide derivatives as potential COX-1/COX-2 inhibitors.

Zhong Chen, Zhong-Chang Wang, Xiao-qiang Yan, 2015, Bioorganic & medicinal chemistry letters.

Design and biological evaluation of novel hybrids of 1, 5-diarylpyrazole and Chrysin for selective COX-2 inhibition.

Zhong-Chang Wang, Hai‐Liang Zhu, Shen-Zhen Ren, 2018, Bioorganic & medicinal chemistry.

Synthesis, biological evaluation of novel 4,5-dihydro-2H-pyrazole 2-hydroxyphenyl derivatives as BRAF inhibitors.

Zhong-Chang Wang, Hai‐Liang Zhu, Yu-Shun Yang, 2012, Bioorganic & medicinal chemistry.

Identification of novel B‐RafV600E inhibitors employing FBDD strategy

Zhong-Chang Wang, Peng-Fei Wang, Hai‐Liang Zhu, 2017, Biochemical pharmacology.

Synthesis, biological evaluation, and molecular docking studies of 2,6-dinitro-4-(trifluoromethyl)phenoxysalicylaldoxime derivatives as novel antitubulin agents.

Zhong-Chang Wang, Hai‐Liang Zhu, Hai-bin Gong, 2012, Bioorganic & medicinal chemistry.

Potentiating 1-(2-hydroxypropyl)-2-styryl-5-nitroimidazole derivatives against antibacterial agents: design, synthesis and biology analysis.

Zhong-Chang Wang, Peng-Fei Wang, Hai‐Liang Zhu, 2013, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of new B-RafV600E kinase inhibitors.

Zhong-Chang Wang, Peng-Fei Wang, Hai‐Liang Zhu, 2018, Bioorganic & medicinal chemistry.

Improving effect of vegetation on the coastal salt marshes in Yancheng, Eastern China: A five-year observation (2013–2017)

Zhong-Chang Wang, S. An, Yu-Shun Yang, 2020 .

Clinical evaluation of plasma coagulation parameters in patients with advanced‐stage non‐small cell lung cancer treated with palliative chemotherapy in China

Zhong-Chang Wang, Said Abasse Kassim, M. Shi, 2020, International journal of clinical practice.

Design, synthesis, and biological evaluation of chrysin derivatives as potential FabH inhibitors

Zhong-Chang Wang, Hailiang Zhu, Hong-Xia Li, 2017, Chemical biology & drug design.

A novel fast-response and highly selective AIEgen fluorescent probe for visualizing peroxynitrite in living cells, C. elegans and inflammatory mice.

Zhong-Chang Wang, Baozhong Wang, Q. Jiao, 2021, The Analyst.

A class of novel tubulin polymerization inhibitors exert effective anti-tumor activity via mitotic catastrophe.

Zhong-Chang Wang, Yaliang Zhang, Ai-Qin Jiang, 2019, European journal of medicinal chemistry.

Identification and Biological Evaluation of Novel Type II B‐RafV600E Inhibitors

Zhong-Chang Wang, Peng-Fei Wang, Yue Huang, 2018, ChemMedChem.

Design of potent B‐RafV600E inhibitors by multiple copy simulation search strategy

Zhong-Chang Wang, Peng-Fei Wang, Baozhong Wang, 2018, Chemical biology & drug design.

Coumarin sulfonamides derivatives as potent and selective COX-2 inhibitors with efficacy in suppressing cancer proliferation and metastasis.

Zhong-Chang Wang, Shen-Zhen Ren, Fa-Qian Shen, 2016, Bioorganic & medicinal chemistry letters.

Design, synthesis, biological evaluation and molecular docking of novel metronidazole derivatives as selective and potent JAK3 inhibitors

Zhong-Chang Wang, Peng-Fei Wang, Jigar A. Makawana, 2014 .

A DNA-based nanocarrier for efficient cancer therapy

Zhong-Chang Wang, Yaliang Zhang, Yiqiao Hu, 2020, Journal of pharmaceutical analysis.

Novel metronidazole-sulfonamide derivatives as potent and selective carbonic anhydrase inhibitors: design, synthesis and biology analysis

Zhong-Chang Wang, Peng-Fei Wang, Y. Duan, 2014 .

Sulfonamides containing coumarin moieties selectively and potently inhibit carbonic anhydrases II and IX: design, synthesis, inhibitory activity and 3D-QSAR analysis.

Zhong-Chang Wang, Peng-Fei Wang, Ya-Juan Qin, 2013, European journal of medicinal chemistry.

Cu(II) and Co(II) ternary complexes of quinolone antimicrobial drug enoxacin and levofloxacin: structure and biological evaluation

Zhong-Chang Wang, Ji Li, Wanyun Huang, 2014 .

Ni(II) Ternary Complex Based on Antimicrobial Drug Enoxacin: Synthesis and Biological Properties

Zhong-Chang Wang, Wanyun Huang, Hailiang Zhu, 2014 .

Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents

Zhong-Chang Wang, Jigar A. Makawana, Y. Duan, 2016, Scientific Reports.

Synthesis of novel hybrids of pyrazole and coumarin as dual inhibitors of COX-2 and 5-LOX.

Zhong-Chang Wang, Baozhong Wang, Shen-Zhen Ren, 2017, Bioorganic & medicinal chemistry letters.

Synthesis, anticancer activity and molecular docking studies on 1,2-diarylbenzimidazole analogues as anti-tubulin agents.

Zhong-Chang Wang, Yaliang Zhang, Ai-Qin Jiang, 2019, Bioorganic chemistry.

Design, synthesis and biological evaluation of metronidazole-thiazole derivatives as antibacterial inhibitors.

Zhong-Chang Wang, Peng-Fei Wang, Ya-Juan Qin, 2014, Bioorganic & medicinal chemistry letters.

Synthesis, molecular docking and biological evaluation of 1‐phenylsulphonyl‐2‐(1‐methylindol‐3‐yl)‐benzimidazole derivatives as novel potential tubulin assembling inhibitors

Zhong-Chang Wang, Yaliang Zhang, Yan-Ting Wang, 2017, Chemical biology & drug design.

Dihydropyrazoles containing morpholine: design, synthesis and bioassay testing as potent antimicrobial agents

Zhong-Chang Wang, Peng-Fei Wang, Hai-bin Gong, 2015 .

Recent Progress in the Development of Small Molecule c-Met Inhibitors.

Zhong-Chang Wang, Yu-Shun Yang, Pengcheng Lv, 2019, Current topics in medicinal chemistry.

Design, synthesis and biological evaluation of novel ferrocene-pyrazole derivatives containing nitric oxide donors as COX-2 inhibitors for cancer therapy.

Zhong-Chang Wang, Shen-Zhen Ren, Xiao-Hua Zhu, 2018, European journal of medicinal chemistry.

Synthesis of Caffeic Acid Amides Bearing 2,3,4,5-Tetra-hydrobenzo[b][1,4]dioxocine Moieties and Their Biological Evaluation as Antitumor Agents

Zhong-Chang Wang, Peng-Fei Wang, Jigar A. Makawana, 2014, Molecules.

Structural Basis for the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase from Staphylococcus aureus and Escherichia coli.

J. Baell, Zhong-Chang Wang, T. Peat, 2016, Journal of medicinal chemistry.

Design, Synthesis and Biological Evaluation of Benzohydrazide Derivatives Containing Dihydropyrazoles as Potential EGFR Kinase Inhibitors

Zhong-Chang Wang, Hailiang Zhu, Hong-Xia Li, 2016, Molecules.

Design and synthesis of 2-styryl of 5-Nitroimidazole derivatives and antimicrobial activities as FabH inhibitors.

Zhong-Chang Wang, Peng-Fei Wang, Yong-Hua Yang, 2014, European journal of medicinal chemistry.

Clinical Evaluation of Serum Tumor Markers in Patients With Advanced-Stage Non-Small Cell Lung Cancer Treated With Palliative Chemotherapy in China

Zhong-Chang Wang, Yiqiao Hu, Said Abasse Kassim, 2020, Frontiers in Oncology.

Design, synthesis and biological evaluation of 2-H pyrazole derivatives containing morpholine moieties as highly potent small molecule inhibitors of APC-Asef interaction.

Zhong-Chang Wang, Guigen Li, Peng-fei Qi, 2019, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of novel benzo-α-pyrone containing piperazine derivatives as potential BRAFV600E inhibitors.

Zhong-Chang Wang, Long-wang Chen, Baozhong Wang, 2016, Bioorganic & medicinal chemistry letters.

Identification of novel 1‐indolyl acetate‐5‐nitroimidazole derivatives of combretastatin A‐4 as potential tubulin polymerization inhibitors

Zhong-Chang Wang, Y. Duan, Yongfang Yao, 2017, Biochemical pharmacology.

Design, synthesis and evaluation of novel diaryl-1,5-diazoles derivatives bearing morpholine as potent dual COX-2/5-LOX inhibitors and antitumor agents.

Zhong-Chang Wang, Shen-Zhen Ren, Zhang Li, 2019, European journal of medicinal chemistry.

Synthesis, Biological Evaluation, and Docking of Dihydropyrazole Sulfonamide Containing 2‐hydroxyphenyl Moiety: A Series of Novel MMP‐2 Inhibitors

Zhong-Chang Wang, Peng-Fei Wang, S. Baloch, 2015, Chemical biology & drug design.

Sulfonamide derivatives containing dihydropyrazole moieties selectively and potently inhibit MMP-2/MMP-9: Design, synthesis, inhibitory activity and 3D-QSAR analysis.

Zhong-Chang Wang, Peng-Fei Wang, Long-wang Chen, 2015, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of quinoline–imidazole hybrids as potent telomerase inhibitors: a promising class of antitumor agents

Zhong-Chang Wang, Jigar A. Makawana, Ai-Qin Jiang, 2014 .

A highly selective AIEgen fluorescent probe for visualizing Cys in living cells and C. elegans

Zhong-Chang Wang, Baozhong Wang, Q. Jiao, 2021, New Journal of Chemistry.

Design, synthesis and molecular docking of salicylic acid derivatives containing metronidazole as a new class of antimicrobial agents.

Zhong-Chang Wang, Peng-Fei Wang, Yong Yin, 2015, Bioorganic & medicinal chemistry.

Synthesis, biological evaluation, and molecular docking studies of novel 2-styryl-5-nitroimidazole derivatives containing 1,4-benzodioxan moiety as FAK inhibitors with anticancer activity.

Zhong-Chang Wang, Wei Huang, Jigar A. Makawana, 2014, Bioorganic & medicinal chemistry.

Design, synthesis, and biological evaluation of 2,3‐diphenyl‐cycloalkyl pyrazole derivatives as potential tubulin polymerization inhibitors

Zhong-Chang Wang, Yaliang Zhang, Baozhong Wang, 2019, Chemical biology & drug design.

Metronidazole containing pyrazole derivatives potently inhibit tyrosyl‐tRNA synthetase: design, synthesis, and biological evaluation

Zhong-Chang Wang, Peng-Fei Wang, Long-wang Chen, 2016, Chemical biology & drug design.

Tubulin inhibitors binding to colchicine-site: A Review from 2015 to 2019.

Zhong-Chang Wang, Yaliang Zhang, Baozhong Wang, 2019, Current medicinal chemistry.

Nanoscale Metal-Organic-Frameworks Coated by Biodegradable Organosilica for pH and Redox Dual Responsive Drug Release and High-Performance Anticancer Therapy.

Zhong-Chang Wang, Dan Zhu, Shen-Zhen Ren, 2019, ACS applied materials & interfaces.

An Oxygen Self-Sufficient Core-Shell Metal-Organic Framework-Based Smart Nanoplatform for Enhanced Synergistic Chemotherapy and Photodynamic Therapy.

Meilin Liu, Zhong-Chang Wang, Dan Zhu, 2020, ACS applied materials & interfaces.

Multifunctional Protein Hybrid Nanoplatform for Synergetic Photodynamic‐Chemotherapy of Malignant Carcinoma by Homologous Targeting Combined with Oxygen Transport

Zhong-Chang Wang, Shen-Zhen Ren, Y. Duan, 2022, Advanced science.

Dihydropyrazole Derivatives Containing Benzo Oxygen Heterocycle and Sulfonamide Moieties Selectively and Potently Inhibit COX-2: Design, Synthesis, and Anti-Colon Cancer Activity Evaluation

Zhong-Chang Wang, Guigen Li, Peng-fei Qi, 2019, Molecules.

Design, synthesis, evaluation and 3D-QSAR analysis of benzosulfonamide benzenesulfonates as potent and selective inhibitors of MMP-2

Zhong-Chang Wang, Yong-Hua Yang, Xiao-Ming Wang, 2014 .

Design, synthesis and evaluation of benzenesulfonamide-substituted 1,5-diarylpyrazoles containing phenylacetohydrazide derivatives as COX-1/COX-2 agents against solid tumors

Zhong-Chang Wang, Ting Wei, Hailiang Zhu, 2016 .

A new mitochondria-targeted fluorescent probe for exogenous and endogenous superoxide anion imaging in living cells and pneumonia tissue.

Zhong-Chang Wang, Q. Jiao, Hailiang Zhu, 2022, In Analysis.

Structure-based design and development of functionalized Mercaptoguanine derivatives as inhibitors of the folate biosynthesis pathway enzyme 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase from Staphylococcus aureus.

J. Baell, Zhong-Chang Wang, J. Newman, 2014, Journal of medicinal chemistry.

Design, synthesis, and biological evaluation of pyrazole derivatives containing acetamide bond as potential BRAFV600E inhibitors.

Zhong-Chang Wang, Ze-Feng Wang, Hailiang Zhu, 2018, Bioorganic & medicinal chemistry letters.

Dihydropyrazothiazole derivatives as potential MMP-2/MMP-8 inhibitors for cancer therapy.

Zhong-Chang Wang, Fa-Qian Shen, Ming-hua Wang, 2018, Bioorganic & medicinal chemistry letters.

EGFR/HER-2 inhibitors: synthesis, biological evaluation and 3D-QSAR analysis of dihydropyridine-containing thiazolinone derivatives

Zhong-Chang Wang, Ai-Qin Jiang, Xin A. Zhang, 2015 .

8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.

J. Baell, Zhong-Chang Wang, T. Peat, 2018, Chemistry.