T. Mcdonald

发表

Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators

Steven V. Fox, J. Uslaner, J. Renger, 2013, Front. Neurosci..

Allosteric modulation of group III metabotropic glutamate receptor 4: A potential approach to Parkinson's disease treatment

A. Dilella, T. Mcdonald, J. Hess, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Identification of urotensin II as the endogenous ligand for the orphan G-protein-coupled receptor GPR14.

Jilly F. Evans, C. Austin, T. Mcdonald, 1999, Biochemical and biophysical research communications.

Discovery of highly potent and selective orexin 1 receptor antagonists (1-SORAs) suitable for in vivo interrogation of orexin 1 receptor pharmacology.

J. Renger, P. Coleman, A. Gotter, 2016, Bioorganic & medicinal chemistry letters.

Cloning of a novel G-protein-coupled receptor GPR 51 resembling GABAB receptors expressed predominantly in nervous tissues and mapped proximal to the hereditary sensory neuropathy type 1 locus on chromosome 9.

T. Mcdonald, P. Whiting, M. Rigby, 1999, Genomics.

Design, synthesis, and evaluation of novel 3,6-diaryl-4-aminoalkoxyquinolines as selective agonists of somatostatin receptor subtype 2.

T. Mcdonald, C. Lindsley, C. Thut, 2011, Journal of medicinal chemistry.

The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold

Steven V. Fox, J. Uslaner, J. Renger, 2013, BMC Neuroscience.

Discovery of 3-substituted aminocyclopentanes as potent and orally bioavailable NR2B subtype-selective NMDA antagonists.

A. Dilella, T. Mcdonald, D. Reiss, 2011, ACS chemical neuroscience.

Neuropeptide FF receptor 2 (NPFF2) is localized to pain-processing regions in the primate spinal cord and the lower level of the medulla oblongata

C. Austin, T. Mcdonald, Ruiping Wang, 2003, Journal of Chemical Neuroanatomy.

Identification and Characterization of Novel Mammalian Neuropeptide FF-like Peptides That Attenuate Morphine-induced Antinociception*

Jilly F. Evans, T. Mcdonald, Hong B. Yu, 2001, The Journal of Biological Chemistry.

Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R

Christopher P. Austin, Masahiko Ito, Alka Bansal, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Structures of active-state orexin receptor 2 rationalize peptide and small-molecule agonist recognition and receptor activation

M. Rudd, T. Mcdonald, S. Stachel, 2021, Nature Communications.

Identification of receptors for neuromedin U and its role in feeding

Christopher P. Austin, Jilly F. Evans, C. Thomas Caskey, 2000, Nature.

Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily.

T. Mcdonald, C. Caskey, Ruiping Wang, 1998, Biochemical and biophysical research communications.

Orexin Receptor Antagonists Differ from Standard Sleep Drugs by Promoting Sleep at Doses That Do Not Disrupt Cognition

Steven V. Fox, Xiaohai Wang, Jason M. Uslaner, 2013, Science Translational Medicine.

Differential sleep-promoting effects of dual orexin receptor antagonists and GABAA receptor modulators

Steven V. Fox, J. Uslaner, J. Renger, 2014, BMC Neuroscience.

Quantitative Electroencephalography Within Sleep/Wake States Differentiates GABAA Modulators Eszopiclone and Zolpidem From Dual Orexin Receptor Antagonists in Rats

Steven V. Fox, J. Uslaner, J. Renger, 2013, Neuropsychopharmacology.

FMRFamide-related neuropeptides are agonists of the orphan G-protein-coupled receptor GPR54.

C. Austin, T. Mcdonald, B. O'dowd, 2001, Biochemical and biophysical research communications.

Identification of two hERR2-related novel nuclear receptors utilizing bioinformatics and inverse PCR.

T. Mcdonald, C. Caskey, Q. Zhang, 1999, Gene.

Magnetic resonance imaging detects white adipose tissue beiging in mice following PDE10A inhibitor treatment

Sean M. Smith, T. Mcdonald, M. Tomaszewski, 2023, Journal of lipid research.

Pharmacological evaluation of orexin receptor antagonists in preclinical animal models of pain

J. Renger, P. Coleman, K. Smith, 2016, Journal of neurogenetics.