M. Metzler

M. Metzler, D. Parent-Massin, A. Gutleb, 2019, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Oxidative metabolism and genotoxic potential of major isoflavone phytoestrogens.

M. Metzler, S. Kulling, L. Lehmann, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Microtubular proteins as cellular targets for carcinogenic estrogens and other carcinogens.

M. Metzler, B. Epe, D. Schiffmann, 1989, Progress in clinical and biological research.

Catechol metabolites of the mycotoxin zearalenone are poor substrates but potent inhibitors of catechol-O-methyltransferase

M. Metzler, D. Wefers, S. C. Fleck, 2013, Mycotoxin Research.

Metabolism of stilbene estrogens and steroidal estrogens in relation to carcinogenicity

M. Metzler, 1984, Archives of Toxicology.

[Importance of chemico-biological interactions for the toxic and carcinogenic effect of aromatic amines. IV. Metabolic patterns of trans-4-demethylaminostilbene, cis-4-dimethylaminostilbene and 4-dimethylaminobibenzyl in liver, kidney and excretion products of the rat].

M. Metzler, H. Neumann, 1971, Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology.

Diethylstilbestrol metabolism by the fetal genital tract.

M. Metzler, J. McLachlan, R. Newbold, 1983, Endocrinology.

Genotoxicity of estrogens

M. Metzler, S. Kulling, E. Jacobs, 1998 .

In-Vitro Metabolites of Coumestrol

M. Metzler, S. Kulling, 1996 .

Cuticular hydrocarbons and female sex pheromones of the rove beetle, Aleochara curtula (Goeze) (Coleoptera:Staphylinidae)

M. Metzler, K. Peschke, 1987 .

Conjugation of the mycotoxins alternariol and alternariol monomethyl ether in tobacco suspension cells.

M. Metzler, M. Bunzel, D. Wefers, 2015, Journal of agricultural and food chemistry.

Zearalenone and its metabolites as endocrine disrupting chemicals

M. Metzler, E. Pfeiffer, A. Hildebrand, 2010 .

Total synthesis of alternariol.

M. Metzler, J. Podlech, E. Pfeiffer, 2005, The Journal of organic chemistry.

Assessment of decontamination processes for dioxins and dioxin‐like PCBs in fish oil by physical filtration with activated carbon

Heather M. Wallace, H. Knutsen, M. Metzler, 2017, EFSA journal. European Food Safety Authority.

Outcome of a public consultation on the draft scientific opinion on the health risks related to the presence of cyanogenic glycosides in foods other than raw apricot kernels

M. Metzler, D. Benford, T. Schwerdtle, 2019, EFSA Supporting Publications.

Assessment of a decontamination process for hydrocyanic acid in linseed intended for use in animal feed

Heather M. Wallace, H. Knutsen, M. Metzler, 2017, EFSA journal. European Food Safety Authority.

Sex hormones and neoplasia: genotoxic effects in short term assays.

M. Metzler, G. Degen, 1987, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

The mycotoxin patulin induces intra- and intermolecular protein crosslinks in vitro involving cysteine, lysine, and histidine side chains, and alpha-amino groups.

M. Metzler, R. Fliege, 1999, Chemico-biological interactions.

Influence of decreased intracellular glutathione level on the mutagenicity of patulin in cultured mouse lymphoma cells

M. Metzler, D. Schumacher, L. Lehmann, 2005, Mycotoxin Research.

Mutagenicity of the mycotoxin patulin in cultured Chinese hamster V79 cells, and its modulation by intracellular glutathione

M. Metzler, D. Schumacher, L. Lehmann, 2005, Archives of Toxicology.

Electrophilic properties of patulin. Adduct structures and reaction pathways with 4-bromothiophenol and other model nucleophiles.

M. Metzler, R. Fliege, 2000, Chemical research in toxicology.

Electrophilic properties of patulin. N-acetylcysteine and glutathione adducts.

M. Metzler, R. Fliege, Manfred Metzler, 2000, Chemical research in toxicology.

Aneuploidogenic and clastogenic potential of the mycotoxins citrinin and patulin.

M. Metzler, E. Pfeiffer, K. Gross, 1998, Carcinogenesis.

Bisphenol A and its methylated congeners inhibit growth and interfere with microtubules in human fibroblasts in vitro.

M. Metzler, L. Lehmann, 2004, Chemico-biological interactions.

Glucuronidation of curcuminoids by human microsomal and recombinant UDP-glucuronosyltransferases.

M. Metzler, E. Pfeiffer, Simone I Hoehle, 2007, Molecular nutrition & food research.

Curcuminoids form reactive glucuronides in vitro.

M. Metzler, A. Sólyom, E. Pfeiffer, 2007, Journal of agricultural and food chemistry.

Catechol formation: a novel pathway in the metabolism of sterigmatocystin and 11-methoxysterigmatocystin.

M. Metzler, S. C. Fleck, E. Pfeiffer, 2014, Chemical research in toxicology.

Assessment of an application on a detoxification process of groundnut press cake for aflatoxins by ammoniation

Heather M. Wallace, M. Metzler, D. Schrenk, 2021, EFSA journal. European Food Safety Authority.

Determination of the absolute configuration of perylene quinone-derived mycotoxins by measurement and calculation of electronic circular dichroism spectra and specific rotations.

M. Metzler, A. Ulrich, J. Bürck, 2014, Chemistry.

Oxidative metabolism of the mycotoxins alternariol and alternariol-9-methyl ether in precision-cut rat liver slices in vitro.

M. Metzler, B. Burkhardt, U. Schauer, 2011, Molecular nutrition & food research.

Activities of human recombinant cytochrome P450 isoforms and human hepatic microsomes for the hydroxylation ofAlternaria toxins

M. Metzler, B. Burkhardt, J. Podlech, 2008, Mycotoxin Research.

Mutagenicity of the mycotoxin alternariol in cultured mammalian cells.

M. Metzler, D. Schumacher, J. Podlech, 2006, Toxicology letters.

Mouse hepatoma cell lines differing in aryl hydrocarbon receptor-mediated signaling have different activities for glucuronidation

M. Metzler, B. Burkhardt, C. Weiss, 2012, Archives of Toxicology.

Absorption and metabolism of the mycotoxins alternariol and alternariol-9-methyl ether in Caco-2 cells in vitro

M. Metzler, B. Burkhardt, E. Pfeiffer, 2009, Mycotoxin Research.

Alternaria toxins: DNA strand-breaking activity in mammalian cellsin vitro

M. Metzler, S. Eschbach, E. Pfeiffer, 2007, Mycotoxin Research.

Estrogenic and clastogenic potential of the mycotoxin alternariol in cultured mammalian cells.

M. Metzler, L. Lehmann, J. Wagner, 2006, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Risk assessment of ochratoxin A in food

Heather M. Wallace, M. Metzler, D. Schrenk, 2020, EFSA journal. European Food Safety Authority.

Defensive and pheromonal secretion of the tergal gland of Aleochara curtula

M. Metzler, K. Peschke, 1982, Journal of Chemical Ecology.

Peroxidase Interfering Activity, An Endogenous Factor Able to Hinder The Biochemical Determination of Peroxidase

M. Metzler, J. C. Osborne, 1984 .

Effects of Estrogens on Microtubule Assembly: Significance for Aneuploidy

M. Metzler, M. Schuler, E. Pfeiffer, 1996 .

Oxidative metabolites of diethylstilbestrol in the fetal, neonatal and adult mouse.

M. Metzler, J. McLachlan, J. Mclachlan, 1978, Biochemical pharmacology.

Metabolic activation of carcinogenic diethylstilbestrol in rodents and humans.

M. Metzler, 1976, Journal of toxicology and environmental health. Supplement.

Alkaline phosphatase. 31P NMR probes of the mechanism.

M. Metzler, P. Gettins, J. Coleman, 1985, The Journal of biological chemistry.

Metabolic epoxidation of trans-4-acetylaminostilbene: a protective mechanism against its activation to a mutagen.

H. Glatt, F. Oesch, M. Metzler, 1976, Biochemical and biophysical research communications.

Epoxidation of the stilbene double bond, a major pathway in aminostilbene metabolism.

M. Metzler, H. Neumann, 1977, Xenobiotica; the fate of foreign compounds in biological systems.

Alternaria toxins: Altertoxin II is a much stronger mutagen and DNA strand breaking mycotoxin than alternariol and its methyl ether in cultured mammalian cells.

M. Metzler, B. Burkhardt, S. C. Fleck, 2012, Toxicology letters.

Estrogenic and genotoxic potential of equol and two hydroxylated metabolites of Daidzein in cultured human Ishikawa cells.

M. Metzler, L. Lehmann, J. Wagner, 2005, Toxicology letters.

Diethylstilbestrol metabolites and analogs. New probes for the study of hormone action.

M. Metzler, K. Korach, J. McLachlan, 1979, The Journal of biological chemistry.

Possible role of peroxidase in the diethylstilbestrol-induced lesions of the Syrian hamster kidney.

M. Metzler, J. McLachlan, J. Lamb, 1978, Life sciences.

Metabolic activation of diethylstilbestrol: Indirect evidence for the formation of a stilbene oxide intermediate in hamster and rat

M. Metzler, 1975 .

Oxidative metabolism of the soy isoflavones daidzein and genistein in humans in vitro and in vivo.

M. Metzler, S. Kulling, D. Honig, 2001, Journal of agricultural and food chemistry.

Bioactivation of tetrachloroethylene. Role of glutathione S-transferase-catalyzed conjugation versus cytochrome P-450-dependent phospholipid alkylation.

M. Metzler, W. Dekant, D. Henschler, 1987, Drug metabolism and disposition: the biological fate of chemicals.

Identification of S-1,2-dichlorovinyl-N-acetyl-cysteine as a urinary metabolite of trichloroethylene: a possible explanation for its nephrocarcinogenicity in male rats.

M. Metzler, W. Dekant, D. Henschler, 1986, Biochemical pharmacology.

Identification of S-1,2,2-trichlorovinyl-N-acetylcysteine as a urinary metabolite of tetrachloroethylene: bioactivation through glutathione conjugation as a possible explanation of its nephrocarcinogenicity.

M. Metzler, W. Dekant, D. Henschler, 1986, Journal of biochemical toxicology.

Metabolism and permeability of curcumin in cultured Caco-2 cells.

Romy K. Scheerle, M. Metzler, E. Pfeiffer, 2013, Molecular nutrition & food research.

Induction of micronuclei, DNA strand breaks and HPRT mutations in cultured Chinese hamster V79 cells by the phytoestrogen coumoestrol.

M. Metzler, S. Kulling, 1997, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Absorption and metabolism of the mycotoxin zearalenone and the growth promotor zeranol in Caco-2 cells in vitro.

M. Metzler, E. Pfeiffer, Julia S. Dempe, 2011, Molecular nutrition & food research.

The life of Hans-Günter Neumann and his contributions to chemical carcinogenesis

M. Metzler, G. Degen, A. Bitsch, 2020, Archives of Toxicology.

The tumor-inhibiting effect of diethylstilbestrol-3,4-oxide

M. Metzler, H. Schönenberger, G. Ruckdeschel, 2004, Journal of Cancer Research and Clinical Oncology.

Interaction of p-benzoquinone and p-biphenoquinone with microtubule proteins in vitro.

M. Metzler, E. Pfeiffer, 1996, Chemico-biological interactions.

Peroxidase-mediated oxidation, a possible pathway for metabolic activation of diethylstilbestrol.

M. Metzler, J. McLachlan, J. Mclachlan, 1978, Biochemical and biophysical research communications.

Metabolism of some anabolic agents: toxicological and analytical aspects.

M. Metzler, 1989, Journal of chromatography.

The use of the tergal gland defensive secretion in male intrasexual aggression of the rove beetle,Aleochara curtula (Coleoptera: Staphylinidae), measured by closed-loop-stripping-analyses and tandem bioassay — mass fragmentography

M. Metzler, P. Friedrich, K. Peschke, 1996, CHEMOECOLOGY.

Separation and identification of phase I and phase II [14C]antipyrine metabolites in rat and dog urine.

M. Metzler, I. Velić, H. Hege, 1995, Journal of chromatography. B, Biomedical applications.

Oxidative and conjugative metabolism of diethylstilbestrol by rabbit preimplantation embryos.

R. Balling, M. Metzler, H. Beier, 1985, Developmental Biology.

High-pressure, reverse-phase partition chromatograhy separation of diethylstilbestrol metabolites and analogs.

M. Metzler, R. Gottschlich, 1979, Analytical biochemistry.

Proposed nomenclature for diethylstilbestrol metabolites.

M. Metzler, J. McLachlan, 1978, Journal of environmental pathology and toxicology.

Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ERalpha) and ERbeta in human cells.

S. O. Mueller, S. Simon, K. Chae, 2004, Toxicological sciences : an official journal of the Society of Toxicology.

Hydroxylation of the mycotoxin zearalenone at aliphatic positions: novel mammalian metabolites

M. Metzler, E. Pfeiffer, A. Rapp, 2011, Mycotoxin Research.

Identification of an aliphatic epoxide and the corresponding dihydrodiol as novel congeners of zearalenone in cultures of Fusarium graminearum.

M. Metzler, Christine Becker, C. Syldatk, 2010, Journal of Agricultural and Food Chemistry.

Glucuronidation of zearalenone, zeranol and four metabolites in vitro: formation of glucuronides by various microsomes and human UDP-glucuronosyltransferase isoforms.

M. Metzler, H. Mikula, E. Pfeiffer, 2010, Molecular nutrition & food research.

Carcinogenic oestrogens induce respiration deficiency mutation in yeast.

M. Metzler, H. Stopper, 1991, Toxicology in vitro : an international journal published in association with BIBRA.

lternaria toxins : Altertoxin II is a much stronger mutagen and DNA strand reaking mycotoxin than alternariol and its methyl ether in cultured mammalian

M. Metzler, B. Burkhardt, E. Pfeiffer, 2012 .

Hydroxylation of the mycotoxin zearalenone at aliphatic positions: novel mammalian metabolites

M. Metzler, E. Pfeiffer, A. Rapp, 2012, Mycotoxin Research.

Induction of micronuclei by stilbene-type and steroidal estrogens in Syrian hamster embryo and ovine seminal vesicle cells in vitro.

M. Metzler, G. Degen, R. Schnitzler, 1994, Mutation research.

Identification and stereochemical characterization of lignans in flaxseed and pumpkin seeds.

M. Metzler, H. Niemeyer, D. Honig, 2003, Journal of agricultural and food chemistry.

Estrogenic activity in vivo and in vitro of some diethylstilbestrol metabolites and analogs.

M. Metzler, K. Korach, J. McLachlan, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Dose‐response studies of the induction of hyperdiploidy and polyploidy by diethylstilbestrol and 17β‐estradiol in cultured human lymphocytes using multicolor fluorescence in situ hybridization

M. Metzler, D. Eastmond, M. Schuler, 1998, Environmental and molecular mutagenesis.

Metabolism and lack of DNA reactivity of the mycotoxin ochratoxin a in cultured rat and human primary hepatocytes.

M. Metzler, K. Gross-Steinmeyer, H. Hege, 2002, Journal of agricultural and food chemistry.

Appropriateness to set a group health based guidance value for T2 and HT2 toxin and its modified forms

Heather M. Wallace, H. Knutsen, M. Metzler, 2017, EFSA journal. European Food Safety Authority.

EFSA's integrated approach to set a tolerable daily intake for zearalenone and its modified forms

M. Metzler, A. Gutleb, C. Dall’Asta, 2016 .

Nephrocarcinogenicity of estrogens.

M. Metzler, 1990, Toxicology letters.

Isoflavones modulate the glucuronidation of estradiol in human liver microsomes.

M. Metzler, E. Pfeiffer, Simone I Hoehle, 2005, Carcinogenesis.

Oxidative metabolites of diethylstilbestrol in the fetal Syrian golden hamster.

M. Metzler, R. Maydl, 1984, Teratology.

Structural Requirements for the in vitro Transformation of Syrian Hamster Embryo Cells by Stilbene Estrogens and Triphenylethylene‐Type Antiestrogens

M. Metzler, D. Schiffmann, 1991, American Journal of Clinical Oncology.

On the Biosynthesis of Juvenile Hormone in the Adult Cecropia Moth

M. Metzler, K. Dahm, H. Röller, 1971, Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete.

Metabolites of diethylstilboestrol induce sister chromatid exchange in human cultured fibroblasts

H. Glatt, F. Oesch, M. Metzler, 1979, Nature.

Glucuronidation of the mycotoxins alternariol and alternariol-9-methyl ether in vitro: chemical structures of glucuronides and activities of human UDP-glucuronosyltransferase isoforms

M. Metzler, B. Burkhardt, J. Podlech, 2009, Mycotoxin Research.

DNA damage and repair kinetics of the Alternaria mycotoxins alternariol, altertoxin II and stemphyltoxin III in cultured cells.

M. Metzler, A. Hartwig, B. Köberle, 2016, Mutation research. Genetic toxicology and environmental mutagenesis.

Molecular mechanism of 1,1-dichloroethylene toxicity: excreted metabolites reveal different pathways of reactive intermediates

M. Metzler, D. Henschler, H. Werner, 1978, Archives of Toxicology.

Carcinogenicity of trichloroethylene: fact or artifact?

M. Metzler, D. Henschler, E. Eder, 1977, Archives of Toxicology.

Covalent binding of reactive estrogen metabolites to microtubular protein as a possible mechanism of aneuploidy induction and neoplastic cell transformation.

M. Metzler, B. Epe, H. Stopper, 1990, Environmental health perspectives.

Absorption, elimination and metabolism of trichloroethylene: a quantitative comparison between rats and mice.

M. Metzler, W. Dekant, D. Henschler, 1986, Xenobiotica; the fate of foreign compounds in biological systems.

Identification of potential carcinogens in technical grade 1,1,1- trichloroethane

M. Metzler, D. Henschler, D. Reichert, 1980, International archives of occupational and environmental health.

Hormonal and genotoxic activity of resveratrol.

M. Metzler, H. Stopper, L. Lehmann, 2002, Toxicology letters.

A novel fluorinated derivative of diethylstilbestrol

M. Metzler, K. Korach, J. McLachlan, 1979, Steroids.

Metabolic fate of diethylstilbestrol in the Syrian golden hamster, a susceptible species for diethylstilbestrol carcinogenicity.

M. Metzler, R. Gottschlich, 1980, Xenobiotica; the fate of foreign compounds in biological systems.

Diethylstilbestrol metabolic transformation in relation to organ specific tumor manifestation.

M. Metzler, J. McLachlan, 1979, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

Role of metabolic activation in the carcinogenicity of estrogens: studies in an animal liver tumor model.

M. Metzler, A. Tritscher, G. Blaich, 1990, Environmental health perspectives.

Effect of pretreatment with 7,8-benzoflavone and diethylstilbestrol on the hepatic metabolism of diethylstilbestrol in the male Syrian golden hamster in vivo.

M. Metzler, G. Blaich, 1988, Biochemical pharmacology.

Metabolism of diethylstilbestrol in hamster hepatocytes.

M. Metzler, E. Pfaff, G. Blaich, 1987, Biochemical pharmacology.

Preparation of pentadeuterated diethylstilbestrol ([1, 1, 1, 2, 2‐D5] E‐3, 4‐di‐(4‐hydroxyphenyl)‐hex‐3‐ene)

M. Metzler, 1978 .

Synthesis of diethylstilbestrol metabolites : ω-hydroxy-dienestrol and derivatives

M. Metzler, 1978 .

Biotransformation of diethylstilbestrol in the rhesus monkey and the chimpanzee.

M. Metzler, W. Hobson, W. Müller, 1977, Journal of toxicology and environmental health.

Localization of diethylstilbestrol metabolites in the mouse genital tract.

M. Metzler, J. McLachlan, R. Newbold, 1985, Biochemical Pharmacology.

Dearylation and other cleavage reactions of diethylstilbestrol: novel oxidative pathways mediated by peroxidases.

M. Metzler, H. Haaf, 1985, Xenobiotica; the fate of foreign compounds in biological systems.

Is diethylstilbestrol bioactivated through peroxidase-mediated oxidation?

M. Metzler, J. McLachlan, 1978, Journal of Environmental Pathology And Toxicology.

Oxidative metabolism of the synthetic estrogens hexestrol and dienestrol indicates reactive intermediates.

M. Metzler, J. McLachlan, 1981, Advances in experimental medicine and biology.

Diethylstilbestrol and 11 derivatives: a mutagenicity study with Salmonella typhimurium.

H. Glatt, F. Oesch, M. Metzler, 1979, Mutation research.

Molecular structures of metabolites and analogues of diethylstilbestrol and their relationship to receptor binding and biological activity.

M. Metzler, K. Korach, J. McLachlan, 1984, Molecular pharmacology.

Effect of 7,8-benzoflavone pretreatment on diethylstilbestrol metabolism, drug-metabolising enzymes and the aromatic hydrocarbon (Ah) receptor in male hamster liver

M. Metzler, M. Göttlicher, G. Blaich, 1987, European Journal of Drug Metabolism and Pharmacokinetics.

Effects of various inducers on diethylstilbestrol metabolism, drug-metabolizing enzyme activities and the aromatic hydrocarbon (Ah) receptor in male Syrian golden hamster liver.

M. Metzler, M. Göttlicher, G. Blaich, 1990, Journal of steroid biochemistry.

Metabolic activation of diethylstilbestrol and 7,8-benzoflavone in hamster hepatocytes.

M. Metzler, G. Blaich, 1989, Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement.

In vitro metabolism of diethylstilbestrol by hepatic, renal and uterine microsomes of rats and hamsters. Effects of different inducers.

M. Metzler, H. Haaf, 1985, Biochemical pharmacology.

Modification of 7,8-benzoflavone metabolism in hamster liver and kidney microsomes by hepatic tumor inducing treatments.

M. Metzler, H. Raabe, G. Blaich, 1990, Carcinogenesis.

Influence of alpha-naphthoflavone on the metabolism and binding of ethinylestradiol in male Syrian hamster liver microsomes: possible role in hepatocarcinogenesis.

M. Metzler, J. Li, H. Haaf, 1988, Cancer research.

Ontogeny of peroxidase activity in epithelium and eosinophils of the mouse uterus.

M. Metzler, J. McLachlan, R. Newbold, 1991, Teratogenesis, carcinogenesis, and mutagenesis.

Different metabolism by mammalian and horseradish peroxidases in vitro of steroidal estrogens and their catechol metabolites.

M. Metzler, J. Zeeh, 1986, Journal of steroid biochemistry.

Peroxidase-mediated binding of diethylstilbestrol analogs to DNA in vitro: a possible role for a phenoxy radical.

M. Metzler, B. Epe, 1984, Chemico-biological interactions.

Morphological transformation of Syrian hamster embryo fibroblasts by the anabolic agent trenbolone

M. Metzler, D. Schiffmann, D. Henschler, 1985, Archives of Toxicology.

Mammalian cell transformation and aneuploidy induced by five bisphenols

M. Metzler, T. Tsutsui, Y. Tamura, 2000, International journal of cancer.

DNA reactivity of altertoxin II: Identification of two covalent guanine adducts formed under cell-free conditions.

M. Metzler, S. Kulling, S. C. Fleck, 2020, Toxicology letters.

Notizen: Biosynthesis of Juvenile Hormone from 10-epoxy-7-ethyl-3,11-dimethyl-2,6-tridecadienoic Acid in the Adult Cecropia Moth

M. Metzler, K. Dahm, H. Röller, 1972, Zeitschrift fur Naturforschung. Teil B. Anorganische Chemie, organische Chemie, Biochemie, Biophysik, Biologie.

Endocrine Disruptors – Part II

M. Metzler, 2001 .

In vitro mammalian metabolism of the mitosis inhibitor zoxamide and the relationship to its in vitro toxicity

F. Oesch, M. Metzler, G. Damm, 2010, Xenobiotica; the fate of foreign compounds in biological systems.

Excretion pattern and metabolism of hexachlorobutadiene in rats. Evidence for metabolic activation by conjugation reactions.

S. Schütz, M. Metzler, D. Reichert, 1985, Biochemical pharmacology.

Biochemical systematics and evolution of the European Heptageniidae (Ephemeroptera)

M. Metzler, I. Tomka, A. Zurwerra, 1987, Archiv für Hydrobiologie.

Microsomal hydroxylation and glucuronidation of [6]-gingerol.

M. Metzler, E. Pfeiffer, S. Kranz, 2006, Journal of agricultural and food chemistry.

Induction of Micronucleation, Spindle Disturbances, and Mitotic Arrest in Human Chorionic Villi Cells by 17ß-Estradiol, Diethylstilbestrol, and Coumestrol

M. Metzler, K. Huber, M. Schuler, 1996 .

Oxidative metabolites of the mammalian lignans enterodiol and enterolactone in rat bile and urine.

M. Metzler, S. Kulling, E. Jacobs, 2000, Journal of agricultural and food chemistry.

Patulin reduces glutathione level and enzyme activities in rat liver slices.

M. Metzler, E. Pfeiffer, Tabea T Diwald, 2005, Molecular nutrition & food research.

Chemistry of Natural and Anthropogenic Endocrine Active Compounds

M. Metzler, Manfred Metzler, Erika Pfeiffer, 2001 .

Metabolic activation of diethylstilbestrol and aminostilbene-derivatives

M. Metzler, H. Neumann, W. Töpner, 1977, Archives of Toxicology.

Genotoxic potential of xenobiotic growth promoters and their metabolites

M. Metzler, E. Pfeiffer, 2001 .

Genotoxic potential of xenobiotic growth promoters and their metabolites Note

M. Metzler, E. Pfeiffer, 2001, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Novel metabolites of the mammalian lignans enterolactone and enterodiol in human urine

M. Metzler, S. Kulling, E. Jacobs, 1999, The Journal of Steroid Biochemistry and Molecular Biology.

Oxidative metabolism of the mammalian lignans enterolactone and enterodiol by rat, pig, and human liver microsomes.

M. Metzler, E. Jacobs, 1999, Journal of Agricultural and Food Chemistry.

Metabolic activation of xenobiotic stilbene estrogens.

M. Metzler, 1987, Federation proceedings.

Effects of estrogens on microtubule polymerization in vitro: correlation with estrogenicity.

M. Metzler, E. Pfeiffer, Marcus Metzler, 1995, Environmental health perspectives.

Possible role of oxygen radicals in cell transformation by diethylstilbestrol and related compounds.

M. Metzler, B. Epe, D. Schiffmann, 1986, Carcinogenesis.

Biosynthesis and Degradation of Juvenile Hormone

M. Metzler, K. Dahm, H. Röller, 1974 .

Decontamination process for dioxins and dioxin‐like PCBs from fish oil and vegetable oils and fats by a physical process with activated carbon

Heather M. Wallace, M. Metzler, D. Schrenk, 2022, EFSA journal. European Food Safety Authority.

Oxidative metabolites and genotoxic potential of mammalian and plant lignans in vitro.

M. Metzler, H. Niemeyer, 2002, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Oxidative metabolism of lignans.

M. Metzler, L. Thompson, S. Cunnane, 2003 .

O x i d a t i ve Metabolism of Lignans

M. Metzler, 2003 .

Role of metabolic activation in the transplacental carcinogenicity of diethylstilbestrol.

M. Metzler, 1982, International journal of biological research in pregnancy.

Covalent binding of diethylstilbestrol to microsomal protein in vitro correlates with the organotropism of its carcinogenicity.

M. Metzler, H. Haaf, 1985, Carcinogenesis.

on the presence of dioxins (PCDD/Fs) and dioxin-like PCBs (DL-PCBs) in commercially available foods for infants and young

H. Knutsen, M. Metzler, D. Schrenk, 2013 .

Scientific Opinion on Tropane alkaloids in food and feed

H. Knutsen, M. Metzler, D. Schrenk, 2013 .

Genotoxicity and inactivation of catechol metabolites of the mycotoxin zearalenone

M. Metzler, S. C. Fleck, E. Pfeiffer, 2012, Mycotoxin Research.

Influence of a-Naphthoflavone on the Metabolism and Binding of Ethinylestradiol in Male Syrian Hamster Liver Microsomes: Possible Role in Hepatocarcinogenesis1

M. Metzler, J. Li, Jonathan, 2006 .

Rapid increase of the human IFN-gamma receptor phosphorylation in response to human IFN-gamma and phorbol myristate acetate. Involvement of different serine/threonine kinases.

M. Metzler, R. Ballotti, M. Aguet, 1990, Journal of immunology.

Appropriateness to set a group health based guidance value for nivalenol and its modified forms

Heather M. Wallace, H. Knutsen, M. Metzler, 2017, EFSA journal. European Food Safety Authority.

Properties of Micronuclei Induced by Various Estrogens in Two Different Mammalian Cell Systems

M. Metzler, R. Schnitzler, 1992 .

Indanyl analogs of diethylstilbestrol: differential interaction with prostaglandin H synthase.

M. Metzler, G. Degen, 1989, Carcinogenesis.

Appropriateness to set a group health‐based guidance value for fumonisins and their modified forms

Heather M. Wallace, H. Knutsen, M. Metzler, 2018, EFSA journal. European Food Safety Authority.

Nonrandom karyotypic changes in a spontaneously immortalized and tumourigenic Syrian hamster embryo cell line.

M. Metzler, L. Hieber, S. Endo, 1994, Carcinogenesis.

Estrogenic activity in vivo and in v metabolites and analogs (diethylstilbestrol metabolism/estrogen receptor/mouse uterus/)

M. Metzler, K. Korach, Hn A. Mclachlan, 2016 .

Catechol metabolites of the mycotoxin zearalenone are poor substrates but potent inhibitors of catechol-O-methyltransferase

M. Metzler, D. Wefers, S. C. Fleck, 2013, Mycotoxin Research.

Catechol metabolites of zeranol and 17β-estradiol: a comparative in vitro study on the induction of oxidative DNA damage and methylation by catechol-O-methyltransferase.

M. Metzler, S. C. Fleck, E. Pfeiffer, 2012, Toxicology letters.

Effects of novel 3,4-bisphenylhex(3)enes on cell proliferation in malignant and normal cells.

M. Metzler, M. Slaný, M. Schuler, 1996, Cancer Letters.

Bisphenol-A Disturbs Microtubule Assembly and Induces Micronuclei In Vitro

M. Metzler, E. Pfeiffer, B. Rosenberg, 1996 .

Effects of Steroidal and Stilbene Estrogens and Their Peroxidative Metabolites on Microtubular Proteins

M. Metzler, E. Pfeiffer, 1992 .

Diethylstilbestrol: evidence for metabolic activation in man, rat, and hamster.

M. Metzler, 1979, National Cancer Institute monograph.

Diethylstilbestrol: hormonal or chemical carcinogen?

M. Metzler, 1982 .

The life of Hans-Günter Neumann and his contributions to chemical carcinogenesis

M. Metzler, G. Degen, A. Bitsch, 2020, Archives of Toxicology.

Permeation and metabolism of Alternaria mycotoxins with perylene quinone structure in cultured Caco-2 cells

M. Metzler, S. C. Fleck, E. Pfeiffer, 2013, Mycotoxin Research.

Absorption and metabolism of the mycotoxin zearalenone and the growth promotor zeranol in Caco-2 cells in vitro.

M. Metzler, E. Pfeiffer, Julia S. Dempe, 2011, Molecular Nutrition & Food Research.

A Case of a Laboratory Animal Feed with High Estrogenic Activity and Its Impact on in Vivo Responses to Exogenously Administered Estrogens

Hansen, M. Metzler, F. Olea-Serrano, 1998, Environmental Health Perspectives.