D. Kojetin

Ian Mitchelle S. de Vera, D. Kojetin, Suzie Thenin-Houssier, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Regulation of Circadian Behavior and Metabolism by Synthetic REV-ERB Agonists

J. Takahashi, T. Hughes, D. Kojetin, 2012, Nature.

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers

Travis S. Hughes, Douglas J. Kojetin, Patrick R. Griffin, 2015, Nature Communications.

An alternate binding site for PPARγ ligands

Travis S. Hughes, Ian Mitchelle S. de Vera, Douglas J. Kojetin, 2014, Nature Communications.

DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex

Jun Zhang, Douglas J. Kojetin, Scott A. Busby, 2011, Nature Structural &Molecular Biology.

Structural and biophysical insights into the ligand-free Pitx2 homeodomain and a ring dermoid of the cornea inducing homeodomain mutant.

J. M. Baird-Titus, D. Kojetin, M. Rance, 2012, Biochemistry.

1H, 13C and 15N chemical shift assignments for the human Pitx2 homeodomain and a R24H homeodomain mutant

J. M. Baird-Titus, D. Kojetin, M. Rance, 2011, Biomolecular NMR assignments.

Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA.

Ian Mitchelle S. de Vera, Patrick R Griffin, David P Marciano, 2017, Structure.

Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space

Ian Mitchelle S. de Vera, D. Kojetin, E. Ortlund, 2015, Proceedings of the National Academy of Sciences.

Characterization of the Core Mammalian Clock Component, NPAS2, as a REV-ERBα/RORα Target Gene*

D. Kojetin, T. Burris, Yongjun Wang, 2010, The Journal of Biological Chemistry.

Alternative Splicing of a β4 Subunit Proline-Rich Motif Regulates Voltage-Dependent Gating and Toxin Block of Cav2.1 Ca2+ Channels

D. Kojetin, J. Cavanagh, Thomas D Helton, 2002, The Journal of Neuroscience.

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements

Ian Mitchelle S. de Vera, J. Nwachukwu, D. Kojetin, 2018, Nature Communications.

CAR directs T cell adaptation to bile acids in the small intestine

Mark S. Sundrud, D. Kojetin, D. Moore, 2021, Nature.

Constitutive androstane receptor directs T cell adaptation to bile acids in the small intestine

Mark S. Sundrud, D. Kojetin, D. Moore, 2020, bioRxiv.

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1.

Henry D. Wilson, Ian Mitchelle S. de Vera, T. Creamer, 2016, ACS chemical biology.

A molecular switch regulating transcriptional repression and activation of PPARγ

P. Griffin, D. Kojetin, S. Mosure, 2020, Nature Communications.

Chemical Crosslinking Mass Spectrometry Reveals the Conformational Landscape of the Activation Helix of PPARγ; a Model for Ligand-Dependent Antagonism.

P. Griffin, D. Kojetin, A. Blayo, 2018, Structure.

Systems Structural Biology Analysis of Ligand Effects on ERα Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.

O. Elemento, J. Nwachukwu, S. Srinivasan, 2017, Cell chemical biology.

Structural characterization of two-component signal transduction proteins and calbindin D28k.

D. Kojetin, 2006 .

Structural Analysis of Divalent Metals Binding to the Bacillus subtilis Response Regulator Spo0F: The Possibility for In Vitro Metalloregulation in the Initiation of Sporulation

J. Hoch, L. Benson, Stephen Naylor, 2005, Biometals.

A role for rev-erbα ligands in regulation of adipogenesis.

D. Kojetin, T. Burris, 2011, Current pharmaceutical design.

Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor.

D. Kojetin, J. Fuhrmann, T. Kamenecka, 2017, ACS chemical biology.

Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-Chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy.

Ian Mitchelle S. de Vera, T. Hughes, D. Kojetin, 2016, Journal of medicinal chemistry.

Calbindin D28K interacts with Ran-binding protein M: identification of interacting domains by NMR spectroscopy.

T. Craig, R. Kumar, D. Kojetin, 2003, Biochemical and biophysical research communications.

Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1

Ian Mitchelle S. de Vera, T. Hughes, P. Griffin, 2018, bioRxiv.

Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex

P. Griffin, D. Kojetin, K. Martemyanov, 2018, eLife.

Structural organization of a major neuronal G protein regulator , 1 the RGS 7G 5R 7 BP complex 2 3

P. Griffin, D. Kojetin, K. Martemyanov, 2022 .

PGRMC2 is an Intracellular Heme Chaperone Critical for Adipocyte Function

G. Siuzdak, R. Spreafico, D. Kojetin, 2019, Nature.

1H, 13C and 15N chemical shift assignments for the human Pitx2 homeodomain in complex with a 22-base hairpin DNA

J. M. Baird-Titus, D. Kojetin, M. Rance, 2012, Biomolecular NMR assignments.

1H, 13C and 15N chemical shift assignments for the human Pitx2 homeodomain in complex with a 22-base hairpin DNA

J. M. Baird-Titus, D. Kojetin, M. Rance, 2011, Biomolecular NMR Assignments.

N chemical shift assignments for the human Pitx 2 homeodomain and a R 24 H homeodomain mutant

J. M. Baird-Titus, D. Kojetin, M. Rance, 2011 .

Structure, binding interface and hydrophobic transitions of Ca2+-loaded calbindin-D28K

R. Kumar, D. Kojetin, J. Cavanagh, 2006, Nature Structural &Molecular Biology.

Quantitative structural assessment of graded receptor agonism

P. Griffin, D. Kojetin, T. Kamenecka, 2019, Proceedings of the National Academy of Sciences.

Defining a conformational ensemble that directs activation of PPARγ

Ian Mitchelle S. de Vera, T. Cheatham, T. Hughes, 2018, Nature Communications.

Defining a conformational ensemble that directs activation of PPARγ

Ian Mitchelle S. de Vera, T. Cheatham, T. Hughes, 2018, Nature Communications.

Assessment of NR4A Ligands that Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

Ian Mitchelle S. de Vera, D. Kojetin, T. Kamenecka, 2020, bioRxiv.

Structural Basis of Altered Potency and Efficacy Displayed by a Major in Vivo Metabolite of the Antidiabetic PPARγ Drug Pioglitazone.

P. Griffin, D. Kojetin, S. Mosure, 2019, Journal of medicinal chemistry.

Solution structure and dynamics of LuxU from Vibrio harveyi, a phosphotransferase protein involved in bacterial quorum sensing.

B. Bassler, D. Kojetin, J. P. Loria, 2004, Journal of molecular biology.

Molecular basis of ligand-dependent Nurr1-RXRα activation

D. Kojetin, J. Shang, Xiaoyu Yu, 2022, bioRxiv.

Technical Advance Three-Dimensional Imaging of Embryonic Mouse Kidney by Two-Photon Microscopy

S. Fang, D. Kojetin, A. Filson, 2000 .

A molecular switch regulating transcriptional repression and activation of PPARγ

P. Griffin, D. Kojetin, S. Mosure, 2020, Nature Communications.

Three-dimensional imaging of embryonic mouse kidney by two-photon microscopy.

D. Kojetin, A. Filson, K. Dunn, 2001, The American journal of pathology.

Activity-Based Profiling Reveals a Regulatory Link between Oxidative Stress and Protein Arginine Phosphorylation.

D. Kojetin, P. Thompson, V. Subramanian, 2016, Cell chemical biology.

Mechanistic insight into protein modification and sulfur mobilization activities of noncanonical E1 and associated ubiquitin‐like proteins of Archaea

D. Kojetin, S. Uthandi, D. Su, 2016, The FEBS journal.

Structure-function analysis of 1-hydroxypioglitazone, a major in vivo metabolite of the PPARγ agonist pioglitazone

D. Kojetin, S. Mosure, J. Shang, 2018 .

Structural organization of a major neuronal G protein regulator, the RGS7-Gβ5-R7BP complex

P. Griffin, D. Kojetin, K. Martemyanov, 2018, eLife.

Crystal Structure of RGS7-Gbeta5 dimer

P. Griffin, D. Kojetin, K. Martemyanov, 2018 .

REV-ERBα Regulates TH17 Cell Development and Autoimmunity

D. Kojetin, M. Cameron, S. Mosure, 2018, Cell reports.

Sub‐classification of response regulators using the surface characteristics of their receiver domains

D. Kojetin, J. Cavanagh, Richele J. Thompson, 2003, FEBS letters.

Classification of response regulators based on their surface properties.

D. Kojetin, J. Cavanagh, Richele J. Thompson, 2007, Methods in enzymology.

Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages.

D. Kojetin, Satyajit Das, A. Tarhini, 2024, Immunity.