S. Tye

发表

Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators

Steven V. Fox, J. Uslaner, J. Renger, 2013, Front. Neurosci..

The pharmacological properties of the imidazobenzodiazepine, FG 8205, a novel partial agonist at the benzodiazepine receptor

S. Iversen, E. Wong, J. Kemp, 1990, British journal of pharmacology.

Preclinical and clinical pharmacology of TPA023B, a GABAA receptor α2/α3 subtype-selective partial agonist

Sandra M. Sanabria-Bohórquez, G. Bormans, K. Van Laere, 2011, Journal of psychopharmacology.

Enhanced performance of spatial and visual recognition memory tasks by the selective acetylcholinesterase inhibitor E2020 in rhesus monkeys

S. Tye, M. J. Field, N. Rupniak, 1997, Psychopharmacology.

Drug-induced purposeless chewing: animal model of dyskinesia or nausea?

S. Iversen, S. Tye, N. Rupniak, 2005, Psychopharmacology.

NB-355: a novel prodrug for L-DOPA with reduced risk for peak-dose dyskinesias in MPTP-treated squirrel monkeys.

S. Iversen, S. Tye, N. Rupniak, 1989, Clinical neuropharmacology.

Blockade of CCK-B receptors by L-365,260 induces analgesia in the squirrel monkey

S. Iversen, S. Tye, C. Dourish, 1990, Brain Research.

Orexin receptor antagonist-induced sleep does not impair the ability to wake in response to emotionally salient acoustic stimuli in dogs

Steven V. Fox, J. Uslaner, J. Renger, 2014, Front. Behav. Neurosci..

Imidazo[1,2-b][1,2,4]triazines as α2/α3 subtype selective GABAA agonists for the treatment of anxiety

S. Tye, A. Pike, J. Atack, 2006 .

Comparison of the effects of selective and nonselective muscarinic agonists on cognition and thermoregulation in primates

S. Iversen, S. Tye, N. Rupniak, 1992, Journal of the Neurological Sciences.

TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine], an Agonist Selective for α2- and α3-Containing GABAA Receptors, Is a Nonsedating Anxiolytic in Rodents and Primates

G. Dawson, S. Tye, R. Mckernan, 2006, Journal of Pharmacology and Experimental Therapeutics.

Spontaneous orofacial dyskinesias in a captive cynomolgus monkey: Implications for tardive dyskinesia

S. Iversen, S. Tye, S. Boyce, 1990, Movement disorders : official journal of the Movement Disorder Society.

Behavioral and qEEG effects of the PDE10A inhibitor THPP-1 in a novel rhesus model of antipsychotic activity

Steven V. Fox, J. Uslaner, Sean M. Smith, 2016, Psychopharmacology.

The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold

Steven V. Fox, J. Uslaner, J. Renger, 2013, BMC Neuroscience.

Anxiolytic-like and antinociceptive effects of MK-801 accompanied by sedation and ataxia in primates

S. Iversen, S. Tye, S. Boyce, 1993, Pharmacology Biochemistry and Behavior.

Lack of effect of CCKB receptor antagonists in ethological and conditioned animal screens for anxiolytic drugs

G. Dawson, S. Iversen, S. Tye, 1995, Psychopharmacology.

Reversal of cognitive impairment by heptyl physostigmine, a long-lasting cholinesterase inhibitor, in primates

S. Iversen, S. Tye, N. Rupniak, 1992, Journal of the Neurological Sciences.

Heptylphysostigmine — Novel Acetylcholinesterase Inhibitor: Biochemical and Behavioral Pharmacology

G. Dawson, S. Iversen, L. Iversen, 1991 .

Orexin Receptor Antagonists Differ from Standard Sleep Drugs by Promoting Sleep at Doses That Do Not Disrupt Cognition

Steven V. Fox, Xiaohai Wang, Jason M. Uslaner, 2013, Science Translational Medicine.

Differential sleep-promoting effects of dual orexin receptor antagonists and GABAA receptor modulators

Steven V. Fox, J. Uslaner, J. Renger, 2014, BMC Neuroscience.

Quantitative Electroencephalography Within Sleep/Wake States Differentiates GABAA Modulators Eszopiclone and Zolpidem From Dual Orexin Receptor Antagonists in Rats

Steven V. Fox, J. Uslaner, J. Renger, 2013, Neuropsychopharmacology.

Evidence for a Significant Role of α3-Containing GABAA Receptors in Mediating the Anxiolytic Effects of Benzodiazepines

G. Dawson, R. Dias, S. Tye, 2005, The Journal of Neuroscience.

A Pyridazine Series of α2/α3 Subtype Selective GABAA Agonists for the Treatment of Anxiety

S. Tye, A. Pike, J. Atack, 2006 .

Discovery of imidazo[1,2-b][1,2,4]triazines as GABA(A) alpha2/3 subtype selective agonists for the treatment of anxiety.

S. Tye, A. Pike, J. Atack, 2006, Journal of medicinal chemistry.

MRK-409 (MK-0343), a GABAA receptor subtype-selective partial agonist, is a non-sedating anxiolytic in preclinical species but causes sedation in humans

G. Bormans, K. Van Laere, S. Tye, 2011, Journal of psychopharmacology.

Antiparkinsonian efficacy of a novel transdermal delivery system for (+)-PHNO in MPTP-treated squirrel monkeys

S. Iversen, S. Stahl, S. Tye, 1989, Neurology.

A pyridazine series of alpha2/alpha3 subtype selective GABA A agonists for the treatment of anxiety.

S. Tye, A. Pike, J. Atack, 2006, Journal of Medicinal Chemistry.

Failure of d-cycloserine to reverse cognitive disruption induced by scopolamine or phencyclidine in primates.

S. Iversen, S. Tye, G. Cook, 1992, Life sciences.

The novel NK1 receptor antagonist MK–0869 (L–754,030) and its water soluble phosphoryl prodrug, L–758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets

S. Tye, R. Hargreaves, F. D. Tattersall, 2000, Neuropharmacology.

Evidence against a specific effect of cholinergic drugs on spatial memory in primates

S. Iversen, S. Tye, M. J. Field, 1991, Behavioural Brain Research.

Behavioral and qEEG effects of the PDE10A inhibitor THPP-1 in a novel rhesus model of antipsychotic activity

Steven V. Fox, J. Uslaner, Sean M. Smith, 2016, Psychopharmacology.

Inhibition of Orexin Signaling Promotes Sleep Yet Preserves Salient Arousability in Monkeys.

Steven V. Fox, J. Uslaner, J. Renger, 2016, Sleep.